Annesa Flentje, Gowri Sunder, Adam W Carrico, Kesava Asam, Torsten B Neilands, Nadra E Lisha, James Dilley, Elena Flowers, Kord Kober, Bradley Aouizerat
{"title":"Differential gene expression in response to AWARENESS: A randomized controlled trial of an intersectional minority stress intervention.","authors":"Annesa Flentje, Gowri Sunder, Adam W Carrico, Kesava Asam, Torsten B Neilands, Nadra E Lisha, James Dilley, Elena Flowers, Kord Kober, Bradley Aouizerat","doi":"10.1037/hea0001451","DOIUrl":"10.1037/hea0001451","url":null,"abstract":"<p><strong>Objective: </strong>Past correlational research has shown that minority stress has direct and indirect effects on the biology of sexual minority people. This pilot randomized controlled trial (RCT) examined the potential of AWARENESS, a nine-session cognitive behavioral intervention to reduce intersectional minority stress, to alter gene expression related to immune function, inflammation, and HIV disease progression.</p><p><strong>Method: </strong>Between 2016 and 2019, 25 sexual minority men living with HIV with recent substance use (n = 12 in AWARENESS and n = 13 in control) were enrolled, a subset with complete gene expression data among the 41 individuals within the parent RCT. Blood samples were taken prior to the intervention, at the 9-week conclusion of the intervention, and at 4 months postrandomization, and leukocyte RNA was sequenced for all samples. The authors examined differential expression analyses of single genes and overrepresentation analysis of gene sets.</p><p><strong>Results: </strong>Neither AWARENESS nor the control condition was related to the differential expression of single genes. Overrepresentation analysis suggested that AWARENESS was related to changes over time in gene expression in leukocyte RNA in 52 gene sets (q < .05), many of which are related to immune function, while the active control condition was related to changes in gene expression among genes in only one gene set. When AWARENESS was compared to the control condition, four gene sets evidenced an overrepresentation of genes reflecting change over time.</p><p><strong>Conclusions: </strong>This RCT suggests that AWARENESS is associated with changes in gene expression, primarily focused on changes in genes associated with immune processes. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":"44 3","pages":"291-296"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael E Newcomb, Gregory Swann, Elizabeth L Addington, Kathryn Macapagal, Judith T Moskowitz, Elissa L Sarno, Sarah W Whitton, Brian Mustanski
{"title":"Randomized controlled trial of a relationship education and HIV prevention program for young male couples: Biomedical and behavioral outcomes.","authors":"Michael E Newcomb, Gregory Swann, Elizabeth L Addington, Kathryn Macapagal, Judith T Moskowitz, Elissa L Sarno, Sarah W Whitton, Brian Mustanski","doi":"10.1037/hea0001448","DOIUrl":"10.1037/hea0001448","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the efficacy of the 2GETHER relationship education and HIV prevention program for young male couples in reducing the risk for HIV.</p><p><strong>Method: </strong>We conducted a randomized controlled trial of 2GETHER relative to an attention-matched and highly active positive affect enhancement program for couples. We randomized 128 young male couples (N = 256) to 2GETHER or control from 2017 to 2021. Primary biomedical outcome (i.e., rectal chlamydia and gonorrhea) was measured at baseline and 12 months and self-reported condomless anal sex was measured every 3 months across 12-month follow-up. Secondary outcomes were other HIV prevention and risk behaviors, relationship functioning, and substance use. We used multilevel models in MPlus to account for clustering with dyads and within-person change over time. Effects of time (for self-reported outcomes) were modeled using latent growth curves at the between-couple level.</p><p><strong>Results: </strong>We observed no differences between conditions in outcomes, but there was a significant change in outcomes across 12 months. Rates of rectal sexually transmitted infections and self-reported condomless anal sex decreased significantly in both conditions. We also observed significant increases in HIV testing, improvement in relationship communication, and reduction in alcohol-related problems in both conditions across 12 months.</p><p><strong>Conclusion: </strong>Couples in both the 2GETHER and positive affect enhancement programs showed improvement in biomedical and behavioral indicators of HIV risk, as well as improvement in relationship communication, but without a treatment effect we cannot conclude improvement resulted from the interventions. Couple-based programs that promote connectedness, including relationship education and positive affect enhancement, have a strong potential to reduce young couples' HIV risk. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":"44 3","pages":"297-309"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ala Koreitem, A Rain Mocello, Jose Luis Gomez, Gustavo Saggese, Torsten Neilands, Maria Amelia de Sousa Mascena Veras, Sheri A Lippman, Jae Sevelius
