Hellenic Journal of Cardiology最新文献

{"title":"Ageism in medicine: procrustean logic in healthcare","authors":"Charalambos Vlachopoulos , Demosthenes Panagiotakos","doi":"10.1016/j.hjc.2025.07.001","DOIUrl":"10.1016/j.hjc.2025.07.001","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 1-3"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the predictive ability of GRACE 2.0 and GRACE 3.0 scores in a Greek cohort of patients hospitalized with acute coronary syndrome","authors":"Christos Kofos , Andreas S. Papazoglou , Stavroula Rousopoulou , Paraskevi Douki , Andreas Takas , Athanasios Samaras , Panagiotis Stachteas , Athina Nasoufidou , Efstratios Karagiannidis , Barbara Fyntanidou , Nikolaos Fragakis , George Kassimis","doi":"10.1016/j.hjc.2024.10.002","DOIUrl":"10.1016/j.hjc.2024.10.002","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 108-109"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial fibrillation post CABG and the risk of arrhythmia recurrence: the AFRODITE study","authors":"Maria Nikolaou ,&nbsp;Gregory Pattakos ,&nbsp;Christos Hitas ,&nbsp;Katerina Koniari ,&nbsp;Antoniοs Pitsis ,&nbsp;Dimitrios Iliopoulos ,&nbsp;Αnastasia Xintarakou ,&nbsp;Emmanouil P. Vardas ,&nbsp;Stratis Pattakos ,&nbsp;Stylianos Tzeis ,&nbsp;Panagiotis Vardas","doi":"10.1016/j.hjc.2024.03.003","DOIUrl":"10.1016/j.hjc.2024.03.003","url":null,"abstract":"<div><h3>Background</h3><div>New-onset postoperative atrial fibrillation (POAF) after coronary artery bypass surgery (CABG) occurs with an incidence of 20–40%. The clinical relevance of POAF remains a concern, and the need for further studies regarding the clinical management of POAF is necessary.</div></div><div><h3>Aim</h3><div>The AFRODITE study, a prospective multicenter cohort study, had as its primary endpoint the evaluation of AF recurrence in patients post CABG over a one-year period.</div></div><div><h3>Methods</h3><div>Two hundred twenty-eight patients aged &gt;50 years who underwent isolated CABG were included in the study. Patients were stratified into two groups, POAF and non-POAF, and followed for 12 months for AF recurrence, hospitalizations, and death.</div></div><div><h3>Results</h3><div>Two hundred twenty-eight patients (mean age 67 years, 88.6% male) were included in the study. 28.5% of patients experienced at least one episode of POAF during index hospitalization (POAF group) and were compared with the non-POAF group (n = 163). Multivariate stepwise logistic regression analysis showed that the strongest prognostic parameter for POAF was the CHA₂DS_2-VASc score (odds ratio = 1.61, p &lt; 0.001). POAF patients had a worse in-hospital outcome, but the incidence of long-term AF recurrence was not statistically different (3.6% vs. 4.8%, p = 0.9).</div></div><div><h3>Conclusion</h3><div>Interestingly, a one-year prospective follow-up of patients in the study did not reveal significant differences between POAF and non-POAF patients. A notable finding was that patients with a higher CHA₂DS_2-VASc score were more likely to develop POAF.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 13-21"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of mitral valve regurgitation in patients with heart failure with mildly reduced ejection fraction","authors":"Noah Abel ,&nbsp;Michael Behnes ,&nbsp;Alexander Schmitt ,&nbsp;Marielen Reinhardt ,&nbsp;Felix Lau ,&nbsp;Mohammad Abumayyaleh ,&nbsp;Tina Sieburg ,&nbsp;Kathrin Weidner ,&nbsp;Mohamed Ayoub ,&nbsp;Kambis Mashayekhi ,&nbsp;Ibrahim Akin ,&nbsp;Tobias Schupp","doi":"10.1016/j.hjc.2024.03.013","DOIUrl":"10.1016/j.hjc.2024.03.013","url":null,"abstract":"<div><h3>Background</h3><div>Although mitral valve regurgitation (MR) is a common valvular heart disease in patients with heart failure (HF), there is a paucity of data on the characterization and outcomes of patients with HF with mildly reduced ejection fraction (HFmrEF) and concomitant MR.</div></div><div><h3>Methods</h3><div>From 2016 to 2022, consecutive patients hospitalized with HFmrEF (i.e., left ventricular ejection fraction from 41% to 49% and signs and/or symptoms of HF) were retrospectively included at one institution. Patients with MR were compared with patients without MR. Further risk stratification was performed according to MR severity and etiology (i.e., primary vs. secondary MR). The primary end point was all-cause mortality at 30 months (median follow-up), and the key secondary end point was hospitalization for worsening HF.