Current Problems in Cancer最新文献_第10页

Changing trends in disease burden of lung cancer in China from 1990-2019 and following 15-year prediction 1990～2019年中国癌症疾病负担变化趋势及15年预测。

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-11-04 DOI: 10.1016/j.currproblcancer.2023.101036

Di Zhao , Jinzhi Lu , Wen Zeng , Cong Zhang , Yonghao You

{"title":"Changing trends in disease burden of lung cancer in China from 1990-2019 and following 15-year prediction","authors":"Di Zhao , Jinzhi Lu , Wen Zeng , Cong Zhang , Yonghao You","doi":"10.1016/j.currproblcancer.2023.101036","DOIUrl":"10.1016/j.currproblcancer.2023.101036","url":null,"abstract":"<div><h3>Background</h3><p>As lung cancer becomes a primary source of death in China, investigation on incidence rate, death rate, and disability-adjusted life years (DALYs) is of great significance to optimize prevention measures and allocation of healthcare resources.</p></div><div><h3>Methods</h3><p>We utilized data from the Global Burden of Disease (GBD) database to evaluate the incidence rate, death rate, and DALYs of lung cancer in China from 1990 to 2019. Analysis of lung cancer risk factor-related death rate and DALYs was performed. Age-standardized rates (ASR) and estimated annual percentage change (EAPC) were calculated. The incidence trend of lung cancer from 2020 to 2034 was predicted by the Nordpred age-period-cohort (APC) model.</p></div><div><h3>Results</h3><p>Age-standardized incidence rate (ASIR) increased from 30.2/100000 (95 % UI 26.2–34.3) in 1990 to 41.7/100000 (95 % UI 35.2–48.8) in 2019, and EAPC was 1.33 (95 % CI 1.16–1.49). From 1990 to 2019, men were noted for the highest incidence rate, death rate, and DALYs rate across three age groups (15–49 years, 50–69 years, and over 70). During this period, the ASIR of lung cancer in females was always lower than that in males. The predominant risk factors of lung cancer were smoking, air pollution, and diet, among which smoking was the most significant one. The analysis results showed that new cases and deaths may increase in the following 15 years since 2020 in the context of lung cancer.</p></div><div><h3>Conclusion</h3><p>Faced with the heavy burden of lung cancer, China must issue corresponding policies and roll out prevention avenues against smoking and air pollution.</p></div>","PeriodicalId":55193,"journal":{"name":"Current Problems in Cancer","volume":"48 ","pages":"Article 101036"},"PeriodicalIF":2.6,"publicationDate":"2023-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors for omental metastasis and the effect of omentectomy on survival in type 2 endometrial cancer patients 2型子宫内膜癌症患者大网膜转移的危险因素及大网膜切除术对生存率的影响。

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-10-13 DOI: 10.1016/j.currproblcancer.2023.101018

Varol Gülseren , İlker Çakır , Esra Canan Kelten , Aykut Özcan , Muzaffer Sancı , Ertuğrul Şen , Zübeyde Emiralioğlu Çakır , İsa Aykut Özdemir , Kemal Güngördük

