Clinical Neuropsychologist最新文献

{"title":"Good intentions but bad outcome: Critique of the Minnesota Neuropsychology Conference proposed guidelines.","authors":"Laurence M Binder, Melissa A Friedman, William Milberg, Nancy Hebben","doi":"10.1080/13854046.2026.2738657","DOIUrl":"https://doi.org/10.1080/13854046.2026.2738657","url":null,"abstract":"<p><p><b>Objective:</b> The proposed Minnesota Neuropsychology Conference (MNC) guidelines may become enforceable standards for neuropsychology training. We describe the process and critique the content. <b>Method:</b> Review of the MNC process, proposed guidelines, and related documents. <b>Conclusions:</b> Some assertions in the proposed guidelines about diversification of the neuropsychology workforce and assessment of culturally diverse patients are laudable. However, the encroachment of the proposed guidelines into sociopolitical values, a natural outcome of MNC planning and goals, was in our opinion unfortunate. The guidelines did not obtain consensus from the MNC delegates and were approved by only 58% of American Academy of Clinical Neuropsychology voting members. The National Academy of Neuropsychology declined endorsement and a leading journal (<i>Archives of Clinical Neuropsychology</i>) declined to publish them. The guidelines contain several problems including overemphasis on weakly validated determinants of cognitive function, inappropriate political rhetoric in a scientific discipline that may risk undermining the trust of patients, and an ill-defined call for training in advocacy. The guidelines may threaten standards of scientific and clinical objectivity in training. A recently published competency-based postdoctoral curriculum (Guidotti Breting et al., 2026) that avoids the MNC's controversial sociopolitical language is less divisive for training. We recommend prompt revision.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-18"},"PeriodicalIF":2.6,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Best practice recommendations for spoken and signed language interpreter-mediated clinical neuropsychological services.","authors":"Adriana M Strutt, Lawrence H Pick, Jesus Barreto Abrams, Kendra M Anderson, David Andrés González, Audrina Mullane, Margaret Baker Daniel, Stephen R McCauley","doi":"10.1080/13854046.2026.2732045","DOIUrl":"https://doi.org/10.1080/13854046.2026.2732045","url":null,"abstract":"<p><p><b>Objective:</b> The increasing linguistic and cultural diversity of the United States population has intensified demand for equitable, patient-centered neuropsychological services. Yet, a persistent shortage of bilingual and multilingual neuropsychologists, across both spoken and signed languages, has resulted in growing reliance on interpreters. Despite this reality, empirically informed and clinically actionable guidance for interpreter‑mediated neuropsychological practice remains limited. This manuscript addresses the urgent need for well‑articulated best practice recommendations tailored to interpreter‑mediated clinical neuropsychological services in the United States. <b>Method:</b> This paper presents an expert‑informed narrative synthesis of (a) peer‑reviewed empirical literature, (b) existing national and international professional guidance, and (c) interdisciplinary expert consensus grounded in the authors' training and work experience. Relevant ethical, legal, clinical, training, and systems‑level considerations were integrated to develop practice‑focused recommendations responsive to U.S. healthcare contexts. <b>Results:</b> The manuscript outlines a comprehensive framework for interpreter‑mediated neuropsychological care, including clinician-interpreter collaboration, interpreter qualifications and credentialing systems, curricular and training recommendations, ethical and legal obligations, and financial considerations specific to the U.S. healthcare system. A step‑by‑step protocol is provided to guide pre‑assessment, assessment, and post‑assessment phases of interpreter‑mediated neuropsychological services, with explicit inclusion of both spoken and signed language interpretation. <b>Conclusion:</b> These best practice recommendations offer a clinically actionable foundation for enhancing the quality, equity, and sustainability of interpreter‑mediated neuropsychological services in the United States. By directly addressing persistent gaps in training and clinical implementation, this framework supports current practice while remaining adaptable to ongoing empirical advances and future refinement in this evolving area of clinical neuropsychology.