Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas最新文献_第2页

Ethnobotany of the old neighborhoods from Guadalajara, Jalisco, Mexico: the use of medicinal plants 墨西哥哈利斯科州瓜达拉哈拉老区的人种植物学：药用植物的使用

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.6

Rosa Elena Martinez-Gonzalez, F. M. Huerta Martínez, Cecilia Neri Luna, Lucia Barrientos Ramirez

引用次数: 0

Oxytocin neuron activation by acute infusion of Montanoa genus plants in the Wistar rats 给 Wistar 大鼠急性注射 Montanoa 属植物激活催产素神经元

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.8

M. J. Rovirosa-Hernández, J. Rodríguez-Landa, Mario Caba, F. Garcia-Orduna, J. Cueto-Escobedo, D. Hernandez-Baltazar, Omar Lagunes-Merino

{"title":"Oxytocin neuron activation by acute infusion of Montanoa genus plants in the Wistar rats","authors":"M. J. Rovirosa-Hernández, J. Rodríguez-Landa, Mario Caba, F. Garcia-Orduna, J. Cueto-Escobedo, D. Hernandez-Baltazar, Omar Lagunes-Merino","doi":"10.37360/blacpma.24.23.1.8","DOIUrl":"https://doi.org/10.37360/blacpma.24.23.1.8","url":null,"abstract":"In traditional Mexican medicine, plants from the Montanoa genus, family Asteraceae (Montanoa tomentosa, Montanoa grandiflora, and Montanoa frutescens) have been used to induce labor owing to their uterotonic properties like those produced by oxytocin (OXT). However, whether infusions of these plants can activate hypothalamic OXT-producing neurons is unknown. To test this possibility, five independent groups of Wistar rats (n=4) were included: intact, vehicle, and three groups that received 50 mg/kg p.o. of M. tomentosa, M. grandiflora, and M. frutescens infusions, respectively. Ninety min after treatment, the brains were obtained and processed using double-labeled immunohistochemistry for Fos protein and oxytocin (Fos/OXT-ir). Rats that received Montanoa infusions had significantly greater number of Fos/OXT-ir cells in the paraventricular (PVN) and supraoptic (SON) nuclei, with respect to intact and vehicle groups. These findings demonstrate that Montanoa infusions activated OXT neurons, an effect that may be related to the reported pharmacological properties.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioactivity of Myrtus communis from the Montenegro coastline 黑山海岸线上的香桃木的生物活性

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2024-01-30 DOI: 10.37360/blacpma.24.23.1.5

Dusan Bugarin, D. Mitić-Ćulafić, E. Svirčev, M. Šundiċ, Neda M Mimica-Dukic

{"title":"Bioactivity of Myrtus communis from the Montenegro coastline","authors":"Dusan Bugarin, D. Mitić-Ćulafić, E. Svirčev, M. Šundiċ, Neda M Mimica-Dukic","doi":"10.37360/blacpma.24.23.1.5","DOIUrl":"https://doi.org/10.37360/blacpma.24.23.1.5","url":null,"abstract":"Although numerous studies have demonstrated the biomedical potential of Myrtus communisL., (Myrtaceae) data on myrtle from Montenegro are scarce. To evaluate antioxidant, antimutagenic and antibacterial activity of myrtle methanolic extracts. Antioxidant activity was evaluated by measuring free radicals scavenging activity, reducing power and enzyme inhibition. The strongest scavenging activity was towards DPPH radical (2,2-diphenyl-1-picrylhydrazyl) (IC501.69-2.25 mg/mL) and superoxide anion (IC500.56 to 0.88 mg/mL), followed by high reducing power (428-472 mgAA/g.DE) and inhibition of XOD (IC500.308-0.6261mg/mL). Antimutagenic activity was evaluated in reverse mutation assays with Escherichia coliWP2 oxyR mutant IC202 and deficient in the induction of antioxidant enzymes. The myrtle extracts strongly inhibited mutagenesis induced by t-BOOH, reaching 70% at the highest concentration applied. Antimicrobial activity was examined on eight different bacterial strains. Gram-positive bacteria, S. epidermis, S. aureusand M. flavus demonstrated the highest sensitivity towards extracts (MICs 4.5-9 mg/mL), but significantly lower towards essential oil (MIC 0.42-3.32 mg/mL).","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development, characterization and anti-Mycobacterium tuberculosisactivity of solid lipid nanoparticles for oral Piper corcovadensisroots extract delivery 口服胡椒根提取物固体脂质纳米颗粒的研制、表征和抗结核分枝杆菌活性

