Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas最新文献_第2页

alidation of an analytical method by HPLC for the quantification of yangambin from the Ocotea duckei species 用高效液相色谱法验证定量分析 Ocotea duckei 物种中洋姜素的分析方法

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.09

L. Peixoto, J. V. Chaves Junior, F. Andrade, I. Basílio, Fabio Santos de Souza, J. Barbosa Filho

{"title":"alidation of an analytical method by HPLC for the quantification of yangambin from the Ocotea duckei species","authors":"L. Peixoto, J. V. Chaves Junior, F. Andrade, I. Basílio, Fabio Santos de Souza, J. Barbosa Filho","doi":"10.37360/blacpma.24.23.1.09","DOIUrl":"https://doi.org/10.37360/blacpma.24.23.1.09","url":null,"abstract":"Ocotea duckei, known as Louro-de-cheiro, belongs to the Lauraceae family and presents lignoid yangambine (YAN) as the main plant marker. This work aimed to develop and validate an analytical method by high performance liquid chromatography for the quantification of YAN. The sample used was the crude ethanolic extract (CEE) obtained from aerial parts. In the developed method, a C18 column was used. The mobile phase was composed of acetonitrile and water (45:55), whereas the method parameters included mobile phase flow rate at 0.8 mL/min, oven temperature at 40°C, and monitoring at 205 nm. In the validation, the parameters of selectivity, linearity, precision, accuracy, robustness, limits of detection and quantification were evaluated. As a result, the developed method is in accordance with the guidelines for validation of analytical methods and presented satisfactory chromatographic parameters for YAN determination. Thus, the present analytical methodology can be applied in the quality control of O. duckei raw materials.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

cute sarcoidosis Löfgren Syndrome treated by Chinese medicinal formula based on Syndrome Differentiation: A case-based review 基于综合征分型的中药方剂治疗可爱的肉样瘤洛夫格伦综合征：基于病例的综述

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.1

Xue Li, Jian Liu, M. Liu, Min Liu, Yu-Guang Wang

引用次数: 0

The infusion of Baccharis spicata(Lam.) Baill (Asteraceae) has antiviral activity againsthepatitis B virus without cytotoxic effects against several cell lines 百日草（菊科）泡腾片对乙型肝炎病毒具有抗病毒活性，对多种细胞株无细胞毒性作用

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.11

Joseph T Ortega, Ignacio Agudelo, R. Ricco, L. Cavallaro, Rodolfo Campos

引用次数: 0

Ecotoxic and preventive effect of the use of essential oils in bovine mastitis 在牛乳腺炎中使用精油的生态毒性和预防效果

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.3

Jovanna M Suarez-Barreiro, Martha C. Suarez, Fabian Parada

引用次数: 0

Identification of cancer inhibitors from Hystrix brachyurabezoar extracts using LC-MS multivariate data analysis and in silico evaluation on Bcl-2, cyclin B/CDK1, VEGF and NM23-H1 利用 LC-MS 多变量数据分析和对 Bcl-2、细胞周期蛋白 B/CDK1、血管内皮生长因子和 NM23-H1 的硅学评估，从 Hystrix brachyurabezoar 提取物中鉴定癌症抑制剂

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.4

Al'aina Yuhainis Firus Khan, Q. Ahmed, A. Khatib, Z. Ibrahim, Tanzina Sharmin Nipun, H. A. Natto, Mohd Zuwairi Saiman, Z. Zakaria, R. A. Wahab

{"title":"Identification of cancer inhibitors from Hystrix brachyurabezoar extracts using LC-MS multivariate data analysis and in silico evaluation on Bcl-2, cyclin B/CDK1, VEGF and NM23-H1","authors":"Al'aina Yuhainis Firus Khan, Q. Ahmed, A. Khatib, Z. Ibrahim, Tanzina Sharmin Nipun, H. A. Natto, Mohd Zuwairi Saiman, Z. Zakaria, R. A. Wahab","doi":"10.37360/blacpma.24.23.1.4","DOIUrl":"https://doi.org/10.37360/blacpma.24.23.1.4","url":null,"abstract":"Hystrix brachyurabezoar is calcified undigested material found in the gastrointestinal tract known for various medicinal benefits including as an anticancer agent. However, the H. brachyurapopulation has been declining due to its demand and is under Malaysian law protection. Therefore, present study aimed to identify bezoar anticancer active compounds through metabolomics and in-silico approaches. Five replicates of bezoar powder were subjected to extraction using different solvent ratios of methanol-water (100, 75, 50, 25, 0% v/v). Cytotoxicity and metabolite profiling using liquid chromatography-mass spectrometry were conducted. Putative compounds identified were subjected to in-silico analysis with targeted anticancer proteins namely, Bcl-2, Cyclin B/CDK1 complex, VEGF and NM23-H1. The correlation of LC-MS and cytotoxicity profile pinpointed two compounds, mangiferin and propafenone. In-silicostudy showed both compounds exerted good binding scores to all proteins with hydrophobic interaction dominating the ligand-protein complex binding, suggesting the ligands act as hydrophobes in the interactions.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"12 46","pages":""},"PeriodicalIF":0.7,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuropharmacological and anxiolytic effects of extracts of Passiflora tripartita var. mollissima on mice 西番莲变种 mollissima 提取物对小鼠的神经药理学和抗焦虑作用

