Journal of Epidemiology and Community Health最新文献_第7页

Effect of social support on memory ageing of middle-aged and older cancer survivors: a marginal structural modelling approach. 社会支持对中老年癌症幸存者记忆老化的影响：一种边缘结构建模方法。

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2024-222962

Ashly C Westrick, Xuexin Yu, Brendan O'Shea, Lindsay C Kobayashi

{"title":"Effect of social support on memory ageing of middle-aged and older cancer survivors: a marginal structural modelling approach.","authors":"Ashly C Westrick, Xuexin Yu, Brendan O'Shea, Lindsay C Kobayashi","doi":"10.1136/jech-2024-222962","DOIUrl":"https://doi.org/10.1136/jech-2024-222962","url":null,"abstract":"Background: While social support is associated with better cognitive health among cancer-free individuals, this relationship is understudied among cancer survivors. We investigated whether overall social support before and after a cancer diagnosis is related to post-diagnosis memory ageing, overall and by sex/gender.Methods: Data were from 2044 cancer survivors in the US Health and Retirement Study (HRS; n=1395) and English Longitudinal Study of Ageing (ELSA; n=649) from 2006 to 2018. Incident cancer diagnoses and memory function (immediate and delayed word recall) were assessed biennially. Social support was assessed every 4 years in the HRS and biennially in ELSA. We established three time points relative to a cancer diagnosis: pre-diagnosis (the wave prior to cancer diagnosis), time 1 post-diagnosis (the first wave after a cancer diagnosis) and time 2 post-diagnosis (the second wave after a cancer diagnosis). Multivariable-adjusted marginal structural models incorporating inverse probability of treatment and attrition weights estimated the relationship between overall social support and memory function post-diagnosis.Results: Prior to a cancer diagnosis, 45.1% of participants reported high social support. Cancer survivors reporting higher social support at time 2 had better memory function post-diagnosis than those with lower social support (0.14 SD units; 95% CI: 0.03 to 0.24) which was stronger among women (0.18 SD units; 95% CI: 0.02 to 0.34) than men (0.10 SD units; 95% CI: -0.03 to 0.24).Conclusions: Social support may help promote memory function after a cancer diagnosis in mid-to-later life. Further studies with a larger sample size and differentiation of social support are warranted.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frailty or sarcopenia: which is a better indicator of mortality risk in older adults? 虚弱还是肌肉疏松症：哪个是老年人死亡风险的更好指标？

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2024-222678

Aline Fernanda de Souza, Paula Camila Ramírez, Dayane Capra de Oliveira, Roberta de Oliveira Máximo, Mariane Marques Luiz, Maicon Luis Bicigo Delinocente, Maria Claudia Bernardes Spexoto, Andrew Steptoe, Cesar De Oliveira, Tiago da Silva Alexandre