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-11-30 DOI: 10.37360/blacpma.23.22.6.55

Carla María Mariano Fernandez, Sirlene Adriana Kleinubing, T. K. Karam, F. Lorenzetti, C. T. Palomo, Byanca Pereira Moreira de Oliveira, Odinei Hess Gonçalves, Zilda Cristiani Gazim, Mariza Barion Romagnolo, K. R. Caleffi-Ferracioli, Regiane Bertin de Lima Scodro, Marli Miriam de Souza Lima, T. U. Nakamura, C. V. Nakamura, B. P. D. Filho

{"title":"Development, characterization and anti-Mycobacterium tuberculosisactivity of solid lipid nanoparticles for oral Piper corcovadensisroots extract delivery","authors":"Carla María Mariano Fernandez, Sirlene Adriana Kleinubing, T. K. Karam, F. Lorenzetti, C. T. Palomo, Byanca Pereira Moreira de Oliveira, Odinei Hess Gonçalves, Zilda Cristiani Gazim, Mariza Barion Romagnolo, K. R. Caleffi-Ferracioli, Regiane Bertin de Lima Scodro, Marli Miriam de Souza Lima, T. U. Nakamura, C. V. Nakamura, B. P. D. Filho","doi":"10.37360/blacpma.23.22.6.55","DOIUrl":"https://doi.org/10.37360/blacpma.23.22.6.55","url":null,"abstract":"The present study thus aimed at the development and physicochemical characterization of solid lipid nanoparticles loaded with crude extract of Piper corcovadensisroots (SLN-CEPc) and chitosan-coated solid lipid nanoparticles loaded withcrude extract of P. corcovadensisroots (C-SLN-CEPc), as well as the determination of its antimycobacterial activity against Mycobacterium tuberculosisH37Rv, its cytotoxicity against the Vero cell line and evaluation in the hemolysis assay. Both formulations containing the encapsulated extract showed high encapsulation efficiency, formed by a monodispersed system with small and spherical particles, and there was no aggregation of particles. In the biological assays, SLN-CEPc and C-SLN-CEPc showed promising anti-M. tuberculosisactivity with a minimum inhibitory concentration (MIC) of 12.5 μg/mL, whereas the cytotoxic concentrations obtained at 50% (CC50) in Vero cells were 60.0 and 70.0 μg/mL, respectively. Therefore, nanoencapsulation showed satisfactory results, justifying its usage in the development of new products.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79895581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-proliferative and anti-inflammatory activity of triterpene extracts from plant species belonging to Lamiaceae family 兰科植物三萜提取物的抗增殖和抗炎活性

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-11-30 DOI: 10.37360/blacpma.23.22.6.58

Nadir Jordamovc, B. Pehlivanovic, H. Niksic, Irma Gusic, Emina Koric, M. Dedić, Belma Tuna-Repovac, F. Becic, K. Duric

