Journal of Ect最新文献

{"title":"New-Onset Atrial Fibrillation After Electroconvulsive Therapy: A Case Report and Clinical Implications.","authors":"Maria Miguel Amaral Dos Santos Figueiredo, Pedro Miguel Azevedo Afonso","doi":"10.1097/YCT.0000000000001169","DOIUrl":"10.1097/YCT.0000000000001169","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e12-e13"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating Anxiety's Impact on Seizure Quality in Electroconvulsive Therapy: A Prospective Observational Study.","authors":"Kaissar Sassi, Etienne Bechet, Louise Martin, Manuel Pichon, Antoine Yrondi, Vincent Minville","doi":"10.1097/YCT.0000000000001097","DOIUrl":"10.1097/YCT.0000000000001097","url":null,"abstract":"<p><strong>Background: </strong>Electroconvulsive therapy (ECT) is a medical procedure for treating severe depression and other mental health disorders, with anesthesia management being crucial for patient safety. Despite extensive research on factors influencing seizure quality during ECT, the impact of pre-ECT anxiety remains insufficiently explored.</p><p><strong>Methods: </strong>This prospective observational study aimed to investigate the influence of pre-ECT anxiety, as measured by the Amsterdam Preoperative Anxiety and Information Scale, on electroencephalogram ictal characteristics during ECT and to explore anesthesia-related factors that may enhance seizure quality.</p><p><strong>Results: </strong>A total of 38 patients participated in 168 documented ECT sessions over a 2-month period. Data analysis revealed a significant association between higher levels of pre-ECT anxiety, lidocaine doses exceeding 0.36 mg/kg, and decreased seizure quality during ECT sessions.</p><p><strong>Conclusion: </strong>These findings suggest an association between pre-ECT anxiety, lidocaine dosage, and decreased seizure quality during ECT. Further research, including interventional studies, is required to better understand the causal factors.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"1-4"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Efficacy of Continuous Theta Burst \"Intensive\" Posterior Parietal Cortex Stimulation in Generalized Anxiety Disorder: A Randomized Double-Blind Sham-Controlled Trial.","authors":"Sarthak Bhandari, Mohan Dhyani, Shobit Garg, Sai Krishna Tikka","doi":"10.1097/YCT.0000000000001131","DOIUrl":"10.1097/YCT.0000000000001131","url":null,"abstract":"<p><strong>Objectives: </strong>Citing nonresponse to conventional treatments, neuromodulation based treatments are needed in generalized anxiety disorder (GAD). Data regarding continuous TBS (cTBS) in GAD has been anecdotal. Citing right posterior parietal cortex (PPC) hyperconnectivity in GAD, we aimed to study the effect of intensive cTBS targeting PPC in a randomized rater-blinded placebo-control design.</p><p><strong>Material and methods: </strong>Forty-four patients age range 18-59 years (baseline Hamilton Anxiety Rating Scale [HAM-A] score >18 or Clinical Global Impression Severity [CGI-S] score of ≥4) were randomly allocated to active cTBS (n = 22) and sham cTBS (n = 22) groups using block randomization method. They received 10 cTBS sessions, 2 sessions per day (total of 1200 pulses) for 5 days in a week at 80% motor threshold. HAM-A, World Health Organization's abbreviated quality of life assessment (WHOQOL-BREF), and CGI-S were assessed at baseline, after the last session, and at 2 weeks after cTBS with gender as covariate. Intention-to-treat analysis was conducted and missing values were replaced using the last observation carried forward method.</p><p><strong>Results: </strong>On repeated measures analysis of variance, a significant between-group time effect for HAM-A (F = 29.6; P  = 0.001; ηp2 = 0.420), CGI-S (F = 24.7; P  = 0.001; ηp2 = 0.376), and WHOQOL-BREF (F = 29.6; P  = 0.001; ηp2 = 0.420). Logs of odds of response of >50% improvement in HAM-A between active and sham groups is 3.27 (95% CI [0.345, 6.20]). No major side effects were reported and none discontinued the trial because of side effects.</p><p><strong>Conclusions: </strong>Our trial concludes that cTBS of posterior parietal cortex is safe, well-tolerated, and effective in GAD.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"51-56"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143631084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Adjunctive High-Frequency Deep Transcranial Magnetic Stimulation for Improving Negative Symptoms in Schizophrenia: A Feasibility Study.","authors":"Gulesh Kumar, Nishant Goyal, Aniruddha Mukherjee, Pooja Sharma, Dharani Ramamoorthy","doi":"10.1097/YCT.0000000000001124","DOIUrl":"10.1097/YCT.0000000000001124","url":null,"abstract":"<p><strong>Background: </strong>Negative symptoms of schizophrenia are disabling and respond inadequately to antipsychotic treatment. Hypofunctioning of cortical areas such as anterior cingulate cortex and medial prefrontal cortex has been implicated in negative symptoms. Repetitive transcranial magnetic stimulation is efficacious for the negative symptoms. Deep transcranial magnetic stimulation (dTMS) has the benefits of repetitive transcranial magnetic stimulation with the advantage of stimulating deeper brain targets.