{"title":"Frailty or sarcopenia: which is a better indicator of mortality risk in older adults?","authors":"Aline Fernanda de Souza, Paula Camila Ramírez, Dayane Capra de Oliveira, Roberta de Oliveira Máximo, Mariane Marques Luiz, Maicon Luis Bicigo Delinocente, Maria Claudia Bernardes Spexoto, Andrew Steptoe, Cesar De Oliveira, Tiago da Silva Alexandre","doi":"10.1136/jech-2024-222678","DOIUrl":"10.1136/jech-2024-222678","url":null,"abstract":"Background: Despite the different conditions, frailty and sarcopenia overlap regarding their common link: the assessment of walking speed and muscle strength. This study aimed to compare the frailty phenotype to the sarcopenia using different cut-off points for low grip strength to determine which better identifies mortality risk over a 14-year follow-up period.Methods: 4597 participants in the English Longitudinal Study of Ageing. Frailty was measured using the Fried phenotype. Sarcopenia (European Working Group on Sarcopenia in Older People 2) was defined using different cut-off points for low grip strength (<36, <32, <30, <27 and <26 kg for men and <23, <21, <20 and <16 kg for women), low skeletal muscle mass index (<9.36 kg/m² for men and<6.73 kg/m² for women) and slowness (gait speed: ≤0.8 m/s). Cox models were run and adjusted for sociodemographic, behavioural and clinical factors.Results: When the coexistence of frailty and sarcopenia is considered, only the cut-off points <36 kg for men and <23 kg for women to define low grip strength identified the risk of mortality among individuals classified as having probable sarcopenia (HR=1.17, 95% CI 1.02 to 1.34), sarcopenia (HR=1.31, 95% CI 1.07 to 1.60) and severe sarcopenia (HR=1.62, 95% CI 1.33 to 1.96). In this situation, frailty identified the mortality risk (HR=1.49, 95% CI 1.22 to 1.81), whereas pre-frailty did not. Sarcopenia using other cut-off points for defining low grip strength did not identify mortality risk.Conclusion: Sarcopenia using <36 kg for men and <23 kg for women as cut-off points seems to be better than the frailty phenotype for identifying the risk of mortality in older adults.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"124-130"},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differences by ethnicity in the association between unpaid caring and health trajectories over 10 years in the UK Household Longitudinal Study. 英国家庭纵向研究》（Household Longitudinal Study）中 10 年间无偿照料与健康轨迹之间的种族差异。

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2024-222633

Whitney Wells, Baowen Xue, Rebecca Lacey, Anne McMunn

{"title":"Differences by ethnicity in the association between unpaid caring and health trajectories over 10 years in the UK Household Longitudinal Study.","authors":"Whitney Wells, Baowen Xue, Rebecca Lacey, Anne McMunn","doi":"10.1136/jech-2024-222633","DOIUrl":"10.1136/jech-2024-222633","url":null,"abstract":"Background: Unpaid carers deliver critical social care. We aimed to examine differences by ethnicity in (1) profiles of unpaid caring and (2) associations between caring and physical and mental health trajectories.Methods: We used 10 waves of data from 47 015 participants from the UK Household Longitudinal Study (2009-2020). Our outcomes were 12-item Short Form Health Survey physical and mental component scores. We performed bivariate comparison of profiles of caring by ethnicity. We used multilevel linear mixed effects models to estimate associations between caring and health trajectories and assess for heterogeneity by ethnicity.Results: We found that caring profiles differed by ethnicity. The proportion caring for someone within their household ranged from 39.7% of White carers to 70.1% of Pakistani and 74.8% of Bangladeshi carers. The proportion providing 20+ hours/week of care ranged from 26.9% of White carers to 40.6% of Pakistani and 43.3% of Black African carers. Ethnicity moderated associations between caring and physical but not mental health trajectories (test for interaction: p=0.038, p=0.75). Carers showed worse physical health compared with non-carers among Black African (-1.93; -3.52, -0.34), Bangladeshi (-2.01; -3.25, -0.78), Indian (-1.30; -2.33, -0.27) and Pakistani carers (-1.16; -2.25, -0.08); Bangladeshi carers' trajectories converged with non-carers over time (0.24; -0.02, 0.51). White carers showed better baseline physical health than non-carers (0.35; 0.10, 0.60), followed by worsening trajectories versus non-carers (-0.14; -0.18, -0.10).Conclusions: There are differences by ethnicity in profiles of caring and associations between caring and physical health trajectories. Future research should account for ethnicity to ensure applicability across groups.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"94-101"},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inequality in green space distribution and its association with preventable deaths across urban neighbourhoods in the UK, stratified by Index of Multiple Deprivation. 英国城市街区绿地分布的不平等及其与可预防死亡的关系，按多重贫困指数分层。

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2024-222485

Tran Thu Ngan, Ruoyu Wang, Christopher Tate, Mark Green, Richard Mitchell, Ruth F Hunter, Ciaran O'Neill

