Rene L. Utianski , Gabriela Meade , Joseph R. Duffy , Heather M. Clark , Hugo Botha , Mary M. Machulda , Dennis W. Dickson , Jennifer L. Whitwell , Keith A. Josephs
{"title":"Longitudinal characterization of patients with progressive apraxia of speech without clearly predominant phonetic or prosodic speech features","authors":"Rene L. Utianski , Gabriela Meade , Joseph R. Duffy , Heather M. Clark , Hugo Botha , Mary M. Machulda , Dennis W. Dickson , Jennifer L. Whitwell , Keith A. Josephs","doi":"10.1016/j.bandl.2023.105314","DOIUrl":"10.1016/j.bandl.2023.105314","url":null,"abstract":"<div><p>Most recent studies of progressive apraxia of speech (PAOS) have focused on patients with phonetic or prosodic predominant PAOS to understand the implications of the presenting clinical phenotype. Patients without a clearly predominating speech quality, or mixed AOS, have been excluded. Given the implications for disease progression, it is important to understand these patients early in the disease course to inform appropriate education and prognostication. The aim of this study was to describe a cohort of ten patients with initially mixed PAOS and how their clinical course evolves. Four patients were rated prosodic predominant later on (mild AOS at first visit); five were later designated phonetic (four with more than mild AOS at first visit); one was judged mixed at all visits. The study suggests patients without a clear predominance of speech features<!--> <!-->should still be included in PAOS studies and thought of on the continuum of the disease spectrum.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10407260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complain like you mean it! How prosody conveys suffering even about innocuous events","authors":"Maël Mauchand, Marc D. Pell","doi":"10.1016/j.bandl.2023.105305","DOIUrl":"10.1016/j.bandl.2023.105305","url":null,"abstract":"<div><p>When complaining, speakers can use their voice to convey a feeling of pain, even when describing innocuous events. Rapid detection of emotive and identity features of the voice may constrain how the semantic content of complaints is processed, as indexed by N400 and P600 effects evoked by the final, pain-related word. Twenty-six participants listened to statements describing painful and innocuous events expressed in a neutral or complaining voice, produced by ingroup and outgroup accented speakers. Participants evaluated how hurt the speaker felt under EEG monitoring. Principal Component Analysis of Event-Related Potentials from the final word onset demonstrated N400 and P600 increases when complainers described innocuous vs. painful events in a neutral voice, but these effects were altered when utterances were expressed in a complaining voice. Independent of prosody, N400 amplitudes increased for complaints spoken in outgroup vs. ingroup accents. Results demonstrate that prosody and accent constrain the processing of spoken complaints as proposed in a parallel-constraint-satisfaction model.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10241299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment-induced neuroplasticity after anomia therapy in post-stroke aphasia: A systematic review of neuroimaging studies","authors":"Tijana Simic , Marie-Ève Desjardins , Melody Courson , Christophe Bedetti , Bérengère Houzé , Simona Maria Brambati","doi":"10.1016/j.bandl.2023.105300","DOIUrl":"10.1016/j.bandl.2023.105300","url":null,"abstract":"<div><p>We systematically reviewed the literature on neural changes following anomia treatment post-stroke. We conducted electronic searches of CINAHL, Cochrane Trials, Embase, Ovid MEDLINE, MEDLINE-in-Process and PsycINFO databases; two independent raters assessed all abstracts and full texts. Accepted studies reported original data on adults with post-stroke aphasia, who received behavioural treatment for anomia, and magnetic resonance brain imaging (MRI) pre- and post-treatment. Search results yielded 2481 citations; 33 studies were accepted. Most studies employed functional MRI and the quality of reporting neuroimaging methodology was variable, particularly for pre-processing steps and statistical analyses. The most methodologically robust data were synthesized, focusing on pre- versus post-treatment contrasts. Studies more commonly reported increases (versus decreases) in activation following naming therapy, primarily in the left supramarginal gyrus, and left/bilateral precunei. Our findings highlight the methodological heterogeneity across MRI studies, and the paucity of robust evidence demonstrating direct links between brain and behaviour in anomia rehabilitation.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10236535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandra A.W. Dopierała , David López Pérez , Evelyne Mercure , Agnieszka Pluta , Anna Malinowska-Korczak , Samuel Evans , Tomasz Wolak , Przemysław Tomalski