</p><p><strong>Objective: </strong>The aim of the study was to explore the efficacy of high-frequency dTMS for improving negative symptoms in schizophrenia.</p><p><strong>Methods: </strong>This was a sham-controlled, rater, and subject-blinded study. Forty-six patients were randomly assigned into active and sham groups. Ten sessions of high-frequency dTMS at 10 Hz were given at 100% of resting motor threshold using H7 coil over 2 weeks. The Positive and Negative Syndrome Scale, Scale for Assessment of Negative Symptoms, and Clinical Global Impressions were assessed at baseline, at 2 weeks, and at 4 weeks after completion of dTMS.</p><p><strong>Result: </strong>Forty-three patients completed the study. Although both active and sham groups shown improvement over the time, active dTMS group showed significant improvement in negative symptoms as indicated by significant improvement in the Scale for Assessment of Negative Symptoms score as compared to sham dTMS group ( P  = 0.003, η 2  = 0.158), further substantiated by improvement in negative subscale of Positive and Negative Syndrome Scale ( P  = 0.044, η 2  = 0.079).</p><p><strong>Discussion: </strong>Findings from our study suggest that adjunctive high-frequency dTMS significantly improves negative symptoms and severity of illness among patients with schizophrenia. Future studies with larger sample sizes will add our knowledge in the beneficial effects of this newer modality of noninvasive brain stimulation.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"31-36"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143631080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision High Definition-Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Perceptual Deficits in Childhood Disintegrative Disorder: A Case Study.","authors":"Sarnava Hazra, Shivani Gusain, Nishant Goyal, Pooja Daga","doi":"10.1097/YCT.0000000000001170","DOIUrl":"10.1097/YCT.0000000000001170","url":null,"abstract":"<p><strong>Abstract: </strong>High-definition transcranial direct current stimulation (HD-tDCS) offers targeted neuromodulation for neurological disorders. This case study reports its use in a 10-year-old boy with childhood disintegrative disorder and sensory hyposensitivity. After localizing deficits using auditory steady-state response with a Geodesic Transcranial Electrical Neuromodulation system, 20 HD-tDCS sessions were delivered to the left primary auditory cortex over 10 days. After treatment, Autism Treatment Evaluation Checklist scores showed a 66% improvement, with sensory gains in auditory (26%) and proprioceptive (50%) domains, sustained at 1-month, 3-month and 6-month follow-ups. The intervention was well-tolerated with no adverse effects, demonstrating HD-tDCS's potential as a viable treatment for sensory deficits in childhood disintegrative disorder.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e10-e11"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safe, Repeated Treatment With Electroconvulsive Therapy in Combination With KarXT.","authors":"Jason M Andrus, Sohag N Sanghani","doi":"10.1097/YCT.0000000000001168","DOIUrl":"10.1097/YCT.0000000000001168","url":null,"abstract":"<p><strong>Abstract: </strong>To our knowledge, no report has been made of safe concurrent treatment with the novel muscarinic antipsychotic agent KarXT and electroconvulsive therapy (ECT). The drug has the potential for influencing the ECT procedure as well as outcomes. These issues are explored in the context of a case in which KarXT and ECT were successfully combined safely and repeatedly.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e8-e9"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroconvulsive Therapy for Self-injurious Behavior in Autism Spectrum Disorders: Case Series.","authors":"Nam Young Lee, In Won Chung, Lee Elizabeth Wachtel, Yong Sik Kim","doi":"10.1097/YCT.0000000000001172","DOIUrl":"10.1097/YCT.0000000000001172","url":null,"abstract":"","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e13-e15"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Simulation-Based Electroconvulsive Therapy Education on Perception and Knowledge of Nursing Students: A Semiexperimental Study.","authors":"Gül Dikeç, Eda Özkara Şan","doi":"10.1097/YCT.0000000000001130","DOIUrl":"10.1097/YCT.0000000000001130","url":null,"abstract":"<p><strong>Objectives: </strong>Despite the recognized benefits and safety of electroconvulsive therapy (ECT) for treating mental disorders, negative perceptions persist among both the public and mental health professionals. This stigma is often rooted in historical practices and media portrayals, despite modern advancements in the technique. This study aimed to assess the impact of simulation-based ECT education on nursing students' perceptions and knowledge regarding ECT before and after the procedure.