{"title":"Inequality in green space distribution and its association with preventable deaths across urban neighbourhoods in the UK, stratified by Index of Multiple Deprivation.","authors":"Tran Thu Ngan, Ruoyu Wang, Christopher Tate, Mark Green, Richard Mitchell, Ruth F Hunter, Ciaran O'Neill","doi":"10.1136/jech-2024-222485","DOIUrl":"10.1136/jech-2024-222485","url":null,"abstract":"Background: This study investigated inequalities in the distribution of green space (GS) and the association between inequalities in amounts of GS and preventable deaths across urban neighbourhoods with different Index of Multiple Deprivation (IMD) scores in the UK.Methods: Data on preventable deaths, IMD, percentage of grassland and woodland, urban/rural, population size, and density were sourced for each of 6791 middle-layer super output areas (MSOAs) in England, 410 MSOAs in Wales, 1279 intermediate zones (IZs) in Scotland, and 890 super output areas (SOAs) in Northern Ireland (NI). While appreciating the potential for ecological fallacy we related area-based measures of deprivation to deaths. Concentration curves, Lorenz dominance tests, and negative binomial regression models were used to analyse the data.Results: In urban areas of England, Scotland, and NI, the percentage of grassland was significantly lower among the more deprived neighbourhoods (Lorenz test, p<0.0001). In England, a 1% increase in grassland area was associated with a 37% reduction in annual preventable deaths among the most deprived urban MSOAs (incidence rate ratio (IRR) 0.63, 95% CI 0.52 to 0.76). In NI and Scotland, a 1% increase in grassland area was associated with a 37% (IRR 0.63, 95% CI 0.43 to 0.91) and 41% (IRR 0.59, 95% CI 0.42 to 0.81) reduction in 5-year accumulated preventable deaths in the most deprived urban SOAs/IZs, respectively.Conclusions: Results suggest that investment in GS in urban areas may be an important public health prevention strategy. There is evidence that investments in the most deprived urban neighbourhoods where the highest inequality currently exists would see the largest effect on preventable deaths.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"102-109"},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inequalities in adolescent mental health and allocation of students to selective classes in comprehensive schools in Finland: a longitudinal study. 芬兰综合学校中青少年心理健康的不平等现象与选择性班级的学生分配：一项纵向研究。

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2023-221854

Heidi Kesanto-Jokipolvi, Mari Siipola, Satu Koivuhovi, Terhi Pasu, Piia Seppänen, Arja Rimpelä

{"title":"Inequalities in adolescent mental health and allocation of students to selective classes in comprehensive schools in Finland: a longitudinal study.","authors":"Heidi Kesanto-Jokipolvi, Mari Siipola, Satu Koivuhovi, Terhi Pasu, Piia Seppänen, Arja Rimpelä","doi":"10.1136/jech-2023-221854","DOIUrl":"10.1136/jech-2023-221854","url":null,"abstract":"Background: Lower socioeconomic positions (SEP) and poor academic achievement increase children's risk for mental health problems. The Finnish education system is officially non-selective and unified, but a part of children can be selected into emphasised teaching classes by aptitude tests, which are known to segregate students by SEP and academic achievement. We study here if allocation of students to mainstream and selective classes segregates students by mental health, too.Methods: Students from primary school (6th grade) were followed to lower secondary school (7th grade). The number in selective classes was n=209 and in mainstream classes n=551. Outcomes were depressed mood, anxiety and daily health complaints. Association between class type and the outcomes was analysed by cross-tabulation and logistic regression models. Gender, academic achievement, SEP and previous mental health were independent and confounding/moderating variables.Results: Students in selective classes had better academic achievement and higher SEP compared with students in mainstream classes. Girls reported poorer mental health than boys. Depressive mood did not vary by class type, but anxiety and daily health complaints were more common among girls in mainstream classes. When academic achievement and background factors were considered, among girls only anxiety was more common in mainstream classes, but among boys, anxiety appeared to be statistically significantly more common in selective classes.Conclusion: Grouping students by aptitude tests to different classes may select them by mental health, too. Longer follow-up and gender-specific studies would give more reliable answers for education policy makers about student grouping by aptitude test and its effects on segregation.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"110-116"},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of congenital heart defects in people with Down syndrome: a systematic review and meta-analysis. 唐氏综合症患者先天性心脏缺陷的患病率：一项系统回顾和荟萃分析。