{"title":"Watching talking faces: The development of cortical representation of visual syllables in infancy","authors":"Aleksandra A.W. Dopierała , David López Pérez , Evelyne Mercure , Agnieszka Pluta , Anna Malinowska-Korczak , Samuel Evans , Tomasz Wolak , Przemysław Tomalski","doi":"10.1016/j.bandl.2023.105304","DOIUrl":"10.1016/j.bandl.2023.105304","url":null,"abstract":"<div><p>From birth, we perceive speech by hearing and seeing people talk. In adults cortical representations of visual speech are processed in the putative temporal visual speech area (TVSA), but it remains unknown how these representations develop. We measured infants’ cortical responses to silent visual syllables and non-communicative mouth movements using functional Near-Infrared Spectroscopy. Our results indicate that cortical specialisation for visual speech may emerge during infancy. The putative TVSA was active to both visual syllables and gurning around 5 months of age, and more active to gurning than to visual syllables around 10 months of age. Multivariate pattern analysis classification of distinct cortical responses to visual speech and gurning was successful at 10, but not at 5 months of age. These findings imply that cortical representations of visual speech change between 5 and 10 months of age, showing that the putative TVSA is initially broadly tuned and becomes selective with age.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10291502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Monaco , M. Mouthon , J. Britz , S. Sato , I. Stefanos-Yakoub , J.M. Annoni , L.B. Jost
{"title":"Embodiment of action-related language in the native and a late foreign language – An fMRI-study","authors":"E. Monaco , M. Mouthon , J. Britz , S. Sato , I. Stefanos-Yakoub , J.M. Annoni , L.B. Jost","doi":"10.1016/j.bandl.2023.105312","DOIUrl":"10.1016/j.bandl.2023.105312","url":null,"abstract":"<div><p>Theories of embodied cognition postulate that language processing activates similar sensory-motor structures as when interacting with the environment. Only little is known about the neural substrate of embodiment in a foreign language (L2) as compared to the mother tongue (L1). In this fMRI study, we investigated embodiment of motor and non-motor action verbs in L1 and L2 including 31 late bilinguals. Half had German as L1 and French as L2, and the other half vice-versa. We collapsed across languages to avoid the confound between language and order of language acquisition. Region of interest analyses showed stronger activation in motor regions during L2 than during L1 processing, independently of the motor-relatedness of the verbs. Moreover, a stronger involvement of motor regions for motor-related as compared to non-motor-related verbs, similarly for L1 and L2, was found. Overall, the similarity between L1 and L2 embodiment seems to depend on individual and contextual factors.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10241312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conceptual representations in the default, control and attention networks are task-dependent and cross-modal","authors":"Philipp Kuhnke , Markus Kiefer , Gesa Hartwigsen","doi":"10.1016/j.bandl.2023.105313","DOIUrl":"10.1016/j.bandl.2023.105313","url":null,"abstract":"<div><p>Conceptual knowledge is central to human cognition. Neuroimaging studies suggest that conceptual processing involves modality-specific and multimodal brain regions in a task-dependent fashion. However, it remains unclear (1) to what extent conceptual feature representations are also modulated by the task, (2) whether conceptual representations in multimodal regions are indeed cross-modal, and (3) how the conceptual system relates to the large-scale functional brain networks. To address these issues, we conducted multivariate pattern analyses on fMRI data. 40 participants performed three tasks—lexical decision, sound judgment, and action judgment—on written words. We found that (1) conceptual feature representations are strongly modulated by the task, (2) conceptual representations in several multimodal regions are cross-modal, and (3) conceptual feature retrieval involves the default, frontoparietal control, and dorsal attention networks. Conceptual representations in these large-scale networks are task-dependent and cross-modal. Our findings support theories that assume conceptual processing to rely on a flexible, multi-level architecture.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10292464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lorenzo Vignali , Yangwen Xu , Jacopo Turini , Olivier Collignon , Davide Crepaldi , Roberto Bottini
{"title":"Spatiotemporal dynamics of abstract and concrete semantic representations","authors":"Lorenzo Vignali , Yangwen Xu , Jacopo Turini , Olivier Collignon , Davide Crepaldi , Roberto Bottini","doi":"10.1016/j.bandl.2023.105298","DOIUrl":"10.1016/j.bandl.2023.105298","url":null,"abstract":"<div><p>Dual Coding Theories (DCT) suggest that meaning is represented in the brain by a double code: a language-derived code in the Anterior Temporal Lobe (ATL) and a sensory-derived code in perceptual and motor regions. Concrete concepts should activate both codes, while abstract ones rely solely on the linguistic code. To test these hypotheses, the present magnetoencephalography (MEG) experiment had participants judge whether visually presented words relate to the senses while we recorded brain responses to abstract and concrete semantic components obtained from 65 independently rated semantic features. Results evidenced early involvement of anterior-temporal and inferior-frontal brain areas in both abstract and concrete semantic information encoding. At later stages, occipital and occipito-temporal regions showed greater responses to concrete compared to abstract features. The present findings suggest that the concreteness of words is processed first with a transmodal/linguistic code, housed in frontotemporal brain systems, and only after with an imagistic/sensorimotor code in perceptual regions.