Brain and Cognition最新文献_第9页

Music training affects listeners’ processing of different types of accentuation information: Evidence from ERPs 音乐训练影响听者对不同类型重音信息的处理：来自 ERP 的证据

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-12-23 DOI: 10.1016/j.bandc.2023.106120

Mei Han , Yu-Fu Chien , Zhenghua Zhang , Zhen Wei , Weijun Li

{"title":"Music training affects listeners’ processing of different types of accentuation information: Evidence from ERPs","authors":"Mei Han , Yu-Fu Chien , Zhenghua Zhang , Zhen Wei , Weijun Li","doi":"10.1016/j.bandc.2023.106120","DOIUrl":"10.1016/j.bandc.2023.106120","url":null,"abstract":"<div><p>Previous studies found that prolonged musical training can promote language processing, but few studies have examined whether and how musical training affects the processing of accentuation in spoken language. In this study, a vocabulary detection task was conducted, with Chinese single sentences as materials, to investigate how musicians and non-musicians process corrective accent and information accent in the sentence-middle and sentence-final positions. In the sentence-middle position, results of the cluster-based permutation t-tests showed significant differences in the 574–714 ms time window for the control group. In the sentence-final position, the cluster-based permutation t-tests revealed significant differences in the 612–810 ms time window for the music group and in the 616–812 ms time window for the control group. These significant positive effects were induced by the processing of information accent relative to that of corrective accent. These results suggest that both groups were able to distinguish corrective accent from information accent, but they processed the two accent types differently in the sentence-middle position. These findings show that musical training has a cross-domain effect on spoken language processing and that the accent position also affects its processing.</p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"174 ","pages":"Article 106120"},"PeriodicalIF":2.5,"publicationDate":"2023-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139032904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A spontaneous dissociative episode during an EEG experiment 脑电图实验中的自发分离事件

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-12-23 DOI: 10.1016/j.bandc.2023.106121

Graham Jamieson , Etzel Cardeña , Vilfredo de Pascalis

{"title":"A spontaneous dissociative episode during an EEG experiment","authors":"Graham Jamieson , Etzel Cardeña , Vilfredo de Pascalis","doi":"10.1016/j.bandc.2023.106121","DOIUrl":"10.1016/j.bandc.2023.106121","url":null,"abstract":"<div><p>A depersonalization episode occurred unexpectedly during an electroencephalogram (EEG) recording for a study. Experience reports tracked the time course of this event and, in conjunction, with EEG data, were analyzed. The source activity across canonical frequency bands was analyzed across four periods ended by retrospective experience reports (depersonalization was reported in the 2nd period). Delta and theta decreases occurred across all time periods with no relation to reported events. Theta and alpha increases occurred in right secondary visual areas following depersonalization, which also coincided with surges in beta and gamma. The largest increases occurred in bilateral fronto-polar and medial prefrontal cortex, followed by inferior left lateral fronto-insula-temporal cortices and right secondary visual cortex. A high frequency functional network with a principal hub in left insula closely overlapped inferior left cortical gamma band-power increases. Bilateral frontal increases in gamma are consistent with studies of dissociation. We interpret gamma and later beta, alpha, and theta band increases as arising from the generation of visual priors, in the absence of precise visual signals, which constrain interoceptive and proprioceptive predictions to reestablish a stable sense of physiological-self. Beta showed local increases following the pattern of gamma but showed no changes in functional connectivity.</p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"174 ","pages":"Article 106121"},"PeriodicalIF":2.5,"publicationDate":"2023-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S027826262300180X/pdfft?md5=62092578175a7dac4559b358536253f6&pid=1-s2.0-S027826262300180X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139027923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of the cognitive section of the Penn computerized adaptive test for neurocognitive and clinical psychopathology assessment (CAT-CCNB) 宾夕法尼亚大学神经认知和临床心理病理学评估计算机适应性测试（CAT-CNB）认知部分的验证

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-12-20 DOI: 10.1016/j.bandc.2023.106117