{"title":"Anti-proliferative and anti-inflammatory activity of triterpene extracts from plant species belonging to Lamiaceae family","authors":"Nadir Jordamovc, B. Pehlivanovic, H. Niksic, Irma Gusic, Emina Koric, M. Dedić, Belma Tuna-Repovac, F. Becic, K. Duric","doi":"10.37360/blacpma.23.22.6.58","DOIUrl":"https://doi.org/10.37360/blacpma.23.22.6.58","url":null,"abstract":"Triterpenes are very important secondary metabolites with wide structural diversity and significant role in pharmacy and medicine.In the present research, a comparative study of pharamacological activities of the triterpene fractions obtained from several plant species belonging to Lamiaceae family, was carried out. In-vitro anti-proliferative activity was performed using a standardproliferation assay based on tetrazolium salts. In vitro anti-inflammatory activity of triterpene fractions was determined by an assay of inhibition of albumin denaturation. In general, the triterpene fractions obtained from plant species belonging to Lamiaceae family showed a strong anti-proliferative activity and anti-inflammatory activity.The triterpene fraction of Rosmarini folium showed the strongest anti-proliferative activity (GI50range from 4 to 37 μg/ml) and the strongest anti-inflammatory activity in the range from 57.27% to 80.69%. This comparative study provides scientific evidence to support the traditional use of Lamiacae plant species for medical purposes as anti-inflammatory and anti-proliferative medicines.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74723569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Essential oil of Cordia curassavica(Jacq) Roem. & Schult: in vitroand in silicoevaluation of effects on dengue virus replication and cytokines production 芫荽精油。体外和硅片对登革病毒复制和细胞因子产生影响的评价

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-11-30 DOI: 10.37360/blacpma.23.22.6.57

Sindi Alejandra Velandia, Elizabeth Quintero Rueda, Paola Rondon-Villarreal, Lina Marcela Silva, Elena E. Stashenko, Raquel E. Ocazionez

{"title":"Essential oil of Cordia curassavica(Jacq) Roem. & Schult: in vitroand in silicoevaluation of effects on dengue virus replication and cytokines production","authors":"Sindi Alejandra Velandia, Elizabeth Quintero Rueda, Paola Rondon-Villarreal, Lina Marcela Silva, Elena E. Stashenko, Raquel E. Ocazionez","doi":"10.37360/blacpma.23.22.6.57","DOIUrl":"https://doi.org/10.37360/blacpma.23.22.6.57","url":null,"abstract":"The lack of effective conventional therapies against dengue has created an interest in herbal preparations as alternative therapies. In the present study, in vitroeffects of Cordia curassavicaessential oil (EO) on both dengue virus replication and cytokine production were examined. Predictions ofmolecular interactions between EO compounds and virus and cell proteins were performed with AutoDock Vina. The EO inhibited replication of dengue virus serotypes at IC50< 30 μg/mL, and it reduced 87% TNF-α, 67% IL-8 and 46% IFN-α in LPS-stimulated PBMCs.The main EO compounds were trans-β-caryophyllene (21.4%), germacrene D (17.8%), α-copaene (16.5%), trans-β-guaiene (8.2%), and α-pinene (6.0%). The first two compounds, δ-cadinene, α-muurolene, α-cubebene and β-burbonene were coupled to proteins involved in the TLR-4 cytokine effector pathway. 3,7-Guaiadiene was coupled to the viral E and C proteins. This study demonstrates the potential of C. curassavicaEO as a starting point for discovering novel therapeutic for dengue.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77844433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Larrea divaricataa native Argentine plant with potential activity against SARS-CoV-2? 对SARS-CoV-2具有潜在活性的阿根廷本土植物?

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-11-30 DOI: 10.37360/blacpma.23.22.6.52

M. R. Alonso, Carla Marrassini, Malen Saint Martin, Laura Cogoi, Ignacio Peralta, Claudia Anedini

引用次数: 0

Effects of cinnamon oil and its main constituents, cinnamic acid and cinnamaldehyde, on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in PC-12 cells 肉桂油及其主要成分肉桂酸和肉桂醛对1-甲基-4-苯基-1,2,3,6-四氢吡啶诱导的PC-12细胞神经变性的影响

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-11-30 DOI: 10.37360/blacpma.23.22.6.56

Roodabeh Bahramsoltani, Zahra Shahpiri, M. Farzaei, Leila Hosseinzadeh, Davood Rezazadeh, M. Pourfarzam, R. Rahimi

