Journal of Ect最新文献_第7页

Acceptability, Feasibility, and Effectiveness of Concurrent High-Definition Transcranial Direct Current Stimulation and Cue Exposure in Cannabis Use Disorder: A Pilot Double-Blind Randomized Controlled Trial. 同时高清晰度经颅直流电刺激和线索暴露治疗大麻使用障碍的可接受性、可行性和有效性：一项先导双盲随机对照试验。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-24 DOI: 10.1097/YCT.0000000000001087

Devika Chauhan, Abhishek Ghosh, Shalini S Naik, Devender K Rana, Shubh Mohan Singh

{"title":"Acceptability, Feasibility, and Effectiveness of Concurrent High-Definition Transcranial Direct Current Stimulation and Cue Exposure in Cannabis Use Disorder: A Pilot Double-Blind Randomized Controlled Trial.","authors":"Devika Chauhan, Abhishek Ghosh, Shalini S Naik, Devender K Rana, Shubh Mohan Singh","doi":"10.1097/YCT.0000000000001087","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001087","url":null,"abstract":"Objectives: We studied the acceptability, feasibility, tolerability, and preliminary effectiveness of combined cue exposure and anodal high-definition transcranial direct current stimulation (HD-tDCS) on the right dorsolateral prefrontal cortex (DLPFC) on cannabis craving in cannabis use disorder (CUD).Methods: We randomly assigned 48 participants equally in 4 groups: A, tDCS and cannabis cue exposure; B, tDCS and neutral image; C, sham tDCS and cue exposure; and D, sham tDCS and neutral image. The images were validated by Delphi consensus. All participants received 6 sessions. We explored the acceptance, protocol completion, and follow-up rates. We assessed cannabis cravings twice, at the end of sessions and 4 weeks after intervention; change in frequency and amount of cannabis and other substance use were assessed at 4 weeks after intervention; working memory and executive functions were tested at the end of sessions. We performed an intention-to-treat analysis.Results: We observed low acceptance (19.6%) but high completion (91.7%) and follow-up rates. There were motivational and logistical reasons for low acceptance; monetary compensation improved treatment acceptance. Participants in all groups showed significant reductions in cannabis cravings at the end of sessions, except for group C, the reduction in cravings sustained at the follow-up. Frequency and amount of cannabis use reduced, and cognitive outcomes improved in all 4 groups; however, there was no between-group difference, and changes were higher in groups B and D. Adverse effects and attrition were not different between HD-tDCS and sham treatment.Conclusions: Anodal right DLPFC HD-tDCS is a safe and promising treatment for CUD. Cue exposure does not add to its effect.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Cholinesterase Inhibitors for Treatment and Prevention of Cognitive Adverse Effects of Electroconvulsive Therapy: A Systematic Review. 使用胆碱酯酶抑制剂治疗和预防电休克治疗的认知不良反应：一项系统综述。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-17 DOI: 10.1097/YCT.0000000000001095

Angela Dylewski, Amanda C Holder, Jamie N Brown

{"title":"Use of Cholinesterase Inhibitors for Treatment and Prevention of Cognitive Adverse Effects of Electroconvulsive Therapy: A Systematic Review.","authors":"Angela Dylewski, Amanda C Holder, Jamie N Brown","doi":"10.1097/YCT.0000000000001095","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001095","url":null,"abstract":"Abstract: Although electroconvulsive therapy (ECT) is effective for treating depression, schizophrenia, and mania, cognitive adverse effects may limit use. One possible mechanism for these effects includes cholinergic transmission alterations, supporting potential use of cholinesterase inhibitors for prevention and treatment of these cognitive deficits. The objective of this review is to determine efficacy and safety of cholinesterase inhibitors clinically used for dementia in reducing ECT cognitive adverse effects. PubMed, EMBASE, and CENTRAL were searched in August 2024 for randomized controlled trials using terms and keywords related to cholinesterase inhibitors (acetylcholinesterase inhibitor, cholinesterase inhibitor, donepezil, galantamine, or rivastigmine) and ECT (electroconvulsive therapy, electroconvulsive, electroshock therapy, or ECT). A total of 8 randomized controlled trials were reviewed with mean patient ages ranging from 28.6 to 59.33 years and most common diagnoses including depressive disorders, schizophrenia/psychosis, and bipolar disorder. Six of the 8 trials showed benefits of using cholinesterase inhibitors in patients undergoing ECT. Significant improvements were found in immediate memory after ECT and recovery of personal memory, repetition, alertness, orientation, and impersonal memory compared with placebo. Trials varied in cognitive assessment scales, length of therapy, dosing strategy, ECT schedule, and ECT type/parameters. Cholinesterase inhibitors may be effective for reducing cognitive adverse effects of ECT and appear safe and well tolerated. The most commonly studied medication was donepezil 5 mg daily started shortly before and continued throughout ECT. Additional studies are needed to clarify optimal dosing, titration, duration of therapy, and the role of treatment for older adults, preexisting cognitive impairment, and neurologic comorbidities.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating Anxiety's Impact on Seizure Quality in Electroconvulsive Therapy: A Prospective Observational Study. 调查焦虑对电休克治疗中癫痫发作质量的影响：一项前瞻性观察研究。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-17 DOI: 10.1097/YCT.0000000000001097

