Hellenic Journal of Cardiology最新文献

{"title":"Generative artificial intelligence tools in scientific writing: entering a brave new world?","authors":"Charalambos Vlachopoulos (Editor-in-Chief, Hellenic Journal of Cardiology), Alexios Antonopoulos (Executive Editor, Hellenic Journal of Cardiology), Dimitrios Terentes-Printzios (Executive Editor, Hellenic Journal of Cardiology)","doi":"10.1016/j.hjc.2024.05.014","DOIUrl":"10.1016/j.hjc.2024.05.014","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1109966624001180/pdfft?md5=f491423c0238a1c17cd8ae65ed84c2cb&pid=1-s2.0-S1109966624001180-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141143794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Chios Mastiha essential oil on cholesterol levels of healthy volunteers: A prospective, randomized, placebo-controlled study (MASTIHA-OIL)","authors":"Athanasios Kartalis ,&nbsp;Dimitrios Afendoulis ,&nbsp;Matthaios Didagelos ,&nbsp;Michail Ampeliotis ,&nbsp;Maria Moutafi ,&nbsp;Petros Voutas ,&nbsp;Nikolaos Smyrnioudis ,&nbsp;Nikolaos Papagiannis ,&nbsp;Stefanos Garoufalis ,&nbsp;Eirini Boula ,&nbsp;Ilias Smyrnioudis ,&nbsp;Charalambos Vlachopoulos","doi":"10.1016/j.hjc.2023.08.011","DOIUrl":"10.1016/j.hjc.2023.08.011","url":null,"abstract":"<div><h3>Introduction</h3><p>Chios Mastiha essential oil (CMO) is a natural product extracted from the resin of Mastiha, possessing antioxidant, anti-microbial, anti-ulcer, anti-neoplastic, and cholesterol-lowering capabilities in vitro, and its hypolipidemic effect was confirmed in animal studies. Yet, there are no randomized, placebo-controlled clinical studies in the literature regarding CMO's hypolipidemic effects in humans. A prospective, randomized, placebo-controlled study was designed to study the hypolipidemic effect of CMO capsules on healthy volunteers with elevated cholesterol.</p></div><div><h3>Methods</h3><p>192 healthy volunteers were screened and 160 of them with total cholesterol&gt; 200 mg/dl participated in the study. They were randomized with a 2:1 ratio of receiving CMO capsules (200 mg mastiha-oil/capsule) and placebo for 8 weeks respectively. 113 patients received CMO and 47 were randomized in the control group, and all of them completed the follow-up period.</p></div><div><h3>Results</h3><p>After 8 weeks of CMO administration, total and LDL cholesterol were significantly lower in the CMO compared to the placebo group 215.2 ± 27.5 vs 237.0 ± 27.9 mg/dl (p &lt; 0.001) and 135.0 ± 26.1 vs 153.0 ± 23.3 mg/dl (p &lt; 0.001) respectively. No gastrointestinal adverse events or liver or renal toxicity were reported. Additionally, in the CMO group total cholesterol was significantly decreased by 20.6 mg/dl (9%), LDL by 18.1 mg/dl (12%), triglycerides by 21.8 mg/dl (15%), and glucose by 4.6 mg/dl (5%) and HDL was increased by 2.4 mg/dl (5%), compared to their baseline values.</p></div><div><h3>Conclusion</h3><p>The MASTIHA-OIL study showed the efficacy and safety of CMO in reduction of total and LDL cholesterol after 8 weeks of administration in healthy volunteers with elevated cholesterol levels.</p></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1109966623001483/pdfft?md5=97cc4919028d640370037265f5d2820d&pid=1-s2.0-S1109966623001483-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10187143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic benefits of early vascular surgical intervention in patients with major peripheral vascular complications following transcatheter aortic valve implantation","authors":"Sebastian Barth ,&nbsp;Mohammed Ahmed ,&nbsp;Martina B. Hautmann ,&nbsp;Wilko Reents ,&nbsp;Michael Zacher ,&nbsp;Sebastian Kerber ,&nbsp;Ulrich Lüsebrink ,&nbsp;Thomas C. Schmandra","doi":"10.1016/j.hjc.2023.08.007","DOIUrl":"10.1016/j.hjc.2023.08.007","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to analyze the incidence, surgical management of major vascular complications, and outcomes in patients undergoing transfemoral (TF) transcatheter aortic valve replacement (TAVR) at our center after strict selection of the access route, carefully considering all known major predictors.