Hellenic Journal of Cardiology最新文献

筛选
英文 中文
The role of bystander CPR in out-of-hospital cardiac arrest: what the evidence tells us 旁观者 CPR 在院外心脏骤停中的作用:证据告诉我们什么?
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2024.09.002
Natália C. Oliveira , Hugo Oliveira , Thamires L.C. Silva , Maria Boné , Jorge Bonito
{"title":"The role of bystander CPR in out-of-hospital cardiac arrest: what the evidence tells us","authors":"Natália C. Oliveira ,&nbsp;Hugo Oliveira ,&nbsp;Thamires L.C. Silva ,&nbsp;Maria Boné ,&nbsp;Jorge Bonito","doi":"10.1016/j.hjc.2024.09.002","DOIUrl":"10.1016/j.hjc.2024.09.002","url":null,"abstract":"<div><div>Out-of-hospital cardiac arrest (OHCA) is a global public health problem. Lay bystanders witness almost half of OHCA, so early recognition is critical to allow immediate initiation of cardiopulmonary resuscitation (CPR) by the bystander. The present investigation aims to analyze the most recent scientific evidence of the effect of bystander CPR on survival after an OHCA. A systematic literature review was carried out at the “Web of Science,” “Scopus,” and “PubMed” databases, including publications from the last 20 years. After inclusion/exclusion criteria, 37 articles were identified. Results indicate that patients who receive CPR are more likely to survive than those who don’t, and CPR is associated with a good quality of life post-OHCA. Emphasis should be placed on practicing chest compressions only when the bystander has not mastered the artificial ventilation technique. Finding an AED is the first step to using it in an OHCA situation. Correct use of an AED by laypeople is associated with nearly double the survival rate after an OHCA when compared to standard CPR. It is important to promote CPR and AED training to non-professionals, such as community residents and youth, as training is associated with higher success rates of effective CPR-AED. A mobile phone positioning system to recruit trained laypeople or text message alerts to send citizen volunteers as well as assistance through a mobile app appear to have significant advantages in practicing effective CPR. The benefits of bystander CPR outweigh the risk of injury to victims, highlighting the need to disseminate training to laypeople.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 86-98"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Why does cardiology have many extreme publishing authors?
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2025.01.005
John P.A. Ioannidis
{"title":"Why does cardiology have many extreme publishing authors?","authors":"John P.A. Ioannidis","doi":"10.1016/j.hjc.2025.01.005","DOIUrl":"10.1016/j.hjc.2025.01.005","url":null,"abstract":"<div><div>Under diverse contributing factors in different scientific micro-environments, the number of authors who publish extreme numbers of full articles in a single year has increased. Cardiology is the subfield that has the largest share of authors with extreme publishing behavior than any other subfield in science (outside physics). Between 2000 and 2022, 137 authors in the subfield of Cardiovascular System (CVS, Science-Metrix classification) have published over 60 full articles in at least one calendar year and are also highly cited. The majority (70/137) are from Europe. All 7 countries with the highest prevalence of CVS extreme publishing authors per million population are European countries. Issues of massive authorship of papers by administrative leaders are discussed, including the arguments in favor of sustaining this practice and a refutation of these arguments. Other major contributors to the phenomenon are publications from clinical trials and epidemiological studies and massive authorship of highly cited guidelines. Micro-environments are instrumental in creating extreme publishing behavior in both developed and less developed countries. Listing of contributions does not solve the problem since contributions are also gamed; metrics that probe gaming are nevertheless available. Eventually, authorship carries both credit and accountability. The number of publications is a metric that can be heavily gamed. Emphasis should be given to what makes a major impact on science and human lives.