Health Psychology最新文献

{"title":"Communal coping in type 1 diabetes: Randomized trial of a couple-focused intervention.","authors":"Vicki S Helgeson","doi":"10.1037/hea0001614","DOIUrl":"https://doi.org/10.1037/hea0001614","url":null,"abstract":"<p><strong>Objective: </strong>A great deal of observational research has demonstrated links of communal coping to good relationship and health outcomes among people with chronic disease and their partners. However, there has not been a strong empirical test of a communal coping intervention with the goal of affecting these outcomes. In this study, we developed a couples' intervention for adults with type 1 diabetes based on communal coping-adopting a shared appraisal of diabetes and collaborating with a partner to manage diabetes.</p><p><strong>Method: </strong>We recruited 80 persons (July 2023 to January 2025) with type 1 diabetes (PWD) and their partners and randomly assigned them to intervention or usual care control conditions. The intervention consisted of a single 2-hr session with 7-days of follow-up intervention reminders. There was a baseline assessment and a 6-week follow-up assessment in which primary outcomes (self-care behavior, diabetes distress) and secondary outcomes (relationship quality, life satisfaction, depressive symptoms, time in target glucose range, hemoglobin A1c) were assessed. In addition, abbreviated outcome measures were assessed at the end of the day during a 14-day daily diary session that immediately followed the baseline session.</p><p><strong>Results: </strong>The intervention enhanced perception of communal coping among both PWD and partners, as evidenced in both survey and daily diary reports. However, the intervention did not have significant effects on primary or secondary outcomes, with the exception of an increase in time in target glucose range and an increase in daily diary reports of relationship quality.</p><p><strong>Conclusions: </strong>Conceptual and methodological explanations for these findings are discussed. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of plain cigarette packaging on point-of-sale purchasing behavior among young adults who smoke.","authors":"Steven C Martino, Michael S Dunbar, Claude M Setodji, Desmond Jenson, Maggie Hieber, William G Shadel","doi":"10.1037/hea0001601","DOIUrl":"10.1037/hea0001601","url":null,"abstract":"<p><strong>Objective: </strong>This experiment evaluated how full versus partial plain cigarette packaging, compared with fully branded packaging, affects young adult smokers' cigarette purchasing and motivation to quit smoking in a simulated retail point-of-sale environment.</p><p><strong>Method: </strong>The experiment took place in the RAND StoreLab, a life-sized replica of a convenience store. Smokers (<i>N</i> = 433) aged 21-34 years were randomly assigned to shop in one of three store conditions: (a) a <i>status quo</i> condition, featuring a typical U.S. tobacco power wall; (b) a <i>full coverage</i> condition, where cigarette packages were fully standardized in a uniform brown-green color; or (c) a <i>half coverage</i> condition, where only the top half of packages were standardized. Cigarette purchases were tracked, and participants completed measures of motivation to quit smoking pre- and postshopping. Logistic regression was used to examine condition effects on these outcomes.</p><p><strong>Results: </strong>Participants in the full coverage condition were significantly less likely to purchase cigarettes than those in the status quo condition, adjusted <i>OR</i> = 0.54, <i>p</i> = .04. In contrast, the half coverage condition had no effect on cigarette purchasing, adjusted <i>OR</i> = 0.96, <i>p</i> = .88. Neither the full coverage nor the half coverage condition significantly affected motivation to quit smoking, <i>p</i>s = .53 and .64, respectively.</p><p><strong>Conclusions: </strong>This study provides novel experimental evidence in support of full plain packaging as a means to further reduce cigarette purchasing in the United States. The lack of an effect of partial plain packaging suggests that this option may not be a sufficient means of regulation. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13143334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147823767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Joint association of loneliness and traditional risk factor control and the risk of cardiovascular-kidney-metabolic syndrome progression: A national prospective cohort study.","authors":"Yu-Hua Liu, De-Feng Zhao, Rong-Rui Huo, Lu Zhai","doi":"10.1037/hea0001613","DOIUrl":"https://doi.org/10.1037/hea0001613","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine the prospective associations of loneliness and social isolation with the risk of Cardiovascular-Kidney-Metabolic Syndrome Stages 0-3 progression to cardiovascular disease (CVD) and to compare the relative importance of loneliness and social isolation with traditional risk factors. In addition, the interactions of loneliness or isolation with the degree of risk factor control in relation to CVD risk were evaluated.</p><p><strong>Method: </strong>This national prospective cohort study included 3,500 participants from the China Health and Retirement Longitudinal Study. Loneliness and social isolation were self-reported. The degree of risk factor control was defined as the number of glycated hemoglobin (HbA1c), blood pressure, low-density lipoprotein cholesterol, smoking, and kidney condition controlled within the target range. Cox proportional hazards models and interaction analyses were used to estimate risk for CVD.