Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas最新文献

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Smoke of Capsicum baccatumL. var. baccatum (Solanaceae) repels nymphs of Triatoma infestans(Klug) (Hemiptera: Reduviidae) 辣椒烟。百合花(茄科)可驱蚊(半翅目:百合花科)
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.2.13
Jhean-Carla Echalar, R. Cossio-Rodriguez, D. Véliz, Fabricio Cardozo-Alarcon, H. Niemeyer, C. F. Pinto
{"title":"Smoke of Capsicum baccatumL. var. baccatum (Solanaceae) repels nymphs of Triatoma infestans(Klug) (Hemiptera: Reduviidae)","authors":"Jhean-Carla Echalar, R. Cossio-Rodriguez, D. Véliz, Fabricio Cardozo-Alarcon, H. Niemeyer, C. F. Pinto","doi":"10.37360/blacpma.22.21.2.13","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.2.13","url":null,"abstract":"Control of the Chagas disease vector, Triatoma infestans(Klug) (Hemiptera: Reduviidae) with synthetic pesticides in Bolivia has become increasingly inefficient due to the development of resistance in the insects. In the Chaco region of Bolivia, guaraní populations have approached the problem by fumigating their houses with the smoke of native plants. Through interviews and field work with local guides, the main plant used by the guaraníes was collected and later identified as Capsicum baccatumL. var. baccatum(Solanaceae). In choice bioassays, filter papers exposed to the smoke of the plant repelled nymphs of T. infestans. Activity remained significant after storing the exposed filter papers for 9 days. Chemical analysis of smoke and literature data suggested that capsaicinoids present in the smoke were responsible for the repellent effect. The data presented provide a rationale for the use of C. baccatumvar. baccatumto control the Chagas vector bythe guaraní populations.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"8 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82410708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Seasonal variance in the chemical composition of essential oils from Lantana camaraaccessions and their trypanocidal activity on Phytomonas serpens 山楂挥发油化学成分的季节变化及其对蛇单胞菌的杀锥虫活性
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.6.45
K. L. G. Pereira, D. A. C. Nizio, Paulo Cesar Nogueira de Lima, R. P. Fernandes, M. F. Arrigoni-Blank, Jose Carlos Freitas de Sá Filho, L. F. A. Nascimento, Vinicius Trindade de Souza, K. P. Silva, A. Blank
{"title":"Seasonal variance in the chemical composition of essential oils from Lantana camaraaccessions and their trypanocidal activity on Phytomonas serpens","authors":"K. L. G. Pereira, D. A. C. Nizio, Paulo Cesar Nogueira de Lima, R. P. Fernandes, M. F. Arrigoni-Blank, Jose Carlos Freitas de Sá Filho, L. F. A. Nascimento, Vinicius Trindade de Souza, K. P. Silva, A. Blank","doi":"10.37360/blacpma.22.21.6.45","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.6.45","url":null,"abstract":"The objective of this study was to investigate the seasonal variance of the content and chemical composition of the essential oil from Lantana camaraaccessions at two harvest times, and to analyze the trypanocidal activity on Phytomonas serpens. Essential oil content ranged from 0.13 to 0.29% in the rainy season and from 0.13 to 0.33% in the dryseason. The compounds E-caryophyllene, α-humulene, α-curcumene and germacrene D defined the formation of four chemical clusters in the rainy and dry seasons, classified as: Cluster 1 (E-caryophyllene + germacrene D); Cluster 2 (germacrene D + E-caryophyllene); Cluster 3 (α-humulene + E-caryophyllene); and Cluster 4 (α-curcumene + E-caryophyllene). All L. camaraessential oils, representing the four chemical clusters, inhibited P. serpenswith low concentrations, considering the following IC50values: 18.34±6.60 μg/mL (LAC-018, Cluster 1); 9.14±3.87 μg/mL (LAC-027, Cluster 2); 14.56±3.40 μg/mL (LAC-037, Cluster 3); and 14.97±2.68 μg/mL (LAC-019, Cluster 4).","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"90 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90509398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Change in leaf anatomy, physiology, and essential oil of Varronia curassavica Jacq. accessions under two light conditions 花蔷薇叶解剖、生理及精油的变化。在两个轻条件下的加入
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.6.47
M. F. Arrigoni-Blank, Jefferson Henrique Santos Silva, I. B. Gois, E. D. de Castro, A. Blank, D. A. C. Nizio, P. Nogueira, T. S. A. Menezes-Sá
