Journal of Ect最新文献_第4页

A Randomized Controlled Trial of Ultrabrief Right Unilateral ECT With Frontoparietal Versus Temporoparietal Electrode Placement for Severe Depression-The RAFT ECT Trial. 前顶叶与颞顶叶电极放置治疗严重抑郁症的超短右单侧电痉挛随机对照试验--RAFT ECT 试验。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 Epub Date: 2024-07-05 DOI: 10.1097/YCT.0000000000001018

Colleen Loo, Ana Rita Barreiros, Donel Martin, Vanessa Dong, Mark S George, William V McCall, Shanthi Sarma, Malcolm Hopwood, Alan Weiss, Michael Bull, Clara M Tuneu, Angelo Alonzo, Dusan Hadzi-Pavlovic, Anthony Rodgers, Gregory L Sahlem, Anna J Harvey, Kate Haldane, Louise Brettell, Paul B Fitzgerald, Socrates Dokos, Harold Sackeim

引用次数: 0

Flurothyl Inhalation Therapy: Resurrecting an Alternative to Electricity Induced Seizures. 氟乙烷吸入疗法：复活电击诱发癫痫的替代疗法。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 Epub Date: 2024-06-28 DOI: 10.1097/YCT.0000000000001033

Max Fink

引用次数: 0

Modified Electroconvulsive Therapy Normalizes Plasma GNA13 Following Schizophrenic Relapse. 改良电休克疗法可使精神分裂症复发后的血浆 GNA13 恢复正常

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 Epub Date: 2024-08-08 DOI: 10.1097/YCT.0000000000001050

Hongli Zhang, Hui Li, Mei Yu, Minglan Yu, Shuangshuang Feng, Wang Tingting, Yang Yu, Jin Zhang, Kezhi Liu, Youguo Tan, Bo Xiang

{"title":"Modified Electroconvulsive Therapy Normalizes Plasma GNA13 Following Schizophrenic Relapse.","authors":"Hongli Zhang, Hui Li, Mei Yu, Minglan Yu, Shuangshuang Feng, Wang Tingting, Yang Yu, Jin Zhang, Kezhi Liu, Youguo Tan, Bo Xiang","doi":"10.1097/YCT.0000000000001050","DOIUrl":"10.1097/YCT.0000000000001050","url":null,"abstract":"Objective: GNA13 is an important member of the G protein family, and its coding gene GNA13 has been identified as one of the risk genes for schizophrenia (SCZ). This study aimed to investigate the relationship between GNA13 levels and the clinical symptoms of SCZ following treatment with modified electroconvulsive therapy (MECT).Methods: This study recruited 82 SCZ patients and 86 healthy controls (HCs). Each SCZ patient received 6 sessions of MECT. The Positive and Negative Syndrome Scale (PANSS) was used to assess SCZ symptom severity. Plasma levels of GNA13 were measured by enzyme-linked immunosorbent assay.Results: Pretreatment, SCZ patients had a higher GNA13 level than HC ( t = 8.199, P < 0.001). MECT reduced the GNA13 level significantly ( t = 11.13, P < 0.001) and normalized the difference between SCZ and HC ( t = 0.219, P = 0.827). After treatment, the downregulation of GNA13 (ΔGNA13) was negatively correlated with the positive symptoms score reduction rate (ΔP) ( r = -0.379, P = 0.027) and positively correlated with the negative score reduction rate (ΔN) ( r = 0.480, P = 0.004) in females. In both males and females, the receiver operating characteristic curve revealed that the pretreatment GNA13 level could help differentiate SCZ from HC (male: area under the curve = 0.792, P < 0.001; female: area under the curve = 0.814, P < 0.001).Conclusion: The reduced expression of GNA13 after MECT may be related to the exhibition of both negative and positive symptoms of SCZ in female patients.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"286-292"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141910162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accelerated Continuous Theta Burst Stimulation in the Treatment of Trichotillomania: A Comprehensive Case Study From Acute Intervention to Maintenance Phase. 加速连续θ脉冲刺激治疗毛手毛脚症：从急性干预到维持阶段的综合案例研究》。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 Epub Date: 2024-03-21 DOI: 10.1097/YCT.0000000000001010

Priyanshi Chaudhary, Sujita Kumar Kar

引用次数: 0

Refractory Pediatric Catatonia Following Treatment for an Intracranial Mass: Safe and Effective Use of Electroconvulsive Therapy. 颅内肿块治疗后的难治性儿童紧张症：安全有效地使用电休克疗法。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 Epub Date: 2024-08-23 DOI: 10.1097/YCT.0000000000001066

Joshua Moss, Nadav Kastle, Lee Wolfrum, Pamela Bokat, Elizabeth Perry, Roslyn Gerwin

引用次数: 0

Safety and Efficacy of Modified Electroconvulsive Therapy in Managing Catatonic Symptoms in a Case of Suspected Marfan Syndrome With a Large Atrial Septal Defect. 改良电休克疗法在治疗一例疑似马凡氏综合征伴巨大心房间隔缺损病例的紧张性症状中的安全性和有效性

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 DOI: 10.1097/YCT.0000000000001073

Apurba Narayan Mahato, Natasha Patel, Satyanarayanprabhu Mudaliyar

引用次数: 0

Effectiveness and Safety of Flumazenil Augmentation During Electroconvulsive Therapy. 电休克治疗期间氟马西尼增强剂的有效性和安全性。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 Epub Date: 2024-02-12 DOI: 10.1097/YCT.0000000000001003

Lennart Gistelinck, Nele Van de Velde, Hannelore Tandt, Pieter Verslype, Gilbert Lemmens