{"title":"Risk factors for omental metastasis and the effect of omentectomy on survival in type 2 endometrial cancer patients","authors":"Varol Gülseren , İlker Çakır , Esra Canan Kelten , Aykut Özcan , Muzaffer Sancı , Ertuğrul Şen , Zübeyde Emiralioğlu Çakır , İsa Aykut Özdemir , Kemal Güngördük","doi":"10.1016/j.currproblcancer.2023.101018","DOIUrl":"10.1016/j.currproblcancer.2023.101018","url":null,"abstract":"<div><p><span><span><span>To investigate the risk factors for occult omental metastasis and the effect of </span>omentectomy<span> on the survival of type 2 endometrial cancer (EC) patients. This study enrolled patients who were diagnosed with high-risk (grade 3, serous, clear cell, undifferentiated, carcinosarcoma, or mixed type) EC between 2000 and 2021 and underwent surgery in our center. Data from 482 patients were analyzed retrospectively. Omentectomy was performed in 405 (84.0%) patients. Omental metastases were detected in 61 (12.7%) patients. Eighteen (29.5%) of these metastases were occult. Adnexal involvement, malignant </span></span>cytology<span>, and peritoneal spread were independent risk factors for omental metastasis. The 5-year overall survival (OS) rate was 59.5% in patients who underwent omentectomy and 64.7% in those who did not (</span></span><em>P</em> = 0.558). In patients with and without omental metastases, the overall 5-year OS rates were 34.9% and 63.5%, respectively (<em>P</em><span> < 0.001). The 5-year OS rates of patients with a normal omentum, gross tumors, and occult metastases were 63.5%, 26.9%, and 52.5%, respectively (</span><em>P</em> < 0.001). Omental metastases is not uncommon in type II endometrial cancer; approximately one third of patients have occult metastases. Factors - positive cytology, adnexal involvement, and peritoneal involvement are associated with higher probability of omental metastases.</p></div>","PeriodicalId":55193,"journal":{"name":"Current Problems in Cancer","volume":"47 6","pages":"Article 101018"},"PeriodicalIF":2.6,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovations for the integration of palliative care for hematologic malignancies 整合血液恶性肿瘤姑息治疗的创新

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-10-01 DOI: 10.1016/j.currproblcancer.2023.101011

Neha Kayastha , Alison R. Kavanaugh , Jason A. Webb , Thomas W. LeBlanc

{"title":"Innovations for the integration of palliative care for hematologic malignancies","authors":"Neha Kayastha , Alison R. Kavanaugh , Jason A. Webb , Thomas W. LeBlanc","doi":"10.1016/j.currproblcancer.2023.101011","DOIUrl":"10.1016/j.currproblcancer.2023.101011","url":null,"abstract":"<div><p><span><span>Specialist palliative care<span> provides additional support to facilitate living well with a serious illness, like cancer, even while pursuing disease-directed therapy. For patients with hematologic malignancies, integrated specialist palliative care improves symptom burden, mood, and </span></span>quality of life<span>, with benefits even extending to caregivers. Despite this, patients with hematologic malignancies continue to have significant unmet palliative care needs and typically access palliative care late in their disease trajectories, if at all. In this paper, we will define specialist palliative care and review its benefits for patients with hematologic malignancies. We will discuss the unmet palliative care needs of this patient population and the barriers to integrating palliative care and oncologic care. Finally, we will explore innovations and areas of future research to enhance and optimize palliative care integration into usual cancer care treatment for patients with hematologic malignancies. We will explore the importance of ongoing </span></span>clinical trials<span> that are examining the correct “dose” of palliative care; the use of technology and telehealth; and the use of novel treatments for this patient population. Together, we will consider innovative avenues to provide palliative care to patients with hematologic malignancies and their caregivers.</span></p></div>","PeriodicalId":55193,"journal":{"name":"Current Problems in Cancer","volume":"47 5","pages":"Article 101011"},"PeriodicalIF":2.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10278957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Practical considerations for prognostic communication in pediatric cancer 儿童癌症预后沟通的实际考虑。

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-10-01 DOI: 10.1016/j.currproblcancer.2023.101009

Brittany Cowfer , Tammy I. Kang , Matthew T. McEvoy

引用次数: 0

Information for Readers 读者资讯

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-10-01 DOI: 10.1016/S0147-0272(23)00082-X

引用次数: 0

Creating a culture for change: Lessons from behavioral economics and complexity science to increase serious illness conversations for patients with cancer 创造变革文化：从行为经济学和复杂性科学中汲取经验教训，增加癌症患者的严重疾病对话。

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-10-01 DOI: 10.1016/j.currproblcancer.2023.101020

Ramy Sedhom , Jasmine Tomita-Barber , Christopher R. Manz , Ravi B Parikh , Arjun Gupta , Qasim Hussaini , David Dougherty

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Barriers, blocks, and barricades: Disparities to access of palliative care in cancer care 障碍、阻碍和障碍:癌症治疗中获得姑息治疗的差异

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-10-01 DOI: 10.1016/j.currproblcancer.2023.101024