Akira Di Sandro , Tyler M. Moore , Eirini Zoupou , Kelly P. Kennedy , Katherine C. Lopez , Kosha Ruparel , Lucky J. Njokweni , Sage Rush , Tarlan Daryoush , Olivia Franco , Alesandra Gorgone , Andrew Savino , Paige Didier , Daniel H. Wolf , Monica E. Calkins , J. Cobb Scott , Raquel E. Gur , Ruben C. Gur

{"title":"Validation of the cognitive section of the Penn computerized adaptive test for neurocognitive and clinical psychopathology assessment (CAT-CCNB)","authors":"Akira Di Sandro , Tyler M. Moore , Eirini Zoupou , Kelly P. Kennedy , Katherine C. Lopez , Kosha Ruparel , Lucky J. Njokweni , Sage Rush , Tarlan Daryoush , Olivia Franco , Alesandra Gorgone , Andrew Savino , Paige Didier , Daniel H. Wolf , Monica E. Calkins , J. Cobb Scott , Raquel E. Gur , Ruben C. Gur","doi":"10.1016/j.bandc.2023.106117","DOIUrl":"https://doi.org/10.1016/j.bandc.2023.106117","url":null,"abstract":"<div><h3>Background</h3><p>The Penn Computerized Neurocognitive Battery is an efficient tool for assessing brain-behavior domains, and its efficiency was augmented via computerized adaptive testing (CAT). This battery requires validation in a separate sample to establish psychometric properties.</p></div><div><h3>Methods</h3><p>In a mixed community/clinical sample of N = 307 18-to-35-year-olds, we tested the relationships of the CAT tests with the full-form tests. We compared discriminability among recruitment groups (psychosis, mood, control) and examined how their scores relate to demographics. CAT-Full relationships were evaluated based on a minimum inter-test correlation of 0.70 <em>or</em> an inter-test correlation within at least 0.10 of the full-form correlation with a previous administration of the full battery. Differences in criterion relationships were tested via mixed models.</p></div><div><h3>Results</h3><p>Most tests (15/17) met the minimum criteria for replacing the full-form with the updated CAT version (mean r = 0.67; range = 0.53–0.80) when compared to relationships of the full-forms with previous administrations of the full-forms (mean r = 0.68; range = 0.50–0.85). Most (16/17) CAT-based relationships with diagnostics and other validity criteria were indistinguishable (interaction p > 0.05) from their full-form counterparts.</p></div><div><h3>Conclusions</h3><p>The updated CNB shows psychometric properties acceptable for research. The full-forms of some tests should be retained due to insufficient time savings to justify the loss in precision.</p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"174 ","pages":"Article 106117"},"PeriodicalIF":2.5,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138821993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical reliance on monocular visual pathway for face and word recognition in developmental dyslexia 发育性阅读障碍患者非典型依赖单眼视觉通路进行面部和文字识别

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-11-28 DOI: 10.1016/j.bandc.2023.106106

Noa Peskin , Marlene Behrmann , Shai Gabay , Yafit Gabay

{"title":"Atypical reliance on monocular visual pathway for face and word recognition in developmental dyslexia","authors":"Noa Peskin , Marlene Behrmann , Shai Gabay , Yafit Gabay","doi":"10.1016/j.bandc.2023.106106","DOIUrl":"https://doi.org/10.1016/j.bandc.2023.106106","url":null,"abstract":"<div><p>Studies with individuals with developmental dyslexia (DD) have documented impaired perception of words and faces, both of which are domains of visual expertise for human adults. In this study, we examined a possible mechanism that might be associated with the impaired acquisition of visual expertise for words and faces in DD, namely, the atypical engagement of the monocular visual pathway. Participants with DD and typical readers (TR) judged whether a pair of sequentially presented unfamiliar faces or nonwords were the same or different, and the pair of stimuli were displayed in an eye-specific fashion using a stereoscope. Based on evidence of greater reliance on subcortical structures early in development, we predicted differences between the groups in the engagement of lower (monocular) versus higher (binocular) regions of the visual pathways. Whereas the TR group showed a monocular advantage for both stimulus types, the DD participants evinced a monocular advantage for faces and words that was much greater than that measured in the TRs. These findings indicate that the DD individuals have enhanced subcortical engagement and that this might arise from the failure to fine-tune cortical correlates mediating the discrimination of homogeneous exemplars in domains of expertise.</p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"174 ","pages":"Article 106106"},"PeriodicalIF":2.5,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138448680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A fist bump in a political meeting? The influence of social context on affordance selection 在政治会议上碰拳?社会语境对可视性选择的影响

