Journal of Ect最新文献_第4页

Electroconvulsive Therapy in the Treatment of Clinical Zoanthropy With Comorbid Parkinson's Disease: A Case Report. 电休克疗法治疗临床人畜共病帕金森病1例报告。

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-05-22 DOI: 10.1097/YCT.0000000000001160

Lore Van de Voorde, Pieter-Jan Geerts, Gilbert Lemmens

引用次数: 0

Comparison of the Effects of Dexmedetomidine and Remifentanil on Seizure Duration, Hemodynamics, and Recovery Time in Electroconvulsive Therapy. 右美托咪定和瑞芬太尼对电休克患者癫痫发作时间、血流动力学和恢复时间的影响比较。

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-05-20 DOI: 10.1097/YCT.0000000000001161

Irem Durmus, Ozlem Sezen, Banu Cevik, Merih Altintas

{"title":"Comparison of the Effects of Dexmedetomidine and Remifentanil on Seizure Duration, Hemodynamics, and Recovery Time in Electroconvulsive Therapy.","authors":"Irem Durmus, Ozlem Sezen, Banu Cevik, Merih Altintas","doi":"10.1097/YCT.0000000000001161","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001161","url":null,"abstract":"Objectives: Electroconvulsive therapy (ECT) is an important treatment method that is widely used in psychiatric conditions resistant to pharmacological treatments.Methods: This prospective, randomized study included 100 patients undergoing ECT. Group D received dexmedetomidine and propofol, while group R received remifentanil and propofol. In this study, key parameters such as seizure duration, hemodynamic changes, and recovery time were analyzed.Results: The investigation revealed no statistically significant differences between the groups with regard to mean age, gender distribution, or seizure duration (P > 0.05). Subsequent to induction, group R exhibited statistically significantly lower systolic blood pressure, diastolic blood pressure, and mean arterial pressures in comparison to group D (P < 0.05). Conversely, heart rate, systolic blood pressure, diastolic blood pressure, and mean arterial pressure levels in group R were found to be statistically significantly higher than in group D (P < 0.05). The recovery time in group D was found to be statistically significantly longer than in group R (P < 0.05).Conclusions: Dexmedetomidine provides superior hemodynamic stability, while remifentanil ensures faster recovery. Dexmedetomidine has been shown to be more advantageous in terms of hemodynamic stability, while remifentanil has been demonstrated to result in shorter recovery times. Clinicians should tailor anesthetic choices based on patient profiles and therapeutic goals.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electroconvulsive Therapy Changes Peripheral Blood Neurotrophic and Inflammatory Markers in Depressed Patients. 电惊厥治疗改变抑郁症患者外周血神经营养和炎症标志物。

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-05-12 DOI: 10.1097/YCT.0000000000001139

Nadia Falhani, Lisa-Marie Brunner, Doris Melchner, Jens Volkmar Schwarzbach, Rainer Rupprecht, Caroline Nothdurfter

{"title":"Electroconvulsive Therapy Changes Peripheral Blood Neurotrophic and Inflammatory Markers in Depressed Patients.","authors":"Nadia Falhani, Lisa-Marie Brunner, Doris Melchner, Jens Volkmar Schwarzbach, Rainer Rupprecht, Caroline Nothdurfter","doi":"10.1097/YCT.0000000000001139","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001139","url":null,"abstract":"Background: Electroconvulsive therapy (ECT) is one of the most effective treatments for treatment-resistant depression, yet its precise mechanisms of action remain to be further elucidated. Among other effects, ECT induces an acute inflammatory immune response that might reinforce the expression of neurotrophins such as brain-derived neurotrophic factor (BDNF). The aim of this study is to unveil the potentially beneficial role of inflammation observed during ECT.Methods: Within a repeated measures design study of 6 weeks, 9 patients diagnosed with depressive disorder received 3 ECT sessions per week. We tracked the clinical progress using the Hamilton Depression rating scale (HAMD-21) and Beck's depression inventory. By collecting peripheral blood samples before and throughout the entire course of ECT, we investigated week-by-week changes in inflammation markers such as IL-6, IL-1β, TNF-α, and IL-4, serum BDNF, and cortisol levels.Results: Seven out of 9 patients successfully responded to ECT according to HAMD-21 scores. Serum BDNF levels progressively increased during the ECT series, and negatively correlated with HAMD-21 scores. TNF-α levels increased until week 4 and decreased after the end of the therapy. Moreover, we found altered expression of the anti-inflammatory cytokine IL-4, while serum cortisol levels did not change during ECT.Conclusions: The initial activation of the immune-inflammatory response observed during ECT may be beneficial for therapeutic effects, as it is related to a long-term stimulation of BDNF, which enhances neuronal plasticity. The downregulation of proinflammatory markers after the end of the ECT series may be associated with clinical improvement.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cranial Sutures Alter Computational Models of Transcranial Electrical Stimulation. 颅缝改变经颅电刺激的计算模型。