</div></div><div><h3>Results</h3><div>Of 2181 patients hospitalized with HFmrEF, 59% presented with mild, 10% with moderate, and 2% with severe MR. MR was associated with increased all-cause mortality at 30 months (HR = 1.756; 95% CI 1.458–2.114; p = 0.001), with higher risk in more advanced stages. Furthermore, MR patients had higher risk of HF-related re-hospitalization at 30 months (HR = 1.560; 95% CI 1.172–2.076; p = 0.002). Even after multivariable adjustment, mild, moderate, and severe MR were still associated with all-cause mortality. Finally, the risk of all-cause mortality was lower in patients with secondary MR compared with patients with primary MR (HR = 0.592; 95% CI 0.366–0.956; p = 0.032).</div></div><div><h3>Conclusion</h3><div>MR is common in HFmrEF and independently associated with higher risk of all-cause mortality and HF hospitalization.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 61-74"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140332332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of polymer-free biolimus-eluting stents versus durable polymer novolimus-eluting stents in a real-world clinical practice (FREEDOM-DES trial)","authors":"Soohyung Park ,&nbsp;Seung-Woon Rha ,&nbsp;Byoung Geol Choi ,&nbsp;Sang Ho Park ,&nbsp;Jae-Bin Seo ,&nbsp;Ju Yeol Baek ,&nbsp;Jae Woong Choi ,&nbsp;Yong Hoon Kim ,&nbsp;Ji-Hun Ahn ,&nbsp;Gi Chang Kim ,&nbsp;Weon Kim ,&nbsp;Soo-Han Kim ,&nbsp;Markz RMP. Sinurat ,&nbsp;Se Yeon Choi ,&nbsp;Jin Ah Cha ,&nbsp;Su Jin Hyun ,&nbsp;Cheol Ung Choi ,&nbsp;Chang Gyu Park","doi":"10.1016/j.hjc.2024.09.005","DOIUrl":"10.1016/j.hjc.2024.09.005","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 104-107"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massive right coronary aneurysm-left ventricle fistula","authors":"Xiangfeng Gong ,&nbsp;Chunyan Jiang ,&nbsp;Chaoyi Qin ,&nbsp;Xiaoqin Chen ,&nbsp;Zhenghua Xiao","doi":"10.1016/j.hjc.2025.03.006","DOIUrl":"10.1016/j.hjc.2025.03.006","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 114-115"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sacubitril/valsartan reversal of left ventricular remodeling is associated with improved hemodynamics in resistant hypertension","authors":"Lixue Song ,&nbsp;Hongrui Yang ,&nbsp;Xiang Ning ,&nbsp;Yanyan Ma ,&nbsp;Aiying Xue ,&nbsp;Yimeng Du ,&nbsp;Qinghua Lu ,&nbsp;Zhendong Liu ,&nbsp;Xin Wang ,&nbsp;Juan Wang","doi":"10.1016/j.hjc.2024.03.012","DOIUrl":"10.1016/j.hjc.2024.03.012","url":null,"abstract":"<div><h3>Background</h3><div>Sacubitril/valsartan (S/V) has been shown to be an effective antihypertensive drug combination. However, its therapeutic effects on blood pressure (BP), hemodynamics, and left ventricular (LV) remodeling in resistant hypertension (RHTN) remain unclear.</div></div><div><h3>Methods</h3><div>Eighty-six patients completed this self-control study, during which olmesartan was administered within the first 8 weeks (phase 1), followed by S/V within the second 8 weeks (phase 2), with nifedipine and hydrochlorothiazide taken as background medications. Office BP, echocardiography, and hemodynamics assessment using impedance cardiography were performed at baseline and at the eighth and sixteenth weeks.</div></div><div><h3>Results</h3><div>The reduction in office BP was larger in phase 2 than in phase 1 (19.59/11.66 mmHg vs. 2.88/1.15 mmHg). Furthermore, the treatment in phase 2 provided greater reductions in systemic vascular resistance index (SVRI) and thoracic blood saturation ratio (TBR), with differences between the two phases of −226.59 (−1212.80 to 509.55) dyn·s/cm⁵/m² and −0.02 (−0.04 to 0.02). Switching from olmesartan to S/V also significantly reduced E/E′, LV mass index, LV end-diastolic volume index, and LV end-systolic volume index (all <em>P</em> &lt; 0.05). Decreases in arterial stiffness, SVRI, and TBR were correlated with changes in indicators of LV remodeling (all <em>P</em> &lt; 0.05). This correlation persisted even after adjusting for confounders including changes in BP.</div></div><div><h3>Conclusions</h3><div>Switching from olmesartan to S/V effectively lowered BP and reversed ventricular remodeling in RHTN. In addition, hemodynamic improvement was also observed. Changes in hemodynamics played an important role in reversing LV remodeling of S/V, and were independent of its antihypertensive effect.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 51-60"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140583947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of radial artery occlusion after transradial coronary catheterization: a review of the literature and proposed treatment algorithm","authors":"Matthaios Didagelos ,&nbsp;Dimitrios Afendoulis ,&nbsp;Areti Pagiantza ,&nbsp;Dimitrios Moysidis ,&nbsp;Andreas Papazoglou ,&nbsp;Charalambos Kakderis ,&nbsp;Stylianos Daios ,&nbsp;Vasileios Anastasiou ,&nbsp;Konstantinos C. Theodoropoulos ,&nbsp;Antonios Kouparanis ,&nbsp;Athanasios Kartalis ,&nbsp;Vasileios Kamperidis ,&nbsp;George Kassimis ,&nbsp;Antonios