Depression and Anxiety最新文献

{"title":"Perceived Disinformation, Anxiety, and Depressive Symptoms in the Czech Population: Age-Specific Associations","authors":"Vaclav Moravec,&nbsp;Beata Gavurova,&nbsp;Martin Rigelsky,&nbsp;Michal Miovsky","doi":"10.1155/da/3938343","DOIUrl":"10.1155/da/3938343","url":null,"abstract":"<p>The main goal of the study was to examine the relationship between anxiety and depressive symptoms and the perception of disinformation in the Czech population. The research was performed on a sample of 2867 respondents. Analytical processing was carried out through quasi-Poisson regression analysis separately for the three age groups (aged 16–39, 40–64, and 65–90). The dependent variables were the GAD-7 (Generalised Anxiety Disorder) and PHQ-9 (Patient Health Questionnaire) total scores, measuring anxiety and depressive symptoms, respectively. The independent variables were represented by the subjective perception of exposure, severity of disinformation, and credibility of specific disinformation in the Czech Republic. The 11 narratives, verified by a fact-checking organisation, were examined, of which eight were disinformation claims and three were factual reports. The outcomes demonstrated that 69.3% of the population experienced no or minimal anxiety, 19.0% mild, 7.2% moderate, and 4.5% severe anxiety. In the case of depression, 43.0% of the population demonstrated minimal symptoms, 25.4% mild, 9.9% moderate, and 14.3% no symptoms. After Benjamini–Hochberg false-discovery-rate (FDR) adjustment, perceived exposure to disinformation remained positively associated with GAD-7 and PHQ-9 scores across all three age groups. Among the 66 narrative-specific tests, 20 of 33 GAD-7 associations and 17 of 33 PHQ-9 associations remained statistically significant after FDR correction. The retained associations varied by narrative and age group rather than indicating a uniform age gradient. Because the data are cross-sectional, these associations do not establish causal direction.</p>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13621817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Sectional and Longitudinal Associations Between Dietary Intake and Depressive Symptoms in Young South African Adults: The African-PREDICT Study","authors":"Esmé Jansen van Vuren,&nbsp;Adrienne O’Neil,&nbsp;Deborah N. Ashtree,&nbsp;Melissa M. Lane,&nbsp;Rebecca Orr,&nbsp;Marlien Pieters,&nbsp;Tertia van Zyl","doi":"10.1155/da/2938819","DOIUrl":"10.1155/da/2938819","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Introduction&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Depression is highly prevalent among young adults worldwide. While research links health behaviours, such as dietary intake, to depression, few studies have examined these associations in low- and middle-income countries (LMICs), including South Africa. This study investigated whether dietary intake was associated with risk of depression in a cohort of young South African adults, aged 20–30 years, as part of the Global burden of disease Lifestyle And mental Disorder (GLAD) project.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This 5-year prospective cohort study was conducted in the North West Province of South Africa following the GLAD project protocol (DERR1-10.2196/65576). Dietary exposures were evaluated using three non-consecutive 24-h dietary recalls, measuring daily intake of food groups and nutrients defined by the GBD study. Depression outcomes were assessed at baseline (&lt;i&gt;n&lt;/i&gt; = 1039) and follow-up (&lt;i&gt;n&lt;/i&gt; = 551) using the Patient Health Questionnaire (cut-off ≥10). Logistic and Poisson regression analyses were performed, reporting odds ratios (ORs) and relative risks (RRs). Four models were tested: unadjusted, sociodemographic-adjusted, total energy (TE) intake-adjusted and fully adjusted (both sociodemographic and TE-adjusted). For longitudinal analyses, baseline depression cases were additionally excluded (&lt;i&gt;n&lt;/i&gt; = 403).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Participants (mean age 24.55 years; 51.4% female; 48.6% Black) had a 29.45% baseline depression prevalence. Higher milk intake was associated with a lower risk of incident depression (RR = 0.94, 95% CI 0.91–0.98) in the TE-adjusted model. Cross-sectionally, higher sugar-sweetened beverage consumption was associated with higher odds of depression, whereas higher calcium (OR = 0.48, 95% CI: 0.31, 0.76) and vegetable intake (OR = 0.74, 95% CI: 0.61, 0.91) were associated with lower odds after TE adjustment. Higher fibre intake was associated with lower odds in the unadjusted model.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Higher milk intake was associated with lower incident depression, while higher calcium, vegetable and fibre intake were associated with lower depression prevalence, but not when adjusting for sociodemographic information. These findings suggest that sociodemographic context should be considered alongside dietary strategies to support prevention efforts for common mental disorders in young adults.