Journal of EctPub Date : 2024-06-01DOI: 10.1097/YCT.0000000000001030
Randall T Espinoza
{"title":"Editors Roundup: Words Do Matter, How Do We Teach About ECT and What Does YouTube Have to Show, and ECT Practice Around the World.","authors":"Randall T Espinoza","doi":"10.1097/YCT.0000000000001030","DOIUrl":"10.1097/YCT.0000000000001030","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":"40 2","pages":"65-66"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of EctPub Date : 2024-06-01Epub Date: 2023-11-29DOI: 10.1097/YCT.0000000000000971
Pontus Strandberg, Axel Nordenskjöld, Robert Bodén, Carl Johan Ekman, Johan Lundberg, Katarzyna Popiolek
{"title":"Electroconvulsive Therapy Versus Repetitive Transcranial Magnetic Stimulation in Patients With a Depressive Episode: A Register-Based Study.","authors":"Pontus Strandberg, Axel Nordenskjöld, Robert Bodén, Carl Johan Ekman, Johan Lundberg, Katarzyna Popiolek","doi":"10.1097/YCT.0000000000000971","DOIUrl":"10.1097/YCT.0000000000000971","url":null,"abstract":"<p><strong>Objectives: </strong>Electroconvulsive therapy (ECT) and repetitive transcranial magnetic stimulation (rTMS) are both effective in treating depression. Although rTMS induces fewer adverse effects, its effectiveness relative to ECT is not well established. The aim of this study was to investigate the treatment outcomes of ECT and rTMS in patients who have received both interventions.</p><p><strong>Methods: </strong>This was a register-based observational crossover study in patients with depression who had undergone ECT and rTMS in Sweden between 2012 and 2021. Primary outcome was reduction in the Montgomery-Åsberg Depression Rating Scale-Self-report (MADRS-S) score. Secondary outcome was response defined as a 50% or greater decrease in the MADRS-S score. Subgroup analyses were performed to identify factors that predicted differential responses between rTMS and ECT. Continuous and categorical variables were analyzed using paired-samples t tests and McNemar tests, respectively.</p><p><strong>Results: </strong>In total, 138 patients across 19 hospitals were included. The MADRS-S score after ECT and rTMS was reduced by 15.0 and 5.6 ( P = 0.0001) points, respectively. Response rates to ECT and rTMS were 38% and 15% ( P = 0.0001), respectively. Electroconvulsive therapy was superior across all subgroups classified according to age and severity of depression.</p><p><strong>Conclusions: </strong>Our results suggest that ECT is more effective than rTMS in treating depression among patients who have received both interventions. Age and baseline depression severity did not predict who would similarly benefit from rTMS and ECT.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"88-95"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138479375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of EctPub Date : 2024-06-01DOI: 10.1097/YCT.0000000000001022
William V McCall
{"title":"Electroconvulsive Therapy Does Not Cause \"Brain Damage\".","authors":"William V McCall","doi":"10.1097/YCT.0000000000001022","DOIUrl":"10.1097/YCT.0000000000001022","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":"40 2","pages":"67-68"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of EctPub Date : 2024-06-01Epub Date: 2023-12-07DOI: 10.1097/YCT.0000000000000976
Thomas Diot, Stéphane Mouchabac, Philippe Giraud, Florian Ferreri, Vladimir Adrien
{"title":"Electroconvulsive Therapy for Major Depressive Disorder Induced by Androgen Deprivation Therapy: Report of 2 Cases.","authors":"Thomas Diot, Stéphane Mouchabac, Philippe Giraud, Florian Ferreri, Vladimir Adrien","doi":"10.1097/YCT.0000000000000976","DOIUrl":"10.1097/YCT.0000000000000976","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e7-e8"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138813212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Safe and Successful Electroconvulsive Therapy After an Ascending Aorta Replacement: A Case Report.","authors":"Yoshio Ohya, Shinji Sakamoto, Yuto Yamada, Shintaro Takenoshita, Yuji Higuchi, Norihito Yamada, Manabu Takaki","doi":"10.1097/YCT.0000000000000973","DOIUrl":"10.1097/YCT.0000000000000973","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":"40 2","pages":"e6-e7"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of EctPub Date : 2024-06-01Epub Date: 2024-05-20DOI: 10.1097/YCT.0000000000001019
Conrad M Swartz
{"title":"What Is Brain Damage and Does Electroconvulsive Therapy Cause It?","authors":"Conrad M Swartz","doi":"10.1097/YCT.0000000000001019","DOIUrl":"10.1097/YCT.0000000000001019","url":null,"abstract":"<p><strong>Abstract: </strong>Surveys show public misperceptions and confusion about brain damage and electroconvulsive therapy (ECT). Fictional movies have misrepresented ECT to suggest brain damage and to ridicule mental illness and psychiatric patients. \"Brain damage\" has become a colloquial expression without consistent meaning. In contrast, brain injury is the medical term for destruction of brain cells, such as from kinetic impact (concussion), hypoxia, or infection. Studies of both high-resolution magnetic resonance imaging (MRI) and enzyme assays find that causes of brain injury are accompanied by observable structural changes on MRI and elevated blood and cerebrospinal fluid levels of brain enzymes that leak from injured brain cells. Concussion is also followed by intracerebral bleeding, progressive brain atrophy, diffuse axonal injury, cranial nerve injury, and 2-4 fold increased risk for dementia. In contrast, there is no evidence that ECT produces any of these. Studies of ECT patients find no brain edema, structural change persisting 6 months, or elevated levels of leaked brain enzymes. Statistical comparisons between brain injury and ECT effects indicate no similarity ( P < 0.00000001). Moreover, the kinetic, thermal, and electrical effects of ECT are far below levels that could possibly cause harm. This robust evidence shows that there is no basis to claim that ECT causes brain injury.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"72-77"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141071177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of EctPub Date : 2024-06-01Epub Date: 2024-01-09DOI: 10.1097/YCT.0000000000000984
