Hellenic Journal of Cardiology最新文献

{"title":"Comparison of continuous flow centrifugal left ventricular assist devices as a bridge to transplant strategy in a low organ donation environment: single center experience","authors":"Michael Bonios ,&nbsp;Dimitris Miliopoulos,&nbsp;Angeliki Gkouziouta,&nbsp;Nektarios Kogerakis,&nbsp;Sokratis Fragkoulis,&nbsp;Iakovos Armenis,&nbsp;Dimitrios Zarkalis,&nbsp;Konstantinos Ieromonachos,&nbsp;Antigoni Koliopoulou,&nbsp;Evangelos Leontiadis,&nbsp;Panagiota Georgiadou,&nbsp;Vasiliki Vartela,&nbsp;Dimitrios Tsiapras,&nbsp;Petros Sfirakis,&nbsp;Christos Kapelios,&nbsp;Stavros Dimopoulos,&nbsp;Loukas Kaklamanis,&nbsp;Dimitrios Ntegiannis,&nbsp;Theofani Antoniou,&nbsp;Themistokles Chamogeorgakis,&nbsp;Stamatis Adamopoulos","doi":"10.1016/j.hjc.2024.10.004","DOIUrl":"10.1016/j.hjc.2024.10.004","url":null,"abstract":"<div><h3>Objective</h3><div>In patients with advanced heart failure, heart transplantation is currently the most effective treatment. However, in a low-organ donation environment, it is usually necessary to proceed in long-term mechanical circulatory support through left ventricular assist device (LVAD) implantation as bridge-to-transplantation.</div></div><div><h3>Methods</h3><div>The study included all patients with advanced heart failure who underwent continuous flow LVAD implantation as a bridge to transplant strategy in our center (n = 68). Following LVAD implantation and for the period that patients were on LVAD support, pump thrombosis, strokes, gastrointestinal bleeding, and right heart failure occurrence rates were recorded. Outcomes were compared between patients implanted with HeartMate 3 (HM3) and HeartWare LVADs, as well as between patients who did reach heart transplantation (HTx group) and those who did not (noHTx group).</div></div><div><h3>Results</h3><div>A total of 35 out of 68 patients underwent heart transplantation at a mean time of 691 ± 457 days; 41 received a HeartWare and 27 a HM3 device. HM3 patients had significantly better survival (p = 0.010) and lower complication rates (p = 0.025). In addition, the noHTx group had significantly higher complication rates compared with the HTx group (p = 0.00041). The 5-year estimated Kaplan–Meier survival rate following heart transplantation was 77%.</div></div><div><h3>Conclusion</h3><div>Patients with advanced heart failure gain substantial benefit from LVADs awaiting heart transplantation. In a low organ donation environment, the need for reliable LVADs can further improve the outcomes through the reduction of complications provided by current devices.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 63-72"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TAV-in-TAV and left main protection: from comprehensive evaluation to precision deployment","authors":"Panagiotis Varelas ,&nbsp;Dimitrios Tsikaderis ,&nbsp;Nikolaos Mezilis ,&nbsp;Konstantinos Manousopoulos ,&nbsp;Konstantinos Filippou ,&nbsp;Ioannis Tsiafoutis ,&nbsp;Petros Dardas","doi":"10.1016/j.hjc.2025.06.006","DOIUrl":"10.1016/j.hjc.2025.06.006","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 114-115"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144370063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ECMO versus IABP for patients with STEMI complicated by cardiogenic shock undergoing primary PCI: a Chinese National Study and propensity-matched analysis","authors":"Hongbo Yang ,&nbsp;Lingfeng Luo ,&nbsp;Yanan Song ,&nbsp;Jiatian Cao ,&nbsp;Jing Chen ,&nbsp;Feng Zhang ,&nbsp;Yiwen Tan ,&nbsp;Yan Zheng ,&nbsp;Zhonghan Sun ,&nbsp;Juying Qian ,&nbsp;Zheyong Huang ,&nbsp;Junbo Ge","doi":"10.1016/j.hjc.2024.09.008","DOIUrl":"10.1016/j.hjc.2024.09.008","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigated the association between the utilization of extracorporeal membrane oxygenation (ECMO) or intra-aortic balloon pump (IABP) and in-hospital mortality among patients with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock undergoing primary percutaneous coronary intervention (PCI).</div></div><div><h3>Methods</h3><div>Data encompassing 9635 cases of STEMI complicated by cardiogenic shock and treated with primary PCI using ECMO/IABP support were retrieved from the Chinese Cardiovascular Association database (2019–2021). We conducted an analysis to assess the in-hospital survival disparities among percutaneous mechanical circulatory device recipients and explore the potential advantages of ECMO through multivariable logistic regression analysis within a propensity score–matched (1:2) cohort population.