Journal of Heredity最新文献_第4页

Together inbreeding and reproductive compensation favor lethal t-haplotypes. 近亲繁殖和生殖补偿共同有利于致命的 t-单倍型。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-23 DOI: 10.1093/jhered/esae030

Manisha Munasinghe, Yaniv Brandvain

{"title":"Together inbreeding and reproductive compensation favor lethal t-haplotypes.","authors":"Manisha Munasinghe, Yaniv Brandvain","doi":"10.1093/jhered/esae030","DOIUrl":"10.1093/jhered/esae030","url":null,"abstract":"Male mice who are heterozygous for distorting and non-distorting alleles at the t-haplotype transmit the driving t-haplotype around 90% of the time-a drastic departure from Mendelian expectations. This selfish act comes at a cost. The mechanism underlying transmission distortion in this system causes severe sterility in males homozygous for the drive alleles, ultimately preventing its fixation. Curiously, many driving t-haplotypes also induce embryonic lethality in both sexes when homozygous; however, this is neither universal nor a necessity for this distortion mechanism. Charlesworth provided an adaptive explanation for the evolution of lethal t-haplotypes in a population segregating for distorting and non-distorting t alleles-if mothers compensate by replacing dead embryos with new offspring (or by transferring energy to surviving offspring), a recessive lethal can be favored because it effectively allows mothers the opportunity to trade in infertile males for potentially fertile offspring. This model, however, requires near complete reproductive compensation for the invasion of the lethal t-haplotype and produces an equilibrium frequency of lethal drivers well below what is observed in nature. We show that low levels of systemic inbreeding, which we model as brother-sister mating, allow lethal t-haplotypes to invade with much lower levels of reproductive compensation. Furthermore, inbreeding allows these lethal haplotypes to largely displace the ancestral male-sterile haplotypes. Our results show that together inbreeding and reproductive compensation move expected equilibria closer to observed haplotype frequencies in natural populations and occur under lower, potentially more reasonable, parameters.","PeriodicalId":54811,"journal":{"name":"Journal of Heredity","volume":" ","pages":"672-681"},"PeriodicalIF":3.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Germline ecology: Managed herds, tolerated flocks, and pest control. 种系生态学：管理的畜群、耐受的羊群和害虫控制。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-23 DOI: 10.1093/jhered/esae004

David Haig

引用次数: 0

Autosomal suppression of sex-ratio meiotic drive influences the dynamics of X and Y chromosome coevolution. 常染色体对性比减数分裂驱动力的抑制影响了 X 和 Y 染色体共同进化的动态。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-23 DOI: 10.1093/jhered/esae048

Anjali Gupta, Robert L Unckless

{"title":"Autosomal suppression of sex-ratio meiotic drive influences the dynamics of X and Y chromosome coevolution.","authors":"Anjali Gupta, Robert L Unckless","doi":"10.1093/jhered/esae048","DOIUrl":"10.1093/jhered/esae048","url":null,"abstract":"Sex-ratio meiotic drivers are selfish genes or gene complexes that bias the transmission of sex chromosomes resulting in skewed sex ratios. Existing theoretical models have suggested the maintenance of a four-chromosome equilibrium (with driving and standard X and suppressing and susceptible Y) in a cyclic dynamic, but studies of natural populations have failed to capture this pattern. Although there are several plausible explanations for this lack of cycling, interference from autosomal suppressors has not been studied using a theoretical population genetic framework even though autosomal suppressors and Y-linked suppressors coexist in natural populations of some species. In this study, we use a simulation-based approach to investigate the influence of autosomal suppressors on the cycling of sex chromosomes. Our findings demonstrate that the presence of an autosomal suppressor can hinder the invasion of a Y-linked suppressor under some parameter space, thereby impeding the cyclic dynamics, or even the invasion of Y-linked suppression. Even when a Y-linked suppressor invades, the presence of an autosomal suppressor can prevent cycling. Our study demonstrates the potential role of autosomal suppressors in preventing sex chromosome cycling and provides insights into the conditions and consequences of maintaining both Y-linked and autosomal suppressors.","PeriodicalId":54811,"journal":{"name":"Journal of Heredity","volume":" ","pages":"660-671"},"PeriodicalIF":3.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of conflict in the formation and maintenance of variant sex chromosome systems in mammals. 冲突在哺乳动物变异性染色体系统的形成和维持中的作用。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-23 DOI: 10.1093/jhered/esae031