{"title":"Effects of cinnamon oil and its main constituents, cinnamic acid and cinnamaldehyde, on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in PC-12 cells","authors":"Roodabeh Bahramsoltani, Zahra Shahpiri, M. Farzaei, Leila Hosseinzadeh, Davood Rezazadeh, M. Pourfarzam, R. Rahimi","doi":"10.37360/blacpma.23.22.6.56","DOIUrl":"https://doi.org/10.37360/blacpma.23.22.6.56","url":null,"abstract":"Cinnamon (Cinnamomum verumJ.Presl) is a well-known medicinal plant considered as an effective treatment for neurological disorders based on Persian medicine. The aim of the present study was assessing the effect of cinnamon oil, cinnamic acid, and cinnamaldehyde, on the in vitromodel of Parkinson's disease (PD). Cinnamon oil, prepared in sesame oil, was phytochemically analyzed using high performance liquid chromatography (HPLC). Pheochromocytoma-12 (PC-12) cells were treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) as an in vitromodel of neurodegeneration in PD. Cell viability, activity of caspase enzymes, and formation of reactive oxygen species (ROS) were evaluated. MPTP significantly decreased cell viability and increased Casp activity, as well asROS formation. Cinnamon oil and cinnamic acid at 200 μg/mLcould significantly reverse MPTP-induced abnormalities in PC-12 cells including Casp activity and ROS formation. Our study supports the beneficial effect of cinnamon oil in neurodegeneration. Further investigations are needed to clarify the mechanisms and main active components.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81353994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medicinal plants for digestive disorders: Areview of ethnobotanical studies conducted in southern Brazil 消化系统疾病的药用植物:巴西南部民族植物学研究综述

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-11-30 DOI: 10.37360/blacpma.23.22.6.53

Daniela M Gonzalez, M. Ritter, E. Konrath

引用次数: 0

Evaluation of the acute toxicity and antidiabetic activity of Coutoubea spicata “nicolau” ethanolic extract and ethyl acetate fraction 皮皮草乙醇提取物和乙酸乙酯部位的急性毒性及降糖活性评价

IF 0.7 4区医学

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-09-30 DOI: 10.37360/blacpma.23.22.5.44

Jymmys Lopes dos Santos, A. M. O. E. Silva, Lúcio Marques Vieira Souza, Raquel Oliveira Pereira, C. A. Lima, L. Abreu, M. Montalvao, C. B. Correa, T. K. Rabelo, M. C. Duarte, F. Aidar, J. Tavares, C. Estevam, A. C. Marçal

{"title":"Evaluation of the acute toxicity and antidiabetic activity of Coutoubea spicata “nicolau” ethanolic extract and ethyl acetate fraction","authors":"Jymmys Lopes dos Santos, A. M. O. E. Silva, Lúcio Marques Vieira Souza, Raquel Oliveira Pereira, C. A. Lima, L. Abreu, M. Montalvao, C. B. Correa, T. K. Rabelo, M. C. Duarte, F. Aidar, J. Tavares, C. Estevam, A. C. Marçal","doi":"10.37360/blacpma.23.22.5.44","DOIUrl":"https://doi.org/10.37360/blacpma.23.22.5.44","url":null,"abstract":"In order to understand antidiabetic potential and toxicity, this study aimed to evaluate the acute toxicity and antidiabetic activity of ethanolic extract and ethyl acetate fraction obtained from Coutoubea spicata “nicolau” shoots. Chemical constituents and acute toxicity were investigated. In alloxan-induced diabetic rats, extract and fraction were tested at dose of 100 mg/kg, p.o. Body weight gain, glucose, lipid profile and oxidative stress markers in serum and tissues were determined. In vitroantioxidant activity was performed. Swertiamarin, gentiopicrin, deoxyloganic acid, clovin and robinin, and their p-coumaric ester were identified. Extract and fraction were classified as safe (category 5). In diabetic rats, Coutoubea spicata reduced glycaemia, which was accompanied by body weight recovery gain and attenuation in oxidative stress markers. Fraction showed scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH), and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) radical (ABTS) radicals and reducing power higher than that of the extract. Extract and fraction of Coutoubea spicata didn’t present significant toxicity and it can be investigated as a therapeutic alternative in diabetes.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75441294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11