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 107-111"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The importance of intensive follow-up and achieving optimal chronic antithrombotic treatment in hospitalized medical patients with anemia: A prospective cohort study 强化随访和实现最佳慢性抗血栓治疗对住院内科贫血患者的重要性:一项前瞻性队列研究
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2023.12.006
Andria Papazachariou , John A. Papadakis , Vironas Malikides , Vasiliki Theodorakopoulou , George Vougiouklakis , Onoufrios Malikides , Diamantis P. Kofteridis
{"title":"The importance of intensive follow-up and achieving optimal chronic antithrombotic treatment in hospitalized medical patients with anemia: A prospective cohort study","authors":"Andria Papazachariou ,&nbsp;John A. Papadakis ,&nbsp;Vironas Malikides ,&nbsp;Vasiliki Theodorakopoulou ,&nbsp;George Vougiouklakis ,&nbsp;Onoufrios Malikides ,&nbsp;Diamantis P. Kofteridis","doi":"10.1016/j.hjc.2023.12.006","DOIUrl":"10.1016/j.hjc.2023.12.006","url":null,"abstract":"<div><h3>Background</h3><div>Anemia is a global health concern, particularly among the elderly on chronic antithrombotic treatment. Close monitoring of hemoglobin (Hb) levels and achievement of an optimized treatment significantly enhance patients’ quality of life. This study aimed to examine the impact of antithrombotic treatment on Hb levels and readmissions in hospitalized patients with anemia.</div></div><div><h3>Methods</h3><div>This is a prospective cohort study of patients admitted to the Department of Internal Medicine of the University Hospital of Heraklion, Greece, from November 2021 to October 2022 with the diagnosis of anemia while receiving antithrombotic treatment. Data regarding demographics, past medical history, and laboratory and endoscopy findings were recorded. For those receiving inappropriate therapy according to international guidelines, antithrombotic treatment was optimized. Subsequent follow-ups occurred at one and six months post-discharge. Six- and twelve-month anemia-caused readmissions, as well as annual mortality, were evaluated.</div></div><div><h3>Results</h3><div>In total, 104 patients were assessed. Among them, 34.6% were on antiplatelets, 56.7% were on anticoagulants, and 8.7% were on combination treatment. The mean age was 80 ± 8.2 years, and 54.8% were males. On admission, mean Hb levels were 6.86 ± 1.23 g/dL, while 56 (53.8%) patients had severe anemia. Gastroscopy and colonoscopy were performed in 75.0% and 41.4% of patients, respectively, confirming gastrointestinal bleeding in most of the cases. Treatment optimization was carried out for 56 patients. Follow-up revealed elevated Hb levels after one and six months post-discharge, while anemia-related readmissions stayed below 10%.</div></div><div><h3>Conclusions</h3><div>Most hospitalized anemic patients on antithrombotic treatment had endoscopic findings favoring gastrointestinal bleeding. Half received inappropriate antithrombotic therapy. Treatment optimization and regular follow-up improved Hb levels and reduced readmissions<strong>.</strong></div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 66-73"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139092354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atavism as a cause of dilative cardiomyopathy 作为扩张型心肌病病因的先天遗传。
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2024.03.015
Fabian Fastenrath , Anoshirwan Tavakoli , Daniel Duerschmied , Dariusch Haghi , Isabelle Ayx , Theano Papavassiliu