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-11-20 DOI: 10.1016/j.bandc.2023.106100

Léna Guézouli , Vincent Roy , Camille Bodoux , Josselin Baumard

{"title":"A fist bump in a political meeting? The influence of social context on affordance selection","authors":"Léna Guézouli , Vincent Roy , Camille Bodoux , Josselin Baumard","doi":"10.1016/j.bandc.2023.106100","DOIUrl":"https://doi.org/10.1016/j.bandc.2023.106100","url":null,"abstract":"<div><p>Historically, understanding human cognition<span> such as action processing has been a challenging issue in cognitive neuropsychology and the more we know about cognition, the more we shape it as a complex, multi-determined phenomenon that is embedded in a social context. The present study aimed at understanding how the social context could influence affordance selection. We hypothesized that affordance selection would be modulated by social context and that a given hand configuration would be considered appropriate or not, as a function of the presence or absence of social context. Twenty-six healthy participants were asked to judge the appropriateness of three variants of 10 hand-object interactions based on photographs presented with or without a visual, social context. In our results, hand configurations were intrinsically acceptable or not, but this effect was modulated by the social context. A three-step model of the influence of social context on affordance selection was proposed, according to which selection depends on social norms, in the form of social knowledge and social context analysis.</span></p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"173 ","pages":"Article 106100"},"PeriodicalIF":2.5,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138136146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of transcranial direct current stimulation and transcranial random noise stimulation on working memory and task-related EEG in major depressive disorder 经颅直流电刺激和经颅随机噪声刺激对重度抑郁症工作记忆和任务相关脑电图的影响

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-11-12 DOI: 10.1016/j.bandc.2023.106105

O.W. Murphy , K.E. Hoy , D. Wong , N.W. Bailey , P.B. Fitzgerald , R.A. Segrave

{"title":"Effects of transcranial direct current stimulation and transcranial random noise stimulation on working memory and task-related EEG in major depressive disorder","authors":"O.W. Murphy , K.E. Hoy , D. Wong , N.W. Bailey , P.B. Fitzgerald , R.A. Segrave","doi":"10.1016/j.bandc.2023.106105","DOIUrl":"https://doi.org/10.1016/j.bandc.2023.106105","url":null,"abstract":"<div><h3>Objective</h3><p>To compare effects of transcranial direct current stimulation (tDCS) and transcranial random noise stimulation with a direct-current offset (tRNS + DC-offset) on working memory (WM) performance and task-related electroencephalography (EEG) in individuals with Major Depressive Disorder (MDD).</p></div><div><h3>Methods</h3><p>Using a sham-controlled, parallel-groups design, 49 participants with MDD received either anodal tDCS (N = 16), high-frequency tRNS + DC-offset (N = 16), or sham stimulation (N = 17) to the left dorsolateral prefrontal cortex (DLPFC) for 20-minutes. The Sternberg WM task was completed with concurrent EEG recording before and at 5- and 25-minutes post-stimulation. Event-related synchronisation/desynchronisation (ERS/ERD) was calculated for theta, upper alpha, and gamma oscillations during WM encoding and maintenance.</p></div><div><h3>Results</h3><p>tDCS significantly increased parieto-occipital upper alpha ERS/ERD during WM maintenance, observed on EEG recorded 5- and 25-minutes post-stimulation. tRNS + DC-offset did not significantly alter WM-related oscillatory activity when compared to sham stimulation. Neither tDCS nor tRNS + DC-offset improved WM performance to a significantly greater degree than sham stimulation.</p></div><div><h3>Conclusions</h3><p>Although tDCS induced persistent effects on WM-related oscillatory activity, neither tDCS nor tRNS + DC-offset enhanced WM performance in MDD.</p></div><div><h3>Significance</h3><p>This reflects the first sham-controlled comparison of tDCS and tRNS + DC-offset in MDD. These findings directly contrast with evidence of tRNS-induced enhancements in WM in healthy individuals.</p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"173 ","pages":"Article 106105"},"PeriodicalIF":2.5,"publicationDate":"2023-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0278262623001641/pdfft?md5=d3f15a2a6c31eb68baecf98f86804216&pid=1-s2.0-S0278262623001641-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92023248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preterm infants show an atypical processing of the mother's voice 早产儿表现出对母亲声音的非典型处理。

