Journal of Ect最新文献

{"title":"Theta Burst Stimulation With Facial Titanium Implants: A Case Report and Review of Literature.","authors":"Imamulhaq Brula, Elizabeth Mayfield Arnold, Gopalkumar Rakesh","doi":"10.1097/YCT.0000000000001195","DOIUrl":"10.1097/YCT.0000000000001195","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e21-e22"},"PeriodicalIF":1.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145454024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Refractory Pediatric Catatonia in the Setting of Neurodegenerative Illness: Safe and Effective Use of Electroconvulsive Therapy.","authors":"Molly Olmstead, Amelia Denney, Matthew Kark, Roslyn Gerwin, Avital Fischer","doi":"10.1097/YCT.0000000000001202","DOIUrl":"10.1097/YCT.0000000000001202","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e22-e23"},"PeriodicalIF":1.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Effects of Dexmedetomidine and Remifentanil on Seizure Duration, Hemodynamics, and Recovery Time in Electroconvulsive Therapy.","authors":"Irem Durmus, Ozlem Sezen, Banu Cevik, Merih Altintas","doi":"10.1097/YCT.0000000000001161","DOIUrl":"10.1097/YCT.0000000000001161","url":null,"abstract":"<p><strong>Objectives: </strong>Electroconvulsive therapy (ECT) is an important treatment method that is widely used in psychiatric conditions resistant to pharmacological treatments.</p><p><strong>Methods: </strong>This prospective, randomized study included 100 patients undergoing ECT. Group D received dexmedetomidine and propofol, while group R received remifentanil and propofol. In this study, key parameters such as seizure duration, hemodynamic changes, and recovery time were analyzed.</p><p><strong>Results: </strong>The investigation revealed no statistically significant differences between the groups with regard to mean age, gender distribution, or seizure duration ( P  > 0.05). Subsequent to induction, group R exhibited statistically significantly lower systolic blood pressure, diastolic blood pressure, and mean arterial pressures in comparison to group D ( P  < 0.05). Conversely, heart rate, systolic blood pressure, diastolic blood pressure, and mean arterial pressure levels in group R were found to be statistically significantly higher than in group D ( P  < 0.05). The recovery time in group D was found to be statistically significantly longer than in group R ( P  < 0.05).</p><p><strong>Conclusions: </strong>Dexmedetomidine provides superior hemodynamic stability, while remifentanil ensures faster recovery. Dexmedetomidine has been shown to be more advantageous in terms of hemodynamic stability, while remifentanil has been demonstrated to result in shorter recovery times. Clinicians should tailor anesthetic choices based on patient profiles and therapeutic goals.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"119-124"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse Effects and Efficacy of Bifrontal Electroconvulsive Therapy: Insights From a Retrospective Study at a Leading Mental Health Institution in Türkiye.","authors":"Ceyhan Oflezer, Hasan Gökçay, Zümrüt Ela Kaşdoğan, Özge Atay, Yusuf B Sikar, Melih Avci","doi":"10.1097/YCT.0000000000001192","DOIUrl":"10.1097/YCT.0000000000001192","url":null,"abstract":"<p><strong>Background: </strong>This study aims to evaluate the safety and efficacy of bifrontal electroconvulsive therapy (ECT) in managing psychiatric disorders, focusing on the occurrence and progression of adverse effects across treatment sessions.</p><p><strong>Methods: </strong>A retrospective review was conducted using medical records of 2130 patients who underwent ECT between 2019 and 2023 at a major psychiatric center in Türkiye. Sociodemographic characteristics, clinical data, and treatment-related adverse events were analyzed. Bifrontal ECT was administered according to standardized protocols, with continuous monitoring of vital signs and adverse effects.</p><p><strong>Results: </strong>The majority of patients (86%) underwent ECT due to failure of pharmacotherapy. The mean age of the cases was 30.95±10.15 years, with schizophrenia (30.7%) and bipolar mania (26.9%) being the most common diagnoses. Adverse event rates decreased from 13.7% in the first session to 1.2% in the tenth. Prolonged seizures (9.1% in session 1, 0.8% by session 10) and mild cognitive effects, such as confusion (0.2% to 0.4%), were observed but were managed effectively. Rare complications included hypersalivation (0.2% to 1.3%) and dental trauma (0.1%). No severe or life-threatening events were reported. Overall, bifrontal ECT achieved full remission in 57.6% and partial remission in 28.9% of patients.