&lt;/p&gt;\u0000 \u0000 &lt;p&gt;&lt;b&gt;Trial Registration:&lt;/b&gt; ClinicalTrials.gov identifier: NCT03292094&lt;/p&gt;\u0000 ","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13624545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149118715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual Sensory Impairment and Depressive Symptoms: Association and Pathways in Three Cohorts and a Meta-Analysis","authors":"Ping Ni,&nbsp;Li Liu,&nbsp;Li Zeng,&nbsp;Meiling Ge,&nbsp;Fang Wang,&nbsp;Xiuying Hu","doi":"10.1155/da/8488263","DOIUrl":"10.1155/da/8488263","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The overall impact of dual sensory impairment (DSI) on depressive symptoms and its underlying mechanisms remains unclear, particularly across different culture contexts. This study aimed to examine the association between DSI and depressive symptoms in three distinct populations while exploring the mediating roles of social engagement and cognitive function.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Participants were recruited from three aging cohorts: the China Health and Retirement Longitudinal Study (CHARLS), the Health and Retirement Study (HRS), and the English Longitudinal Study of Ageing (ELSA). Harmonized survey wave data (2011/2012, 2015/2016, and 2018) were analyzed. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D), and DSI was defined based on self-reported hearing and vision impairments. To address potential confounding, logistic regression models were adjusted for demographic, lifestyle, and health factors. Mediation analyses were conducted using the PROCESS Macro (model 4) to examine the roles of social engagement and cognitive function. Furthermore, a meta-analysis was performed by integrating the results of the present study with those from previous cohort studies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study included 19,310 participants from the three cohorts. Separate analyses showed that DSI was significantly associated with higher odds of depressive symptoms across these cohorts (odds ratio [OR] = 1.24, 95% confidence interval [CI] = 1.15–1.33 in CHARLS; OR = 2.04, 95% CI = 1.78–2.31 in HRS; OR = 2.40, 95% CI = 1.79–3.00 in ELSA). A meta-analysis confirmed this association (OR = 1.73 and HR = 1.30). This relationship was partially mediated by reduced social engagement (2.31%–6.35%) and cognitive decline (5.72%–14.00%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>DSI is consistently associated with depressive symptoms in middle-aged and older adults across China, the United States, and England. Both reduced social engagement and cognitive decline significantly mediated this association, with comparable effect sizes. The mediation effects are largely robust, with instability observed only in one sensitivity analysis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13624546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149118804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Descriptive Epidemiology of Panic Attacks and Panic Disorder in Australia 2020–22: Prevalence, Correlates, Age of Onset and Changes Over Time","authors":"Matthew Sunderland,&nbsp;Sam Jones,&nbsp;Amelia Henry,&nbsp;Cath Chapman,&nbsp;Andrew Baillie,&nbsp;Tim Slade","doi":"10.1155/da/9977134","DOIUrl":"10.1155/da/9977134","url":null,"abstract":"<p>Panic disorder is highly debilitating and contributes a significant amount to anxiety-related disability-adjusted life years globally. To understand this burden, the current study provides an up-to-date understanding of the descriptive epidemiology of panic attacks and panic disorder in the Australian population. Data were from the most recent 2020–2022 National Survey of Mental Health and Wellbeing, a large-scale population-based study conducted in Australian households with respondents aged 16–85 years of age (<i>n</i> = 15,893). Panic attacks and panic disorder experienced across the lifetime, within the past 12 months and within the past 30-days were assessed by the Composite International Diagnostic Interview according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) diagnostic criteria to facilitate direct comparisons with the 2007 National Survey of Mental Health and Wellbeing (<i>n</i> = 8841). The lifetime prevalence of panic attacks and panic disorder was ~27% and 4%, respectively. Those with panic disorder indicate a median age of onset in their early 20s and the experience of panic disorder is not trivial, with nearly half of all cases (45%) falling within the ‘severe’ range in terms of severity and functional impairment. There were significantly elevated odds in select subgroups of the population with evidence that panic attacks and panic disorder remain a pressing concern for the Australian population, and particularly so in 2020–22 for younger cohorts (16–24), females, those who have never been married, and people who reside in inner regional areas. Despite improvements in access to mental health services, there remains a strong need for improved mental health services and targeted prevention programmes.