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-39"},"PeriodicalIF":2.6,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149013036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and neuropsychological course of young adult patient with anti-GAD-65 autoimmune encephalitis: A case report.","authors":"Matthew S Phillips, Malorie E Watson, Brian Ramanauskas, Devin M Ulrich, Tania Jawad, Anna Serafini, Jason R Soble","doi":"10.1080/13854046.2026.2735490","DOIUrl":"https://doi.org/10.1080/13854046.2026.2735490","url":null,"abstract":"<p><p><b>Objective:</b> Among autoimmune limbic encephalitis syndromes, glutamic acid decarboxylase 65 (GAD65) antibody-associated syndromes represent a relatively rare and clinically heterogeneous subtype characterized by prominent temporal lobe involvement and diverse neurological manifestations. GAD65 is an intracellular antigen involved in gamma-aminobutyric acid (GABA) synthesis, and associated autoantibodies have been identified across several autoimmune and neurological conditions with limited diagnostic specificity and variable neurological and neuropsychological presentations. <b>Method:</b> This case report involves a young woman with confirmed anti-GAD65 autoimmune encephalitis (AE), who underwent serial neuropsychological evaluations over a period of two years. <b>Results:</b> The patient exhibited refractory temporal lobe epilepsy, neuropsychiatric and behavioral disturbance, and a pattern of neuropsychological deficits suggesting prominent temporal lobe dysfunction. Despite being untreated for approximately two years, the patient did not demonstrate a pattern of globally impaired neuropsychological dysfunction. Rather, her profile showed primary, severe impairment in memory and semantically-mediated language functions. What is particularly striking about this case was the severity of the patient's neurocognitive deficits. Specifically, she had a complete amnestic memory syndrome and substantial degradation of semantic knowledge, despite only experiencing seizures for two years, prior to which she was functioning normally. <b>Conclusions:</b> This case represents an illustrious example of how neuropsychological evaluation played a critical role in documenting the patient's persisting deficits to more accurately tailor treatment recommendations and planning. It also represents a sobering example of the kinds of lasting deficits that can occur without timely diagnosis and treatment.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-13"},"PeriodicalIF":2.6,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148992653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-week changes on the Independent Living Scales in older adults: Proof of concept for quantifying subtle functional decline.","authors":"Lakshmi Kannan, Kevin Duff","doi":"10.1080/13854046.2026.2730448","DOIUrl":"https://doi.org/10.1080/13854046.2026.2730448","url":null,"abstract":"<p><p><b>Objective</b>: Identifying subtle change in daily functioning is important for diagnosing late life cognitive disorders. This proof-of-concept study sought to develop standardized regression-based (SRB) equations for the Independent Living Scales (ILS) and examine their application in older adults over one week to quantify subtle functional changes. <b>Method:</b> Two hundred sixteen older adults (86% cognitively unimpaired, 14% cognitively impaired) were administered the ILS, a multi-dimensional standardized measure of daily functioning, during a baseline visit and one week later. In the unimpaired participants, linear regression models predicted one-week ILS scores by baseline ILS scores, demographics, retest intervals, and premorbid intellect. SRB equations were applied to both groups and compared with independent t-tests and chi-square tests. <b>Results:</b> One-week retest scores were significantly (<i>p</i> < 0.001) predicted in the unimpaired individuals, with regression models accounting for 14-51% of the variance. As expected, SRB-derived <i>z</i>-scores differed significantly between groups, with the impaired group demonstrating more negative values for the ILS Full Scale (<i>p =</i> 0.03) and 2 of 5 subscales (<i>p</i> ≤ 0.002). Chi-square analyses revealed that smaller-than-expected retest performance was overrepresented in impaired participants (e.g. ILS Full Scale: impaired = 30%, unimpaired = 5%). <b>Conclusion:</b> Using SRB methodology, change scores on the ILS across one week were developed and showed expected group differences. These change scores, which correct for practice effects and expected variability across one week, have the potential to identify subtle functional decline in those at risk for dementia. Future research could expand this methodology to other functional scales across longer retest intervals.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-15"},"PeriodicalIF":2.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling uncertainty in performance validity testing with Bayesian logistic regression.","authors":"Lee Ashendorf","doi":"10.1080/13854046.2026.2726210","DOIUrl":"https://doi.org/10.1080/13854046.2026.2726210","url":null,"abstract":"<p><p><b>Objective:</b> The aggregation of multiple performance validity tests (PVTs) into a summary validity determination is an established challenge in neuropsychology. The standard dichotomous accumulation approach relies upon binary recoding of continuous PVT scores and yields ambiguous outcomes in a sizable proportion of cases. This study evaluated Bayesian logistic regression as a framework for estimating the posterior probability of an invalid profile from continuous embedded PVT scores. <b>Method:</b> A retrospective sample of 233 military veterans was classified into Valid (<i>n</i> = 132), Ambiguous (<i>n</i> = 55), and Invalid (<i>n</i> = 46) groups based on three standalone PVTs. A