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2023-220638

Chen-Xi Xu, Lei Chen, Yong Cheng, Yang Du

{"title":"Prevalence of congenital heart defects in people with Down syndrome: a systematic review and meta-analysis.","authors":"Chen-Xi Xu, Lei Chen, Yong Cheng, Yang Du","doi":"10.1136/jech-2023-220638","DOIUrl":"https://doi.org/10.1136/jech-2023-220638","url":null,"abstract":"Background: The prevalence of congenital heart defects (CHD) in Down syndrome (DS) varies considerably across studies (from 16% to 84%). This study aimed to estimate the prevalence of CHD in people with DS (CHD-DS).Methods: PubMed, Web of Science and the Chinese National Knowledge Infrastructure databases were searched through to 5 January 2023. English-language and Chinese-language articles reporting data on the prevalence of CHD in people with DS were included. Two independent observers performed data extraction and we used a random effects model for all statistical analyses by the Comprehensive Meta-Analysis V.3.3.070 software.Results: A pooled analysis, based on 102 studies that included 60 610 individuals, revealed the prevalence of CHD was 49.9% (95% CI: 46.8% to 53.0%) in people with DS. Most of the studies included in this meta-analysis were from North America, Europe and Asia, and subgroup analyses showed a slightly higher prevalence of CHD-DS in Asia (27 studies) compared with North America (28 studies) and Europe (35 studies) (Asia vs North America vs Europe; 54.2% vs 51.6% vs 46.2%).Conclusion: These results demonstrated that approximately one-half of people with DS had CHD, reinforcing the need to screen all newborns suspected of Down syndrome for CHD.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overdose as a complex contagion: modelling the community spread of overdose events following law enforcement efforts to disrupt the drug market. 吸毒过量是一种复杂的传染病：在执法部门努力扰乱毒品市场后，吸毒过量事件的社区传播模型。

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2024-222263

Jamie L Humphrey, Clyde Schwab, Nicholas J Richardson, Barrot H Lambdin, Alex H Kral, Bradley Ray

{"title":"Overdose as a complex contagion: modelling the community spread of overdose events following law enforcement efforts to disrupt the drug market.","authors":"Jamie L Humphrey, Clyde Schwab, Nicholas J Richardson, Barrot H Lambdin, Alex H Kral, Bradley Ray","doi":"10.1136/jech-2024-222263","DOIUrl":"10.1136/jech-2024-222263","url":null,"abstract":"Background: The opioid overdose mortality crisis in the USA is an ongoing public health epidemic. Ongoing law enforcement strategies to disrupt local unregulated drug markets can have an iatrogenic effect of increasing overdose by driving consumers towards new suppliers with unpredictable drug products of unknown potency.Methods: Cross-sectional study using point-level information on law enforcement opioid-related drug seizures from property room data, opioid-related non-fatal overdose events from emergency medical services and block group-level social determinants of health data from multiple sources. Using an endemic-epidemic spatiotemporal regression model, we estimated the degree to which exposure to drug supply disruptions triggers future overdose events within small space-time distances in Indianapolis, Indiana.Results: Neighbourhoods with more structural racism, economic deprivation or urban blight were associated with higher rates of non-fatal overdose. Exposure to an opioid-related drug seizure event had a significant and positive effect on the epidemic probability of non-fatal overdose. An opioid seizure that occurred within 250 m and 3 days, 250 m and 7 days, and 250 m and 14 days of an overdose event increased the risk of a new non-fatal overdose by 2.62 (rate ratio (RR)=2.62, 95% CI 1.87 to 3.67), 2.17 (RR=2.17, 95% CI 1.87 to 2.59) and 1.83 (RR=1.83, 95% CI 1.66 to 2.02), respectively. Similar spatiotemporal patterns were observed in a smaller spatial bandwidth.Conclusions: Results demonstrated that overdoses exhibit a community spread process, which is exacerbated following law enforcement strategies to disrupt the unregulated drug market. We discuss decriminalisation and increasing resources that promote safer drug use to combat this public health crisis.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"147-152"},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in food habits during the transition to retirement: the Whitehall II cohort study. 向退休过渡期间饮食习惯的变化：怀特霍尔 II 队列研究。