{"title":"Intersectional discrimination, mental health, and health care access among transgender women in Brazil.","authors":"Ala Koreitem, A Rain Mocello, Jose Luis Gomez, Gustavo Saggese, Torsten Neilands, Maria Amelia de Sousa Mascena Veras, Sheri A Lippman, Jae Sevelius","doi":"10.1037/hea0001447","DOIUrl":"10.1037/hea0001447","url":null,"abstract":"<p><strong>Objectives: </strong>Intersectional discrimination leads to negative health outcomes among transgender (trans) women. To address the need for validated tools to measure experiences of intersectional discrimination, we evaluated the performance of the Intersectional Discrimination Index (InDI) and measured associations with mental health and health care engagement among trans women in São Paulo, Brazil.</p><p><strong>Method: </strong>Using baseline data from the Manas por Manas randomized controlled trial (n = 392), we characterized participant experiences of intersectional discrimination using the InDI-anticipated (InDI-A), day-to-day (InDI-D), and major (InDI-M) discrimination subscales. We evaluated the validity of the InDI-A using confirmatory factor analysis, and reliability using Cronbach's coefficient alpha (Cα) and explored relationships between each subscale, mental health, and health care engagement.</p><p><strong>Results: </strong>A single-factor solution yielded excellent for InDI-A. All subscales demonstrated good reliability: InDI-A (Cα = .85); InDI-D (lifetime Cα = .84, past-year Cα = .87), InDI-M (lifetime Cα = .78, past-year Cα = .76). A one-unit increase in anticipated discrimination was associated with severe psychological distress, adjusted odds ratio (AOR) = 2.13, 95% confidence interval (CI) [1.57, 2.89], p < .0001, and suicidality (AOR = 1.44, 95% CI [1.08, 1.93], p < .05). Similar patterns emerged for major and day-to-day discrimination. We observed important differences by race. Anticipated discrimination was associated with higher odds of HIV testing (AOR = 1.46, 95% CI [1.08, 1.97], p = .013). Discrimination was not associated with accessing primary care.</p><p><strong>Conclusion: </strong>The InDI is a valid and reliable tool for measuring intersectional discrimination among Brazilian trans women; InDI scores are strongly associated with negative mental health sequelae. Interventions are needed to mitigate structural barriers to care in Brazil, where poor mental health and HIV prevalence are high among trans women. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":"44 3","pages":"256-265"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John A Fuller, James L Fisher, Kaleb Masterson, Tasleem J Padamsee, Scout, Electra D Paskett, Elizabeth K Arthur
{"title":"Social isolation and cancer care delay during COVID-19 in LGBTQI+ cancer survivors.","authors":"John A Fuller, James L Fisher, Kaleb Masterson, Tasleem J Padamsee, Scout, Electra D Paskett, Elizabeth K Arthur","doi":"10.1037/hea0001462","DOIUrl":"10.1037/hea0001462","url":null,"abstract":"<p><strong>Objective: </strong>Lesbian, gay, bisexual, transgender, queer, intersex, and people with other diverse sexual orientations and gender identities (LGBTQI+) experience higher levels of social isolation and delayed cancer screenings, diagnosis, and treatment compared with their non-LGBTQI+ counterparts. The purpose of this study was to examine the association between perceived social isolation (PSI) and delay of cancer screenings, follow-up, or treatment during the coronavirus disease 2019 (COVID-19) pandemic among LGBTQI+ cancer survivors, and to determine if this association varied by race and ethnicity.</p><p><strong>Method: </strong>Data from the National LGBT Cancer Network's OUT: The National Cancer Survey were used. Adult LGBTQI+ cancer survivors (N = 3,023) in the United States were surveyed between September 2020 and March 2021 using self-reported measures of PSI and delay of cancer care since the start of the COVID-19 pandemic. Data analysis included descriptive statistics and logistic regression.</p><p><strong>Results: </strong>LGBTQI+ cancer survivors with high levels of PSI were more likely to delay cancer care than those with low levels of PSI, adjusted OR = 1.29, 95% confidence interval (CI) [1.06, 1.57]. Biracial/multiracial LGBTQI+ cancer survivors were more likely to delay than their White peers (adjusted OR = 3.65, 95% CI [1.58, 8.41]). Aging, intersex variation, loss of employment, and poorer current health status were also associated with significant delay in cancer care.</p><p><strong>Conclusion: </strong>Social isolation and other social determinants of health are important targets for clinical assessment and public health interventions meant to address cancer-related health disparities in LGBTQI+ people, particularly those with intersecting marginalized identities. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":"44 3","pages":"223-233"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brian Mustanski, Kathryn Macapagal, Dennis H Li, Carlos E Rodriguez-Diaz, Rana Saber, Maggie Matson, David A Moskowitz, H Jonathon Rendina, Eric Laber, Daniel T Ryan, Michael E Newcomb