</p>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13617539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Trajectories of Grief Before and After Bereavement and Their Association With Mental Health Outcomes: A Pilot Prospective Cohort Study From the China Grief Cohort 2025","authors":"Chunfeng Xiao,&nbsp;Song Wan,&nbsp;Xinpeng Xu,&nbsp;Wentao Yao,&nbsp;Yufei Wang,&nbsp;Jing Wei","doi":"10.1155/da/5274616","DOIUrl":"10.1155/da/5274616","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Prolonged grief disorder (PGD) impairs psychophysiological well-being and social functioning. Although post-death grief trajectories have been well-documented, pre-death grief trajectories remain understudied, particularly within the same cohort.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This exploratory pilot study aimed to identify candidate longitudinal trajectories of grief before and after bereavement and to examine their associations with subsequent mental health outcomes, with the goal of generating hypotheses to inform a larger confirmatory cohort.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This prospective cohort study was conducted at Peking Union Medical College Hospital. Participants were adult immediate family members of terminally ill patients with a life expectancy of 6 months or less enrolled between October and December 2023. Grief, depression, anxiety and stress were measured using the Anticipatory Grief Scale (AGS) and the PGD-13 Revised (PG-13-R), the 17-item Hamilton Rating Scale for Depression (HAMD-17), the Hamilton Anxiety Scale (HAMA) and the Impact of Event Scale-Revised (IES-R), at baseline, monthly before bereavement and quarterly for 6 months after bereavement, respectively.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A total of 60 participants (mean [SD] age, 52.82 [10.18%] years; 32 [53.3%] women) were enrolled, most were offspring of terminally ill patients (44 [73.3%]). Two pre-death grief trajectories (Low, &lt;i&gt;n&lt;/i&gt; = 51 [85%]; and increasing, &lt;i&gt;n&lt;/i&gt; = 9 [15%]) and four post-death grief trajectories (high/decreasing, &lt;i&gt;n&lt;/i&gt; = 9 [15%]; moderate/decreasing, &lt;i&gt;n&lt;/i&gt; = 26 [43.33%]; low/decreasing, &lt;i&gt;n&lt;/i&gt; = 15 [25%]; and high/prolonged, &lt;i&gt;n&lt;/i&gt; = 10 [16.67%]) were identified. At the final visit, the incidences of PGD, depressive disorders, anxiety disorders and stress-related disorders were 16.7%, 16.7%, 30.0% and 0%, respectively. Participants in the Increasing pre-death grief trajectory and the persistently high/prolonged post-death grief trajectory had higher incidences of PGD, depressive disorders, and anxiety disorders compared to other groups.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Individuals experiencing increasing pre-death grief or persistently high-level post-death grief are more likely to develop PGD and other mental disorders. Findings are exploratory and require replication in a larger, theoretically informed cohort.&lt;/p&gt;\u0000 \u0000 ","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Moderating Role of Trait Anxiety in the Relationship Between Acute Aerobic Exercise and Cognitive Control in College Students","authors":"Zongyu Yang,&nbsp;Xiaoming Liu,&nbsp;Yi Tang,&nbsp;Long Yin,&nbsp;Fang Li","doi":"10.1155/da/1381460","DOIUrl":"10.1155/da/1381460","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to introduce trait anxiety as an individual-difference factor and further examine the complex relationship between acute aerobic exercise and cognitive control in college students.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A mixed experimental design was adopted. Trait anxiety was assessed using the State-Trait Anxiety Inventory (STAI) and used to classify participants into high- and low-trait-anxiety groups. Cognitive control was measured with the AX continuous performance task (AX-CPT). The intervention conditions consisted of 20 min of seated rest and moderate-intensity acute aerobic exercise. A 2 (intervention: acute aerobic exercise vs. rest) × 2 (time: pretest vs. posttest) × 2 (trait anxiety: high vs. low) repeated-measures analysis of variance (ANOVA) was conducted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Only participants with high trait anxiety showed a significant reduction in posttest reaction time on BX trials, an index of proactive control, following acute aerobic exercise (<i>p</i> &lt; 0.001), with no significant change in accuracy (<i>p</i> &gt; 0.050). In addition, the proactive behavioral index (PBI) for error rate [PBI(error)] significantly increased in this group after exercise (<i>p</i> = 0.031). No significant changes were observed in <i>d</i>′(Proactive), A-cue bias, PBI(RT), PBI(composite), or indices of reactive control under any intervention condition. Among participants with low trait anxiety, neither intervention produced significant changes in proactive control, as reflected by BX trials, or reactive control, as reflected by AY trials and <i>d</i>′(Reactive) (all <i>p</i><i>s</i> &gt; 0.050).