</p><p><strong>Results: </strong>Of the 3,500 participants (<i>M</i>_age [<i>SD</i>] = 58.58 [8.72] years), 1,615 (45.1%) were men. Over a median follow-up of 7.1 years, 714 participants developed CVD. Loneliness, but not social isolation, was independently associated with increased CVD risk (adjusted hazard ratio = 1.25, 95% confidence interval [1.02, 1.52]. Loneliness ranked fourth among predictors, following low-density lipoprotein cholesterol, systolic blood pressure, and body mass index. Joint analysis showed that individuals who were lonely and had a low risk factor control had the highest CVD risk (hazard ratio = 1.91, 95% confidence interval [1.43, 2.54], with significant additive and multiplicative interactions.</p><p><strong>Conclusions: </strong>Loneliness, but not social isolation, is associated with a higher risk of cardiovascular-kidney-metabolic syndrome progression to CVD and shows an interaction with the degree of risk factor control. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147823754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dyadic patterns of abstinence from smoking in dual-smoking couples enrolled in a pilot randomized clinical trial.","authors":"Fernanda C Andrade, Ye Shen, James M MacKillop, Steven R H Beach, Michelle R vanDellen","doi":"10.1037/hea0001573","DOIUrl":"10.1037/hea0001573","url":null,"abstract":"<p><strong>Objective: </strong>Despite the positive role of social relationships in behavior change, dyadic interventions for smoking have not been consistently successful. This owes, in part, to the fact that dual-smoking cohabiting couples share similar routines, environments, and relational dynamics that can undermine quitting efforts. We adopted an exploratory and descriptive approach to identify distinct profiles of smoking abstinence within dyads, how relationship dynamics relate to these patterns, and whether these patterns predict smoking status at follow-up.</p><p><strong>Method: </strong>We utilized preexisting data from a pilot RCT examining the effects of partner-involved financial incentives on dyadic abstinence. Both members of 95 dual-smoking couples (52% female, 73% White, <i>M</i>_age = 42.39, <i>SD</i> = 10.57) recruited between 2021 and 2022 provided baseline information about their relational and motivational dynamics, followed by 10 weeks of daily reports of smoking behavior, and biochemically verified quit status at follow-up.</p><p><strong>Results: </strong>Latent growth mixture models suggested four patterns of dyadic abstinence: Concordant abstainers, Discordant abstainers, Discordant nonabstainers, and Concordant nonabstainers. Treatment arm and motivational and relational dynamics predicted the probability of following specific dyadic patterns of behavior change, and dyadic patterns of change predicted individual and couple quitting status at follow-up.</p><p><strong>Conclusions: </strong>Our findings underscore the importance of considering that treatment will facilitate coordinated dyadic behavior change for some couples but not all and emphasize the need to better understand when and how mechanisms support long-term abstinence. More work is needed to investigate whether these patterns generalize across samples with more diverse sociodemographic and health characteristics. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":"528-538"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12857745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146088168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social identity processes affect objectively measured physical health: A systematic review and meta-analyses.","authors":"Tegan Cruwys, Mark Stevens, Niklas K Steffens, Jan A Häusser, Samantha M Pang, Miranda Cody-Osborne, Ella Edwards-Smith, Eoin Garton, Yuang Cheng, Taylah McCluskey","doi":"10.1037/hea0001552","DOIUrl":"10.1037/hea0001552","url":null,"abstract":"<p><strong>Objective: </strong>A systematic review (CRD42023422237) examined the effect of social identity processes on objectively measured physical health.</p><p><strong>Method: </strong>Eligible studies (a) quantitatively manipulated or measured social identity strength, salience, or threat, or multiple group membership, and (b) objectively measured (i.e., nonself-report) health behavior, physical health, or health-relevant biomarker. PsychINFO, PubMed, and SPORTDiscus were searched (24 September 2024). We conducted narrative synthesis, meta-analysis for sufficiently homogenous subclusters, and risk of bias assessment.</p><p><strong>Results: </strong>The 106 studies (<i>N</i>_total = 290,816; 20 countries; published 1982-2024) were highly diverse in design and dependent variables and were grouped into five discrete clusters. First, 46 studies assessed whether threats to social identities increased acute cardiovascular reactivity, <i>g</i> = 0.40, 95% confidence interval (CI) = [.179, .617] (42 effects, <i>N</i> = 1,432). Second, 21 studies assessed whether social identity salience reduced stress biomarkers, <i>g</i> = -0.28, 95% CI = [-.544, -.006] (20 effects, <i>N</i> = 487). Third, 16 studies (too heterogenous for meta-analysis) found evidence of ingroup normative influence on health behaviors. Fourth, six studies (too heterogenous for meta-analysis) assessed social identification in health interventions; five found benefits for disease-related outcomes. Finally, 17 studies examined the protective effect of subjective (multiple) group membership on long-term health (e.g., mortality), <i>OR</i> = .59, 95% CI = [.385, .891] (eight effects, <i>N</i> = 27,985). Studies were high quality on average, although there was some evidence of publication bias.