Kaissar Sassi, Etienne Bechet, Louise Martin, Manuel Pichon, Antoine Yrondi, Vincent Minville

{"title":"Investigating Anxiety's Impact on Seizure Quality in Electroconvulsive Therapy: A Prospective Observational Study.","authors":"Kaissar Sassi, Etienne Bechet, Louise Martin, Manuel Pichon, Antoine Yrondi, Vincent Minville","doi":"10.1097/YCT.0000000000001097","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001097","url":null,"abstract":"Background: Electroconvulsive therapy (ECT) is a medical procedure for treating severe depression and other mental health disorders, with anesthesia management being crucial for patient safety. Despite extensive research on factors influencing seizure quality during ECT, the impact of pre-ECT anxiety remains insufficiently explored.Methods: This prospective observational study aimed to investigate the influence of pre-ECT anxiety, as measured by the Amsterdam Preoperative Anxiety and Information Scale, on electroencephalogram ictal characteristics during ECT and to explore anesthesia-related factors that may enhance seizure quality.Results: A total of 38 patients participated in 168 documented ECT sessions over a 2-month period. Data analysis revealed a significant association between higher levels of pre-ECT anxiety, lidocaine doses exceeding 0.36 mg/kg, and decreased seizure quality during ECT sessions.Conclusion: These findings suggest an association between pre-ECT anxiety, lidocaine dosage, and decreased seizure quality during ECT. Further research, including interventional studies, is required to better understand the causal factors.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular Positron Emission Tomography and Single-Photon Emission Computed Tomography Imaging for Understanding the Neurobiological Mechanisms of Electroconvulsive Therapy: A Scoping Review. 分子正电子发射断层扫描和单光子发射计算机断层扫描成像用于理解电休克治疗的神经生物学机制：范围综述。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-17 DOI: 10.1097/YCT.0000000000001094

Maarten Laroy, Koen Van Laere, Mathieu Vandenbulcke, Louise Emsell, Filip Bouckaert

{"title":"Molecular Positron Emission Tomography and Single-Photon Emission Computed Tomography Imaging for Understanding the Neurobiological Mechanisms of Electroconvulsive Therapy: A Scoping Review.","authors":"Maarten Laroy, Koen Van Laere, Mathieu Vandenbulcke, Louise Emsell, Filip Bouckaert","doi":"10.1097/YCT.0000000000001094","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001094","url":null,"abstract":"Abstract: Electroconvulsive therapy (ECT) effectively treats severe psychiatric disorders such as depression, mania, catatonia, and schizophrenia. Although its exact mechanism remains unclear, ECT is thought to induce neurochemical and neuroendocrine changes. Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) have provided vital insights into ECT's neurobiological effects. This scoping review investigates the role of molecular imaging in understanding these effects. A systematic search across PubMed, EMBASE, Web of Science, Cochrane, and Scopus databases yielded 857 unique records, from which 45 peer-reviewed articles in English with longitudinal PET or SPECT measures in ECT patients were included. The review identifies 2 main research directions: ECT's impact on brain activity and neurotransmitters. Initial research assessed regional cerebral blood flow and regional glucose metabolism during ictal (during ECT), postictal (within 24 hours), short-term (within a week), and long-term (beyond a week) follow-up as markers of brain activity. Initial findings showed an anterior-posterior regional cerebral blood flow gradient during the ictal phase, with subsequent normalization of hypoperfusion in frontal and parietal regions, and persistent long-term effects. Later, research shifted to the monoamine hypothesis of depression, examining ECT's impact on serotonin and dopamine systems via PET imaging. Results on receptor availability post-ECT were mixed, showing both reductions and no significant changes, indicating variable effects. This scoping review further highlights the need to explore new targets, tailor methodologies for patient populations, and foster multicenter studies. Although SPECT has been valuable, advances in PET imaging now make it preferable, offering unparalleled insights into ECT's molecular and neurobiological mechanisms.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Cranial Sutures Should Be Considered in Transcranial Electrical Stimulation. 经颅电刺激应考虑颅缝的影响。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-10 DOI: 10.1097/YCT.0000000000001079

