Comptes Rendus Biologies最新文献

筛选
英文 中文
Axon regeneration: an issue of translation. 轴突再生:一个翻译问题。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-12-12 DOI: 10.5802/crbiol.169
Julia Schaeffer, Stephane Belin
{"title":"Axon regeneration: an issue of translation.","authors":"Julia Schaeffer, Stephane Belin","doi":"10.5802/crbiol.169","DOIUrl":"10.5802/crbiol.169","url":null,"abstract":"<p><p>In the mammalian central nervous system (CNS), adult neurons fail to regenerate spontaneously upon axon injury, which leads to a permanent and irreversible loss of neuronal functions. For more than 15 years, much effort was invested to unlock axon regrowth programs based on extensive transcriptomic characterization. However, it is now well described that mRNA and protein levels correlate only partially in cells, and that the transcription process (from DNA to mRNA) may not directly reflect protein expression. Conversely, the translation process (from mRNA to protein) provides an additional layer of gene regulation. This aspect has been overlooked in CNS regeneration. In this review, we discuss the limitations of transcriptomic approaches to promote CNS regeneration and we provide the rationale to investigate translational regulation in this context, and notably the regulatory role of the translational complex. Finally, we summarize our and others’ recent findings showing how variations in the translational complex composition regulate selective (mRNA-specific) translation, thereby controlling CNS axon regrowth.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"249-258"},"PeriodicalIF":0.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ORCHAMP: an observation network for monitoring biodiversity and ecosystem functioning across space and time in mountainous regions. ORCHAMP:用于监测山区生物多样性和生态系统功能的跨时空观测网络。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-11-25 DOI: 10.5802/crbiol.165
Wilfried Thuiller, Amélie Saillard, Sylvain Abdulhak, Vincent Augé, Carole Birck, Richard Bonet, Philippe Choler, Anne Delestrade, Georges Kunstler, Marie-France Leccia, Bertrand Lienard, Jérome Poulenard, Jean-Gabriel Valay, Arthur Bayle, Nicolas Bonfanti, Lenka Brousset, Léa Bizard, Irene Calderón-Sanou, Cédric Dentant, Camille Desjonquères, Ludovic Gielly, Maya Guéguen, Frédéric Guiter, Mickael Hedde, Eric Hustache, Norine Kedhim, Pierre Lapenu, Nicolas Le Guillarme, Lise Marchal, Chloé Mahieu, Gabrielle Martin, Camille Martinez-Almoyna, Vincent Miele, Jérôme Murienne, Yoan Paillet, Maxime Rome, Julien Renaud
{"title":"ORCHAMP: an observation network for monitoring biodiversity and ecosystem functioning across space and time in mountainous regions.","authors":"Wilfried Thuiller, Amélie Saillard, Sylvain Abdulhak, Vincent Augé, Carole Birck, Richard Bonet, Philippe Choler, Anne Delestrade, Georges Kunstler, Marie-France Leccia, Bertrand Lienard, Jérome Poulenard, Jean-Gabriel Valay, Arthur Bayle, Nicolas Bonfanti, Lenka Brousset, Léa Bizard, Irene Calderón-Sanou, Cédric Dentant, Camille Desjonquères, Ludovic Gielly, Maya Guéguen, Frédéric Guiter, Mickael Hedde, Eric Hustache, Norine Kedhim, Pierre Lapenu, Nicolas Le Guillarme, Lise Marchal, Chloé Mahieu, Gabrielle Martin, Camille Martinez-Almoyna, Vincent Miele, Jérôme Murienne, Yoan Paillet, Maxime Rome, Julien Renaud","doi":"10.5802/crbiol.165","DOIUrl":"10.5802/crbiol.165","url":null,"abstract":"<p><p>Recent climate and land use change, and pollution have led to concerning alterations in biodiversity and ecosystem functions, jeopardizing nature’s contributions to people. Mountainous regions are not immune to these threats, experiencing the impacts of global warming, increased recreational activities, and changes in agricultural practices. Leveraging the natural elevational gradients of mountain environments, the ORCHAMP program was established in 2016 as a comprehensive initiative to monitor, understand, and predict the repercussions of environmental changes on biodiversity and associated ecosystem functions in the French Alps and Pyrenees.\u0000\u0000Beyond its monitoring role, ORCHAMP has catalyzed the development of tools for data integration, statistical analyses, visualization, and AI-based automated data processing and predictions. Through a combination of traditional sampling methods (e.g., botanical surveys) and cutting-edge technologies (remote-sensing, environmental DNA, video, and acoustic sensors), the program offers a holistic approach to understanding how biodiversity faces environmental changes. By showcasing examples and key results, this paper provides an overview of ORCHAMP’s advancements and outlines potential future directions. The broad inclusion of diverse monitoring techniques and data treatments positions ORCHAMP as a pioneering effort, paving the way for long-term insights into biodiversity dynamics—a crucial step toward effective conservation strategies.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"223-247"},"PeriodicalIF":0.7,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Biosecurity and epidemiological surveillance]. [生物安全和流行病监测]。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-11-13 DOI: 10.5802/crbiol.166