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Trait anxiety exerted a significant influence on the relationship between acute aerobic exercise and cognitive control, with this effect being particularly evident in reaction time during proactive control. These findings suggest that future exercise interventions should incorporate individuals’ baseline cognitive control characteristics to develop more precise and individualized exercise prescriptions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13617466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Activity Volume, Exercise Guidance, and Depressive Symptoms in Young-Old Adults: The Role of Internet Use Frequency and Self-Perceived Digital Proficiency","authors":"Yue-Xuan Mu,&nbsp;Fang-Zhou Qian,&nbsp;Juan Cui","doi":"10.1155/da/7595212","DOIUrl":"10.1155/da/7595212","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Physical activity is associated with depressive symptoms in later life, but this association may depend on the form of exercise-related support and older adults’ digital engagement. This study examined whether physical activity volume (PAV) and exercise guidance (EG) were associated with depressive symptoms among young-old adults in China and whether these associations varied by internet use frequency (IUF) and self-perceived digital proficiency.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data were drawn from the 2020 to 2023 waves of the China Longitudinal Aging Social Survey (CLASS). The analytic sample included 5643 adults aged 60–75 years. Generalized estimating equations (GEE) were used to examine the associations of PAV and EG with depressive symptoms, as well as their interactions with IUF and self-perceived digital proficiency.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>PAV and EG were associated with lower depressive symptom scores in the full sample, although the association for PAV was less consistent across subgroup and moderation models. More frequent internet use was associated with lower depressive symptom scores and was more consistently related to the EG—depressive symptoms association than to the PAV—depressive symptoms association. The interaction between PAV and IUF was evident mainly among rural respondents. Among internet users, high self-perceived digital proficiency was associated with lower depressive symptom scores and showed a clearer conditional association with EG than with PAV.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Digital engagement was more consistently related to the depressive-symptom relevance of EG than to PAV itself. These findings suggest that supporting young-old adults’ mental health may require attention not only to physical activity levels but also to accessible EG and age-friendly digital support.</p>\u0000 </section>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13618808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathways From Cyber Victimization to Adolescent Depression: A Latent Profile and Bridge Network Analysis","authors":"Ergün Kara,&nbsp;Halil Aslan","doi":"10.1155/da/3544219","DOIUrl":"https://doi.org/10.1155/da/3544219","url":null,"abstract":"<p>Cyber victimization is among the most consistent predictors of depression (DEP) in adolescence, yet research has largely treated both constructs as unidimensional totals, obscuring which specific victimization experiences activate which depressive symptoms and for whom. This study applied a person-centered and network psychometric approach to map these pathways in a cross-sectional community sample of 622 Turkish adolescents (55.0% female; <i>M</i>_aɡe = 13.90 years). Latent profile analysis (LPA) identified three distinct subgroups based on self-esteem (SE), family affluence, and social media (SM) use: a low SE/moderate SM group (<i>n</i> = 395, 63.5%), a high SE/high DEP group (<i>n</i> = 115, 18.5%), and a high SM use group (<i>n</i> = 112, 18.0%). Depressive symptom networks differed significantly in global strength across profiles; the high SM use group showed the densest intersymptom connections. A bipartite bridge network analysis revealed that self-harm/suicidal ideation was the strongest cross-community bridge node (bridge expected influence = 0.143), despite being the most peripheral symptom within the DEP network itself. This dissociation suggests that the symptom is linked mainly to cyber victimization rather than to other depressive symptoms. Embarrassing messages was the strongest victimization-side bridge node (EI = 0.095). These findings challenge the assumption that intranetwork centrality predicts intervention priority: Peripheral symptoms may function as critical entry points when external stressors drive activation.