Sonia Malhotra , Michelle Christopher , Rajasree Pia Chowdry , Brenna Mossman , Amanda Cooke , Josh Deblieux , Cameron Simmons , Kiondra Fisher , Jason Webb , Michael Hoerger

{"title":"Barriers, blocks, and barricades: Disparities to access of palliative care in cancer care","authors":"Sonia Malhotra , Michelle Christopher , Rajasree Pia Chowdry , Brenna Mossman , Amanda Cooke , Josh Deblieux , Cameron Simmons , Kiondra Fisher , Jason Webb , Michael Hoerger","doi":"10.1016/j.currproblcancer.2023.101024","DOIUrl":"10.1016/j.currproblcancer.2023.101024","url":null,"abstract":"<div><p>Palliative care<span> (PC) is specialized medical care for people living with a serious illness. PC models have stressed pain and symptom management, communication that is patient- and family-centric and longitudinal support for families living with serious illness that is contiguous across multiple settings. Despite the benefits that PC provides from a patient, family and quality of care standpoint, several barriers and disparities exist. Included in these barriers are the lack of geographic access to PC programs as well as the focus on inpatient, hospital-based PC programs versus outpatient and home-based models. Workforce shortages, challenges with defining and designing PC, and racial, cultural and language barriers have all contributed to disparities within PC.</span></p><p>This review article outlines PC disparities including geographic access challenges, cross-cultural barriers and symptom and communication specific disparities. We discuss the impact these inequities have on patients living with cancer.</p></div>","PeriodicalId":55193,"journal":{"name":"Current Problems in Cancer","volume":"47 5","pages":"Article 101024"},"PeriodicalIF":2.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135810157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrated dual training in palliative care and oncology 姑息治疗和肿瘤学的综合双重培训

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-10-01 DOI: 10.1016/j.currproblcancer.2023.101012

Kathryn DeCarli , Rachel Rodenbach , Ramy Sedhom , Jamie Von Roenn , Briana Ketterer

{"title":"Integrated dual training in palliative care and oncology","authors":"Kathryn DeCarli , Rachel Rodenbach , Ramy Sedhom , Jamie Von Roenn , Briana Ketterer","doi":"10.1016/j.currproblcancer.2023.101012","DOIUrl":"10.1016/j.currproblcancer.2023.101012","url":null,"abstract":"<div><p><span>Fellowship training in Hospice and Palliative Medicine (HPM) and Hematology/Oncology (Hem/Onc) share common themes and roots in the </span>holistic care of people living with cancer. As of 2021, approximately 630 physicians in the United States were board-certified in both HPM and Hem/Onc. There is increasing demand for an integrated fellowship pathway, and the inaugural integrated fellowship Match took place in 2022. We present the historical context of the overlap in HPM and Hem/Onc fellowship training, limitations of the standard training paradigm, and an overview of the recently developed integrated training pathway accredited by the Accreditation Council for Graduate Medical Education (ACGME). We explore applications of dual training in clinical care, program development, and research at the intersection of HPM and Hem/Onc. Finally, we consider challenges to the success and how best to assess the outcomes of this program. Integrated fellowship training in HPM and Hem/Onc is 1 avenue to develop a cohort of dual-trained physicians poised to effect broad cultural change in this important and evolving space. A subset of physicians with dual training has the potential to fill unmet needs by promoting enhanced patient-centered care, developing infrastructure for heightened collaboration between these distinct but closely related fields, and prioritizing research focused on advanced communication skills and symptom management for patients with cancer.</p></div>","PeriodicalId":55193,"journal":{"name":"Current Problems in Cancer","volume":"47 5","pages":"Article 101012"},"PeriodicalIF":2.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10317052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Title Page 标题页

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-10-01 DOI: 10.1016/S0147-0272(23)00081-8

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Innovations and Opportunities for the Integration of Palliative Care in Cancer Care 癌症姑息治疗整合的创新与机遇。

IF 2.6 4区医学

Current Problems in Cancer Pub Date : 2023-10-01 DOI: 10.1016/j.currproblcancer.2023.101016

Kristina B. Newport , Jason A. Webb

引用次数: 0