The role of coenzyme Q10 as a preventive and therapeutic agent for the treatment of cancers

IF 2.5 4区医学 Q3 ONCOLOGY

Current Problems in Cancer Pub Date : 2024-02-01 DOI:10.1016/j.currproblcancer.2024.101063

Ghazal Ghasempour Dabaghi , Mehrdad Rabiee Rad , Mahtab Mohammad-Zamani , Atieh Karimi Shervedani , Farnaz Bahrami-Samani , Kiyan Heshmat-Ghahdarijani

引用次数: 0

Abstract

Currently, several options are available for the prevention and treatment of cancers; however, many limitations remain with these approaches. Recently, antioxidants have become important preventive and therapeutic alternatives with few adverse events and minimum cost. Coenzyme Q10 (CoQ10) is a naturally occurring component that performs an anticancer function by reducing oxidative stress. CoQ10 supplementation as an adjuvant therapy offers more progress in the elimination and development of cancers. This review aimed to critically assess and summarize the implication of CoQ10 in cancers, highlighting possible mechanisms, and future directions of research for the standardization of the current regimen for cancer prevention and treatment.

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辅酶 Q10 在癌症预防和治疗中的作用。

目前，有几种预防和治疗癌症的方法可供选择，但这些方法仍存在许多局限性。最近，抗氧化剂已成为重要的预防和治疗替代品，其不良反应少，成本最低。辅酶 Q10（CoQ10）是一种天然成分，可通过减少氧化应激发挥抗癌作用。补充辅酶Q10作为一种辅助疗法，可在消除癌症和防止癌症发展方面取得更多进展。这篇综述旨在批判性地评估和总结 CoQ10 对癌症的影响，强调可能的机制和未来的研究方向，以规范当前的癌症预防和治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Problems in Cancer 医学-肿瘤学

CiteScore

5.10

自引率

0.00%

发文量

审稿时长

15 days

期刊介绍： Current Problems in Cancer seeks to promote and disseminate innovative, transformative, and impactful data on patient-oriented cancer research and clinical care. Specifically, the journal''s scope is focused on reporting the results of well-designed cancer studies that influence/alter practice or identify new directions in clinical cancer research. These studies can include novel therapeutic approaches, new strategies for early diagnosis, cancer clinical trials, and supportive care, among others. Papers that focus solely on laboratory-based or basic science research are discouraged. The journal''s format also allows, on occasion, for a multi-faceted overview of a single topic via a curated selection of review articles, while also offering articles that present dynamic material that influences the oncology field.