</p>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/3544219","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149048439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Psychodynamic Psychotherapy for Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","authors":"Max Moser,&nbsp;Angela Barrett,&nbsp;Christian. F. J. Woll-Weber,&nbsp;Peter Fonagy,&nbsp;Patrick Luyten,&nbsp;Chloe Campbell","doi":"10.1155/da/6172409","DOIUrl":"10.1155/da/6172409","url":null,"abstract":"<p>This pre-registered systematic review and meta-analysis (PROSPERO CRD42023490547) evaluated the effectiveness of long-term psychodynamic psychotherapy (LTPP) in reducing depressive symptoms using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework and updated empirically supported treatment (EST) criteria. MEDLINE, PsycINFO, Embase, and the Cochrane Central Register of Controlled Trials were searched through January 16, 2025. Sixteen randomized controlled trials involving 1992 participants met inclusion criteria (LTPP ≥9 months, ≥30 sessions), encompassing varied populations, psychodynamic modalities, and comparator conditions. Effects were pooled using two- or three-level random-effects models. Risk of bias was assessed using Cochrane RoB 2. At treatment completion, LTPP showed significant reductions in depressive symptoms compared to all comparators (SMD = 0.34, 95% CI [0.20, 0.47]) and to active treatments specifically (SMD = 0.27, 95% CI [0.1, 0.45]). Effects were generally sustained at follow-up. Subgroup analyses revealed larger effects when LTPP was compared to active controls (SMD = 0.61), but with greater heterogeneity and very low certainty of evidence. GRADE assessments indicated high-certainty evidence for depressive symptom outcomes in the all-trials condition and moderate-certainty evidence in comparisons with active treatments. According to updated EST criteria, these findings support a Strong recommendation for LTPP in reducing depressive symptoms. However, limited evidence on functional outcomes, economic impact, and long-term maintenance precluded a Very Strong recommendation. Evidence from comparisons with active controls was of very-low certainty, supporting only a Weak recommendation. Risk of bias was a concern in most studies. Moderator analyses were prevented by small study numbers. Future individual patient data meta-analyses are needed to identify predictors of treatment response and to establish which subgroups of patients with depression are most suitable candidates for LTPP. Funding: Royal Australian and New Zealand College of Psychiatrists.</p>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13601849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149042239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Depression and Its Association With Gallstones: Evidence From NHANES With Exploration of Mediating Pathways","authors":"Enyang He,&nbsp;Yaoqun Wang,&nbsp;Guilin Nie,&nbsp;Qingyan Kong,&nbsp;Yu Teng,&nbsp;Di Zeng,&nbsp;Jiaqi Yang,&nbsp;Xinming Li,&nbsp;Fei Liu,&nbsp;Geng Liu,&nbsp;Bei Li,&nbsp;Nansheng Cheng","doi":"10.1155/da/1800832","DOIUrl":"10.1155/da/1800832","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to analyze long-term trends (2005–2023) in the prevalence of depression among US adults and to specifically investigate the association between depression and gallstone disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data from multiple cycles of the National Health and Nutrition Examination Survey (NHANES) were utilized. Depression was assessed using the patient health questionnaire-9 (PHQ-9), and gallstone status was determined by self-reported physician diagnosis. Weighted logistic regression models were employed to evaluate the association between depression and gallstones, with multivariable-adjusted models controlling for potential confounders. Furthermore, dose–response relationship analysis and mediation analysis were conducted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Between 2005 and 2023, the prevalence of depression among US adults demonstrated a significant increasing trend. In the 2017–2023 data, depression was significantly associated with higher odds of gallstones (odds ratio [OR] = 1.61, 95% confidence interval [CI]: 1.13–2.29). Dose–response analysis revealed a positive association between increasing PHQ-9 scores and gallstone presence (<i>p</i> for trend &lt;0.001). Mediation analyses suggested that smoking and obesity explained ~6.3% and 6%, respectively, of the total observed association between depression and gallstones.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study highlights a rising trend in the prevalence of depression and provides evidence for an association between depression and gallstone disease. The association appears to be partially mediated by smoking and body mass index (BMI). These findings underscore the clinical importance of considering gallstone screening and implementing integrated health management strategies for individuals with depression, while further longitudinal studies are warranted to clarify the temporal direction of this relationship.</p>\u0000 </section>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2026 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13595807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149026828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}