Alistair Carroll, Caroline D Rae, Donel Martin, Socrates Dokos, Colleen Loo

{"title":"The Effect of Cranial Sutures Should Be Considered in Transcranial Electrical Stimulation.","authors":"Alistair Carroll, Caroline D Rae, Donel Martin, Socrates Dokos, Colleen Loo","doi":"10.1097/YCT.0000000000001079","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001079","url":null,"abstract":"Background: Computational modeling is used to optimize transcranial electrical stimulation (tES) approaches, and the precision of these models is dependent on their anatomical accuracy. We are unaware of any computational modeling of tES that has included cranial sutures.Objectives: The aims of the study were to review the literature on the timing of closure of the coronal and squamous sutures, which are situated under electrode placements used in tES; to review the literature regarding differences in skull and suture conductivity and to determine a more accurate conductivity for sutures; and to identify magnetic resonance image (MRI) techniques that could be used to detect cranial sutures.Methods: A scoping review of medical literature was conducted. We conducted computational modeling of a cranial bone plug using COMSOL Multiphysics finite element software, utilizing methodology and results from a previous study. We assessed use of the \"3D Slicer\" software to identify sutures in routine T1-weighted MRI scans.Results: Reports from forensic examinations and computed tomography (CT) scans showed suture closure does not correlate with age. Our computational modeling determined a cranial suture conductivity of 0.32 S/m, which is much higher than for skull (compact skull 0.004 S/m, standard trilayer 0.013 S/m). 3D slicer enabled rapid and precise identification of the anatomy and location of cranial sutures.Conclusions: Cranial sutures persist throughout the lifespan and have a far higher conductivity than skull bone. Cranial sutures can be localized quickly and precisely using a combination of MRI and readily available modeling software. Sutures should be included in tES computational modeling and electroencephalography source imaging to improve the accuracy of results.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep Transcranial Magnetic Stimulation Using H7 Coil in Somatic Symptoms Disorder: A Case Report. H7线圈深经颅磁刺激治疗躯体症状障碍1例

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-06 DOI: 10.1097/YCT.0000000000001088

Sachin Reddy, Shyam Sundar Arumugham

引用次数: 0

Dexmedetomidine and Nitrous Oxide as Anesthetic Agents for Electroconvulsive Therapy: A Case Report. 右美托咪定和氧化亚氮作为电休克治疗的麻醉剂：1例报告。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-03 DOI: 10.1097/YCT.0000000000001096

In Won Chung, Heung Sik Kim, Junhee Lee, Jee Hee Kim, Sang Ha Kim, Yong Sik Kim

{"title":"Dexmedetomidine and Nitrous Oxide as Anesthetic Agents for Electroconvulsive Therapy: A Case Report.","authors":"In Won Chung, Heung Sik Kim, Junhee Lee, Jee Hee Kim, Sang Ha Kim, Yong Sik Kim","doi":"10.1097/YCT.0000000000001096","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001096","url":null,"abstract":"Abstract: Electroconvulsive therapy (ECT) is a therapeutic intervention that induces generalized seizures under general anesthesia. This case report compares the efficacy of dexmedetomidine (DEX) and nitrous oxide (N2O) to that of propofol during ECT procedures. A 33-year-old woman with a 15-year history of schizophrenia and recurrent psychotic episodes underwent ECT. During a previous hospitalization, she underwent 14 ECT sessions using propofol and succinylcholine. The mean electrical stimulation dose was 598.9 ± 237.6 mC, with mean motor and electroencephalogram seizure durations of 23.8 ± 8.0 and 34.9 ± 8.3 seconds, respectively. During her current hospitalization, she underwent an additional 14 ECT sessions using DEX and N2O. The mean electrical stimulation dose was significantly lower, at 239.4 ± 54.7 mC, with comparable motor and electroencephalogram seizure durations of 34.6 ± 11.6 and 36.3 ± 12.5 seconds, respectively. Our case report emphasizes the effectiveness of using DEX and N2O for ECT anesthesia compared to propofol. Despite a significantly lower mean electrical stimulation dose requirement with DEX and N2O (t = 5.5155, P < 0.00001), no significant differences were observed in electroencephalogram seizure duration between the groups.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Practice of Electroconvulsive Therapy in Catalonia in 2022: Results From a Large Cross-Sectional Survey. 2022年加泰罗尼亚电痉挛治疗的实践：来自一项大型横断面调查的结果。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-03 DOI: 10.1097/YCT.0000000000001091