{"title":"Change in leaf anatomy, physiology, and essential oil of Varronia curassavica Jacq. accessions under two light conditions","authors":"M. F. Arrigoni-Blank, Jefferson Henrique Santos Silva, I. B. Gois, E. D. de Castro, A. Blank, D. A. C. Nizio, P. Nogueira, T. S. A. Menezes-Sá","doi":"10.37360/blacpma.22.21.6.47","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.6.47","url":null,"abstract":"The aim of this study was to evaluate the effect of light on anatomy, physiology and essential oil content and composition of Varronia curassavica. They were analysed two light conditions (full sunlight and protected environment with 50% shade screen) and five accessions (VCUR-101, VCUR-102, VCUR-201, VCUR-302, VCUR-802). V. curassavicacultivated in full sun presented a greater development of the leaf blade and palisade parenchyma thickness for all accessions. Chlorophyll levels did not differ according to the two light environments. The leaf area was larger in the protected environment. The essential oil yield of the accessions ranged from 0.26 to 0.87 mL/plant in full sun and from 0.34 to 0.53 mL/plant in the protected environment. The composition of the essential oil was influenced by the light and the accession. All accessions presented (E)-caryophyllene and α-humulene. The influence of light on the evaluated variables is genotype dependent.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"24 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90325413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inter and intra population phenotypic variability of Lippia integrifolia(Verbenaceae) and its natural situation in the west-center of Argentina 阿根廷中西部地区马鞭草科植物群间和群内表型变异及其自然状况
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.2.15
P. Brunetti, Romina Leiva, R. Zapata, L. E. Torres, A. G. Chaves, H. Juliani, M. Ojeda
{"title":"Inter and intra population phenotypic variability of Lippia integrifolia(Verbenaceae) and its natural situation in the west-center of Argentina","authors":"P. Brunetti, Romina Leiva, R. Zapata, L. E. Torres, A. G. Chaves, H. Juliani, M. Ojeda","doi":"10.37360/blacpma.22.21.2.15","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.2.15","url":null,"abstract":"The species Lippia integrifoliais an aromatic, sub-woody shrub, distributed from Northwest and Central Argentina to Bolivia. It is among the most important native aromatic species. It presents medicinal properties, some of which have been scientifically proven. As an alternative to harvesting, the process of domestication of the species was initiated. The objective of this work was to assess the phenotypic variability based on botanical-taxonomic and morpho-agronomic descriptors and the use of indicators to evaluate its natural situation in the west-center of Argentina. We worked in five wild populations, registering morphological variables, phenology, natural regeneration, herbivory and presence of diseases. L. integrifoliapresents a wide morphological variability, which can be explained with three morphological descriptors. Natural regeneration ́s rate is very low to zero, in four of the sites. The results obtained are of importance to make decisions related to the sustainable use in situ, and to begin a program of domestication of the species.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"16 4 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75472709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
n situcharacterization of populations of Aloysia gratissimavar. gratissimacollected from the northeast of the province of San Luis, Argentina n野菜居群的生境特征。从阿根廷圣路易斯省东北部收集的gratissima
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.4.26
Orcar A Risso, A. Posadaz, M. Leal, C. Ardanaz, S. A. Suarez, M. Ojeda
{"title":"n situcharacterization of populations of Aloysia gratissimavar. gratissimacollected from the northeast of the province of San Luis, Argentina","authors":"Orcar A Risso, A. Posadaz, M. Leal, C. Ardanaz, S. A. Suarez, M. Ojeda","doi":"10.37360/blacpma.22.21.4.26","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.4.26","url":null,"abstract":"The aerial part of Aloysia gratissima(Gillies & Hook. ex Hook.) Tronc., \"Usillo\", is used as aromatic and medicinal. It is a shrub of up to 3 meters, distributed in North America, from the south of the USA to the north of Mexico, and in South America up to the 37th parallel. As in other native species, the demand is covered by harvesting in wild populations, which brings about the deterioration of the resource and lack of homogeneity of the harvested product. The variability was characterized in nine populations of A. gratissimavar. gratissima from the northeast of San Luis, Argentina, based on morphological and phytochemical characters. It was found that the species in the region presents considerable heterogeneity. Diversity was detected in the chemical characteristics of the essential oils analyzed and the prevalence of mono and sesquiterpenes was related to the olfactory identities identified. The main components were the sesquiterpene spatulenol and the monoterpene 1,8 cineole.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"36 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79806204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Extract of Glycyrrhiza glabraroot attenuates nociception in experimental pain models: The role of BKCa channels 甘草提取物减轻实验性疼痛模型中的伤害感受:BKCa通道的作用