</p><p><strong>Methods: </strong>This study was planned to use a single-group pretest and posttest quasi-experimental design with a 3-month follow-up. Simulation-based ECT education involved 1 hour of theoretical instruction followed by hands-on learning using a high-fidelity mannequin. Final-year nursing students enrolled in a psychiatric and mental health nursing course were examined on their knowledge and perceptions of ECT before, immediately after, and 3 months following the intervention.</p><p><strong>Results: </strong>Students reported statistically significant improvements in their perception and knowledge levels after participating in the simulation-based ECT education. The results were similar at the 3-month follow-up.</p><p><strong>Conclusions: </strong>Simulation-based ECT education can be effectively integrated into both undergraduate and graduate nursing curricula to foster positive perceptions and enhance knowledge about ECT.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"46-50"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Cerebral Hemodynamic Among Patients With Schizophrenia or Bipolar Disorder Receiving Electroconvulsive Therapy: A Task-Related Functional Near-Infrared Spectroscopy Study.","authors":"Keng-Hong Chhoa, Soon-Kiat Chiang, Kheng-Yee Ong, Choon-Keat Yong, Bee-Zhen Ng, Siti-Zubaidah Othman, Roger S McIntyre, Jongkwan Choi, Jihyun Cha, Roger C Ho, Kok-Yoon Chee","doi":"10.1097/YCT.0000000000001110","DOIUrl":"10.1097/YCT.0000000000001110","url":null,"abstract":"<p><strong>Abstract: </strong>There remains a scarcity of studies to evaluate the treatment effect of electroconvulsive therapy (ECT). Functional near-infrared spectroscopy (fNIRS) offers a cost-effective method to measure cerebral hemodynamics. This study used fNIRS to evaluate the effect of ECT in patients suffering from schizophrenia or bipolar disorder (manic phase). Thirty patients with mania and 31 with schizophrenia were recruited. Each participant received 6 sessions of ECT. This study utilized the Positive and Negative Syndrome Scale, Young Mania Rating Scale, and fNIRS-verbal fluency test paradigm at baseline and after each session of ECT. The prefrontal cortex hemodynamic response during the performance of verbal fluency test was recorded via a commercial wireless high-density continuous-wave fNIRS system device. The effect of categorical and continuous variables was determined using Pearson's chi-square test and Student's t test or 1-way analysis of variance with Bonferroni-corrected post hoc pairwise comparison, respectively. Comparing the Positive and Negative Syndrome Scale and Young Mania Rating Scale scores between baseline, sessions 3 and 6, the scores were significantly decreased ( P  < 0.001), with both patient groups achieving more than 50% reduction in scores from baseline to session 6. The fNIRS also showed significant increases in oxy-hemoglobin levels (session 6 vs baseline) in the right ventrolateral prefrontal cortex and left dorsolateral prefrontal cortex for both patient groups ( P  < 0.05). There were significant correlations in the reduction of symptom severity and increase in HbO 2 levels in people with bipolar disorder (manic phase) and schizophrenia ( P  < 0.05). Monitoring the activation in the right ventrolateral prefrontal cortex and left dorsolateral prefrontal cortex is an objective ECT monitoring indicator for patients suffering from bipolar disorder (manic phase) or schizophrenia.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"11-18"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introduction of Electroconvulsive Therapy in Cameroon.","authors":"Michael Guy Toguem, Ikenna D Ebuenyi","doi":"10.1097/YCT.0000000000001156","DOIUrl":"10.1097/YCT.0000000000001156","url":null,"abstract":"<p><strong>Abstract: </strong>Electroconvulsive therapy (ECT) is an essential component of clinical practice in psychiatry. Unfortunately, there remain many obstacles to its routine adoption. In Africa, the use of ECT remains limited, and to our knowledge, there is no documented use of ECT in Francophone Sub-Saharan African countries. This article shares our experience in establishing and providing ECT services at a center in Cameroon, which, to the best of our knowledge, is the only known ECT unit in Francophone Sub-Saharan African countries. We emphasize the need for governments and healthcare stakeholders to promote efforts to increase access to ECT in resource-limited settings.</p>","PeriodicalId":54844,"journal":{"name":"Journal of Ect","volume":" ","pages":"e3-e5"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}