</p></div><div><h3>Methods</h3><p>Data of 494 consecutive patients with pre-interventional multi-slice computed tomography (CT) of the aorta who had undergone TF TAVR from 2009 to 2019 were analyzed.</p></div><div><h3>Results</h3><p>In total, 23/494 (4.7%) patients had major vascular and access-related complications of peripheral vessels and/or infrarenal aorta. These included hematomas that met the Valve Academic Research Consortium 3-criteria of major vascular complications (7/494, 1.4%), arterial dissections (3/494, 0.6%), pseudoaneurysm (6/494, 1.2%), thrombus of the external iliac artery leading to acute limb ischemia (1/494, 0.2%), fistula (1/494, 0.2%), and perforation (5/494, 1.0%). In total, 17/23 (73.9%) major vascular complications required immediate endovascular and/or open surgery. In 16/17 (94%) cases, only 1 surgical procedure was performed.</p><p>The long-term survival of patients with and without major vascular complications of the peripheral vessels was determined after 2 years.</p></div><div><h3>Conclusions</h3><p>Early vascular surgery intervention reversed the mortality disadvantage in patients with major complications of the peripheral vessels after TAVR. This underscores the importance of immediate vascular surgery stand-by as an indispensable requirement.</p></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1109966623001446/pdfft?md5=df9e2a926fe6f9fff6dd198b017b9c4b&pid=1-s2.0-S1109966623001446-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10490407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimated pulse wave velocity predicts mortality in patients with heart failure with preserved ejection fraction","authors":"Ruicong Xue, Jiancheng Zhang, Zhe Zhen, Weihao Liang, Yi Li, Lili Zhang, Yugang Dong, Bin Dong, Chen Liu","doi":"10.1016/j.hjc.2024.05.013","DOIUrl":"https://doi.org/10.1016/j.hjc.2024.05.013","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141143238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical aortic valvuloplasty is a better primary intervention for isolated congenital aortic stenosis in children with bicuspid aortic valve than balloon aortic valvuloplasty","authors":"Qiushi Ren ,&nbsp;Juemin Yu ,&nbsp;Tianyu Chen ,&nbsp;Hailong Qiu ,&nbsp;Tao Liu ,&nbsp;Jianzheng Cen ,&nbsp;Shusheng Wen ,&nbsp;Jian Zhuang ,&nbsp;Xiaobing Liu","doi":"10.1016/j.hjc.2023.05.012","DOIUrl":"10.1016/j.hjc.2023.05.012","url":null,"abstract":"<div><h3>Objectives</h3><p>Surgical aortic valvuloplasty (SAV) and balloon aortic valvuloplasty (BAV) are two main treatments for children with isolated congenital aortic stenosis (CAS). We aim to compare the two procedures' midterm outcomes, including valve function, survival, reintervention, and replacement.</p></div><div><h3>Methods</h3><p>From January 2004 to January 2021, children with isolated CAS undergoing SAV (n = 40) and BAD (n = 49) at our institution were included in this study. Patients were also categorized into subgroups based on the aortic leaflet number(Tricuspid = 53, Bicuspid = 36) to compare the two procedures’ outcomes. Clinical and echocardiogram data were analyzed to identify risk factors for suboptimal outcomes and reintervention.</p></div><div><h3>Results</h3><p>Postoperative peak aortic gradient (PAG) and PAG at follow-up in the SAV group were lower compared with the BAV group (p &lt; 0.001, p = 0.001, respectively). There was no difference in moderate or severe AR in the SAV group compared with the BAV group before discharge (5.0% vs 12.2%, p = 0.287) and at the last follow-up (30.0% vs 32.7%, p = 0.822). There were no early death but three late deaths (SAV = 2, BAV = 1). Kaplan-Meier estimated survivals were 86.3% and 97.8% in SAV and BAV groups respectively at 10 years (p = 0.54). There was no significant difference in freedom from reintervention (p = 0.22). For patients with bicuspid aortic valve morphology, SAV achieved higher freedom from reintervention (p = 0.011) and replacement (p = 0.019). Multivariate analysis indicated that residual PAG was a risk factor for reintervention (p = 0.045).