Jonathan J Hughes, German Lagunas-Robles, Polly Campbell

{"title":"The role of conflict in the formation and maintenance of variant sex chromosome systems in mammals.","authors":"Jonathan J Hughes, German Lagunas-Robles, Polly Campbell","doi":"10.1093/jhered/esae031","DOIUrl":"10.1093/jhered/esae031","url":null,"abstract":"The XX/XY sex chromosome system is deeply conserved in therian mammals, as is the role of Sry in testis determination, giving the impression of stasis relative to other taxa. However, the long tradition of cytogenetic studies in mammals documents sex chromosome karyotypes that break this norm in myriad ways, ranging from fusions between sex chromosomes and autosomes to Y chromosome loss. Evolutionary conflict, in the form of sexual antagonism or meiotic drive, is the primary predicted driver of sex chromosome transformation and turnover. Yet conflict-based hypotheses are less considered in mammals, perhaps because of the perceived stability of the sex chromosome system. To address this gap, we catalog and characterize all described sex chromosome variants in mammals, test for family-specific rates of accumulation, and consider the role of conflict between the sexes or within the genome in the evolution of these systems. We identify 152 species with sex chromosomes that differ from the ancestral state and find evidence for different rates of ancestral to derived transitions among families. Sex chromosome-autosome fusions account for 79% of all variants whereas documented sex chromosome fissions are limited to three species. We propose that meiotic drive and drive suppression provide viable explanations for the evolution of many of these variant systems, particularly those involving autosomal fusions. We highlight taxa particularly worthy of further study and provide experimental predictions for testing the role of conflict and its alternatives in generating observed sex chromosome diversity.","PeriodicalId":54811,"journal":{"name":"Journal of Heredity","volume":" ","pages":"601-624"},"PeriodicalIF":3.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141249078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

United by conflict: Convergent signatures of parental conflict in angiosperms and placental mammals. 因冲突而团结：被子植物和胎生哺乳动物亲子冲突的趋同特征。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-23 DOI: 10.1093/jhered/esae009

Hagar K Soliman, Jenn M Coughlan

{"title":"United by conflict: Convergent signatures of parental conflict in angiosperms and placental mammals.","authors":"Hagar K Soliman, Jenn M Coughlan","doi":"10.1093/jhered/esae009","DOIUrl":"10.1093/jhered/esae009","url":null,"abstract":"Endosperm in angiosperms and placenta in eutherians are convergent innovations for efficient embryonic nutrient transfer. Despite advantages, this reproductive strategy incurs metabolic costs that maternal parents disproportionately shoulder, leading to potential inter-parental conflict over optimal offspring investment. Genomic imprinting-parent-of-origin-biased gene expression-is fundamental for endosperm and placenta development and has convergently evolved in angiosperms and mammals, in part, to resolve parental conflict. Here, we review the mechanisms of genomic imprinting in these taxa. Despite differences in the timing and spatial extent of imprinting, these taxa exhibit remarkable convergence in the molecular machinery and genes governing imprinting. We then assess the role of parental conflict in shaping evolution within angiosperms and eutherians using four criteria: 1) Do differences in the extent of sibling relatedness cause differences in the inferred strength of parental conflict? 2) Do reciprocal crosses between taxa with different inferred histories of parental conflict exhibit parent-of-origin growth effects? 3) Are these parent-of-origin growth effects caused by dosage-sensitive mechanisms and do these loci exhibit signals of positive selection? 4) Can normal development be restored by genomic perturbations that restore stoichiometric balance in the endosperm/placenta? Although we find evidence for all criteria in angiosperms and eutherians, suggesting that parental conflict may help shape their evolution, many questions remain. Additionally, myriad differences between the two taxa suggest that their respective biologies may shape how/when/where/to what extent parental conflict manifests. Lastly, we discuss outstanding questions, highlighting the power of comparative work in quantifying the role of parental conflict in evolution.","PeriodicalId":54811,"journal":{"name":"Journal of Heredity","volume":" ","pages":"625-642"},"PeriodicalIF":3.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11498613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139747779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A chromosome-level genome assembly for the desert scorpion Mesobuthus przewalskii from Asian drylands. 亚洲旱地沙漠蝎 Mesobuthus przewalskii 染色体级基因组组装。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-21 DOI: 10.1093/jhered/esae059