Ziakas","doi":"10.1016/j.hjc.2025.01.008","DOIUrl":"10.1016/j.hjc.2025.01.008","url":null,"abstract":"<div><div>The transradial artery has been established as the default access site for most coronary catheterization procedures with fewer access-related and bleeding complications, rapid hemostasis, early ambulation of the patient, and reduction in all-cause mortality compared with transfemoral access. However, radial artery occlusion (RAO) remains the most frequent complication of coronary catheterization procedures performed via transradial artery access. The purpose of our review was to conduct detailed literature research and summarize all the available treatment strategies for RAO, given the lack of a standardized treatment protocol in the literature. Pharmacological treatment with low-molecular-weight heparin (LMWH) or other anticoagulants, invasive strategies, and pharmaco-invasive methods available in the literature were included in our review. Data were derived from case series, case reports, clinical trials, and observational studies. Eight studies regarding pharmacological treatment with LMWH or any other anticoagulant and seven studies of invasive treatment were included in our review. There were only two randomized studies: one with LMWH (tinzaparin) and one with apixaban. Furthermore, taking into consideration data derived from the above-mentioned studies, a treatment algorithm for RAO was proposed. RAO remains the most frequent complication of coronary procedures with transradial access. Application of preventive strategies and comprehensive knowledge of the risk factors remain the key factors for the reduction of the incidence of this clinical entity. Therapeutic options include anticoagulation regimens and interventional techniques through the distal radial artery. Large, randomized, multicenter studies should be conducted to evaluate the efficacy of the available treatment methods and define a standardized treatment protocol for RAO.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 81-95"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left bundle branch area pacing versus conventional pacing in patients with advanced atrioventricular conduction abnormalities: a prospective cohort study","authors":"Georgios Leventopoulos ,&nbsp;Panagiotis Patrinos ,&nbsp;Angeliki Papageorgiou ,&nbsp;Spyridon Katechis ,&nbsp;Angelos Perperis ,&nbsp;Christoforos Travlos ,&nbsp;Panagiota Spyropoulou ,&nbsp;Nikolaos Koutsogiannis ,&nbsp;Athanasios Moulias ,&nbsp;Periklis Davlouros","doi":"10.1016/j.hjc.2024.03.005","DOIUrl":"10.1016/j.hjc.2024.03.005","url":null,"abstract":"<div><h3>Background</h3><div>Left bundle branch area pacing (LBBAP) is an emerging pacing method that may prevent the deleterious effects of right ventricular pacing. The aim of this study is to compare the effects of LBBAP with right ventricular septal pacing (RVSP) in patients with advanced atrioventricular conduction abnormalities and preserved left ventricular ejection fraction.</div></div><div><h3>Methods</h3><div>The effect of pacing was evaluated by echocardiographic indices of dyssynchrony, including global myocardial work efficiency (GWE) and peak systolic dispersion (PSD). The primary endpoint was GWE postprocedural, at 3, 6, and 12 months after the procedure.</div></div><div><h3>Results</h3><div>Twenty patients received LBBAP and 18 RVSP. Complete follow-up was accomplished in 37 patients (97.4%) due to the death of a patient (RVSP arm) from nonrelated cause. GWE was significantly increased in the group of LBBAP compared to RVSP at all time points (90.8% in LBBAP versus 85.8% in RVSP group at 12 months, p = 0.01). PSD was numerically lower in the LBBAP arm at all time points, yet not statistically significant (56.4 msec in LBBP versus 65.1 msec in RVSP arm at 12 months, p = 0.178). The implantation time was increased (median 93 min in LBBAP versus 45 min in RVSP group, p &lt; 0.01), along with fluoroscopy time and dose area product (DAP), in the arm of LBBAP. There were no severe perioperative acute complications in either group.</div></div><div><h3>Conclusions</h3><div>LBBAP is an emerging and safe technique for patients with a pacing indication. Despite the longer procedural and fluoroscopy time, as well as higher DAP, LBBAP seems to offer better left ventricular synchrony compared to RVSP, according to GWE measurements.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 32-42"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trileaflet mitral valve as an unusual cause of double-chambered left ventricle","authors":"Yudong Peng ,&nbsp;Man Zhang","doi":"10.1016/j.hjc.2025.03.007","DOIUrl":"10.1016/j.hjc.2025.03.007","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"84 ","pages":"Pages 116-117"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}