</p><p><strong>Conclusions: </strong>Bifrontal ECT demonstrates a favorable safety profile and clinical efficacy, particularly in cases unresponsive to pharmacological treatments. The low rates of cognitive and physiological adverse effects underscore its utility as a balanced therapeutic approach. Future studies are warranted to expand on these findings and refine treatment protocols.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"128-135"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147596336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI-Guided rTMS Targeting the Dorsolateral Prefrontal Cortex Improves Negative Symptoms and Cognitive Function in Schizophrenia: Evidence From a Randomized Controlled Trial.","authors":"Yujuan Guo, Chengrui Jin, Xiaomin Chen, Likun Qin","doi":"10.1097/YCT.0000000000001287","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001287","url":null,"abstract":"<p><strong>Background: </strong>Negative symptoms of schizophrenia respond poorly to medication. rTMS targeting the dorsolateral prefrontal cortex (DLPFC) is promising but variably effective, partly due to targeting inaccuracy. In this study, we evaluated the efficacy and safety of MRI-guided rTMS for negative symptoms of schizophrenia.</p><p><strong>Methods: </strong>In this single-center, randomized, assessor-blinded, sham-controlled trial, 100 patients were assigned 1:1 to MRI-guided neuronavigated active rTMS or sham for 4 weeks (20 sessions). Individualized left DLPFC targets were defined on structural MRI. The primary outcome was the change in PANSS negative factor score at week 4. Secondary outcomes were SANS, MoCA, and PSP. Adverse events were recorded. Repeated-measures ANOVA was used for primary and secondary clinical outcomes, and exploratory correlation analyses were performed for stimulation deviation measures.</p><p><strong>Results: </strong>Active rTMS reduced negative symptoms more than sham (ΔPANSS-N: -6.5±3.0 vs. -2.7±2.9; P<0.001), with a significant time×group interaction (P=0.001). MoCA and PSP improved versus sham (P=0.01; P=0.005). Treatment was well tolerated with mild, transient adverse events. Exploratory analyses showed that smaller stimulation-to-target deviations were associated with greater PANSS improvement (r=-0.42, P=0.002), and symptom reduction correlated with cognitive gains (r=0.41, P=0.003).</p><p><strong>Conclusions: </strong>Active MRI-guided rTMS was more effective than sham stimulation in reducing negative symptoms in patients with schizophrenia over 4 weeks and was well tolerated. Secondary improvements in cognitive and functional measures were observed, but these findings should be interpreted as supportive outcomes. Exploratory analyses related to stimulation deviation were hypothesis-generating only. However, because depressive symptoms were not systematically assessed in this trial, it cannot be excluded that part of the observed improvement in negative symptoms may reflect changes in depressive symptomatology.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148145465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Magnetic Seizure Therapy Effective in Treating Anhedonia Symptoms in Treatment-Resistant Depression? Preliminary Evidence from a Case Series.","authors":"Vitor Breseghllo Cavenaghi, Adriana Munhoz Carneiro, Helena Belini, Eric Cretaz, Leonardo Afonso Dos Santos, André Russowsky Brunoni","doi":"10.1097/YCT.0000000000001213","DOIUrl":"10.1097/YCT.0000000000001213","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e27-e28"},"PeriodicalIF":1.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145716178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dopamine Supersensitivity Psychosis Successfully Treated With Combination Therapy of Modified Electroconvulsive Therapy and Long-Acting Injectable in the Acute Phase: A Case Report.","authors":"Kouhei Sato, Koji Otsuki, Michiharu Nagahama, Masatoshi Inagaki","doi":"10.1097/YCT.0000000000001203","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001203","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":"42 2","pages":"e23-e25"},"PeriodicalIF":1.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148036813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"His Discovery Has Revolutionized Psychiatry; It Has Opened Vast Horizons\": Ugo Cerletti, a Missing Nobel Prize Laureate?","authors":"Elisabetta Sirgiovanni, Nils Hansson","doi":"10.1097/YCT.0000000000001136","DOIUrl":"10.1097/YCT.0000000000001136","url":null,"abstract":"<p><strong>Abstract: </strong>Drawing on original sources from Italian and Swedish archives, this article provides novel insights into the life of Ugo Cerletti (1877-1963). Cerletti, the Italian neuropsychiatrist and originator (with his assistant Lucio Bini) of electroconvulsive therapy (ECT) in the late 1930s, strongly coveted the Nobel Prize in the 1950s and 1960s. He would never receive it, despite maintaining close correspondence with his nominators and informants in Sweden. This article critically discusses potential reasons for the rejection of his candidacy, including the tensions between Cerletti and Bini and the general climate of suspicion against ECT that began in the 1960s, and draws comparisons with other missing Nobel laureates. The research herein adds previously unknown details to the history of ECT; it will be shown that Cerletti was opposed by some members of the Nobel committee even before popular anti-ECT attacks and that his attempts to remedy this situation were unsuccessful.