Alain-Jacques Valleron
{"title":"[Biosecurity and epidemiological surveillance].","authors":"Alain-Jacques Valleron","doi":"10.5802/crbiol.166","DOIUrl":"10.5802/crbiol.166","url":null,"abstract":"<p><p>Biosecurity is a word including, in French, two concepts which are differently expressed in the English literature: the biosafety (to prevent accidental releases of infectious agents, for example, in research laboratories) and the biosecurity (to prevent the voluntary dispersion of infectious agents by bioterrorists, for example). Up to now, bioterrorism using a biological weapon has been very rare. Epidemiological surveillance is frequently seen as an efficient tool to achieve a better biosafety, and increase biosecurity. However, biosecurity requires an alert system. Traditional surveillance, which was developed to help to design the health policies, lacks the sensitivity and rapid response delay necessary for alert. Biology brings new opportunities for alert and surveillance. Examples are the monitoring of sewer systems and the development of CRISPR tools for detection of biological agents. A new problem is that these tools can be used out of the research laboratories, because they are relatively cheap and easy to develop. Finally, whatever the method used to identify quickly a new hazard, the key problem is the “preparedness” to identify and connect quickly the biomedical experts able to provide the best response to this hazard.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"181-186"},"PeriodicalIF":0.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generating neurons in the embryonic and adult brain: compared principles and mechanisms. 胚胎和成人大脑中神经元的生成:原理和机制比较。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-11-13 DOI: 10.5802/crbiol.167
Mathilde Chouly, Laure Bally-Cuif
{"title":"Generating neurons in the embryonic and adult brain: compared principles and mechanisms.","authors":"Mathilde Chouly, Laure Bally-Cuif","doi":"10.5802/crbiol.167","DOIUrl":"10.5802/crbiol.167","url":null,"abstract":"<p><p>Neurogenesis is a lifelong process, generating neurons in the right amount, time and place and with the correct identity to permit the growth, function, plasticity and repair of the nervous system, notably the brain. Neurogenesis originates from neural progenitor cells (NPs), endowed with the capacity to divide, renew to maintain the progenitor population, or commit to engage in the neurogenesis process. In the adult brain, these progenitors are classically called neural stem cells (NSCs). We review here the commonalities and differences between NPs and NSCs, in their cellular and molecular attributes but also in their potential, regulators and lineage, in the embryonic and adult brains. Our comparison is based on the two most studied model systems, namely the telencephalon of the zebrafish and mouse. We also discuss how the population of embryonic NPs gives rise to adult NSCs, and outstanding questions pertaining to this transition.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"199-221"},"PeriodicalIF":0.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Nanomedicines for the treatment of serious diseases and dual research]. [用于治疗严重疾病和双重研究的纳米药物]。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-11-13 DOI: 10.5802/crbiol.168
Patrick Couvreur
{"title":"[Nanomedicines for the treatment of serious diseases and dual research].","authors":"Patrick Couvreur","doi":"10.5802/crbiol.168","DOIUrl":"10.5802/crbiol.168","url":null,"abstract":"<p><p>The use of nanotechnologies for the encapsulation of pharmacologically active molecules (nanomedicines) has enhanced the delivery of these molecules within the body after administration. By releasing the active ingredient at the level of pathological cells and tissues, these nanocarriers help reduce toxicity while improving therapeutic efficacy. They also protect fragile molecules from rapid metabolization and can promote their intracellular penetration. Nanomedicines have made significant advances in various therapeutic areas such as oncology, infectious diseases, and several neurological disorders. They have also contributed to groundbreaking discoveries, including the introduction of the first mRNA vaccine (against COVID-19), and have improved certain imaging and diagnostic techniques, too. Depending on the country and therapeutic indications, between 40 to 60 nanomedicines are currently on the market, with over a hundred in clinical trials. This review aims to describe and discuss the characteristics and functionalities of the different generations of nanocarriers, from their inception to the present day, discussing the prospects they offer for the production of therapeutic proteins, for facilitating gene editing (CRISPR/Cas9), and for enabling immune checkpoint blockade in oncology. The potential of extracellular vesicles and exosomes as drug carriers is also explored. These advances compel researchers to consider the dual risks, both conscious and unconscious, that they may pose.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"187-198"},"PeriodicalIF":0.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Biodiversity : a need for clarification]. [生物多样性:需要澄清]。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-11-07 DOI: 10.5802/crbiol.163