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2024-222690

Hanna Lagström, Mirkka Lahdenperä, Chirsna Ravyse, Tasnime Akbaraly, Mika Kivimaki, Jaana Pentti, Sari Stenholm, Jenny Head

{"title":"Changes in food habits during the transition to retirement: the Whitehall II cohort study.","authors":"Hanna Lagström, Mirkka Lahdenperä, Chirsna Ravyse, Tasnime Akbaraly, Mika Kivimaki, Jaana Pentti, Sari Stenholm, Jenny Head","doi":"10.1136/jech-2024-222690","DOIUrl":"10.1136/jech-2024-222690","url":null,"abstract":"Background: The transition to retirement is a significant turning point in life, which may lead to changes in food habits.Objective: To examine changes in red meat, fish, vegetables and fruit consumption during the retirement transition and whether these changes vary between sociodemographic groups.Methods: The data were from the Whitehall II study, a cohort of 10 308 British civil servants aged 35-55 years at study induction (1985-1988). Data collection has taken place every 2-3 years. Food consumption (n=2484-2491) was assessed with the Food Frequency Questionnaire in the periods before (max. 16 years) and after retirement (max. 16 years). Changes in preretirement and postretirement consumption were compared in the total cohort and subgroups by sex, marital status, preretirement occupation status and financial hardship using linear regression analyses with generalised estimating equations.Results: Weekly red meat consumption was stable before retirement but increased after retirement (p=0.02), especially among women, single and lower occupational status participants. Fish consumption increased during the follow-up and the increase was steeper before retirement than postretirement period (p=0.02). Vegetable and fruit consumption also increased during the entire follow-up, but more strongly during preretirement than postretirement period (p<0.001 for both).Conclusion: The transition to retirement is accompanied by favourable (increase in fruit, vegetable and fish) and unfavourable (increase in red meat) dietary changes, varied to some extent by sex, marital status and preretirement occupational status. Our findings suggest that attention should be paid to this transitional phase to promote eating habits in accordance with the recommendations for retirement.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"131-137"},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Six-year change in high-sensitivity cardiac troponin T with subsequent stroke risk in the general population. 高敏心肌肌钙蛋白 T 的六年变化与普通人群后续中风风险的关系。

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2024-222517

Qiguo Meng, Xiaoqin Gan, Cheng Zu, Yuanyuan Zhang, Panpan He, Ziliang Ye, Xinyue Su, Yuanxiu Wei, Xianhui Qin