{"title":"Effectiveness and Safety of Flumazenil Augmentation During Electroconvulsive Therapy.","authors":"Lennart Gistelinck, Nele Van de Velde, Hannelore Tandt, Pieter Verslype, Gilbert Lemmens","doi":"10.1097/YCT.0000000000001003","DOIUrl":"10.1097/YCT.0000000000001003","url":null,"abstract":"Introduction: Benzodiazepines are considered to negatively affect seizure quality and duration during electroconvulsive therapy (ECT). Several researchers have advocated the use of flumazenil, a competitive benzodiazepine receptor antagonist, for patients treated with benzodiazepines during ECT. However, clinical evidence regarding flumazenil use in ECT remains sparse. The aim of this study is to investigate the effects of flumazenil on seizure duration and adverse effects.Methods: All patients with depressive disorders, treated with flumazenil during a course of ECT in 2019 in a tertiary hospital, were identified through a retrospective chart review. Seizure duration was recorded before and after flumazenil administration. Effectiveness of ECT was assessed using the Inventory of Depressive Symptomatology and the Bush-Francis Catatonia Rating Scale. Postictal agitation was ascertained by identifying patients who received additional sedatives immediately after ECT or who needed physical restraint.Results: Twenty-six patients were included, receiving a total of 363 treatments, of which 263 were augmented with flumazenil. Flumazenil administration increased electroencephalogram seizure duration on average with 10.5 seconds comparing ECT with or without flumazenil ( P = 0.003). In 21.8% of the cases, no increase in seizure duration was observed. Postictal agitation occurred at least once in 34.6% of the patients receiving flumazenil during their course of ECT.Conclusion: Our results show that flumazenil increases seizure duration, albeit with limited clinical implications. Noteworthy, the prevalence of postictal agitation is high. When confronted with short seizures, clinicians should therefore deploy other available techniques to lower seizure threshold before considering flumazenil.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e49-e51"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139906937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editor's Roundup: Known Knowns, Known Unknowns, and Unknown Unknowns in ECT--Due Diligence and Preparation Are Sine Qua Nons of Practice; Machine Learning to Refine and Inform ECT Practice; the CARE Network Helps Drive Better Understanding of Treatment Variation to Improve Outcomes, Practice, Education, and Policy, Among Other Uses; Advocacy for ECT in Guidelines and in the Arts-A Reminder of Our Role. 编辑综述：ECT中的已知、已知和未知--尽职和准备是实践的必要条件；机器学习完善并指导ECT实践；CARE网络帮助人们更好地了解治疗差异，以改善治疗效果、实践、教育和政策等；在指南和艺术中倡导ECT--提醒我们的角色。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 DOI: 10.1097/YCT.0000000000001086

Randall T Espinoza

引用次数: 0

Electroconvulsive Therapy Changes Immunological Markers in Patients With Major Depressive Disorder: A Scoping Review. 电休克疗法会改变重度抑郁症患者的免疫标记物：范围综述。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 Epub Date: 2024-06-20 DOI: 10.1097/YCT.0000000000001021

Jonathan R Young, Mariah K Evans, Julie Hwang, Michael D Kritzer, Charles H Kellner, Richard D Weiner

{"title":"Electroconvulsive Therapy Changes Immunological Markers in Patients With Major Depressive Disorder: A Scoping Review.","authors":"Jonathan R Young, Mariah K Evans, Julie Hwang, Michael D Kritzer, Charles H Kellner, Richard D Weiner","doi":"10.1097/YCT.0000000000001021","DOIUrl":"10.1097/YCT.0000000000001021","url":null,"abstract":"Abstract: Major depressive disorder (MDD) is a highly prevalent and disabling condition. As such, understanding the causes of and treatment options for MDD is critical. Electroconvulsive therapy (ECT) remains the gold standard depression treatment, but the molecular mechanisms that underlie its effects are still largely unknown. One such explanation hinges on the immuno-inflammatory correlates of ECT treatment, given mounting evidence supporting the inflammatory hypothesis of depression. This review aims to provide an overview of the suggested immunomodulatory effects of ECT and the predictive value of immune biomarkers in relation to treatment outcomes and side effects. We conducted a preregistered, systematic literature search utilizing MEDLINE (PubMed), Embase (Elsevier), and PsycINFO (EBSCO) databases. We employed keywords related to MDD, ECT, gut microbiome, and the immune system. We only included human subjects research published between 1985 and January 13, 2021. Twenty-six unique studies were included in our analyses. Findings indicate a proinflammatory profile associated with MDD, with immune biomarkers exhibiting acute and chronic changes following ECT. Consistently, lower baseline interleukin 6 levels and higher C-reactive protein levels are correlated with a greater reduction in depressive symptoms following ECT. Furthermore, included studies emphasize the predictive value of peripheral immune changes, specifically interleukin 6 and tumor necrosis factor α, on cognitive outcomes following ECT. Given these results, further exploration of the potential roles of immunomodulatory effects on ECT treatment outcomes, as well as adverse cognitive side effects, is indicated.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"232-239"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcranial Random Noise Stimulation in the Management of Cognitive and Behavioral Symptoms in a Suicidal Hanging Survivor: A Case Study. 经颅随机噪声刺激治疗一名有上吊自杀倾向的幸存者的认知和行为症状：案例研究。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-01 Epub Date: 2024-03-21 DOI: 10.1097/YCT.0000000000001011

Sujita Kumar Kar, Rahul Prajapati, Vikas Bharti, Sanjana Bhasin, Priyanshi Chaudhary, Devika Raje

引用次数: 0