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.7

C. Marín-Tello, Jenner Gil-Velasquez, Dennis Diaz-Espinoza, Acxel Gil-Velasquez, J. Vasquez-Kool

{"title":"Neuropharmacological and anxiolytic effects of extracts of Passiflora tripartita var. mollissima on mice","authors":"C. Marín-Tello, Jenner Gil-Velasquez, Dennis Diaz-Espinoza, Acxel Gil-Velasquez, J. Vasquez-Kool","doi":"10.37360/blacpma.24.23.1.7","DOIUrl":"https://doi.org/10.37360/blacpma.24.23.1.7","url":null,"abstract":"Anxiety and depression cause alterations in the physiology of an organism. Extracts from the leaves of several Passiflora species are traditionally used Peru and in many countries as anxiolytic and in treatment for inflammatory problems. This study aimed to determine the neuropharmacological effect of the ethanolic extract of Passiflora tripartita var. mollissima (Kunth) Holm-Niels. & P.Jørg. and its anxiolytic effect on mouse (Mus musculus var. albinus). Anxiety was evaluated with the marble burying test and the depressant effect with the Irwin test (locomotor activity, base of support, wobbly gait, immobility, escape, ease of handling, muscular strength, tight rope, inclined plane, catatonia, nociceptive reflex and death). Doses of 100 mg/Kg/body weight and 200 mg/kg/body weight by intraperitoneal route (i.p.) significantly decreased anxiety levels (p<0.05) in mice, and had a non-significant depressant effect in 11 of the 12 tests, showing a similar direction of correlation between diazepam and Passiflora extract effect. A greater anxiolytic and anti-depressant effects in mice was observed with the extract dose of 200 mg/kg/body weight with neuropharmacological manifestations found where no death was observed at any dose used.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"4 5","pages":""},"PeriodicalIF":0.7,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethnobotany of the old neighborhoods from Guadalajara, Jalisco, Mexico: the use of medicinal plants 墨西哥哈利斯科州瓜达拉哈拉老区的人种植物学：药用植物的使用

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.6

Rosa Elena Martinez-Gonzalez, F. M. Huerta Martínez, Cecilia Neri Luna, Lucia Barrientos Ramirez

引用次数: 0

Oxytocin neuron activation by acute infusion of Montanoa genus plants in the Wistar rats 给 Wistar 大鼠急性注射 Montanoa 属植物激活催产素神经元

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.8

M. J. Rovirosa-Hernández, J. Rodríguez-Landa, Mario Caba, F. Garcia-Orduna, J. Cueto-Escobedo, D. Hernandez-Baltazar, Omar Lagunes-Merino

{"title":"Oxytocin neuron activation by acute infusion of Montanoa genus plants in the Wistar rats","authors":"M. J. Rovirosa-Hernández, J. Rodríguez-Landa, Mario Caba, F. Garcia-Orduna, J. Cueto-Escobedo, D. Hernandez-Baltazar, Omar Lagunes-Merino","doi":"10.37360/blacpma.24.23.1.8","DOIUrl":"https://doi.org/10.37360/blacpma.24.23.1.8","url":null,"abstract":"In traditional Mexican medicine, plants from the Montanoa genus, family Asteraceae (Montanoa tomentosa, Montanoa grandiflora, and Montanoa frutescens) have been used to induce labor owing to their uterotonic properties like those produced by oxytocin (OXT). However, whether infusions of these plants can activate hypothalamic OXT-producing neurons is unknown. To test this possibility, five independent groups of Wistar rats (n=4) were included: intact, vehicle, and three groups that received 50 mg/kg p.o. of M. tomentosa, M. grandiflora, and M. frutescens infusions, respectively. Ninety min after treatment, the brains were obtained and processed using double-labeled immunohistochemistry for Fos protein and oxytocin (Fos/OXT-ir). Rats that received Montanoa infusions had significantly greater number of Fos/OXT-ir cells in the paraventricular (PVN) and supraoptic (SON) nuclei, with respect to intact and vehicle groups. These findings demonstrate that Montanoa infusions activated OXT neurons, an effect that may be related to the reported pharmacological properties.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"2 3","pages":""},"PeriodicalIF":0.7,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioactivity of Myrtus communis from the Montenegro coastline 黑山海岸线上的香桃木的生物活性