{"title":"Atavism as a cause of dilative cardiomyopathy","authors":"Fabian Fastenrath ,&nbsp;Anoshirwan Tavakoli ,&nbsp;Daniel Duerschmied ,&nbsp;Dariusch Haghi ,&nbsp;Isabelle Ayx ,&nbsp;Theano Papavassiliu","doi":"10.1016/j.hjc.2024.03.015","DOIUrl":"10.1016/j.hjc.2024.03.015","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 112-113"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141538966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shocking and inhumane inequalities. The gender gaps in Cardiology 令人震惊和不人道的不平等。心脏病学中的性别差距
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2025.03.008
Charalambos Vlachopoulos, Katerina Naka
{"title":"Shocking and inhumane inequalities. The gender gaps in Cardiology","authors":"Charalambos Vlachopoulos,&nbsp;Katerina Naka","doi":"10.1016/j.hjc.2025.03.008","DOIUrl":"10.1016/j.hjc.2025.03.008","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 1-2"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143759204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of 3-month dapagliflozin on left atrial function in treatment-naïve patients with type 2 diabetes mellitus: Assessment using 4-dimensional echocardiography 为期3个月的达帕格列净对未经治疗的2型糖尿病患者左心房功能的影响:使用四维超声心动图进行评估
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2023.12.002
Miao Zhang , Lanlan Sun , Xiaopeng Wu , Yunyun Qin , Mingming Lin , Xueyan Ding , Weiwei Zhu , Zhe Jiang , Shan Jin , Chenlei Leng , Jiangtao Wang , Xiuzhang Lv , Qizhe Cai
{"title":"Effects of 3-month dapagliflozin on left atrial function in treatment-naïve patients with type 2 diabetes mellitus: Assessment using 4-dimensional echocardiography","authors":"Miao Zhang ,&nbsp;Lanlan Sun ,&nbsp;Xiaopeng Wu ,&nbsp;Yunyun Qin ,&nbsp;Mingming Lin ,&nbsp;Xueyan Ding ,&nbsp;Weiwei Zhu ,&nbsp;Zhe Jiang ,&nbsp;Shan Jin ,&nbsp;Chenlei Leng ,&nbsp;Jiangtao Wang ,&nbsp;Xiuzhang Lv ,&nbsp;Qizhe Cai","doi":"10.1016/j.hjc.2023.12.002","DOIUrl":"10.1016/j.hjc.2023.12.002","url":null,"abstract":"<div><h3>Background</h3><div>The sodium-glucose transporter-2 (SGLT-2) inhibitor dapagliflozin can improve left ventricular (LV) performance in patients with type 2 diabetes mellitus (T2DM). However, the effects on left atrial (LA) function in treatment-naïve T2DM patients remain unclear. The aim of our study was 1) to investigate the effects of 3-month treatment with dapagliflozin on LA function in treatment-naïve patients with T2DM using 4-dimensional automated LA quantification (4D Auto LAQ) and 2) to explore linked covariation patterns of changes in clinical and LA echocardiographic variables.</div></div><div><h3>Methods</h3><div>4D Auto LAQ was used to evaluate LA volumes, longitudinal and circumferential strains in treatment-naïve T2DM patients at baseline, at follow-up, and in healthy control (HC). Sparse canonical correlation analysis (sCCA) was performed to capture the linked covariation patterns between changes in clinical and LA echocardiographic variables within the treatment-naïve T2DM patient group.</div></div><div><h3>Results</h3><div>This study finally included 61 treatment-naïve patients with T2DM without cardiovascular disease and 39 healthy controls (HC). Treatment-naïve T2DM patients showed reduced LA reservoir and conduit function at baseline compared to HC, independent of age, sex, BMI, and blood pressure (LASr: 21.11 ± 5.39 vs. 27.08 ± 5.31 %, <em>p</em><sub><em>adjusted</em></sub> = 0.017; LAScd: −11.51 ± 4.48 vs. −16.74 ± 4.51 %, <em>p</em><sub><em>adjusted</em></sub> = 0.013). After 3-month treatment with dapagliflozin, T2DM patients had significant improvements in LA reservoir and conduit function independent of BMI and blood pressure changes (LASr: 21.11 ± 5.39 vs. 23.84 ± 5.74 %, <em>p</em><sub><em>adjusted</em></sub> &lt; 0.001; LAScd: −11.51 ± 4.48 vs. −12.75 ± 4.70 %, <em>p</em><sub><em>adjusted</em></sub> &lt; 0.001). The clinical and LA echocardiographic parameters showed significant covariation (<em>r</em> = 0.562, <em>p</em> = 0.039). In the clinical dataset, changes in heart rate, insulin, and BMI were most associated with the LA echocardiographic variate. In the LA echocardiographic dataset, changes in LAScd, LASr, and LASr_c were most associated with the clinical variate.