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"73-79"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relative Efficacy and Side-Effect Profile of Ultrabrief Pulse and Brief Pulse ECT: A Systematic Review of Recent Literature.","authors":"Rishi Gonuguntla, Sam Dunham, Isaac Benmaman, Neha Gonuguntla, Kevin Ha","doi":"10.1097/YCT.0000000000001164","DOIUrl":"10.1097/YCT.0000000000001164","url":null,"abstract":"<p><strong>Objective: </strong>Electroconvulsive therapy (ECT) is an interventional psychiatric technique used primarily to address treatment resistant psychiatric disorders. There are many different stimulus electrode placements and pulse widths utilized in the administration of this therapy, but it is presently unclear which is optimal. The aim of this study is to assess the relative efficacy and side-effect profile of ultrabrief pulse width ECT (UBP ECT) and brief-pulse width ECT (BP ECT) in the treatment of major depressive disorders.</p><p><strong>Method: </strong>A systematic review of the literature was performed. Studies were identified from PubMed, MEDLINE and PsycINFO between January 2013 to October 2023. The final search terms included ECT, depression, brief pulse, and ultrabrief pulse.</p><p><strong>Results: </strong>The search initially included 64 studies. Forty-three of these studies were not duplicates, after applying exclusion criteria 11 studies were included. UBP ECT was found to have fewer cognitive side effects than BP ECT. Additionally, patients undergoing BP ECT were found to discontinue treatment more frequently due to inability to tolerate side effects. Despite this, BP ECT may have higher rates of symptom remission than UBP ECT. Further studies should be done to clarify the outcomes of each technique.</p><p><strong>Conclusions: </strong>The current evidence slightly favors UBP ECT due to its beneficial side effect profile compared to BP ECT while it has a similar efficacy. However, there is insubstantial evidence in the current body of literature. Additional studies are required to determine which of these techniques is safer and more efficacious in the treatment of major depressive disorders.</p><p><strong>Study design: </strong>Systematic review.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"80-85"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Electroconvulsive Therapy in Postpartum Psychosis: A Systematic Review.","authors":"Orlando Herrera-Barrón, Ximena Cors-Cepeda, Cynthia López-García, Jesus Paez-Mayorga, Angélica Baca-De-Anda","doi":"10.1097/YCT.0000000000001188","DOIUrl":"10.1097/YCT.0000000000001188","url":null,"abstract":"<p><p>Postpartum psychosis is a severe psychiatric condition that emerges shortly after childbirth. Electroconvulsive therapy provides rapid symptom relief, particularly in severe and treatment-resistant cases. Despite evidence supporting its effectiveness, the use of electroconvulsive therapy in postpartum psychosis remains limited and unstandardized. This systematic review evaluates the clinical effectiveness of electroconvulsive therapy in treating postpartum psychosis. A comprehensive search of PubMed/MEDLINE, Cochrane, SciELO, SCOPUS, and Web of Science identified 255 studies, of which 7 met the inclusion criteria. Electroconvulsive therapy was used exclusively in severe cases that did not respond to pharmacological treatment, leading to symptom improvement in all cases, with most achieving complete remission. The total number of electroconvulsive therapy sessions ranged from 5 to 15, with symptom improvement observed after 1 to 6 sessions and remission after 5 to 11 sessions. Reported side effects, including memory loss, mild cognitive deficits, and pain, were transient. These findings highlight the effectiveness of electroconvulsive therapy as a rapid and safe intervention for postpartum psychosis, particularly when pharmacological treatments are insufficient. However, small sample sizes and variability in treatment protocols limit the generalizability of results. Further prospective studies are needed to establish standardized guidelines and consider electroconvulsive therapy as a first-line treatment for postpartum psychosis.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":"42 2","pages":"86-95"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}