对SARS-CoV-2具有潜在活性的阿根廷本土植物?

IF 0.7 4区医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2023-11-30 DOI:10.37360/blacpma.23.22.6.52

M. R. Alonso, Carla Marrassini, Malen Saint Martin, Laura Cogoi, Ignacio Peralta, Claudia Anedini

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引用次数: 0

摘要

Larrea divaricataCav。是一种南美本土植物，广泛用于炎症和感染性疾病，具有抗炎、免疫调节、抗菌和抗氧化活性。Covid-19是由严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)引起的感染。这种病毒可引起肺炎，甚至在大约5%的病例中导致死亡。本文的目的是通过文献综述证明，L. divaricata具有足够的属性来检测SARS-CoV-2。为此，考虑了化学成分、报告的活性和对接研究。本综述表明，植物提取物具有抑制真菌、细菌和病毒增殖的能力，并在不同的“体外”和“体内”模型中发挥抗炎和免疫调节作用。这些结果表明，该植物是预防和/或治疗SARS -CoV-2的良好候选植物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Larrea divaricataa native Argentine plant with potential activity against SARS-CoV-2?

Larrea divaricataCav. is an autochthonous South American plant popularly used in inflammatory and infectious diseases with reported anti-inflammatory, immunomodulatory, antimicrobial and antioxidant activities. Covid-19 is an infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus can cause pneumonia and even death in about 5% of the cases. The objective of the article was to demonstrate, through a literature review, that L. divaricatahas sufficient attributes to be assayed against SARS-CoV-2. For this, the chemical composition, reported activities and docking studies were taken into account. This review demonstrated that the plant extracts are capable of inhibiting the proliferation of fungi, bacteria and viruses and that they exert anti-inflammatory and immunomodulatory actions in different "in vitro" and "in vivo" models. These results suggest that the plant is a good candidate to be studied for the prevention and/or treatment of SARS -CoV-2.

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来源期刊

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas PHARMACOLOGY & PHARMACY-

CiteScore

1.30

自引率

14.30%

发文量

审稿时长

6-12 weeks

期刊介绍： The Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas (BLACPMA), [Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants]; currently edited by the publishing house MS-Editions, is a bi-monthly international publication that publishes original peerreviewed research in the field of medicinal and aromatic plants, with nearly 20 years of experience. BLACPMA is a scientific journal that publishes two types of articles: Reviews (only in English) and Original Articles (Spanish or English), its main lines of action being agronomy, anthropology and ethnobotany, industrial applications, botany, quality and standardization, ecology and biodiversity, pharmacology, phytochemistry, pharmacognosy, regulatory and legislative aspects. While all areas of medicinal plants are welcome and the experimental approaches used can be broad and interdisciplinary; other areas of research that are not mentioned depend on the Editorial Committee for their acceptance.