</p><p><strong>Conclusion: </strong>Results provide evidence for both social cure and social curse predictions of the social identity approach to health. We identified five distinct ways in which social identity processes affect physical health. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":"497-527"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145379967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Situational awareness predicts self-management of type I diabetes in adolescents and young adults.","authors":"Paul F Cook, Emily Jost, Gregory Forlenza, Laurel H Messer, Solus Thompson, Evan Peck, Stephen Voida","doi":"10.1037/hea0001547","DOIUrl":"10.1037/hea0001547","url":null,"abstract":"<p><strong>Objective: </strong>Using a hybrid closed-loop system predicts higher time in target glucose range (TIR) for adolescents and young adults with type I diabetes (T1D). However, patients do not always use these systems effectively for self-management. Based on Two Minds Theory, we hypothesized that more automatic and proactive ways of interacting with the system would be associated with higher TIR, whereas more reactive responses to system prompts would not.</p><p><strong>Method: </strong>We recruited 20 patients with T1D from a diabetes clinic. Participants used the Tandem t:slim X2 with Control-IQ technology (Control-IQ) hybrid closed-loop system. For 2 weeks, they also completed daily surveys about T1D self-management, plus triggered surveys each time they interacted with Control-IQ about their reasons and perceived automaticity.</p><p><strong>Results: </strong>Proactive reasons for interacting with Control-IQ, such as planning to eat, predicted higher TIR. Reactive interactions, for example, responding to system alerts, did not. In fact, participants had higher TIR when they interacted less often with Control-IQ and administered fewer manual boluses. Self-reported automaticity did not predict TIR, but perceived self-management did. Suspecting high glucose was associated with higher TIR regardless of accuracy.</p><p><strong>Conclusions: </strong>Adolescents who interacted less intensively and more proactively with a hybrid closed-loop system had better glucose control. Accurate perception of glucose mattered less than believing one's glucose might be too high; it is possible that situationally aware participants detected increases before their glucose went out of range. Better measures of automaticity are needed. Hybrid closed-loop systems help adolescents and young adults self-manage T1D when used in a situationally aware way. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":"578-589"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12822998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life satisfaction and blood pressure: A coordinated analysis of 16 cohorts.","authors":"Yoobin Park, Laura D Kubzansky, Wendy Berry Mendes","doi":"10.1037/hea0001565","DOIUrl":"10.1037/hea0001565","url":null,"abstract":"<p><strong>Objective: </strong>Research suggests that high life satisfaction is related to better health outcomes, but its relationship with blood pressure, a key indicator of cardiovascular health, remains inconclusive. We conducted a comprehensive cross-sectional investigation of the association between life satisfaction and blood pressure.</p><p><strong>Method: </strong>We analyzed data from 16 cohorts, each including life satisfaction assessments and blood pressure measurements. We meta-analyzed associations between life satisfaction and (a) continuous levels of systolic and diastolic blood pressure and (b) presence of high blood pressure, inferred based on measured blood pressure of ≥140/90 mmHg and self-reported medication use. We also conducted parallel analyses, predicting hypertension status operationalized based solely on self-reported diagnosis and medication use, as in previous research. Finally, we examined the role of depressive symptoms in these relationships.</p><p><strong>Results: </strong>Meta-analytic results revealed no consistent association between life satisfaction and either measured blood pressure levels or the presence of high blood pressure. These associations did not differ by the type of life satisfaction measure used or by the economic conditions of the studied countries. However, when considering self-reported hypertension, higher life satisfaction was related to a lower hypertension risk, consistent with previous findings. More depressive symptoms were related to both lower measured blood pressure and a higher risk of self-reported hypertension.</p><p><strong>Conclusion: </strong>These findings highlight the importance of distinguishing between self-reported and objectively measured health outcomes when understanding and investigating the relationship between psychological and physical well-being. We discuss caveats in relying on single-day blood pressure assessments or recalled diagnoses to infer hypertension status. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":"484-496"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12704161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictions from early adolescent interpersonal aggression to accelerated aging in adulthood: Relational and biological mechanisms of linkage.","authors":"Joseph P Allen, Meghan A Costello, Gabrielle L Hunt, Bert N Uchino, Karen Sugden","doi":"10.1037/hea0001576","DOIUrl":"10.1037/hea0001576","url":null,"abstract":"<p><strong>Objective: </strong>This study examined early adolescent interpersonal aggression, subsequent conflict with parents, and aggression toward close peers as predictors of accelerated biological aging by age 30.