Yan-Kai Su, Ming-Hua Xiu, Hao-Yan Yang, Cheng-Min Shi

引用次数: 0

Frequencies of house fly proto-Y chromosomes across populations are predicted by temperature heterogeneity within populations. 家蝇原 Y 染色体在不同种群中的频率是由种群内的温度异质性预测的。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-15 DOI: 10.1093/jhered/esae056

Patrick D Foy, Sara R Loetzerich, David Boxler, Edwin R Burgess, R T Trout Fryxell, Alec C Gerry, Nancy C Hinkle, Erika T Machtinger, Cassandra Olds, Aaron M Tarone, Wes Watson, Jeffrey G Scott, Richard P Meisel

{"title":"Frequencies of house fly proto-Y chromosomes across populations are predicted by temperature heterogeneity within populations.","authors":"Patrick D Foy, Sara R Loetzerich, David Boxler, Edwin R Burgess, R T Trout Fryxell, Alec C Gerry, Nancy C Hinkle, Erika T Machtinger, Cassandra Olds, Aaron M Tarone, Wes Watson, Jeffrey G Scott, Richard P Meisel","doi":"10.1093/jhered/esae056","DOIUrl":"https://doi.org/10.1093/jhered/esae056","url":null,"abstract":"Sex chromosomes often differ between closely related species and can even be polymorphic within populations. Species with multifactorial sex determination segregate for multiple different sex determining loci within populations, making them uniquely informative of the selection pressures that drive the evolution of sex chromosomes. The house fly (Musca domestica) is a model species for studying multifactorial sex determination because male determining genes have been identified on all six of the chromosomes, which means that any chromosome can be a \"proto-Y\". Natural populations of house fly also segregate for a recently derived female-determining locus, meaning house flies also have a proto-W chromosome. The different proto-Y chromosomes are distributed along latitudinal clines on multiple continents, their distributions can be explained by seasonality in temperature, and they have temperature-dependent effects on physiological and behavioral traits. It is not clear, however, how the clinal distributions interact with the effect of seasonality on the frequencies of house fly proto-Y and proto-W chromosomes across populations. To address this question, we measured the frequencies of house fly proto-Y and proto-W chromosomes across nine populations in the United States of America. We confirmed the clinal distribution along the eastern coast of North America, but it is limited to the eastern coast. In contrast, annual mean daily temperature range predicts proto-Y chromosome frequencies across the entire continent. Our results therefore suggest that temperature heterogeneity can explain the distributions of house fly proto-Y chromosomes in a way that does not depend on the cline.","PeriodicalId":54811,"journal":{"name":"Journal of Heredity","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maintaining Breed Integrity: Successful Introgression of the SLICK1 Allele into the Holstein Breed. 保持品种完整性：将 SLICK1 等位基因成功引入荷斯坦品种。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-14 DOI: 10.1093/jhered/esae057

