Journal of Ect最新文献

{"title":"Resolution of Postictal Catatonia With Electroconvulsive Therapy in Temporal Lobe Epilepsy: A Rare Case Report.","authors":"Swapnajeet Sahoo, Rajlaxmi, Sahil Mehta, Mritunjay Khandelwal, Subho Chakrabarti, Sandeep Grover","doi":"10.1097/YCT.0000000000001197","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001197","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":"42 2","pages":"e26-e27"},"PeriodicalIF":1.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Dose Flumazenil and Caffeine to Facilitate Electroconvulsive Therapy in Malignant Catatonia.","authors":"Mark Volpe, Dallas Hamlin, Emma Batchelder, Charles Mormando, Andrew Francis","doi":"10.1097/YCT.0000000000001165","DOIUrl":"10.1097/YCT.0000000000001165","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e17-e18"},"PeriodicalIF":1.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report on the Role of Continuous Theta Burst Stimulation in Managing Dystonia in a Patient With Wilson's Disease.","authors":"Ankita Saroj, Sandhya Verma, Mohita Joshi, Praveen Kumar Sharma, Sujita Kumar Kar","doi":"10.1097/YCT.0000000000001186","DOIUrl":"10.1097/YCT.0000000000001186","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e18-e19"},"PeriodicalIF":1.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-Term and Long-Term Outcomes of Electroconvulsive Therapy in Patients With Impaired Decision-Making Capacity.","authors":"Norihiko Umetani, Fuminari Misawa, Hiroyoshi Takeuchi","doi":"10.1097/YCT.0000000000001282","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001282","url":null,"abstract":"<p><strong>Objective: </strong>Evidence about nonvoluntary electroconvulsive therapy (ECT) is limited. Observational studies have suggested that nonvoluntary ECT is equally effective as voluntary ECT in treating psychotic and mood disorders. However, prior studies with short follow-up periods of ∼6 months have been inconclusive regarding long-term clinical outcomes following nonvoluntary ECT, particularly in patients with schizophrenia-spectrum disorders.</p><p><strong>Methods: </strong>We conducted a retrospective chart review and included patients who received ECT treatment between 2016 and 2023 at our hospital. The patients were assigned to the nonvoluntary and voluntary groups. We compared the short-term and long-term outcomes between the 2 groups over a 1-year period.</p><p><strong>Results: </strong>In total, 227 patients were included in this study: 58 in the nonvoluntary group and 169 in the voluntary group. No significant intergroup differences were observed in short-term outcomes, such as the clinical global impressions-improvement scale score, number of discharged patients, and duration of admission. Furthermore, the Cox proportional hazard model found that the nonvoluntary group was not significantly associated with treatment failure 1 year after discharge (hazard ratio: 0.94, 95% CI: 0.55-1.61). However, 6 patients in the nonvoluntary ECT group underwent the procedure again, representing a statistically significant difference.</p><p><strong>Conclusions: </strong>Nonvoluntary ECT may be an effective treatment option for patients with life-threatening conditions when no alternative is available. However, further investigation is needed to explore ways to improve patient acceptance of future treatments.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-Resistant Psychosis in a Tuberous Sclerosis Patient Treated With Electroconvulsive Therapy.","authors":"Hasan B Kayaci, Lala Allahyarova, Nevzat Tarhan, Bariş Metin","doi":"10.1097/YCT.0000000000001285","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001285","url":null,"abstract":"<p><p>Tuberous sclerosis complex (TSC) leads to the development of severe neuropsychiatric disorders (TAND), which do not respond to treatment (1). This paper focuses on a 17-year-old male with TSC and uncontrolled epilepsy, which started when he was 1 year old. The surgical removal of his left frontal tuber successfully stopped his seizures (2). Afterwards, his psychiatric condition deteriorated into a treatment-resistant psychosis, which caused him to experience severe agitation and hallucinations. This inverse pattern-gaining seizure control but losing psychiatric stability led us to question whether forced normalization might be the underlying cause. (3,4). Electroconvulsive therapy (ECT) was chosen because pharmacotherapy did not produce a satisfactory response. This decision was made even though the patient had multiple risk factors, including a large postsurgical cortical defect, remaining cortical tubers, and a previous history of status epilepticus (5,6). He received 12 inpatient ECT sessions (10 unilateral, 2 bilateral) and 6 outpatient sessions (18 total), and his post-ECT maintenance was gradually tapered from every 2 weeks to once every 2 months, which successfully eliminated his psychotic symptoms. He experienced no neurological complications. This treatment experience demonstrates that ECT provides a safe method to treat severe TAND psychosis or Force Normalization (FN) psychosis, which does not respond to other treatments, even for patients who have brain structure changes following neurosurgical procedures (4,5).</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroconvulsive Therapy Induced Neurogenic Pulmonary Edema in a Survivor of Carbon Monoxide Poisoning: A Case Report.","authors":"Annie Janus, Milankumar Nathani, Cheri Sulek, Nicholas Mudra, Dawn Bruijnzeel, Srinath Gopinath","doi":"10.1097/YCT.0000000000001280","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001280","url":null,"abstract":"<p><p>Neurogenic pulmonary edema (NPE) is a life-threatening complication of severe central nervous system (CNS) injury. Carbon monoxide (CO) poisoning causes significant CNS insults, including direct neurotoxicity and autonomic dysfunction, creating a high-risk neurological state. Electroconvulsive therapy (ECT), while an effective treatment for severe depression, induces profound physiological stress that can exacerbate underlying neuropathology, thereby increasing the risk of NPE. We present the case of a 62-year-old male with severe depression who was hospitalized after a suicide attempt through CO poisoning, who developed NPE after undergoing his first ECT session. Shortly after the first ECT treatment, the patient became hypertensive, agitated and developed respiratory distress. NPE was diagnosed based on clinical findings and radiographic evidence of prominent pulmonary vasculature. Despite medical management, the patient required emergent intubation and intensive care unit (ICU) management. The patient's condition improved with supportive care, and he was successfully extubated the following day. ECT was discontinued. This case highlights a rare but severe complication of ECT in a patient with pre-existing CNS vulnerability from CO poisoning. The physiological stress from ECT likely precipitated the sympathetic surge leading to NPE. This report underscores the potential dangers of performing ECT after recent CO poisoning and, when considered with the related research discussed herein, suggests that recent CO poisoning should be considered a relative contraindication for ECT. Clinicians must be vigilant about this complication and be prepared for its management.