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-05-02 DOI: 10.1097/YCT.0000000000001154

Alistair Carroll, Caroline Rae, Donel Martin, Socrates Dokos, Colleen Loo

{"title":"Cranial Sutures Alter Computational Models of Transcranial Electrical Stimulation.","authors":"Alistair Carroll, Caroline Rae, Donel Martin, Socrates Dokos, Colleen Loo","doi":"10.1097/YCT.0000000000001154","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001154","url":null,"abstract":"Background: ROAST (Realistic vOlumetric-Approach-based Simulator for Transcranial electric stimulation) has been increasingly utilized to inform studies of transcranial electrical stimulation (tES). The precision of ROAST is dependent on anatomical accuracy.Objectives: The aims of the study were to compare using only T1 magnetic resonance images in ROAST (T1 model), with a combination of T1 and T2 magnetic resonance images (T1 and T2 model) and to model the electrical fields generated by tES with commonly used ECT montages: bitemporal, bifrontal, and right unilateral and varying the skull conductivities (based on the electrode position) and including cranial sutures.Methods: The \"T1 model\" was selected for computational modeling. The skull conductivity was varied from the \"default setting in ROAST\" (0.01S/m) to that of temporal bone (0.0038S/m) and frontal bone (0.0126S/m). \"Disc\" electrodes (5 cm in diameter) were applied with 1 mA of current. \"Pad\" electrodes, 0.1 mm high and 40 mm wide, were positioned over the squamous suture, coronal suture and sagittal suture and the skull conductivity changed to approximate suture conductivity (0.32S/m).Results: The \"T1 model\" differed from the \"T1 and T2 model,\" which resulted in variable electric fields reaching individual tissue layers. Changing skull conductivity and simulating the cranial sutures resulted in changes to the electric current reaching the cortical and subcortical structures with the later having a greater impact.Conclusions: This study demonstrates the importance of anatomically accurate head models in ROAST computational modeling of tES. Varying the skull conductivity based on studies in vivo and including cranial sutures is imperative for more realistic predictions of electric field and reproducibility.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Introduction of Electroconvulsive Therapy in Cameroon. 喀麦隆引进电休克疗法。

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-05-01 DOI: 10.1097/YCT.0000000000001156

Michael Guy Toguem, Ikenna D Ebuenyi

引用次数: 0

Venlafaxine During Electroconvulsive Therapy Is Associated With the Postictal Administration of Antihypertensive Medication. 电惊厥治疗期间文拉法辛与后给药降压药物有关。

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-04-29 DOI: 10.1097/YCT.0000000000001157

Sebastian Karl, Jonathan Reinwald, Susanne Berger, Alexander Sartorius, Suna Su Aksay

{"title":"Venlafaxine During Electroconvulsive Therapy Is Associated With the Postictal Administration of Antihypertensive Medication.","authors":"Sebastian Karl, Jonathan Reinwald, Susanne Berger, Alexander Sartorius, Suna Su Aksay","doi":"10.1097/YCT.0000000000001157","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001157","url":null,"abstract":"Introduction: Electroconvulsive therapy (ECT) is a highly effective treatment for severe depression and commonly administered with concomitant antidepressant medication. ECT is associated with short-lived and self-limiting changes in blood pressure. Thus, additional medications that potentially elevate blood pressure, such as antidepressants with noradrenergic effects, might be of special concern during ECT.Methods: We retrospectively analyzed data from patients in which the same patient received some ECT sessions with and some without concomitant venlafaxine medication. To assess whether concomitant venlafaxine medication increased the likelihood that patients required antihypertensive medication after ECT, we used mixed-effects logistic regression. We restricted our analysis to high-risk patients with at least 1 recorded systolic blood pressure >200 mmHg during their ECT series.Results: We identified 56 patients who received some of their ECT sessions with and some without concomitant venlafaxine, in total 1173 ECT treatments. Among these, 40 patients had at least 1 systolic blood pressure measurement >200 mmHg. The 396 ECT treatments of these 40 patients were further analyzed. The odds for postictal administration of antihypertensive medication in the treatment room were significantly higher when patients received concomitant venlafaxine medication (odds ratio, 5.46; P = 0.015) and in older patients (OR, 3.28; P = 0.019).Conclusions: Concomitant venlafaxine medication could increase the likelihood that patients need antihypertensive medication during ECT treatment, especially patients at high risk for hypertension. Clinicians should be aware of this association and consider either adjusting the venlafaxine dose or adapting the timing of its administration during an ECT series.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Retrospective Study of Intraoperative Awareness in Patients Undergoing Electroconvulsive Therapy at Dartmouth Hitchcock Medical Center Over a 3-Year Period. 达特茅斯希区柯克医疗中心3年来接受电休克治疗患者术中意识的回顾性研究