{"title":"Effectiveness of the smart program: Stepped-care HIV prevention for gay and bisexual adolescent boys.","authors":"Brian Mustanski, Kathryn Macapagal, Dennis H Li, Carlos E Rodriguez-Diaz, Rana Saber, Maggie Matson, David A Moskowitz, H Jonathon Rendina, Eric Laber, Daniel T Ryan, Michael E Newcomb","doi":"10.1037/hea0001471","DOIUrl":"10.1037/hea0001471","url":null,"abstract":"<p><strong>Objective: </strong>Adolescent men who have sex with men (AMSM) have high HIV incidence and low rates of HIV testing and pre-exposure prophylaxis (PrEP) use. There are few evidence-based HIV prevention programs that meet the unique needs of AMSM. The sequential, multiple assignment, randomized trial (SMART) program is a stepped care package of increasingly intensive eHealth interventions that were developed specifically for English- and Spanish-speaking AMSM. The sequence included universal sexuality education (SMART Sex Ed), an automated motivation and behavioral skills focused intervention (SMART Squad), and motivational interviewing via videoconferencing (SMART Sessions).</p><p><strong>Method: </strong>This SMART compared HIV testing, PrEP use, condomless anal sex (CAS), condom use intentions, and condom use self-efficacy outcomes for different embedded treatment sequences in the SMART program among a large sample of English- and Spanish-speaking AMSM (ages 13-18) in the U.S. states and territories (N = 1,306).</p><p><strong>Results: </strong>In most of the embedded treatment sequences, there were significant improvements across 12 months for most of the outcomes, including CAS with casual partners, HIV testing, PrEP use, and condom use self-efficacy. There were largely no changes in CAS inclusive of serious partnerships and condom use intentions declined in some regimes.</p><p><strong>Conclusion: </strong>Findings from 12 months of follow-up provide evidence of the SMART program's long-term effectiveness, with particular benefits for the important outcomes of HIV testing and PrEP use. Given the lack of effective interventions for this high HIV-incidence population coupled with the potential for high reach given the eHealth modality, funders should put in place the resources to enable rapid implementation. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":"44 3","pages":"321-331"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberto L Abreu, Aldo M Barrita, Jules P Sostre, Joshua G Parmenter, Ryan J Watson
{"title":"Interest in preexposure prophylaxis, cyberbullying, internalized stigma, and parental acceptance among Latinx sexual and gender diverse youth.","authors":"Roberto L Abreu, Aldo M Barrita, Jules P Sostre, Joshua G Parmenter, Ryan J Watson","doi":"10.1037/hea0001455","DOIUrl":"10.1037/hea0001455","url":null,"abstract":"<p><strong>Objectives: </strong>Internalized social stigma and cyberbullying often lead to negative outcomes and decreased well-being among Latinx sexual and gender diverse (SGD) youth. Fear of being judged by family members deters Latinx SGD youth from using preexposure prophylaxis (PrEP). Parental acceptance can serve as a buffer against negative mental health outcomes for Latinx SGD youth. However, less is known about the role of parental acceptance in experiences of cyberbullying, internalized stigma, and interest in taking PrEP in the future. This study aimed to explore the relationship between cyberbullying (predictor), SGD internalized stigma (mediator), parental acceptance (Moderator 1), and history of sexual intercourse (Moderator 2) on interest in taking PrEP in the future (outcome) using a mediation and moderated mediation analyses.</p><p><strong>Method: </strong>We used a large national, diverse sample of Latinx SGD youth (N = 1,772, ages 13-18) recruited online. We conducted a series of mediation and moderated mediation analyses to test our hypotheses.</p><p><strong>Results: </strong>Our results show that cyberbullying is associated with lower odds of taking PrEP, and internalized SGD stigma helped explain this relation as a mediator. Furthermore, parental acceptance and history of sexual intercourse moderated the relation between cyberbullying and internalized SGD stigma, as well as the relation between cyberbullying and the interest in taking PrEP in the future.</p><p><strong>Conclusion: </strong>Our findings highlight the effects of cyberbullying and internalized stigma on health factors that affect Latinx SGD youth, as well as the role of parental acceptance. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":"44 3","pages":"266-274"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health PsychologyPub Date : 2025-03-01Epub Date: 2025-01-02DOI: 10.1037/hea0001410