</div></div><div><h3>Conclusion</h3><div>Compared with HC, treatment-naïve patients with T2DM had lower LA function, and these patients benefited from dapagliflozin administration, particularly in LA function.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 43-53"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138629749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Results of systematic patient outcome monitoring: Does post-dilatation during angiography-guided percutaneous coronary intervention improve clinical outcomes? 血管造影引导下经皮冠状动脉介入治疗中扩张后是否能改善临床结果?-系统的患者预后监测结果。
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2023.11.004
Stacey R. Slingerland , Konrad A.J. van Beek , Daniela N. Schulz , Gijs J. van Steenbergen , Tim Brouwer , Martin Stoel , Pieter-Jan Vlaar , Pim A. Tonino , Lukas Dekker , Lokien X. van Nunen , Koen Teeuwen , Dennis van Veghel
{"title":"Results of systematic patient outcome monitoring: Does post-dilatation during angiography-guided percutaneous coronary intervention improve clinical outcomes?","authors":"Stacey R. Slingerland ,&nbsp;Konrad A.J. van Beek ,&nbsp;Daniela N. Schulz ,&nbsp;Gijs J. van Steenbergen ,&nbsp;Tim Brouwer ,&nbsp;Martin Stoel ,&nbsp;Pieter-Jan Vlaar ,&nbsp;Pim A. Tonino ,&nbsp;Lukas Dekker ,&nbsp;Lokien X. van Nunen ,&nbsp;Koen Teeuwen ,&nbsp;Dennis van Veghel","doi":"10.1016/j.hjc.2023.11.004","DOIUrl":"10.1016/j.hjc.2023.11.004","url":null,"abstract":"<div><h3>Objectives</h3><div>This study evaluates clinical outcomes after implementing a liberal post-dilatation strategy during PCI.</div></div><div><h3>Background</h3><div>Post-dilatation after percutaneous coronary intervention (PCI) is performed to achieve optimal stent expansion and reduce complications. However, its prognostic effects are unclear and conflicting.</div></div><div><h3>Methods</h3><div>This study is a pre-post-intervention analysis of two cohorts, before (2015-2017) and after (2018-2020) implementation of a liberal post-dilatation strategy. The primary end point consisted of major adverse cardiovascular events (MACE) at 30 days. Secondary end points consisted of the individual components of the primary end point as well as 1 year mortality and target vessel revascularization.</div></div><div><h3>Results</h3><div>A total of 10,153 patients were included: 5,383 in the pre-cohort and 4,770 in the post-cohort. The 30-day MACE was 5.00% in the pre-cohort and 4.09% in the post-cohort (<em>p</em> = 0.008; OR 0.75 (CI 0.61-0.93)). There was a significant difference between the pre- and post-cohort in 30-day mortality, respectively, 2.91% and 2.25% (<em>p</em> = .01; OR 0.70 (CI 0.53-0.93)), and MI at 30 days, 1.17% versus 0.59% (<em>p</em> = .003; OR 0.49 (CI 0.31-0.78)). At 1 year, there was a significant difference in mortality between the pre-cohort, 5.84%, and post-cohort, 5.19% (<em>p</em> = .02; OR 0.79 (CI 0.66-0.96)).</div></div><div><h3>Conclusions</h3><div>A liberal post-dilatation strategy after PCI was associated with a significant decrease in 30-day MACE, 30-day MI, 30-day mortality, and 1-year mortality. Future studies are warranted to validate the causality between post-dilatation and improvement of clinical outcomes.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 26-33"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morbidity and mortality trends in patients with inflammatory bowel disease presenting with ST elevation myocardial infarction 出现 ST 段抬高型心肌梗死的炎症性肠病患者的发病率和死亡率趋势。