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.4.29
A. Parlar, Rabia Edibe Parlar Koprulu, S. Arslan, S. Cam, Fidan Pesen Ozdogan, O. Yumrutas, F. Uckardes, Miguel Rios, Jose L. Martinez
{"title":"Extract of Glycyrrhiza glabraroot attenuates nociception in experimental pain models: The role of BKCa channels","authors":"A. Parlar, Rabia Edibe Parlar Koprulu, S. Arslan, S. Cam, Fidan Pesen Ozdogan, O. Yumrutas, F. Uckardes, Miguel Rios, Jose L. Martinez","doi":"10.37360/blacpma.22.21.4.29","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.4.29","url":null,"abstract":"The aim of this study was to evaluate the functional interaction of Glycyrrhiza glabraroot extract (GGRE) on the large conductance Ca2+-activated K+(BKCa) channels expressed in the peripheral nervous system by using nociception and inflammation models in rodents in vivo. Besides toxicity studies and open field tests, nociception and inflammation tests were performed on rodents. Different doses of GGRE were given orally to rats and mice. Naloxone, indomethacin, morphine, NS1619 and iberiotoxin (IbTX) were administered. GGRE had both anti-nociceptive and anti-inflammatory activity in rats and mice. GGRE exhibited an analgesic effect by decreasing the time-course of the pain threshold or reaction time insome nociceptive tests. Furthermore, GGRE reduced level of pro-inflammatory cytokines, including TNF-α and IL-1β. As a conclusion, GGRE can alleviate the pain sensation of the afferent nerves and can reduce inflammation and associated pain by activating BKCa channels and reducing the levels of TNF-α, IL1β.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"102 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88996150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Plants and intestinal parasitosis: a review on ethnopharmacological use by the Kantaruré-Batida indigenous community of Brazil 植物与肠道寄生虫病:巴西kantarur<s:1> - batida土著社区的民族药物学研究综述
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.3.17
Dayvison Rhuan Vasco-dos-Santos, Jessica Vieira dos Santos, María José Gomes de Andrade, Lidiane Nunes Lima, Wbaneide Martins de Andrade, E. S. Nunes, A. Dias-Lima, M. Vannier-Santos
{"title":"Plants and intestinal parasitosis: a review on ethnopharmacological use by the Kantaruré-Batida indigenous community of Brazil","authors":"Dayvison Rhuan Vasco-dos-Santos, Jessica Vieira dos Santos, María José Gomes de Andrade, Lidiane Nunes Lima, Wbaneide Martins de Andrade, E. S. Nunes, A. Dias-Lima, M. Vannier-Santos","doi":"10.37360/blacpma.22.21.3.17","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.3.17","url":null,"abstract":"Indigenous knowledge is one of the most notable traditional sources about plants used to treat diseases. Thus, the aim of this study was to describe the botanical features and to investigate the pharmacological properties of plants used by the Kantaruré-Batida community to treat intestinal parasitosis. Botanical characterization was performed based on integrative review and on access to ‘Flora do Brasil’ platform, whereas plants’ pharmacological properties were investigated through systematic review. Among the 21 ethnospecies used, 48% were described as having activity against intestinal parasites. Although 52% had no such activity described, other properties can account for their use, that indicates that further studies are required. Therefore, this review reinforces the importance of valuing indigenous knowledge as tool to guide antiparasitic agent trials.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"46 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90773973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethnobotanical knowledge of herbalists about medicinal plants from the semiarid region in northeastern Brazil 中草药医师对巴西东北部半干旱地区药用植物的民族植物学知识
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.6.49
Ernani Canuto Figueirêdo Júnior, Bruna Palmeira Costa, Julliana Cariry Palhano Freire, Walaska Ohana de Souza Melo, L. C. D. de Lima, M. A. Xavier, Helena Aguiar Ribeiro do Nascimento, Patricia Vidal de Negreiros Nobrega, D. Gomes, J. Pereira
{"title":"Ethnobotanical knowledge of herbalists about medicinal plants from the semiarid region in northeastern Brazil","authors":"Ernani Canuto Figueirêdo Júnior, Bruna Palmeira Costa, Julliana Cariry Palhano Freire, Walaska Ohana de Souza Melo, L. C. D. de Lima, M. A. Xavier, Helena Aguiar Ribeiro do Nascimento, Patricia Vidal de Negreiros Nobrega, D. Gomes, J. Pereira","doi":"10.37360/blacpma.22.21.6.49","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.6.49","url":null,"abstract":"Medicinal plants have been used since ancient times to treat illnesses. This study aimed to identify through questionnaire the medicinal plants most frequently sold on public and street markets in some municipalities of Paraíba state, northeastern Brazil, and the knowledge of herbalists about their therapeutic indications and forms of use. The