Gabriel A Zayas, Serdal Dikmen, Raluca G Mateescu, Peter J Hansen

{"title":"Maintaining Breed Integrity: Successful Introgression of the SLICK1 Allele into the Holstein Breed.","authors":"Gabriel A Zayas, Serdal Dikmen, Raluca G Mateescu, Peter J Hansen","doi":"10.1093/jhered/esae057","DOIUrl":"https://doi.org/10.1093/jhered/esae057","url":null,"abstract":"This study evaluated the effectiveness of genetic introgression of the SLICK1 allele derived from Senepol cattle into the Holstein breed to enhance thermotolerance. The SLICK1 allele, located in PRLR gene, confers a short and sleek coat that is inherited as a simple dominant phenotype. Approximately 40 years ago, the University of Florida initiated efforts to introgress this allele into the Holstein population. Here we tracked the introgression of the SLICK1 allele using a medium-density genotyping array and a reference population of both breeds (50 Holstein, 46 Senepol). Among the 31 SLICK1+ Holsteins, there was 15.25% ± 11.11% (mean ± SD) Senepol ancestry on BTA20. Holsteins at the University of Florida descended from slick matings that did not inherit the SLICK1 allele (n=9) exhibited no Senepol ancestry. A secondary introgression of Senepol genetics in SLICK1+ animals was found on BTA4, spanning 54 markers and 15 genes, with 26.67% Senepol ancestry. This region, previously linked to heat stress adaptation, suggests that the introgression extends beyond the SLICK1 allele to incorporate additional beneficial genetics for thermal stress adaptation. These findings indicate that deliberate introgression of the SLICK1 allele enhances specific traits and potentially introduces other adaptive genetic variations. The study demonstrates the successful use of genetic interventions to improve livestock resilience against environmental challenges without significantly disrupting the recipient breed's genetic structure. The introgression of the SLICK1 allele serves as a model for breeding programs aimed at optimizing animal welfare and productivity in the face of global climate change while maintaining breed integrity.","PeriodicalId":54811,"journal":{"name":"Journal of Heredity","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reference genome for the endangered, genetically subdivided, northern tidewater goby, Eucyclogobius newberryi. 濒危、基因细分的北部潮水虾虎鱼 Eucyclogobius newberryi 的参考基因组。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-05 DOI: 10.1093/jhered/esae053

David K Jacobs, Andrew Kinziger, Mira Abrecht, W Tyler McCraney, Benjamin A Hà, Brenton T Spies, Elizabeth Heath-Heckman, Mohan P A Marimuhtu, Oanh Nguyen, Colin W Fairbairn, William E Seligmann, Merly Escalona, Courtney Miller, H Bradley Shaffer

{"title":"Reference genome for the endangered, genetically subdivided, northern tidewater goby, Eucyclogobius newberryi.","authors":"David K Jacobs, Andrew Kinziger, Mira Abrecht, W Tyler McCraney, Benjamin A Hà, Brenton T Spies, Elizabeth Heath-Heckman, Mohan P A Marimuhtu, Oanh Nguyen, Colin W Fairbairn, William E Seligmann, Merly Escalona, Courtney Miller, H Bradley Shaffer","doi":"10.1093/jhered/esae053","DOIUrl":"https://doi.org/10.1093/jhered/esae053","url":null,"abstract":"The federally endangered sister species, Eucyclogobius newberryi (northern tidewater goby) and E. kristinae (southern tidewater goby) comprise the California endemic genus Eucyclogobius, which historically occurred in all coastal California counties. Isolated lagoons that only intermittently connect to the sea are their primary habitat. Reproduction occurs during lagoon closure, minimizing marine dispersal and generating the most genetically subdivided vertebrate genus on the California coast. We present a new genome assembly for E. newberryi using HiFi long reads and Hi-C chromatin-proximity sequencing. The 980Mb E. newberryi reference genome has an N50 of 34Mb with 22 well-described scaffolds comprising 88% of the genome and a complete BUSCO score of 96.7%. This genome will facilitate studies addressing selection, drift, and metapopulation genetics in subdivided populations, as well as the persistence of the critically endangered E. kristinae, where reintroduction will be an essential element of conservation actions for recovery. It also provides tools critical to the recovery of the genetically distinct management units in the northern tidewater goby, as well as broader ecological and evolutionary studies of gobies, the most speciose family of fishes in the world.","PeriodicalId":54811,"journal":{"name":"Journal of Heredity","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The genome of the Australian water dragon (Intellagama lesueurii), an agamid model for urban adaptation. 澳大利亚水龙（Intellagama lesueurii）的基因组--城市适应性的蚕食模式。

IF 3 2区生物学

Journal of Heredity Pub Date : 2024-10-04 DOI: 10.1093/jhered/esae054

Daniel Powell, Nicola Jackson, Parwinder Kaur, Olga Dudchenko, Erez Lieberman Aiden, Arthur Georges, Céline H Frère

引用次数: 0