Jenna Alley, Jeffrey Gassen, Luis A Parra, Michele D Kipke, Jeremy T Goldbach, Steven W Cole, George M Slavich
{"title":"How community connection, homophobia, and racism shape gene expression in sexual minority men with and without HIV.","authors":"Jenna Alley, Jeffrey Gassen, Luis A Parra, Michele D Kipke, Jeremy T Goldbach, Steven W Cole, George M Slavich","doi":"10.1037/hea0001410","DOIUrl":"10.1037/hea0001410","url":null,"abstract":"<p><strong>Objective: </strong>Although sexual minority men experience substantial discrimination, in addition to increased risk for several serious mental and somatic health problems, the biological mechanisms underlying these effects are unclear. To address this issue, we examined how experiences of social safety (i.e., community connection) and social threat (i.e., discrimination, in the forms of homophobia and racism) were related to conserved transcriptional response to adversity (CTRA) gene expression profiles across time, and whether these associations differed across HIV status, in a well-characterized, racially diverse sample of sexual minority men (<i>M</i><sub>age</sub> = 22.61, <i>SD</i> = 1.90).</p><p><strong>Method: </strong>Experiences of community connection, homophobia, and racism were assessed via self-report, and blood samples were obtained at three timepoints over approximately 2 years. We then used these blood samples to characterize participants' CTRA gene expression, which we quantified using an a priori 53-transcript composite score derived from RNA sequencing data from peripheral blood leukocytes.</p><p><strong>Results: </strong>As hypothesized, greater community connection was significantly related to decreased CTRA gene expression across time. These effects were similar regardless of HIV status and were robust to statistical adjustment for several potential confounding factors. In contrast, neither homophobia nor racism were related to CTRA gene expression.</p><p><strong>Conclusion: </strong>These results suggest that community connection may be a protective factor that reduces biological processes known to negatively impact health. Consequently, interventions and policies aimed at reducing health disparities in marginalized populations may benefit from increasing community connection and inclusion. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":" ","pages":"176-187"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Delaram Ghanooni, Adam W Carrico, Annesa Flentje, Patricia I Moreno, Audrey Harkness, Samantha Dilworth, Savita Pahwa, Suresh Pallikkuth, Seann Regan, Bradley E Aouizerat, Dustin T Duncan
{"title":"Neighborhood-level adversity and inflammation among sexual minority men living with HIV.","authors":"Delaram Ghanooni, Adam W Carrico, Annesa Flentje, Patricia I Moreno, Audrey Harkness, Samantha Dilworth, Savita Pahwa, Suresh Pallikkuth, Seann Regan, Bradley E Aouizerat, Dustin T Duncan","doi":"10.1037/hea0001479","DOIUrl":"10.1037/hea0001479","url":null,"abstract":"<p><strong>Objective: </strong>This cross-sectional study investigated the associations of neighborhood-level factors with immune activation, systemic inflammation, and leukocyte telomere length in 110 sexual minority men with human immunodeficiency virus.</p><p><strong>Method: </strong>From 2013 to 2017, sexual minority men with human immunodeficiency virus who used stimulants were recruited in San Francisco, California and provided blood samples to measure the markers of immune activation, systemic inflammation, and leukocyte telomere length. To measure neighborhood-level indices, the home address for each participant was geocoded and linked to data from the Centers for Disease Control and Prevention. Hierarchical linear modeling was employed to investigate the associations of neighborhood-level factors with systemic inflammation and leukocyte telomere length.</p><p><strong>Results: </strong>After adjusting for age, stimulant use, self-reported income, level of education, and race and ethnicity, residing in neighborhoods with greater percentages of poverty (β = .33, p < .001) and a higher proportion of racial/ethnic minority residents (β = .26, p < .05) were independently associated with higher levels of interleukin-6. Additionally, residing in neighborhoods with higher percentage of uninsured individuals was independently associated with higher tumor necrosis factor-alpha (β = .24, p < .05). Indices of neighborhood-level adversity were additionally associated with providing a urine sample that was reactive for stimulants (OR = 1.31, p = .002), which was, in turn, associated with shorter leukocyte telomere length (β = -.31, p < .05).</p><p><strong>Conclusions: </strong>Future longitudinal research should examine the biobehavioral pathways linking neighborhood-level factors and stimulant use with systemic inflammation and cellular aging. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":"44 3","pages":"188-196"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11856452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leah Davis Ewart, Michaela E Larson, Delaram Ghanooni, Rachel Verhagen, Jennifer Manuel, Kathryn McCollister, Erminia Fardone, Britt DeVries, Samantha Dilworth, Makayla Blackstock, Susanne Doblecki-Lewis, Inbal Nahum-Shani, Christian Grov, Adam W Carrico