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9977342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interactions of lexical and conceptual representations: Evidence from EEG","authors":"Zohar Eviatar , Nahal Binur , Orna Peleg","doi":"10.1016/j.bandl.2023.105302","DOIUrl":"10.1016/j.bandl.2023.105302","url":null,"abstract":"<div><p>We examined whether meanings automatically activate linguistic forms, and whether these forms affect semantic decisions. Participants were presented sequentially with pairs of pictures and decided whether the objects in the pictures were related. At no point did they name the pictures. The object names of the experimental stimuli were ambiguous either in orthography (homographs), phonology (homophones), or both (homonyms), or unambiguous. We show that the lexical characteristics of the name of the objects affect a semantic decision about real world relations, in an online measure (N400), in addition to offline behavioral measures. We show a dissociation between conceptual and lexical recognition, where an earlier component (N230), was affected by relatedness, but was not sensitive to the lexical characteristics. We interpret this as supporting the hypothesis that semantic recognition occurs before the automatic lexical activation of the object name, but that once linguistic representations are activated, they affect semantic integration.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10450332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgia Thomas , Katie L. McMahon , Emma Finch , David A. Copland
{"title":"Interindividual variability and consistency of language mapping paradigms for presurgical use","authors":"Georgia Thomas , Katie L. McMahon , Emma Finch , David A. Copland","doi":"10.1016/j.bandl.2023.105299","DOIUrl":"10.1016/j.bandl.2023.105299","url":null,"abstract":"<div><p>Most functional MRI studies of language processing have focussed on group-level inference, but for clinical use, the aim is to predict outcomes at an individual patient level. This requires being able to identify atypical activation and understand how differences relate to language outcomes. A language mapping paradigm that selectively activates left hemisphere language regions in healthy individuals allows atypical activation in a patient to be more easily identified. We investigated the interindividual variability and consistency of language activation in 12 healthy participants using three tasks—verb generation, responsive naming, and sentence comprehension—for future presurgical use. Responsive naming produced the most consistent left-lateralised activation across participants in frontal and temporal regions that postsurgical voxel-based lesion-symptom mapping studies suggest are most critical for language outcomes. Studies with a long-term clinical aim of predicting language outcomes in neurosurgical patients and stroke patients should first establish paradigm validity at an individual level in healthy participants.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10064870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lara Navarrete-Orejudo , Xim Cerda-Company , Guillem Olivé , Nadine Martin , Matti Laine , Antoni Rodríguez-Fornells , Claudia Peñaloza
{"title":"Expressive recall and recognition as complementary measures to assess novel word learning ability in aphasia","authors":"Lara Navarrete-Orejudo , Xim Cerda-Company , Guillem Olivé , Nadine Martin , Matti Laine , Antoni Rodríguez-Fornells , Claudia Peñaloza","doi":"10.1016/j.bandl.2023.105303","DOIUrl":"10.1016/j.bandl.2023.105303","url":null,"abstract":"<div><p>Novel word learning ability has been associated with language treatment outcomes in people with aphasia (PWA), and its assessment could inform prognosis and rehabilitation. We used a brief experimental task to examine novel word learning in PWA, determine the value of phonological cueing in assessing learning outcomes, and identify factors that modulate learning ability. Twelve PWA and nineteen healthy controls completed the task, and recall and recognition tests of learning ability. Most PWA showed comparable learning outcomes to those of the healthy controls. Learning assessed via expressive recall was more clearly evidenced with phonological cues. Better single word processing abilities and phonological short-term memory and higher integrity of the left inferior frontal gyrus were related to better learning performance. Brief learning tasks like this one are clinically feasible and hold promise as screening tools of verbal learning in PWA once validated and evaluated for their capacity to predict treatment outcomes.</p></div>","PeriodicalId":55330,"journal":{"name":"Brain and Language","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10429539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}