Joaquín Gil-Badenes, Carlo Alemany, Maria Iglesias, Aida de Arriba, Quintí Foguet-Boreu, Rosa Hernández-Ribas, Maria Isabel Carrión, Oscar Alcoverro, Salvatore Aguilar Ortiz, Aurora Torrent, Adriana Bassa, Laura Ros, Dani Bergé, Anna Giménez-Palomo, Mikel Urretavizcaya, Erika Martinez-Amoros

{"title":"Practice of Electroconvulsive Therapy in Catalonia in 2022: Results From a Large Cross-Sectional Survey.","authors":"Joaquín Gil-Badenes, Carlo Alemany, Maria Iglesias, Aida de Arriba, Quintí Foguet-Boreu, Rosa Hernández-Ribas, Maria Isabel Carrión, Oscar Alcoverro, Salvatore Aguilar Ortiz, Aurora Torrent, Adriana Bassa, Laura Ros, Dani Bergé, Anna Giménez-Palomo, Mikel Urretavizcaya, Erika Martinez-Amoros","doi":"10.1097/YCT.0000000000001091","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001091","url":null,"abstract":"Introduction: The practice of electroconvulsive therapy (ECT) exhibits variability across various domains, both between regions, and between centers within the same region. The ECT Working Group of the Catalan Society of Psychiatry conducted a comprehensive survey in Catalonia, Spain, to assess the current status of those variables essential in the clinical practice of ECT.Materials and methods: The survey comprised 50 items, including various question types such as multiple-choice, numerical response, and open-ended questions. It was administered to the 20 public hospitals that currently provide ECT in Catalonia during the year 2022. Information was gathered on 4 main areas: Organization of the ECT Unit, Specific Technique of ECT Application, Strategies and Organization of the Therapeutic Plan, and Epidemiological Data, Training, and Healthcare Resource Management.Results: Some notable findings include an application rate of 1.1 per 10,000 inhabitants, major depression diagnosis as the primary indication for ECT in 80% of the centers, and the ability to perform maintenance ECT in 100% of centers.Conclusions: Following the survey and analysis, 3 main findings emerged: minimal variation in ECT application rates compared to the previous decade, increased complexity in current ECT practices with a focus on quality and patient safety, and identified areas for improvement in resource management and the necessity for a well-trained and stable multidisciplinary team.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Response to Electroconvulsive Therapy in a Young Adult With Down Syndrome Regression Disorder. 电惊厥治疗唐氏综合症退行性障碍的临床反应。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-03 DOI: 10.1097/YCT.0000000000001093

Brendan J Kelley, Kala J Bailey, Joshua J Hubregsen

引用次数: 0

Relatives' Knowledge, Attitudes, and Experiences Toward Electroconvulsive Therapy: A Systematic Review. 亲属对电休克治疗的知识、态度和经验：系统回顾。

IF 1.8 4区医学

Journal of Ect Pub Date : 2024-12-03 DOI: 10.1097/YCT.0000000000001083

Klaus Boone, Pieter-Jan Geerts, Nele Van de Velde, Sofie Verhaeghe, Gilbert M D Lemmens

{"title":"Relatives' Knowledge, Attitudes, and Experiences Toward Electroconvulsive Therapy: A Systematic Review.","authors":"Klaus Boone, Pieter-Jan Geerts, Nele Van de Velde, Sofie Verhaeghe, Gilbert M D Lemmens","doi":"10.1097/YCT.0000000000001083","DOIUrl":"https://doi.org/10.1097/YCT.0000000000001083","url":null,"abstract":"Abstract: Electroconvulsive therapy (ECT) is an effective treatment for patients with severe psychiatric disorders. Stigma and lack of knowledge surrounding ECT are major obstacles for both patients and their caregivers, who play an important role as shared decision-makers. Insight in caregivers' perspectives on ECT can support the consent process and patient compliance with ECT. We aimed to review perspectives on knowledge, attitudes, and experiences of caregivers of adult and adolescent patients who received ECT. We performed a computerized search (EMBASE, MEDLINE) for articles meeting the following inclusion criteria: (1) qualitative studies, quantitative studies, or quasi-experimental studies that (2) report on caregiver perspectives of patients who received ECT. We conducted our systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method. In total, 29 articles were included. Variation in knowledge about ECT was high among caregivers. Their attitudes were generally positive and most would advise for future ECT if necessary. Psychoeducational tools and ECT experience increased knowledge and attitudes in caregivers. In general, caregivers were satisfied with ECT but wanted more information on risks and side effects before ECT. Caregivers reported more positive attitudes toward and had better experiences with ECT compared with patients. Our systematic review demonstrated moderate knowledge, but overall positive attitudes and experiences on ECT in caregivers. Overall low methodological quality of included studies limits our conclusions. Future research should focus more on qualitative methods and cohort studies.","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0