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-04-28 DOI: 10.1097/YCT.0000000000001143

Marnie Bowen Welch, Daniela Armella Tangarife, Julia C Knight

{"title":"A Retrospective Study of Intraoperative Awareness in Patients Undergoing Electroconvulsive Therapy at Dartmouth Hitchcock Medical Center Over a 3-Year Period.","authors":"Marnie Bowen Welch, Daniela Armella Tangarife, Julia C Knight","doi":"10.1097/YCT.0000000000001143","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001143","url":null,"abstract":"Objective: At our academic institution, in a collaborative effort between the departments of anesthesiology, psychiatry, and nursing, we aimed to collect data about the incidence, nature, and predictive factors of intraoperative awareness in patients undergoing electroconvulsive therapy (ECT). Eligible patients were given modified Brice interviews, and the compliance rate of the interviews was analyzed and the effect of the educational initiatives put in place reviewed.Methods: Brice interviews were given to patients after ECT over a 3-year period, which included the education of staff. Data points were collected over this 3-year period via the electronic medical record for patients receiving ECT and those who were eligible to complete a Brice interview after procedure. Statistical analysis was conducted to meet our objectives.Results: The incidence of intraoperative awareness in our patients undergoing ECT was 4.7% (44 out of 936 interviews) and baseline characteristics were recorded. No predictors of intraoperative awareness were discovered. The nature of each positive interview was reviewed and put into categories, and anesthesia modification was reviewed for the positive interviews. Mental health after procedure was shown to be, by our measures, the same between patients with positive Brice interviews and patients with negative Brice interviews. The overall compliance rates of the modified Brice interview were analyzed, and to measure the impact of such initiatives, the compliance rates were compared before and after particular educational initiatives.Conclusions: Our study underscores the importance of tracking intraoperative awareness in patients receiving ECT, using Brice interviews in this population, and executing quality initiatives in the departments involved.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"To the Editor: Demonstrating Continued Safety With Right-Unilateral Electroconvulsive Therapy in a Patient With an Intracranial Implantable Device". 致编辑：在颅内植入装置的患者中证明右单侧电休克治疗的持续安全性。

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-04-28 DOI: 10.1097/YCT.0000000000001133

Justin J Pomeroy, Catherine Bledowski, Jozef Bledowski

引用次数: 0

Evaluation of the Efficacy of Electroconvulsive Therapy in Relation to the Anesthetic Agent Applied: A Retrospective Analysis. 电惊厥治疗与所用麻醉剂的疗效评价：回顾性分析。

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-04-28 DOI: 10.1097/YCT.0000000000001155

Selin Balki Tekin, Ayşe Nur İnci Kenar, İhsan Anıl Doğruyol, Özgür Tekin

{"title":"Evaluation of the Efficacy of Electroconvulsive Therapy in Relation to the Anesthetic Agent Applied: A Retrospective Analysis.","authors":"Selin Balki Tekin, Ayşe Nur İnci Kenar, İhsan Anıl Doğruyol, Özgür Tekin","doi":"10.1097/YCT.0000000000001155","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001155","url":null,"abstract":"Objectives: The present study aims to make a contribution to the extant literature on the sharing of clinical experiences with electroconvulsive therapy (ECT) and the effects of different anesthetic drugs on ECT efficacy.Methods: A retrospective analysis of the medical records of patients who were administered ECT from March 2023 to July 2024 was conducted to obtain data on age, gender, psychiatric diagnosis, type of psychiatric drugs used, the effectiveness of ECT, type of anesthetic agent administered during ECT, and the side effects after ECT.Results: A total of 149 patients were included in the study, of whom 81 (54.4%) were female and 68 (45.6%) were male, with a mean age of 41.72 years (±15.68). At least 1 side effect related to ECT was reported in 23 patients. When the number of effective sessions was analyzed according to the anesthetic agent used, the number of effective sessions of ECT was statistically significantly higher in patients who received ketamine alone than in patients who received propofol, propofol to ketamine, and propofol ketamine combination (P < 0.001, P < 0.001, P = 0.011, respectively). No significant relationship was found between the type of anesthetic agent and side effects (P = 0.059).Conclusions: The combination of ketamine and propofol may be regarded as a safer option in terms of side effects and cognitive functions when compared with their use in isolation. Furthermore, the utilization of ketamine as an anesthetic agent in patients exhibiting ineffective seizures can be regarded as a viable alternative strategy.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report: Rapid Improvement of Noncatatonic Mutism in a Patient With Schizophrenia by Electroconvulsive Therapy. 病例报告：电休克治疗可迅速改善精神分裂症患者的非紧张性缄默症。

IF 1.8 4区医学

Journal of Ect Pub Date : 2025-04-25 DOI: 10.1097/YCT.0000000000001153

Daniel Loeffler, Ilana Regenbogen-Li, Alan S Lewis

引用次数: 0