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2024.07.005
Magdi Zordok , Sourbha S. Dani , Mariam Tawadros , Hady T. Lichaa , Jimmy L. Kerrigan , Babar Basir , Khaldoon Alaswad , Michael Miedema , Michael Megaly
{"title":"Morbidity and mortality trends in patients with inflammatory bowel disease presenting with ST elevation myocardial infarction","authors":"Magdi Zordok ,&nbsp;Sourbha S. Dani ,&nbsp;Mariam Tawadros ,&nbsp;Hady T. Lichaa ,&nbsp;Jimmy L. Kerrigan ,&nbsp;Babar Basir ,&nbsp;Khaldoon Alaswad ,&nbsp;Michael Miedema ,&nbsp;Michael Megaly","doi":"10.1016/j.hjc.2024.07.005","DOIUrl":"10.1016/j.hjc.2024.07.005","url":null,"abstract":"","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 103-106"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic impact of diabetes mellitus on in-hospital mortality in patients with acute myocardial infarction complicating renal dysfunction according to age and sex 糖尿病对急性心肌梗死合并肾功能不全患者住院死亡率的影响与年龄、性别的关系
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2023.11.002
Kenichi Matsushita , Sunao Kojima , Kyoko Hirakawa , Noriaki Tabata , Miwa Ito , Kenshi Yamanaga , Koichiro Fujisue , Tadashi Hoshiyama , Shinsuke Hanatani , Daisuke Sueta , Hisanori Kanazawa , Seiji Takashio , Yuichiro Arima , Satoshi Araki , Hiroki Usuku , Satoru Suzuki , Eiichiro Yamamoto , Taishi Nakamura , Hirofumi Soejima , Koichi Kaikita , Kenichi Tsujita
{"title":"Prognostic impact of diabetes mellitus on in-hospital mortality in patients with acute myocardial infarction complicating renal dysfunction according to age and sex","authors":"Kenichi Matsushita ,&nbsp;Sunao Kojima ,&nbsp;Kyoko Hirakawa ,&nbsp;Noriaki Tabata ,&nbsp;Miwa Ito ,&nbsp;Kenshi Yamanaga ,&nbsp;Koichiro Fujisue ,&nbsp;Tadashi Hoshiyama ,&nbsp;Shinsuke Hanatani ,&nbsp;Daisuke Sueta ,&nbsp;Hisanori Kanazawa ,&nbsp;Seiji Takashio ,&nbsp;Yuichiro Arima ,&nbsp;Satoshi Araki ,&nbsp;Hiroki Usuku ,&nbsp;Satoru Suzuki ,&nbsp;Eiichiro Yamamoto ,&nbsp;Taishi Nakamura ,&nbsp;Hirofumi Soejima ,&nbsp;Koichi Kaikita ,&nbsp;Kenichi Tsujita","doi":"10.1016/j.hjc.2023.11.002","DOIUrl":"10.1016/j.hjc.2023.11.002","url":null,"abstract":"<div><h3>Background</h3><div>Patients with acute myocardial infarction (AMI) complicating renal dysfunction (RD) are recognized as being at high risk. Although diabetes mellitus (DM) is a major cause of RD, the prognostic impact of coexisting DM on mortality in patients with AMI complicating RD is ill-defined. This study compared the prognostic impact of coexisting DM in patients with AMI complicating RD according to both age and sex.</div></div><div><h3>Methods</h3><div>A multicenter retrospective study was conducted on 2988 consecutive patients with AMI complicating RD (estimated glomerular filtration rate &lt;60 mL/min per 1.73 m<sup>2</sup>). Multivariable Cox regression analysis was performed to investigate the effects of DM on in-hospital mortality.</div></div><div><h3>Results</h3><div>Statistically significant interactions between age and DM and between sex and DM for in-hospital mortality were revealed in the entire cohort. Coexisting DM was identified as an independent risk factor for in-hospital mortality (hazard ratio [HR], 2.543) in young (aged &lt;65 years), but not old (aged ≥65 years), patients. DM was identified as an independent risk factor (HR, 1.469) in male, but not female, patients. Kaplan–Meier survival curves showed that DM correlated with significantly low survival rates in patients that were young or male as compared to those who were old or female.</div></div><div><h3>Conclusions</h3><div>There were significant differences in the prognostic impact of DM on in-hospital mortality between young and old as well as male and female patients with AMI complicating RD. These results have implications for future research and the management of patients with DM, RD, and AMI comorbidities.</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 15-25"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92157390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic effect of sex according to shock severity in patients with acute myocardial infarction complicated by cardiogenic shock 急性心肌梗死并发心源性休克患者休克严重程度对性别的预后影响