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-11-09 DOI: 10.1016/j.bandc.2023.106104

Manuela Filippa , Damien Benis , Alexandra Adam-Darque , Didier Grandjean , Petra S. Hüppi

{"title":"Preterm infants show an atypical processing of the mother's voice","authors":"Manuela Filippa , Damien Benis , Alexandra Adam-Darque , Didier Grandjean , Petra S. Hüppi","doi":"10.1016/j.bandc.2023.106104","DOIUrl":"10.1016/j.bandc.2023.106104","url":null,"abstract":"<div><p>To understand the consequences of prematurity on language perception, it is fundamental to determine how atypical early sensory experience affects brain development. At term equivalent age, ten preterm and ten full-term newborns underwent high-density EEG during mother or stranger speech presentation, in the forward or backward order. A general group effect terms > preterms is evident in the theta frequency band, in the left temporal area, with preterms showing significant activation for strangers’ and terms for the mother’s voice. A significant group contrast in the low and high theta in the right temporal regions indicates higher activations for the stranger's voice in preterms. Finally, only full terms presented a late gamma band increase for the maternal voice, indicating a more mature brain response.</p><p>EEG time–frequency analysis demonstrate that preterm infants are selectively responsive to stranger voices in both temporal hemispheres, and that they lack selective brain responses to their mother’s forward voice.</p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"173 ","pages":"Article 106104"},"PeriodicalIF":2.5,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S027826262300163X/pdfft?md5=5fcd8ddf2946f13521799a39c7f36f47&pid=1-s2.0-S027826262300163X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72212123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The CODECS study: COgnitive DEficits in Cerebellar Stroke CODECS研究：小脑卒中的认知缺陷。

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-11-02 DOI: 10.1016/j.bandc.2023.106102

Ruben S. van der Giessen , Djaina Satoer , Peter J. Koudstaal

{"title":"The CODECS study: COgnitive DEficits in Cerebellar Stroke","authors":"Ruben S. van der Giessen , Djaina Satoer , Peter J. Koudstaal","doi":"10.1016/j.bandc.2023.106102","DOIUrl":"10.1016/j.bandc.2023.106102","url":null,"abstract":"<div><p>Part of the extra-pyramidal system, the cerebellum is more and more recognized by its non-motor functions known as the cerebellar cognitive affective syndrome. Several studies have identified disturbances specifically in executive and attentional functions after focal cerebellar lesions. However, most studies were performed in small and heterogeneous patient groups. Furthermore, there is a substantial variation in the methodology of assessment. Here, we present the results of a large and homogeneous cohort of patients with isolated uniform cerebellar lesions. After three months post-stroke all patients underwent structural neuroimaging to confirm an isolated lesion and were given neuropsychological testing. The results show that cerebellar lesions relate to mild but long-term cognitive impairment in a broad spectrum of neurocognitive functions compared to normative values. These findings confirm involvement of the cerebellum in cognitive processing and supports the theory of ‘dysmetria of thought’ based upon uniform cerebellar processing in multiple cognitive domains. This study highlights the following results: 1-Cognitive impairments after isolated cerebellar stroke is confirmed in several cognitive domains. 2-Semantic and phonemic fluency are most affected in cerebellar stroke patients. 3-Verbal deficits show an age-independent long term effect post-stroke and should be studied further in depth. 4-Cognitive disorders after cerebellar stroke are more prominent in women than men.</p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"173 ","pages":"Article 106102"},"PeriodicalIF":2.5,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0278262623001616/pdfft?md5=420b2afe84162ce51b919ec28e299fd7&pid=1-s2.0-S0278262623001616-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Temporo-Parietal cortex activation during motor imagery in older adults: A case study of Baduanjin 老年人运动想象过程中颞叶顶叶皮层的激活：八段锦的个案研究。