{"title":"Six-year change in high-sensitivity cardiac troponin T with subsequent stroke risk in the general population.","authors":"Qiguo Meng, Xiaoqin Gan, Cheng Zu, Yuanyuan Zhang, Panpan He, Ziliang Ye, Xinyue Su, Yuanxiu Wei, Xianhui Qin","doi":"10.1136/jech-2024-222517","DOIUrl":"10.1136/jech-2024-222517","url":null,"abstract":"Background: The association between change in high-sensitivity cardiac troponin T (hs-cTnT) and stroke risk in the general population remains unknown. We aimed to assess the association of a 6-year change in hs-cTnT with incident stroke and its subtypes in the general American adult population.Methods: 8675 middle-aged adults without prevalent cardiovascular disease from the Atherosclerosis Risk in Communities study were included. Hs-cTnT was measured at two time points (visits 2 and 4), 6 years apart. The relative percentage change of hs-cTnT was defined as hs-cTnT at visit 4 minus that at visit 2, divided by hs-cTnT at visit 2. The study outcome was incident stroke and its subtypes. All data were analysed in 2023.Results: Over a median follow-up of 20.1 years, 682 incident strokes occurred, including 593 ischaemic and 89 haemorrhagic strokes. For absolute change, using low/low group as reference category, the low/high (adjusted HR 1.44, 95% CI 1.03 to 2.02) and high/high (adjusted HR 1.47, 95% CI 0.93 to 2.34) groups were associated with higher risk of stroke. Moreover, the relative percentage change in hs-cTnT with stroke followed an inverted L-shaped association, levelling off at about 75% increase in hs-cTnT (P for nonlinearity=0.009). Compared with those with ≤50% change in hs-cTnT, participants with >50% increase in hs-cTnT had a higher risk of stroke (adjusted HR 1.30, 95% CI 1.03 to 1.64). Similar results were found for ischaemic stroke. No significant association was found for haemorrhagic stroke.Conclusion: Temporal increase in hs-cTnT was associated with a higher risk of incident total and ischaemic stroke in the general population.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"138-145"},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of same-sex marriage legalisation on the health of ethnic minority lesbian, gay and bisexual people: a quasi-experimental study. 同性婚姻合法化对少数民族女同性恋者、男同性恋者和双性恋者健康的影响：一项准实验研究。

IF 4.9 2区医学

Journal of Epidemiology and Community Health Pub Date : 2025-01-13 DOI: 10.1136/jech-2024-222651

Yihong Bai, Chungah Kim, Antony Chum

{"title":"Effect of same-sex marriage legalisation on the health of ethnic minority lesbian, gay and bisexual people: a quasi-experimental study.","authors":"Yihong Bai, Chungah Kim, Antony Chum","doi":"10.1136/jech-2024-222651","DOIUrl":"10.1136/jech-2024-222651","url":null,"abstract":"Background: The UK legalised same-sex marriage in 2014. We examine whether same-sex marriage legalisation (SSML), an exogenous policy change, affected the health outcomes among ethnic minority lesbian, gay, bisexual and other (LGB+) individuals.Methods: Using the UK Household Longitudinal Survey, we applied the Callaway and Sant'Anna difference-in-differences to compare physical and mental health across (a) ethnic LGB+ individuals (treatment group), (b) ethnic heterosexual individuals (control group 1) and (c) British white LGB+ individual (control group 2). The study cohort (n=7054) comprised individuals aged 16+ years at baseline in 2011, and were employed in the study period (2011-2019). The outcomes included physical component scores from the short-form 12 health survey (physical component score (PCS-12)), long-standing illnesses and psychological distress (General Health Questionnaire (GHQ)).Results: After SSML, the PCS-12 among the ethnic LGB+ individuals improved significantly compared with both ethnic heterosexuals and British white LGB+ individuals (2.081, 95% CI 0.487 to 3.675). While no clear patterns were found for long-standing illnesses, the GHQ in the treatment group had modest decreases relative to ethnic heterosexuals, and relative to British white LGB+ individuals, by year 2 after SSML.Conclusion: SSML in the UK led to improved physical functioning and reduced psychological distress in ethnic minority LGB+ individuals. Our study shows that ethnic LGB+ individuals may derive even greater health benefits than British white LGB+ people, providing evidence that SSML may help address racial health inequalities within LGB+ communities. As countries worldwide consider legalising same-sex marriage, it is imperative for policymakers to consider the health consequences for sexual and ethnic minorities.","PeriodicalId":54839,"journal":{"name":"Journal of Epidemiology and Community Health","volume":" ","pages":"117-123"},"PeriodicalIF":4.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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