Guillaume Lecointre
{"title":"[Biodiversity : a need for clarification].","authors":"Guillaume Lecointre","doi":"10.5802/crbiol.163","DOIUrl":"10.5802/crbiol.163","url":null,"abstract":"<p><p>Ever since the term “biodiversity” was first defined, it has been used in a mixed way, referring on the one hand to the characterisation of living organisms (which is the domain of systematics), and on the other hand to their functional interactions (which are the domain of ecology). This ambiguity has led to the terms biodiversity and ecosystem being used almost synonymously, a mistake that is both epistemologically and politically damaging. To clear up this confusion, the term biodiversity should be reserved for what we observe when we characterise or discover “what there is” (a task for systematics) at the three infra-specific, specific and supra-specific levels, and the term ecosystem should be reserved for what we observe when we are interested in the functional interactions (“what it does”, a task for ecology) between living organisms, and between the latter and the abiotic environment.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"175-180"},"PeriodicalIF":0.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oncogenic processes: a neglected parameter in the evolutionary ecology of animals. 致癌过程:动物进化生态学中一个被忽视的参数。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-11-07 DOI: 10.5802/crbiol.159
Frédéric Thomas, Klara Asselin, Nick MacDonald, Lionel Brazier, Jordan Meliani, Beata Ujvari, Antoine Marie Dujon
{"title":"Oncogenic processes: a neglected parameter in the evolutionary ecology of animals.","authors":"Frédéric Thomas, Klara Asselin, Nick MacDonald, Lionel Brazier, Jordan Meliani, Beata Ujvari, Antoine Marie Dujon","doi":"10.5802/crbiol.159","DOIUrl":"10.5802/crbiol.159","url":null,"abstract":"<p><p>Cancer is a biological process that emerged at the end of the Precambrian era with the rise of multicellular organisms. Traditionally, cancer has been viewed primarily as a disease relevant to human and domesticated animal health, attracting attention mainly from oncologists. In recent years, however, the community of ecologists and evolutionary biologists has recognized the pivotal role of cancer-related issues in the evolutionary paths of various species, influencing multiple facets of their biology. It has become evident that overlooking these issues is untenable for a comprehensive understanding of species evolution and ecosystem functioning. In this article, we highlight some significant advancements in this field, also underscoring the pressing need to consider reciprocal interactions not only between cancer cells and their hosts but also with all entities comprising the holobiont. This reflection gains particular relevance as ecosystems face increasing pollution from mutagenic substances, resulting in a resurgence of cancer cases in wildlife.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"137-157"},"PeriodicalIF":0.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The milpa, from Mesoamerica to present days, a multicropping traditional agricultural system serving agroecology. 从中美洲到现在的密尔帕,是一种服务于农业生态学的多作物传统农业系统。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-11-06 DOI: 10.5802/crbiol.164
Noa Vazeux-Blumental, Domenica Manicacci, Maud Tenaillon
{"title":"The milpa, from Mesoamerica to present days, a multicropping traditional agricultural system serving agroecology.","authors":"Noa Vazeux-Blumental, Domenica Manicacci, Maud Tenaillon","doi":"10.5802/crbiol.164","DOIUrl":"10.5802/crbiol.164","url":null,"abstract":"<p><p>The association of maize (Zea mays ssp. mays), common bean (Phaseolus vulgaris), and squash (Cucurbita ssp.) within the milpa represents the most emblematic multi-cropping subsistence system of Mesoamerica. This system was likely established in the Guerrero-Jalisco area in southwestern Central Mexico shortly after—or perhaps even before—the domestication of the three taxa. Its success relies on several factors: complementarity of nutritional intakes, resilience to biotic and abiotic constraints, and the mobilization of positive interactions between the three taxa, enabling the system to be productive under input-limited conditions. Higher yields compared to sole-cropping have frequently been described and attributed to the complementarity between the aerial and root systems of the different taxa of the milpa, as well as to direct and