</p><p><strong>Method: </strong>Participants (<i>N</i> = 123; 46 males and 75 females) were assessed repeatedly, along with parents and close friends, ages from 13 to 30.</p><p><strong>Results: </strong>Early adolescent interpersonal aggression was found to predict later accelerated aging even after accounting for adolescent gender, family income, prior health difficulties, and body shape ratings in adolescence. Path analyses suggested that the effects of early interpersonal aggression were potentially mediated via higher levels of father-adolescent conflict reported by fathers in adolescence and by aggressive behavior toward close peers as reported by those peers in early adulthood. Follow-up analyses suggested that these same factors also predicted adult body mass index scores after accounting for body shape in adolescence.</p><p><strong>Conclusions: </strong>Results are interpreted as evidence that social difficulties with lifelong health implications may be identified beginning in early adolescence, thus highlighting the potential importance of early interventions to address these difficulties. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":"473-483"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12970554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mindfulness for heart and mind: Mindfulness-based blood pressure reduction randomized clinical trial for depression symptoms.","authors":"Surenmaa Sukhbaatar, Shufang Sun, Matthew M Scarpaci, Vinicius V Neves, Margaret A Sheridan, Eric B Loucks","doi":"10.1037/hea0001568","DOIUrl":"10.1037/hea0001568","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the effects of the Mindfulness-Based Blood Pressure Reduction (MB-BP) program on depression symptoms in individuals with elevated blood pressure (BP). Exploratory analyses examined whether childhood abuse or neglect moderated these effects.</p><p><strong>Method: </strong>Adults with elevated BP (<i>n</i> = 201; ≥120/80 mmHg) were randomized to MB-BP (<i>n</i> = 101) or enhanced usual care (<i>n</i> = 100) and followed for 6 months. MB-BP trained participants in mindful self-regulation skills-self-awareness, attention control, and emotion regulation-and applied these skills to modifiable determinants of BP and depression symptoms, such as diet, physical activity, alcohol use, and stress reactivity. Depression symptoms were assessed using the Center for Epidemiologic Studies Depression Scale-Revised. Outcome assessors were blinded to group assignments.</p><p><strong>Results: </strong>Participants (58.8% female, 81.1% non-Hispanic White, mean age 59.5years) in the MB-BP group had a 1.65-point greater reduction in Center for Epidemiologic Studies Depression Scale-Revised scores at 6 months versus controls (95% CI [-2.79, -0.51], Cohen's <i>d</i> = 0.29). Exploratory analyses revealed sizable reductions in depression symptoms for participants exposed to high parental neglect (-2.25, 95% CI [-4.18, -0.31]) and modest reductions in those with low neglect (-0.78, 95% CI [-2.28, 0.70]), with a formal test for interaction <i>p</i> value of .011. High abuse exposure was associated with depression symptom improvements (-2.34, 95% CI [-4.58, -0.10]), as was low abuse exposure (-1.49, 95% CI [-4.08, 1.10]), with a test for interaction <i>p</i> value of .079.</p><p><strong>Conclusion: </strong>MB-BP significantly reduced depression symptoms in individuals with elevated BP, with preliminary evidence suggesting amplified benefits for those with early-life adversity, particularly neglect. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":"566-577"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social stressors and inflammatory gene expression in U.S. Chinese immigrants.","authors":"Carolyn Y Fang, Marilyn Tseng, Brian L Egleston, Amy H Auchincloss, Emily Walton, Steve W Cole","doi":"10.1037/hea0001577","DOIUrl":"10.1037/hea0001577","url":null,"abstract":"<p><strong>Objective: </strong>Immigrants comprise approximately 14% of the U.S. population and experience increasing rates of chronic disease after migration that are not wholly attributable to behavioral acculturation. The present study examined whether social stressors commonly experienced by immigrants (e.g., acculturative stress, discrimination) are associated with proinflammatory gene expression in a sample of Chinese immigrants residing in the United States.</p><p><strong>Method: </strong>Participants (<i>n</i> = 216) in an observational study completed assessments of acculturative stress, perceived discrimination, and social isolation. Participant weight and height were measured during an in-person exam, and fasting blood samples were collected and assayed for inflammatory gene expression.</p><p><strong>Results: </strong>Greater perceived discrimination was significantly associated with higher levels of inflammatory gene expression controlling for age, sex, body mass index, smoking status, and other demographic variables. Neither acculturative stress nor social isolation was associated with inflammatory gene expression profiles.</p><p><strong>Conclusions: </strong>This is one of the first studies to examine social stressors in relation to biologic pathways that may underlie the increase in chronic disease risk observed among foreign-born populations. These findings contribute to a more comprehensive understanding of how social experiences may impact immigrant health. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":"539-548"},"PeriodicalIF":3.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}