</p></div><div><h3>Conclusions</h3><p>SAV and BAV achieved excellent survival and freedom from reintervention in patients with isolated CAS. SAV performed better in PAG reduction and maintenance. For patients with bicuspid AoV morphology, SAV was the preferred choice.</p></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1109966623001057/pdfft?md5=72b54a13fea41be337860b769a72e008&pid=1-s2.0-S1109966623001057-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9924211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of patient-oriented mHealth interventions in improving heart failure outcomes: A systematic review of the literature","authors":"Dimitrios Mouselimis ,&nbsp;Anastasios Tsarouchas ,&nbsp;Vassilios P. Vassilikos ,&nbsp;Angelos C. Mitsas ,&nbsp;Charalampos Lazaridis ,&nbsp;Emmanuel Androulakis ,&nbsp;Alexandros Briasoulis ,&nbsp;Polydoros Kampaktsis ,&nbsp;Christodoulos E. Papadopoulos ,&nbsp;Constantinos Bakogiannis","doi":"10.1016/j.hjc.2023.11.001","DOIUrl":"10.1016/j.hjc.2023.11.001","url":null,"abstract":"<div><p>Heart failure (HF) is a debilitating disease with 26 million patients worldwide. Consistent and complex self-care is required on the part of patients to adequately adhere to medication and to the lifestyle changes that the disease necessitates. Mobile health (mHealth) is being increasingly incorporated in patient interventions in HF, as smartphones prove to be ideal platforms for patient education and self-help assistance. This systematic review aims to summarize and report on all studies that have tested the effect of mHealth on HF patient outcomes. Our search yielded 17 studies, namely 11 randomized controlled trials and six non-randomized prospective studies. In these, patients with the assistance of an mHealth intervention regularly measured their blood pressure and/or body weight and assessed their symptoms. The outcomes were mostly related to hospitalizations, clinical biomarkers, patients’ knowledge about HF, quality of life (QoL) and quality of self-care. QoL consistently increased in patients who received mHealth interventions, while study results on all other outcomes were not as ubiquitously positive. The first mHealth interventions in HF were not universally successful in improving patient outcomes but provided valuable insights for patient-oriented application development. Future trials are expected to build on these insights and deploy applications that measurably assist HF patients.</p></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1109966623001999/pdfft?md5=28951b60e49a06d3a3ea8e44fcc0e042&pid=1-s2.0-S1109966623001999-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodality imaging in patients with implantable loop recorders: Tips and tricks","authors":"Dinea Bučić ,&nbsp;Maja Hrabak-Paar","doi":"10.1016/j.hjc.2023.12.001","DOIUrl":"10.1016/j.hjc.2023.12.001","url":null,"abstract":"<div><p>An implantable loop recorder (ILR) is a leadless rectangular device used for prolonged electrocardiographic monitoring for up to 3 years. This miniaturized device, inserted subcutaneously, allows clinicians to investigate possible cardiac rhythm disturbances in patients suffering from recurrent unexplained syncope. As the age of the population increases rapidly and the number of ILR patients amplifies, the clinical significance of ILRs is undeniable. Although radioopaque and easily seen on plain chest radiographs and other imaging modalities, ILRs may represent a challenge for clinicians and radiologists to recognize their classic appearance and differentiate them from numerous other cardiac devices. This article aims to summarize current literature on ILRs, their basic function, types, and indications for implantation, but most of all, it aims to familiarize clinicians and radiologists with common imaging features of these devices, safety issues, and artifact-reducing methods. Specifically, this review discusses the typical appearance of ILRs on major diagnostic imaging modalities, including chest X-ray, mammography, ultrasonography, computed tomography, and magnetic resonance imaging (MRI). Furthermore, optimization strategies to mitigate image artifacts and safety issues regarding MRI are discussed.