Bayesian logistic regression model was trained on the Valid and Invalid groups using six embedded PVTs as continuous standardized predictors. The Ambiguous group was withheld from training and subsequently evaluated using model-derived posterior probability estimates. <b>Results:</b> The full six-predictor model yielded the highest posterior probability. PVTs varied in inclusion evidence. Probability distributions were consistently low in the Valid group, consistently high in the Invalid group, and markedly heterogeneous in the Ambiguous group. <b>Conclusions:</b> Bayesian logistic regression provides a viable framework for probabilistic PVT aggregation that preserves continuous score information, accounts for intercorrelation among predictors, and models genuine uncertainty when present. Validation in more diverse samples using sophisticated outcome measures is needed.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-15"},"PeriodicalIF":2.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing bias in informant ratings: Development of an Atypical Change Index for the Iowa Scales of Personality Change.","authors":"Mark Bowren, Kimberly C Diah, Steven W Anderson, Kenneth Manzel, Joseph Barrash, Daniel Tranel","doi":"10.1080/13854046.2026.2717158","DOIUrl":"https://doi.org/10.1080/13854046.2026.2717158","url":null,"abstract":"<p><p><b>Objective:</b> Neuropsychological assessments should employ scientifically supported instruments to detect bias. To our knowledge, there are no validated measures for assessing bias in informant ratings of personality changes following brain injuries. We report the development of such a measure for the Iowa Scales of Personality Change (ISPC). <b>Method:</b> ISPC personality change ratings were obtained from informants for: (1) 48 Research Registry patients with chronic, focal, ventromedial prefrontal cortex lesions (vmPFC group), and (2) 226 individuals undergoing independent neuropsychological evaluations in the context of litigation (INE group). An \"Atypical Change Index\" was developed using vmPFC group ISPC data, comprising scales for which extreme changes were rare among vmPFC patients (≤2.5%). We hypothesized that the INE group would have higher Atypical Change Index scores compared to the vmPFC group. To avoid circularity, we used repeated cross-validations to separate the vmPFC group data into \"train\" sets for identifying scales for the Atypical Change Index, and \"test\" sets for comparing the Atypical Change Index across vmPFC and INE groups. <b>Results:</b> The INE group had statistically significantly higher Atypical Change Index scores than the vmPFC group (<i>p</i> < .001). One vmPFC patient (2.1% of the group) had an Atypical Change Index score > 1, compared to 64 INE patients (28.3% of the group) with scores > 1. <b>Conclusions:</b> Our findings provide initial support for the potential of the Atypical Change Index to detect bias in informant ratings on the ISPC. Further investigation is required to evaluate the validity of this index.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-23"},"PeriodicalIF":2.6,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultural and linguistic adaptation, preliminary psychometric characterization, and reference data for the Turkish verbal FCSRT-16.","authors":"Jbid Dursun-Uncu, Zerrin Yıldırım, Çiğdem Ulaşoğlu-Yıldız, İbrahim Hakan Gürvit","doi":"10.1080/13854046.2026.2719746","DOIUrl":"https://doi.org/10.1080/13854046.2026.2719746","url":null,"abstract":"<p><p><b>Objective:</b> The Free and Cued Selective Reminding Test uses controlled learning to assess hippocampal-type memory impairment. This study culturally and linguistically adapted three Turkish verbal forms of the 16-item test (FCSRT-16TR) and characterized their psychometric properties, score-level comparability, and demographic reference estimates. <b>Method:</b> The complete-case reference sample comprised 285 cognitively unimpaired native Turkish-speaking adults aged 18-87 years. A pilot study (<i>N</i> = 45) refined the stimulus sets. Item response theory (IRT) analyses were conducted in a broader dataset with complete item-level responses (<i>N</i> = 387). Score-level comparability was examined using omnibus and two one-sided equivalence tests. Demographic models included age, education, and sex. <b>Results:</b> Score-level performance was broadly comparable across forms, although one total-free-recall contrast was borderline under the prespecified equivalence criterion. Continuous demographic models were developed for total free recall (TFR) and delayed free recall (DFR). Age showed significant nonlinear associations with both outcomes, whereas higher education and female sex predicted better performance. The models explained 35.2% and 25.2% of TFR and DFR variance, respectively. Under 10-fold cross-validation, predictive R² values were .320 and .233, with root mean square error (RMSE) values of 4.39 and 1.68, respectively. <b>Conclusions:</b> The FCSRT-16TR provides three adapted Turkish verbal forms with broadly comparable score-level performance and demographically adjusted reference estimates for the principal free-recall outcomes. These estimates provide a language-specific reference framework for cognitively unimpaired Turkish-speaking adults but should not be interpreted as diagnostic cutoffs or evidence of within-person form interchangeability.