IF 2.7 3区 医学
Hellenic Journal of Cardiology Pub Date : 2025-03-01 DOI: 10.1016/j.hjc.2023.11.007
Yeji Kim , Woo Jin Jang , Ik hyun Park , Ju Hyeon Oh , Jeong Hoon Yang , Hyeon-Cheol Gwon , Chul-Min Ahn , Cheol Woong Yu , Hyun-Joong Kim , Jang-Whan Bae , Sung Uk Kwon , Hyun-Jong Lee , Wang Soo Lee , Jin-Ok Jeong , Sang-Don Park
{"title":"Prognostic effect of sex according to shock severity in patients with acute myocardial infarction complicated by cardiogenic shock","authors":"Yeji Kim ,&nbsp;Woo Jin Jang ,&nbsp;Ik hyun Park ,&nbsp;Ju Hyeon Oh ,&nbsp;Jeong Hoon Yang ,&nbsp;Hyeon-Cheol Gwon ,&nbsp;Chul-Min Ahn ,&nbsp;Cheol Woong Yu ,&nbsp;Hyun-Joong Kim ,&nbsp;Jang-Whan Bae ,&nbsp;Sung Uk Kwon ,&nbsp;Hyun-Jong Lee ,&nbsp;Wang Soo Lee ,&nbsp;Jin-Ok Jeong ,&nbsp;Sang-Don Park","doi":"10.1016/j.hjc.2023.11.007","DOIUrl":"10.1016/j.hjc.2023.11.007","url":null,"abstract":"<div><h3>Background</h3><div>Sex disparities in cardiogenic shock (CS) treatment are controversial, and the prognostic implications of sex remain unclear in CS caused by acute myocardial infarction (AMI).</div></div><div><h3>Objectives</h3><div>This study aimed to evaluate the prognostic effect of sex according to the severity of CS in patients undergoing percutaneous coronary intervention (PCI) for AMI complicated by CS.</div></div><div><h3>Methods</h3><div>We assessed 695 patients from 12 tertiary centers in South Korea who underwent PCI for AMI complicated by CS, and analyzed outcomes by sex (female [n = 184] vs. male [n = 511]). We compared a 12-month patient-oriented composite endpoint (POCE, defined as a composite of all-cause mortality, myocardial infarction, re-hospitalization due to heart failure, and repeat revascularization) between the sexes, respective of SCAI shock stage C&amp;D or E. Propensity score-matched analysis was performed to reduce bias.</div></div><div><h3>Results</h3><div>We found that the female group was older and had higher vasoactive-inotropic and IABP-SHOCK II scores than the male group, with findings consistent across SCAI shock stages. During the 12-month follow-up period, multivariate analysis revealed no significant differences in POCE (HR 1.01, 95% CI 0.67–1.53, <em>p</em> = 0.963 for SCAI stage C&amp;D, HR 1.24, 95% CI 0.84–1.84, <em>p</em> = 0.286 for SCAI stage E) between females and males. After propensity score matching, the incidence of POCE (HR 1.47, 95% CI 0.79–2.72, <em>p</em> = 0.220 for SCAI stage C&amp;D, HR 0.88, 95% CI 0.49–1.57, <em>p</em> = 0.665 for SCAI stage E) was similar between sexes.</div></div><div><h3>Conclusions</h3><div>Sex does not appear to influence the risk of 12-month POCE in patients treated with PCI for CS caused by AMI, irrespective of shock severity.</div></div><div><h3>Clinical Trial Registration</h3><div><span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> NCT02985008. RESCUE (REtrospective and prospective observational Study to investigate Clinical oUtcomes and Efficacy of left ventricular assist device for Korean patients with cardiogenic shock), NCT02985008, Registered December 5, 2016 - retrospectively and prospectively.</div></div><div><h3>IRB Information</h3><div>This study was approved by the institutional review board of Samsung Medical Center (Reference number: 2016-03-130).</div></div>","PeriodicalId":55062,"journal":{"name":"Hellenic Journal of Cardiology","volume":"82 ","pages":"Pages 3-14"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138629047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信