</div></div><div><h3>Results</h3><div>ECMO was administered to 2028 patients, whereas IABP was used in 7607 patients. Patients supported by ECMO showed a lower in-hospital mortality than those supported by IABP (7.2% versus 15.1%, p &lt; 0.001). Within the propensity-matched (case: control = 1:2) cohort, we noted a 34% reduced risk of in-hospital mortality among patients supported by ECMO compared with those supported by IABP (7.7% versus 11.7%; odds ratio = 0.66; 95% CI, 0.53–0.80; p &lt; 0.001) independent of age, sex, systolic blood pressure, obesity, smoke, hypertension, diabetes, dyslipidemia, family history of coronary artery disease, coronary artery disease, stroke, atrial filiation, peripheral artery disease, chronic kidney disease, vascular lesion sites, 3A-grade hospital, and regional distributions in China.</div></div><div><h3>Conclusion</h3><div>Among patients undergoing primary PCI for STEMI complicated by cardiogenic shock, ECMO was associated with better in-hospital survival than IABP.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 4-12"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term myocardial performance of the systemic right ventricle during exercise in patients with transposition of the great arteries and atrial switch operation","authors":"Urszula Alicja Kozicka ,&nbsp;Katarzyna Kożuch ,&nbsp;Krzysztof Sadowski ,&nbsp;Tripti Gupta ,&nbsp;Piotr Hoffman ,&nbsp;Piotr Szymański ,&nbsp;Mirosław Kowalski ,&nbsp;Magdalena Lipczyńska","doi":"10.1016/j.hjc.2024.08.004","DOIUrl":"10.1016/j.hjc.2024.08.004","url":null,"abstract":"<div><h3>Objective</h3><div>The echocardiographic assessment of the systemic right ventricle (sRV) performance during stress testing is limited and evaluation is not routinely performed. The aim of the study is to investigate sRV myocardial performance at rest and with exercise in patients with complete transposition of the great arteries (dTGA) who have undergone atrial switch operation.</div></div><div><h3>Methods</h3><div>In a single-center cross-sectional study, 41 patients with dTGA following the atrial switch operation and gender-matched 20 healthy volunteers underwent exercise echocardiography on a bicycle ergometer in the semi-supine position to assess sRV systolic function indices: tricuspid annular plane systolic excursion (TAPSE), right ventricular area change (FAC), global longitudinal strain (GLS) and systemic velocity time integral (VTI).</div></div><div><h3>Results</h3><div>Patients with sRV were characterized by lower systolic function assessed by TAPSE, s’, FAC, GLS both at baseline and at peak exercise, compared with the control group. sRV GLS decreased during exercise in patients with sRV (−6 + 2.84) compared to increased in patients with systemic left ventricle (0.47 + 2.74), p &lt; 0.001. There was no increase in VTI during exercise in patients with sRV, compared to controls (Δ VTI −0.01 ± 2.96 cm vs. Δ VTI 4.50 ± 3.13 cm, p &lt; 0.001). There was a trend towards higher chronotropic incompetence in patients with sRV vs. control (61% vs. 45%, p = 0.28).</div></div><div><h3>Conclusion</h3><div>Our results confirmed that patients with dTGA have reduced ability to increase myocardial contractility and stroke volume during exercise. Chronotropic incompetence was prevalent in dTGA patients.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 57-62"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chylopericardium after cardiac surgery: a rare yet serious complication","authors":"Kiriaki Mavromoustakou ,&nbsp;Emilia Lazarou ,&nbsp;Kyriakos Dimitriadis ,&nbsp;Vasiliki Oikonomou ,&nbsp;Sophia Vaina ,&nbsp;Christos Kaskoutis ,&nbsp;George Lazaros ,&nbsp;Costas Tsioufis","doi":"10.1016/j.hjc.2025.05.004","DOIUrl":"10.1016/j.hjc.2025.05.004","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 112-113"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Central versus peripheral VA ECMO for cardiogenic shock: an 8-year experience of a tertiary cardiac surgery center in Greece","authors":"Michael Antonopoulos ,&nbsp;Antigone Koliopoulou ,&nbsp;Dimitrios Elaiopoulos ,&nbsp;Kyriaki Kolovou ,&nbsp;Dimitra Doubou ,&nbsp;Anna Smyrli ,&nbsp;Prodromos Zavaropoulos ,&nbsp;Nektarios Kogerakis ,&nbsp;Sokratis Fragoulis ,&nbsp;Konstantinos Perreas ,&nbsp;Georgios Stavridis ,&nbsp;Stamatis Adamopoulos ,&nbsp;Themistocles Chamogeorgakis ,&nbsp;Stavros Dimopoulos","doi":"10.1016/j.hjc.2024.09.006","DOIUrl":"10.1016/j.hjc.2024.09.006","url":null,"abstract":"<div><h3>Background</h3><div>Venoarterial extracorporeal membrane oxygenation (VA ECMO) has emerged as an effective rescue therapy in patients with cardiogenic shock refractory to standard treatment protocols, and its use has been rising worldwide in the last decade. Although experience and availability are growing, outcomes remain poor. There is need for evidence to improve clinical practice and outcomes.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed the medical records of all patients who were supported with VA ECMO for cardiogenic shock at our institution between January 2015 and January 2023. The study purpose was to compare outcomes between patients who were supported with central versus peripheral configuration.