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-22"},"PeriodicalIF":2.6,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construct validity of performance validity tests across multiple mixed-clinical samples.","authors":"Emma R Popescu, Mira I Leese, Jason R Soble, Jarett E Roseberry, S Kristian Hill","doi":"10.1080/13854046.2026.2718391","DOIUrl":"https://doi.org/10.1080/13854046.2026.2718391","url":null,"abstract":"<p><strong>Objective: </strong>Few studies have systematically assessed construct validity across a diverse set of performance validity tests (PVTs). Clarifying whether PVTs measure a common construct or distinct aspects of performance validity has important clinical implications for neuropsychological data interpretation and PVT selection.</p><p><strong>Methods: </strong>This study evaluated the latent structure of PVTs using retrospective data from multiple mixed-clinical samples (Sample 1: <i>N</i> = 115, Sample 2: <i>N</i> = 297; Sample 3: <i>N</i> = 160), with diverse mental health and neurocognitive diagnoses. Each sample was administered a variety of embedded and freestanding PVTs, and the latent structure was examined using exploratory factor analyses (Samples 1-2) and confirmatory factor analysis (CFA; Sample 3).</p><p><strong>Results: </strong>Initial analyses supported a unidimensional structure (Sample 1), whereas Samples 2-3 provided converging evidence for a two-factor solution characterized by moderately to strongly correlated <i>Memory</i> and <i>Non-Memory</i> factors (<i>r</i> = .65 to .71) and excellent model fit in Sample 3 (robust comparative fit index = .99, robust root mean square error of approximation = .045, standardized root mean square residual = .038). Memory-based PVTs demonstrated stronger and more consistent loadings than non-memory PVTs across samples.</p><p><strong>Conclusions: </strong>Findings were consistent with a hierarchical organization with a general PVT construct at the highest strata and closely related <i>Memory</i> and <i>Non-Memory</i> factors nested beneath. Alternative design-based explanations are also considered. Clinically, results support the continued use of multiple memory and non-memory-based PVTs throughout a neuropsychological assessment. Future replication is needed using a prospective design with larger, more demographically and clinically diverse samples.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-21"},"PeriodicalIF":2.6,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deficits in the knowledge of social norms and their correlates in Alzheimer's disease.","authors":"Thomas Carrier, Isabelle Rouleau, Marie-Anne St-Georges, Parsa Afrooz, Maxime Montembeault","doi":"10.1080/13854046.2026.2712921","DOIUrl":"10.1080/13854046.2026.2712921","url":null,"abstract":"<p><p><b>Objective:</b> Compared to other components of social cognition, knowledge of social norms has received less attention in the scientific literature. While social cognitive and semantic memory deficits appear early in the course of Alzheimer's disease (AD), no study has examined knowledge of social norms at earlier stages of the disease. In addition, it is unclear whether the knowledge of social norms in AD is associated with socioemotional deficits, as may be seen in the behavioral variant of frontotemporal dementia (bvFTD). <b>Method:</b> This study included 136 participants with amnestic mild cognitive impairment (aMCI), 134 with AD, most of whom were younger than 65 years, 280 with bvFTD, and 361 older healthy controls (HC). All participants were selected from the National Alzheimer's Coordinating Center (NACC). They completed the Social Norms Questionnaire (SNQ), which assesses the tendency to break or overadhere to social norms. They also completed tests assessing executive, semantic, and socioemotional functions. <b>Results</b>: Between-group comparisons showed that individuals with AD and aMCI made significantly more Break and Overadhere errors than HC, while they demonstrated better social norms knowledge than individuals with bvFTD. In aMCI and AD, social norms overadherence errors were most consistently associated with executive functioning. In bvFTD, semantic memory was the most consistent correlate across all SNQ variables. <b>Conclusions:</b> These findings may help clinicians and researchers better understand social cognitive changes in patients, support the inclusion of social norms knowledge assessment within broader neuropsychological evaluations, and provide complementary insight into the cognitive correlates of social knowledge loss in major neurocognitive disorders.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-18"},"PeriodicalIF":2.6,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction.","authors":"","doi":"10.1080/13854046.2026.2715892","DOIUrl":"https://doi.org/10.1080/13854046.2026.2715892","url":null,"abstract":"","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1"},"PeriodicalIF":2.6,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148686625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}