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postictal EEG Suppression and Peripheral Inflammatory Markers During Electroconvulsive Therapy: Evidence From Schizoaffective Disorder.","authors":"Kader S Karatas, Yasemin Solmaz, Onur Gokcen, Merve Akkus, Feyza Donmez","doi":"10.1097/YCT.0000000000001284","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001284","url":null,"abstract":"<p><strong>Introduction: </strong>Postictal EEG suppression is considered a key indicator of seizure quality during electroconvulsive therapy (ECT); however, its biological correlates remain incompletely understood. Emerging evidence suggests that systemic inflammatory activity may influence cortical recovery following induced seizures. Whether this neuroimmune interaction differs across psychiatric diagnoses has not been systematically examined.</p><p><strong>Methods: </strong>This retrospective cross-sectional study analyzed EEG parameters recorded during ECT together with peripheral inflammatory markers in 60 patients undergoing ECT. The primary focus was schizoaffective disorder, with bipolar disorder and other diagnoses examined for comparison. EEG indices included tonic and clonic phase durations and postictal suppression. Inflammatory measures comprised C-reactive protein (CRP), neutrophil counts, hemoglobin levels, and composite indices such as the Inflammatory Burden Index (IBI). Associations were evaluated using Spearman correlation analyses with correction for multiple comparisons.</p><p><strong>Results: </strong>In the schizoaffective disorder subgroup, postictal duration showed strong and biologically coherent associations with inflammatory markers, including a significant inverse correlation with neutrophil count that remained robust after false discovery rate correction. Additional associations with hemoglobin levels and IBI were observed. In contrast, bipolar disorder demonstrated only a limited association between postictal duration and CRP, while other EEG-inflammatory relationships were weak or nonsignificant.</p><p><strong>Discussion: </strong>Postictal EEG suppression appears to reflect diagnosis-specific neuroimmune modulation during ECT, with schizoaffective disorder showing particularly pronounced coupling between cortical recovery and systemic inflammatory activity. Postictal EEG features may therefore represent biologically meaningful markers beyond conventional measures of seizure adequacy and contribute to a more mechanistic understanding of ECT response.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroconvulsive Therapy for the Neuropsychiatric Manifestations of Amyostatic-Akinetic Encephalitis Lethargica: A Case Report.","authors":"Nicholas Bonomo, Aditya Shah, Yuyao Ding, Anna Foster, Rif S El-Mallakh, George Kalayil","doi":"10.1097/YCT.0000000000001278","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001278","url":null,"abstract":"<p><p>Encephalitis lethargica, first described in 1917 as a sequela of the Spanish flu, was characterized by a nonspecific inflammatory prodrome followed by profound sleep disturbances and chronic neurological sequelae, particularly postencephalitic Parkinsonism. Though numerous theories have been suggested to explain encephalitis lethargica, the rarity of the condition has limited formal investigations. Described here may be the first case of encephalitis lethargica in which the neuropsychiatric symptoms were successfully treated with electroconvulsive therapy. A middle-aged male, who initially presented with heterophonic palilalia following a protracted hospitalization for COVID-19 encephalitis 3 months prior, was admitted to inpatient psychiatry for a recurrence of palilalia. He rapidly deteriorated, developing extraocular ophthalmoplegia, persistent insomnia, severe intermittent tachypnea, acute Parkinsonism, and eventual akinetic mutism. He met the criteria described by Howard and Lee for encephalitis lethargica, with a presentation most consistent with the amyostatic-akinetic subtype. He failed pharmacological management but showed a marked improvement following 4 treatments with ultrabrief pulse right unilateral electroconvulsive therapy. Since discharge, his symptomatology has been controlled with 2 years of maintenance treatment.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroconvulsive Therapy for Catatonia in Lewy Body Dementia: A Case Report Highlighting Legal Delays in Care.","authors":"Sebastian Andrade, Fawwad Khan, Joseph J Cooper","doi":"10.1097/YCT.0000000000001274","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001274","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduction of CACNA1D-Associated Catatonia Symptoms in an Adolescent With Concurrent Severe Autism Spectrum Disorder: A Case Report.","authors":"Ryley Mancine, Joanna Kuang, Christina Raghunandan, Alexander Palffy","doi":"10.1097/YCT.0000000000001279","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001279","url":null,"abstract":"<p><p>Autism spectrum disorder (ASD) may be a predisposing factor in the development of catatonia, which has been demonstrated to be effectively treated using electroconvulsive therapy (ECT). CACNA1 channelopathy mutations have been associated with autism spectrum disorder, intellectual disability, and epilepsy. The single published case report of ECT use in CACNA1 subunit mutations demonstrated a negative outcome, and no current case reports on CACNA1B, CACNA1C, CACNA1D, or CACNA1E mutations have been published. We present a case of an adolescent with a known CACNA1D mutation and symptoms of excited catatonia who experienced a reduction in the frequency and severity of self-injurious and violent behavior following treatment with ECT. Our case demonstrates the use of ECT for catatonia in an individual with a CACNA1 mutation without complication and with a positive therapeutic response.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}