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.5

Dusan Bugarin, D. Mitić-Ćulafić, E. Svirčev, M. Šundiċ, Neda M Mimica-Dukic

{"title":"Bioactivity of Myrtus communis from the Montenegro coastline","authors":"Dusan Bugarin, D. Mitić-Ćulafić, E. Svirčev, M. Šundiċ, Neda M Mimica-Dukic","doi":"10.37360/blacpma.24.23.1.5","DOIUrl":"https://doi.org/10.37360/blacpma.24.23.1.5","url":null,"abstract":"Although numerous studies have demonstrated the biomedical potential of Myrtus communisL., (Myrtaceae) data on myrtle from Montenegro are scarce. To evaluate antioxidant, antimutagenic and antibacterial activity of myrtle methanolic extracts. Antioxidant activity was evaluated by measuring free radicals scavenging activity, reducing power and enzyme inhibition. The strongest scavenging activity was towards DPPH radical (2,2-diphenyl-1-picrylhydrazyl) (IC501.69-2.25 mg/mL) and superoxide anion (IC500.56 to 0.88 mg/mL), followed by high reducing power (428-472 mgAA/g.DE) and inhibition of XOD (IC500.308-0.6261mg/mL). Antimutagenic activity was evaluated in reverse mutation assays with Escherichia coliWP2 oxyR mutant IC202 and deficient in the induction of antioxidant enzymes. The myrtle extracts strongly inhibited mutagenesis induced by t-BOOH, reaching 70% at the highest concentration applied. Antimicrobial activity was examined on eight different bacterial strains. Gram-positive bacteria, S. epidermis, S. aureusand M. flavus demonstrated the highest sensitivity towards extracts (MICs 4.5-9 mg/mL), but significantly lower towards essential oil (MIC 0.42-3.32 mg/mL).","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"2 12","pages":""},"PeriodicalIF":0.7,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development, characterization and anti-Mycobacterium tuberculosisactivity of solid lipid nanoparticles for oral Piper corcovadensisroots extract delivery 口服胡椒根提取物固体脂质纳米颗粒的研制、表征和抗结核分枝杆菌活性

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-11-30 DOI: 10.37360/blacpma.23.22.6.55

Carla María Mariano Fernandez, Sirlene Adriana Kleinubing, T. K. Karam, F. Lorenzetti, C. T. Palomo, Byanca Pereira Moreira de Oliveira, Odinei Hess Gonçalves, Zilda Cristiani Gazim, Mariza Barion Romagnolo, K. R. Caleffi-Ferracioli, Regiane Bertin de Lima Scodro, Marli Miriam de Souza Lima, T. U. Nakamura, C. V. Nakamura, B. P. D. Filho

{"title":"Development, characterization and anti-Mycobacterium tuberculosisactivity of solid lipid nanoparticles for oral Piper corcovadensisroots extract delivery","authors":"Carla María Mariano Fernandez, Sirlene Adriana Kleinubing, T. K. Karam, F. Lorenzetti, C. T. Palomo, Byanca Pereira Moreira de Oliveira, Odinei Hess Gonçalves, Zilda Cristiani Gazim, Mariza Barion Romagnolo, K. R. Caleffi-Ferracioli, Regiane Bertin de Lima Scodro, Marli Miriam de Souza Lima, T. U. Nakamura, C. V. Nakamura, B. P. D. Filho","doi":"10.37360/blacpma.23.22.6.55","DOIUrl":"https://doi.org/10.37360/blacpma.23.22.6.55","url":null,"abstract":"The present study thus aimed at the development and physicochemical characterization of solid lipid nanoparticles loaded with crude extract of Piper corcovadensisroots (SLN-CEPc) and chitosan-coated solid lipid nanoparticles loaded withcrude extract of P. corcovadensisroots (C-SLN-CEPc), as well as the determination of its antimycobacterial activity against Mycobacterium tuberculosisH37Rv, its cytotoxicity against the Vero cell line and evaluation in the hemolysis assay. Both formulations containing the encapsulated extract showed high encapsulation efficiency, formed by a monodispersed system with small and spherical particles, and there was no aggregation of particles. In the biological assays, SLN-CEPc and C-SLN-CEPc showed promising anti-M. tuberculosisactivity with a minimum inhibitory concentration (MIC) of 12.5 μg/mL, whereas the cytotoxic concentrations obtained at 50% (CC50) in Vero cells were 60.0 and 70.0 μg/mL, respectively. Therefore, nanoencapsulation showed satisfactory results, justifying its usage in the development of new products.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"33 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79895581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0