indirect facilitation processes involving root exudates, bacterial symbioses, and the mycorrhizal network. In Europe, while practiced until recently, the milpa has gradually been abandoned in favor of maize sole-cropping, except in some isolated regions (such as Transylvania) where this traditional agricultural system has persisted. The question of whether varieties of the three taxa used in multi-cropping systems were co-introduced to Europe at the time of the discovery of the Americas, as opposed to being re-associated later in Europe, remains open. It is important to note that maize usage differed: maize of flint type is coarsely ground for the preparation of polenta in Europe, while in Mesoamerica, tropical varieties are soaked in alkaline solution to improve nutritional quality before being finely ground to make tortilla dough. Recently, maize-bean intercropping has been reintroduced into modern European agricultural systems. However, the use of elite varieties and chemical inputs in conventional conducts prevents full exploitation of positive interactions between species. We argue here that milpa has an important role to play in the agroecological transition. In this context, we propose avenues for the selection of varieties that promote synergies between species and discuss the constraints linked to its mechanization.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"159-173"},"PeriodicalIF":0.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Species abundance, urn models, and neutrality. 物种丰度、瓮模型和中性。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-10-02 DOI: 10.5802/crbiol.162
Jerome Chave
{"title":"Species abundance, urn models, and neutrality.","authors":"Jerome Chave","doi":"10.5802/crbiol.162","DOIUrl":"10.5802/crbiol.162","url":null,"abstract":"<p><p>The neutral theory of biodiversity and biogeography has stimulated much research in community ecology. Here, exact results are used to apply neutral model predictions to large regional samples. Three complementary neutral models are presented: the Ewens canonical neutral model, a model of subdivided ecological communities, and a “diversity begets diversity” neutral model. For all three models, an exact sampling formula is provided, and a new R package neutr, is presented. This package is used to fit species abundances from regional inventories of tropical forest trees in the Amazon, tropical Africa and Southeast Asia. It is shown that the neutral models fit well empirical data for all but the few most abundant species (from 6 to 40 depending on the continent). When the parameter θ is taken as an index or regional diversity, the Amazonia and Southeast Asia emerge with similar regional diversities (θ = 654 for Amazonia, versus θ = 726 for Southeast Asia), with a less diverse tropical African tree flora (θ = 219). The model infers 10,141 tree species with at least 50 individuals in Amazonia, 3477 in tropical Africa and 9915 in Southeast Asia. The spatially subdivided neutral model provides clear evidence for a spatial substructure in all three regional floras. These results show how neutral models are useful to explore regional patterns of species abundance and to provide insights about regional species pools.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"119-135"},"PeriodicalIF":0.7,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incomplete divisions between sister germline cells require Usp8 function. 姐妹生殖细胞之间的不完全分裂需要 Usp8 的功能。
IF 0.7 4区 生物学
Comptes Rendus Biologies Pub Date : 2024-09-30 DOI: 10.5802/crbiol.161
Juliette Mathieu, Jean-René Huynh
{"title":"Incomplete divisions between sister germline cells require Usp8 function.","authors":"Juliette Mathieu, Jean-René Huynh","doi":"10.5802/crbiol.161","DOIUrl":"10.5802/crbiol.161","url":null,"abstract":"<p><p>Cytokinetic abscission is the final step of cell division, resulting in two separate daughter cells. While abscission is typically complete across most cell types, germline cells, which produce sexual gametes, do not finish cytokinesis, maintaining connections between sister cells. These connections are essential for sharing cytoplasm as they differentiate into oocyte and sperm. First, we outline the molecular events of cytokinesis during both complete and delayed abscission, highlighting the role of the ESCRT-III proteins. We then focus on recent discoveries that reveal the molecular mechanisms blocking abscission in Drosophila germline cells. The enzyme Usp8 was identified as vital for ensuring incomplete cytokinesis through the regulation of ESCRT-III ubiquitination and localization. Finally, we explore how the processes of incomplete cytokinesis could hold evolutionary importance, suggesting additional studies into choanoflagellates to comprehend the origins of multicellularity.</p>","PeriodicalId":55231,"journal":{"name":"Comptes Rendus Biologies","volume":"347 ","pages":"109-117"},"PeriodicalIF":0.7,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信