</div></div><div><h3>Results</h3><div>ECMO was applied in 108 patients, 48 (44%) of whom received central configuration and 60 (56%) peripheral. Patients supported with central VA ECMO were more likely to be supported for post-cardiotomy shock (odds ratio [OR] 4.6 [95% confidence interval (CI) 2.03–10.41]), while patients in the peripheral group were predominantly treated for chronic heart failure decompensation (OR 9.4 [95% CI 1.16–76.3]). Central VA ECMO had lower survival rates during ECMO support (29.2% versus 51.7%, p = 0.018) and at discharge (8% versus 37%, p = 0.001). These patients were at high risk of complications, such as acute kidney injury (AKI) (OR 2.37 [95% CI 1.06–5.3], p = 0.034) and major bleeding (OR 3.08 [95% CI 1.36–6.94], p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Patients on central VA ECMO were supported mainly for post-cardiotomy shock, presented with more complications such as major bleeding and AKI, and had worse survival to hospital discharge compared with patients on peripheral VA ECMO. Patient selection, timing of implementation, cannulation strategy, and configuration remain the main determinants of clinical outcome.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 13-20"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Better performance of the APPLE score for the prediction of very early atrial fibrillation recurrence post-ablation","authors":"Wenchao Huang ,&nbsp;Huaxin Sun ,&nbsp;Yan Luo ,&nbsp;Shiqiang Xiong ,&nbsp;Yan Tang ,&nbsp;Yu Long ,&nbsp;Zhen Zhang ,&nbsp;Hanxiong Liu","doi":"10.1016/j.hjc.2024.08.008","DOIUrl":"10.1016/j.hjc.2024.08.008","url":null,"abstract":"<div><h3>Objective</h3><div>The benefits of rhythm control in early atrial fibrillation (AF) are increasingly recognized. This study aimed to investigate whether early AF ablation contributes to long-term sinus rhythm maintenance and to identify a suitable predictive score.</div></div><div><h3>Methods</h3><div>According to diagnosis-to-ablation time, this study prospectively enrolled 245 patients with very early AF, 262 with early AF, and 588 with late AF for radiofrequency ablation from June 2017 to December 2022. Clinical data, risk scores, and follow-up results were collected and analyzed.</div></div><div><h3>Results</h3><div>Baseline characteristics were similar among the three cohorts. During a median follow-up period of 26 months, AF recurrence was observed in 61 (24.9%), 66 (25.2%), and 216 (36.7%) patients in the very early, early, and late AF cohorts, respectively. In the multivariable-adjusted model, very early and early AF were associated with a reduced risk of AF recurrence, with hazard ratios of 0.72 (95% confidence interval [CI] 0.52–0.99) and 0.57 (95% CI 0.41–0.78), respectively. The APPLE score demonstrated the highest predictive power for very early AF, with an area under the curve (AUC) of 0.74. However, its predictive power decreased with time from diagnosis, showing low predictive power for late AF (AUC = 0.58). In addition, the time-dependent concordance index showed consistent results. For very early AF, the Akaike information criterion and decision curve analysis showed that APPLE had the highest predictive value.</div></div><div><h3>Conclusion</h3><div>Very early AF ablation was associated with a lower recurrence rate, and the APPLE score provided a higher predictive value for these patients. (URL: <span><span>https://www.chictr.org.cn/</span><svg><path></path></svg></span>; Unique identifier: ChiCTR-OIN-17013021)</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 36-48"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and anxiety in Greek patients who received an implantable cardioverter-defibrillator and did not have shock therapy during a 12-month follow-up","authors":"Sofia Plakoutsi ,&nbsp;Dimitrios Sfairopoulos ,&nbsp;Elizabeth Florou ,&nbsp;Aris Bechlioulis ,&nbsp;Konstantinos Zekios ,&nbsp;Haralampos Milionis ,&nbsp;Petros Skapinakis ,&nbsp;Panagiotis Korantzopoulos","doi":"10.1016/j.hjc.2025.05.005","DOIUrl":"10.1016/j.hjc.2025.05.005","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 97-100"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fast & furious: the acceleration of randomized clinical trials in contemporary cardiovascular medicine","authors":"Charalambos Vlachopoulos ,&nbsp;George Giannakoulas","doi":"10.1016/j.hjc.2026.03.003","DOIUrl":"10.1016/j.hjc.2026.03.003","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 1-3"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147489208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter repair for functional mitral regurgitation in heart failure: a time-to-event meta-analysis of randomized trials","authors":"Dimitrios E. Magouliotis ,&nbsp;Alexandros Briasoulis ,&nbsp;Basel Ramlawi ,&nbsp;Serge Sicouri ,&nbsp;Grigorios Giamouzis ,&nbsp;Thanos Athanasiou ,&nbsp;Randall C. Starling ,&nbsp;John Skoularigis ,&nbsp;Andrew Xanthopoulos","doi":"10.1016/j.hjc.2025.05.009","DOIUrl":"10.1016/j.hjc.2025.05.009","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"88 ","pages":"Pages 101-103"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}