</p></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1109966623002270/pdfft?md5=8b7b8a14ea3dbea62791bacc8549af6b&pid=1-s2.0-S1109966623002270-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138629559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure and function of the novel interdisciplinary outpatient clinic “65+” for the elderly in Greece: The role of the cardiologist","authors":"Maria Nikolaou,&nbsp;Katerina Spyridaki,&nbsp;Sofia Kalantzi,&nbsp;Vassilis Milionis,&nbsp;Michalitsa Christodoulou,&nbsp;Ioanna Nella,&nbsp;Gesthimani Triantafylli,&nbsp;Sofia Athinaiou,&nbsp;Aggeliki Spathara,&nbsp;Anastasios Marathonitis,&nbsp;Georgios Marathonitis","doi":"10.1016/j.hjc.2023.09.005","DOIUrl":"10.1016/j.hjc.2023.09.005","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1109966623001562/pdfft?md5=e996a770c95d5e6fd408652a844cdb07&pid=1-s2.0-S1109966623001562-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10202575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pheochromocytoma-induced takotsubo cardiomyopathy: Beware of the rapid recovery","authors":"Andreas Mitsis,&nbsp;Michaela Kyriakou,&nbsp;Panayiotis Avraamides","doi":"10.1016/j.hjc.2024.01.003","DOIUrl":"10.1016/j.hjc.2024.01.003","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1109966624000034/pdfft?md5=4fc98a7eb668574609bd560f8323d053&pid=1-s2.0-S1109966624000034-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right ventricular–pulmonary arterial coupling in patients with implanted left ventricular assist devices","authors":"Maciej Stąpór ,&nbsp;Dorota Sobczyk ,&nbsp;Grzegorz Wasilewski ,&nbsp;Karol Wierzbicki ,&nbsp;Andrzej Gackowski ,&nbsp;Paweł Kleczyński ,&nbsp;Krzysztof Żmudka ,&nbsp;Bogusław Kapelak ,&nbsp;Jacek Legutko","doi":"10.1016/j.hjc.2023.06.002","DOIUrl":"10.1016/j.hjc.2023.06.002","url":null,"abstract":"<div><h3>Objective</h3><p>Both the right ventricular (RV) contractile function and pulmonary arterial (PA) pressure influence clinical outcomes in patients supported with left ventricular assist devices (LVADs), but the impact of RV-PA coupling is unknown. This study aimed to determine the prognostic impact of RV-PA coupling in patients with implanted LVADs.</p></div><div><h3>Methods</h3><p>Patients with implanted third-generation LVADs were retrospectively enrolled. The RV-PA coupling was assessed preoperatively by the ratio of RV free wall strain (RVFWS) derived from speckle-tracking echocardiography and noninvasively measured peak RV systolic pressure (RVSP). The primary end point was a composite of all-cause mortality or right heart failure (RHF) hospitalization. Secondary end points consisted of all-cause mortality at a 12-month follow-up and RHF hospitalization.</p></div><div><h3>Results</h3><p>A total of 103 patients were screened, and 72 with good RV myocardial imaging were included. The median age was 57 years; 67 patients (93.1%) were men, and 41 (56,9%) had dilated cardiomyopathy. A receiver-operating characteristic analysis (AUC 0.703, 51.5% sensitivity, 94.9% specificity) was used to identify the optimal cutoff point (0.28%/mmHg) for the RVFWS/TAPSE threshold. Nineteen subjects (26.4%) had advanced RV-PA uncoupling. Event rates were estimated using the Kaplan-Meier method showing a strong association with an increased risk for the primary end point of death or RHF hospitalization (89.47% vs. 30.19%, p &lt; 0.001). A similar observation applied to all-cause mortality (47.37% vs. 13.21%, p = 0.003) and RHF hospitalization (80.43% vs. 20%, p &lt; 0.001).</p></div><div><h3>Conclusions</h3><p>An advanced RV dysfunction assessed by RV-PA coupling may serve as a predictor of adverse outcomes in patients with implanted LVADs.</p></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":null,"pages":null},"PeriodicalIF":4.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1109966623001070/pdfft?md5=2d3fc1eca500f9140cbe70c35fb945fb&pid=1-s2.0-S1109966623001070-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9655329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}