{"title":"Getting to yes: Pilot sequential multiple assignment randomized trial of motivational enhancement interventions targeting preexposure prophylaxis use in sexual minority men who use stimulants.","authors":"Leah Davis Ewart, Michaela E Larson, Delaram Ghanooni, Rachel Verhagen, Jennifer Manuel, Kathryn McCollister, Erminia Fardone, Britt DeVries, Samantha Dilworth, Makayla Blackstock, Susanne Doblecki-Lewis, Inbal Nahum-Shani, Christian Grov, Adam W Carrico","doi":"10.1037/hea0001489","DOIUrl":"10.1037/hea0001489","url":null,"abstract":"<p><strong>Objective: </strong>This pilot sequential multiple assignment randomized trial estimated the feasibility, acceptability, and scalability of telehealth motivational enhancement interventions for optimizing HIV prevention efforts in sexual minority men (SMM) who use stimulants.</p><p><strong>Method: </strong>Seventy SMM who use stimulants with nonreactive HIV results that were not taking preexposure prophylaxis (PrEP) were randomized to: (a) a two-session motivational interviewing (MI) intervention focusing on PrEP use and concomitant risk behaviors; or (b) a contingency management (CM) intervention with financial incentives for PrEP clinical evaluation ($50) and filling a PrEP prescription ($50). After 3 months, participants who reported they had not filled a prescription for PrEP were randomized a second time to: (a) switch to a second-stage intervention (i.e., MI + CM); or (b) continue with assessments only.</p><p><strong>Results: </strong>There was a robust engagement in the interventions, which participants described as flexible and nonjudgmental. Participants reported using CM incentives to meet basic needs and indicated that MI sessions improved their understanding of PrEP. The estimated cost of intervention delivery per participant was $404 for MI, $236 for CM, and $475 for MI + CM. Across both randomizations, participants who received CM only were most likely to provide verified evidence of PrEP use over 6 months, and there were potential benefits for reducing concomitant risk behaviors in nonresponders receiving MI + CM. Prior PrEP use and increases in PrEP intentions were significantly associated with verified PrEP use.</p><p><strong>Conclusion: </strong>Although more definitive trials are needed to examine effectiveness, telehealth motivational enhancement interventions are promising, scalable approaches for optimizing HIV prevention among SMM who use stimulants. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":"44 3","pages":"310-320"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Demetria Cain, David Scales, Juan Castiblanco, Jack Gorman, Tyrel J Starks
{"title":"Collective efficacy: A protective factor for sexual minority men during the U.S. mpox outbreak.","authors":"Demetria Cain, David Scales, Juan Castiblanco, Jack Gorman, Tyrel J Starks","doi":"10.1037/hea0001472","DOIUrl":"10.1037/hea0001472","url":null,"abstract":"<p><strong>Objectives: </strong>Collective efficacy is an understudied potential protective factor for health behavior change. This study extends previous research on HIV and COVID-19 infection to test associations with mpox vaccination and symptoms of depression and anxiety among sexual minority men during the mpox outbreak.</p><p><strong>Method: </strong>Between July 28, 2022 and September 22, 2022, adult cisgender sexual minority men (n = 2,614) were recruited from social networking applications and completed a cross-sectional online survey that assessed collective efficacy (united action), mpox vaccination, and symptoms of anxiety and depression.</p><p><strong>Results: </strong>In multivariable regression models, united action was positively associated with having received at least one dose of the mpox vaccine (OR = 1.025, p = .04) and negatively associated with anxiety (β = -.055, p < .004) and depression (β = -.037, p = .05) above and beyond disease-related cognition and behavioral risk factors (sex with casual partners and substance use).</p><p><strong>Conclusion: </strong>These findings suggest that perceptions of community agency to overcome health threats may be associated with individual health benefits. Clinically, these results suggest interventions that activate or develop community-level capacity to cope or respond to disease outbreaks may be useful public health strategies to mitigate infection risk as well as some mental health challenges among members of communities at high risk of infection. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":55066,"journal":{"name":"Health Psychology","volume":"44 3","pages":"211-222"},"PeriodicalIF":3.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12036798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}