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-11-01 DOI: 10.1016/j.bandc.2023.106103

Xiaoxia Yuan , Xiaoke Zhong , Chen Wang , Yuanfu Dai , Yuan Yang , Changhao Jiang

{"title":"Temporo-Parietal cortex activation during motor imagery in older adults: A case study of Baduanjin","authors":"Xiaoxia Yuan , Xiaoke Zhong , Chen Wang , Yuanfu Dai , Yuan Yang , Changhao Jiang","doi":"10.1016/j.bandc.2023.106103","DOIUrl":"10.1016/j.bandc.2023.106103","url":null,"abstract":"<div><p>Age-associated cognitive and motor decline is related to central nervous system injury in older adults. Motor imagery training (MIT), as an emerging rehabilitative intervention, can activate neural basis similar to that in actual exercise, so as to promote motor function in older adults. The complex motor skills rely on the functional integration of the cerebral cortex. Understanding the neural mechanisms underlying motor imagery in older adults would support its application in motor rehabilitation and slowing cognitive decline. Based on this, the present study used functional near infrared spectroscopy (fNIRS) to record the changes in oxygen saturation in older adults (20 participants; mean age, 64.8 ± 4.5 years) during Baduanjin motor execution (ME) and motor imagery (MI). ME significantly activated the left postcentral gyrus, while the oxy-hemoglobin concentration in the right middle temporal gyrus increased significantly during motor imagery. These results indicate that advanced ME activates brain regions related to sensorimotor function, and MI increases the activation of the frontal-parietal cortex related to vision. In older adults, MI overactivated the temporo-parietal region associated with vision, and tend to be activated in the right brain.</p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"173 ","pages":"Article 106103"},"PeriodicalIF":2.5,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monocular eye patching modulates ipsilesional reactive saccades and smooth pursuit in patients with left hemispatial neglect 单眼眼罩调节左半球忽视患者的同侧反应性跳远和平滑追求

IF 2.5 3区心理学

Brain and Cognition Pub Date : 2023-10-30 DOI: 10.1016/j.bandc.2023.106101

Nadine Schenke , Paul Eling , Thomas Duning , Helmut Hildebrandt

{"title":"Monocular eye patching modulates ipsilesional reactive saccades and smooth pursuit in patients with left hemispatial neglect","authors":"Nadine Schenke , Paul Eling , Thomas Duning , Helmut Hildebrandt","doi":"10.1016/j.bandc.2023.106101","DOIUrl":"https://doi.org/10.1016/j.bandc.2023.106101","url":null,"abstract":"<div><p>Patients with hemispatial neglect show multiple oculomotor deficits like delayed contralesional saccade latencies, hypometric saccade amplitudes, and impaired smooth pursuit. We aimed to investigate whether modulation of superior colliculus (SC) activity via monocular eye patching improves neglect patients’ eye movements to the contralesional side of space. Thirteen neglect patients with left-hemispheric (LH) stroke, 22 neglect patients with right-hemispheric (RH) stroke, and 24 healthy controls completed a video-oculographic examination of horizontal smooth pursuit and reactive saccades twice, while the left or right eye was covered with an eye patch. Independent of the eye patch position, LH and RH patients showed enlarged saccade latencies toward contralesional stimuli. In addition, both during smooth pursuit and reactive saccades, RH patients made significantly fewer rightward saccades when the right than when the left eye was patched. Moreover, during reactive saccades, RH patients made significantly fewer right than left saccades, but only when the right eye was patched. These findings suggest that the ipsilesional eye patch modulated ipsilesional ocular performance in the RH group, presumably resulting from differences in SC activity. Yet, ipsilesional eye patching did not improve eye movements to the contralesional side of space, possibly due to the incomplete contralateral retinocollicular projection in humans.</p></div>","PeriodicalId":55331,"journal":{"name":"Brain and Cognition","volume":"173 ","pages":"Article 106101"},"PeriodicalIF":2.5,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92135980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0