Mette Krarup, Charles H Kellner, Søren D Østergaard
{"title":"Clinical and Legal Differences in the Use of Involuntary Electroconvulsive Therapy for Life-Threatening Illness Across European Countries.","authors":"Mette Krarup, Charles H Kellner, Søren D Østergaard","doi":"10.1097/YCT.0000000000000984","DOIUrl":"10.1097/YCT.0000000000000984","url":null,"abstract":"<p><strong>Objectives: </strong>Electroconvulsive therapy (ECT) can be life-saving in situations where patients are at risk of dying from severe manifestations of psychiatric illness. In some of these cases, patients are unwilling/unable to consent to ECT, and involuntary ECT is required. Such use of involuntary ECT varies substantially across European countries for unclear reasons. The aim of this study was to examine clinical and legal differences in this use of involuntary ECT across European countries.</p><p><strong>Methods: </strong>A questionnaire based on a case vignette (a 55-year-old female inpatient with psychotic depression at imminent risk of dying from metabolic derangement because of refusal to eat and drink) was sent to an ECT practitioner in each of 31 European countries.</p><p><strong>Results: </strong>We received responses from ECT practitioners in 18 countries. In 7 of these countries, involuntary ECT could be carried out without approval from others and/or involvement of the court system in the case described in the vignette. Practitioners in the remaining 11 countries responded that they either could not carry out involuntary ECT or would have to meet certain requirements before initiating involuntary ECT (e.g., approval from medical/ethics committee and second opinion from an independent psychiatrist). Notably, the rules regarding involuntary ECT differed for adults and minors (more restrictive for the latter) in 6 of the 18 countries.</p><p><strong>Conclusions: </strong>In many European countries, legislation precludes or delays the use of involuntary ECT. Harmonization of the legislation on involuntary ECT across European countries to allow for better access to this potentially life-saving treatment seems warranted.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"105-110"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Therapeutic Role of Intermittent Theta Burst Stimulation in Schizophrenia: A Systematic Review and Meta-analysis.","authors":"Dorsa Salabat, Amirali Pourebrahimi, Mahsa Mayeli, Giulia Cattarinussi","doi":"10.1097/YCT.0000000000000972","DOIUrl":"10.1097/YCT.0000000000000972","url":null,"abstract":"<p><strong>Abstract: </strong>Schizophrenia affects approximately 1% of the population worldwide. Multifactorial reasons, ranging from drug resistance to adverse effects of medications, have necessitated exploring further therapeutic options. Intermittent theta burst stimulation (iTBS) is a novel high-frequency form of transcranial magnetic stimulation, a safe procedure with minor adverse effects with faster and longer-lasting poststimulation effects with a potential role in treating symptoms; however, the exact target brain regions and symptoms are still controversial. Therefore, we aimed to systematically investigate the current literature regarding the therapeutic utilities of iTBS using Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Twelve studies were included among which 9 found iTBS effective to some degree. These studies targeted the dorsolateral prefrontal cortex and the midline cerebellum. We performed a random-effects meta-analysis on studies that compared the effects of iTBS on schizophrenia symptoms measured by the Positive and Negative Syndrome Scale (PANSS) to sham treatment. Our results showed no significant difference between iTBS and sham in PANSS positive and negative scores, but a trend-level difference in PANSS general scores ( k = 6, P = 0.07), and a significant difference in PANSS total scores ( k = 6, P = 0.03). Analysis of the studies targeting the dorsolateral prefrontal cortex showed improvement in PANSS negative scores ( k = 5, standardized mean difference = -0.83, P = 0.049), but not in PANSS positive scores. Moderators (intensity, pulse, quality, sessions) did not affect the results. However, considering the small number of studies included in this meta-analysis, future works are required to further explore the effects of these factors and also find optimum target regions for positive symptoms.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"78-87"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139567575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of EctPub Date : 2024-06-01Epub Date: 2024-02-09DOI: 10.1097/YCT.0000000000000975
Joshua Berman
{"title":"Teaching ECT to Medical Students: Literature Review, Commentary, and a Suggested Change in Perspective.","authors":"Joshua Berman","doi":"10.1097/YCT.0000000000000975","DOIUrl":"10.1097/YCT.0000000000000975","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"69-71"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139906940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of EctPub Date : 2024-06-01Epub Date: 2024-02-24DOI: 10.1097/YCT.0000000000001005
Katarzyna Popiolek, Tor Arnison, Robert Boden, Carl Johan Ekman, Johan Lundberg, Pontus Strandberg, Axel Nordenskjöld
{"title":"Electroconvulsive Therapy Versus Repetitive Transcranial Magnetic Stimulation in Patients With a Depressive Episode: A Register-Based Study.","authors":"Katarzyna Popiolek, Tor Arnison, Robert Boden, Carl Johan Ekman, Johan Lundberg, Pontus Strandberg, Axel Nordenskjöld","doi":"10.1097/YCT.0000000000001005","DOIUrl":"10.1097/YCT.0000000000001005","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"140-141"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}