sample consisted of 28 herbalists. Fifteen plants with a dental indication were identified, including barbatimão (Stryphnodendron adstringens), aroeira (Myracrodruon urundeuva), gengibre (Zingiber officinale), romã (Punica granatum), cajueiro-roxo (Anacardium occidentale), mulungu (Erythrina velutina) andquixaba (Sideroxylon obtusfolium), as well as 21 plants used for the treatment of general diseases, including barbatimão (S. adstringens), aroeira (M. urundeuva), cajueiro-roxo (A. occidentale), quixaba (S. obtusfolium), boldo (Peumus boldus) and erva doce (Pimpinella anisum). Bottled preparations (\"garrafadas\")and teas were the most frequently indicated forms of use. The results suggest that herbalists have a vast traditional knowledge of the therapeutic potential of commercialized plants.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"9 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77633719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Bacopa monnieri: Historical aspects to promising pharmacological actions for the treatment of central nervous system diseases 假马齿苋:治疗中枢神经系统疾病药理作用的历史研究
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.2.09
Andreia F. M. Santos, Marília Moraes Queiroz Souza, K. Pauli, Gustavo Ratti da Silva, Midia Wolff Marques, P. A. Auth, W. Bortolucci, Z. C. Gazim, G. Linde, N. Colauto, E. C. W. Lovato, F. Lívero
{"title":"Bacopa monnieri: Historical aspects to promising pharmacological actions for the treatment of central nervous system diseases","authors":"Andreia F. M. Santos, Marília Moraes Queiroz Souza, K. Pauli, Gustavo Ratti da Silva, Midia Wolff Marques, P. A. Auth, W. Bortolucci, Z. C. Gazim, G. Linde, N. Colauto, E. C. W. Lovato, F. Lívero","doi":"10.37360/blacpma.22.21.2.09","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.2.09","url":null,"abstract":"Bacopa monnieri(L.) Wettst. (Plantaginaceae), also known as Brahmi, has been used to improve cognitive processes and intellectual functions that are related to the preservation of memory. The objective of this research is to review the ethnobotanical applications, phytochemical composition, toxicity and activity of B. monnieriin the central nervous system. It reviewed articles on B. monnieriusing Google Scholar, SciELO, Science Direct, Lilacs, Medline, and PubMed. Saponins are the main compounds in extracts of B. monnieri. Pharmacological studies showed that B. monnieriimproves learning and memory and presents biological effects against Alzheimer’s disease, Parkinson’s disease, epilepsy, and schizophrenia. No preclinical acute toxicity was reported. However, gastrointestinal side effects were reported in some healthy elderly individuals. Most studies with B. monnierihave been preclinical evaluations of cellular mechanisms in the central nervous system and further translational clinical research needs to be performed to evaluate the safety and efficacy of the plant.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"2004 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89523436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytotoxic effect of hydroalcoholic extract of Cota tinctoria (L.) J.Gay on AGS and Hep-G2 cancer cell lines 花楸水醇提取物的细胞毒作用J.Gay对AGS和Hep-G2癌细胞系的研究
IF 0.7 4区 医学
Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas Pub Date : 2022-01-01 DOI: 10.37360/blacpma.22.21.1.07
Sharareh Shamloo, Sayeh Jafari Marandi, G. Tajadod, A. Majd, R. Rahimi
{"title":"Cytotoxic effect of hydroalcoholic extract of Cota tinctoria (L.) J.Gay on AGS and Hep-G2 cancer cell lines","authors":"Sharareh Shamloo, Sayeh Jafari Marandi, G. Tajadod, A. Majd, R. Rahimi","doi":"10.37360/blacpma.22.21.1.07","DOIUrl":"https://doi.org/10.37360/blacpma.22.21.1.07","url":null,"abstract":"Cota tinctoria is a medicinal plant which has been used for management of cancer in folk medicine of various regions. The aim of present study is to investigate cytotoxic activity of different concentrations of hydroalcoholic extract of C. tinctoria flowers on gastric (AGS) and liver (Hep-G2) cancer cell lines as well as Human Natural GUM fibroblast (HUGU) cells. Cell mortality rates were examined after 24, 48 and 72 h incubations using the MTT assay. IC50 of extract on AGS cells after 24, 48 and 72h was 1.46, 1.29 and 1.14 µg/mL respectively. The extract demonstrated IC50 of 5.15, 3.92 and 2.89 µg/mL on Hep-G2 cells after 24, 48 and 72 h respectively. No cytotoxic effect was detected on HUGU (Human Natural GUM fibroblast) cells. C. tinctoria seems to have a promising potential to be considered as a source for anticancer drug discovery. However, more experimental and clinical studies are required.","PeriodicalId":55342,"journal":{"name":"Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas","volume":"2 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85414144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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