New Microbiologica最新文献_第6页

Successful control measures to treat the transmission of Candida auris in Northern Italian Hospital. 成功控制意大利北部医院的念珠菌传播。

IF 1.8 4区医学

New Microbiologica Pub Date : 2024-01-01

Federico Giovagnorio, Nicholas Geremia, Claudio Scarparo, Sandro Panese, Simone Bradariolo, Chiara Berti, Maria Solinas, Maurizio Sanguinetti, Vittorio Selle, Andrea Cozza, Saverio Giuseppe Parisi, Giovanni Carretta

引用次数: 0

18S rRNA sequencing and homology analysis of post-traumatic bloodstream infection with Saprochaete clavata (Magnusiomyces clavatus) and a case report. 创伤后血流感染克拉瓦塔无患子（克拉瓦塔木霉菌）的 18S rRNA 测序和同源性分析及病例报告。

IF 1.8 4区医学

New Microbiologica Pub Date : 2024-01-01

Wei Jia, Guang Chen, Wanxiang Li, Jie Ma, Xue Zhao

引用次数: 0

Neonatal severe COVID-19 infection complicated by Staphilococcus aureus could be misinterpreted as MIS-C?: case report and review of literature. 新生儿严重 COVID-19 感染并发金黄色葡萄球菌可能被误诊为 MIS-C？

IF 1.8 4区医学

New Microbiologica Pub Date : 2024-01-01

Giovanna Stringari, Laura Nai Fovino, Aldo Naselli, Francesca Tota, Michela Capogna, Silvia Graziani, Massimo Soffiati

{"title":"Neonatal severe COVID-19 infection complicated by Staphilococcus aureus could be misinterpreted as MIS-C?: case report and review of literature.","authors":"Giovanna Stringari, Laura Nai Fovino, Aldo Naselli, Francesca Tota, Michela Capogna, Silvia Graziani, Massimo Soffiati","doi":"","DOIUrl":"","url":null,"abstract":"At 23 days of life a neonate presented to the emergency room with crying and decreased oral intake. His parents were positive to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), but he turned out negative. After one week he was admitted to NICU (neonatal intensive care unit) for respiratory failure, and nasopharyngeal swab (PCR test: polymerase chain reaction test) was positive for SARS-CoV-2. On examination the child had fever, tachy-dyspnea, reduced oxygen saturation, tachycardia, abdominal distension and tenderness, irritability and hypertonia. Blood exam showed respiratory acidosis, lymphocytopenia, hypoalbuminemia and coagulopathy; CRP (C reactive protein), procalcitonin, D-dimer, ferritin and NT-proBNP (N-terminal prohormone of brain natriuretic peptide) were elevated. Chest X-ray revealed bilateral interstitial infi ltration and abdomen ultrasound a thin fl uid effusion; echocardiography was normal. SARS-CoV-2 PCR tests on CSF (cerebrospinal fluid) and stool were also positive. He was started on non-invasive intermittent positive pressure respiratory ventilation, treated with antibiotic therapy, methylprednisolone, intravenous immunoglobulins, and antiplatelet therapy. Rapid clinical improvement was seen with remission of fever after eight days. The child complicated with bacterial super-infection presenting as pleural empyema. As presented in our case, it is not always easy to differentiate between severe forms of COVID-19 and MIS-C. Due to the rarity of these presentations in neonates, multicentric collaboration is needed to identify the specifi c characteristics of the two forms, better defi ne diagnostic criteria, and treatment options.","PeriodicalId":54723,"journal":{"name":"New Microbiologica","volume":"46 4","pages":"390-394"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Evaluation of Medicinal Plant Extracts and Antimicrobial Magistrals. 药用植物提取物和抗菌药的比较评估

IF 1.8 4区医学

New Microbiologica Pub Date : 2024-01-01

Hager Muftah, Berrin Özçelik, Ozlem Oyardi, Didem Deliorman Orhan

{"title":"Comparative Evaluation of Medicinal Plant Extracts and Antimicrobial Magistrals.","authors":"Hager Muftah, Berrin Özçelik, Ozlem Oyardi, Didem Deliorman Orhan","doi":"","DOIUrl":"","url":null,"abstract":"The in vitro antimicrobial activity of the active ingredient in antimicrobial magistral drug formulations and plant extracts used in folk medicine were investigated comparatively. Borax, sulfur colloid, hydrogen peroxide, benzoic acid, rivanol, brilliant green and plant extracts as active ingredients, namely: Helianthus tuberosus tuber-H2O (aqueous extract), Cydonia oblonga leaves-H2O, Allium porrum whole plant-H2O, Cistus laurifolius leaves-EtOH, Solanum muricalum-H2O, and Fumaria cilicica leaves-EtOH were studied to determine their antimicrobial activity against different bacteria and fungi (S. pyogenes, S. aureus, S. epidermidis, E. faecalis, K. pneumonia, H. influenza, P. aeruginosa, A. baumannii, E. coli, Candida albicans, C. tropicalis, C. parapsilosis, C. krusei) by using the microdilution method. The active ingredients and plant extracts showed different activities as MIC between 1->128 μg/mL. Brilliant green and rivanol as active ingredients had MIC values of 1 μg/mL against all tested microorganisms. C. oblonga leaves-H2O as well as C. laurifolius leaves-EtOH as plant extracts were indicated as having the highest antimicrobial effect in MIC value of 16 μg/ml against A. baumannii and S. pyogenes, respectively. On the other hand, F. cilicica leaves-EtOH and C. laurifolius leaves-EtOH showed the highest antifungal activity (MIC; 16 μg/mL).","PeriodicalId":54723,"journal":{"name":"New Microbiologica","volume":"46 4","pages":"361-366"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PRESTIGIO RING: "An 80-year-old man living with HIV resistant to all four antiretroviral classes and desiring treatment simplification". prestigio ring："对四种抗逆转录病毒药物均有抗药性并希望简化治疗的 80 岁男性艾滋病毒感染者"。

IF 1.8 4区医学

New Microbiologica Pub Date : 2024-01-01

Maria Mazzitelli, Maurizio Zazzi, Giulia Marchetti, Vincenzo Spagnuolo, Maria Mercedes Santoro, Emanuele Focà, Annamaria Cattelan, Antonella Castagna

引用次数: 0

Research on the Artemia nauplii microorganism compositions based on metagenomics next-generation sequencing. 基于元基因组学新一代测序技术的蒿鱼稚鱼微生物组成研究。

IF 1.8 4区医学

New Microbiologica Pub Date : 2024-01-01

Yang Xu, Dayan Hu, Haihua Cheng, Fei Peng, Qiang Gao

{"title":"Research on the Artemia nauplii microorganism compositions based on metagenomics next-generation sequencing.","authors":"Yang Xu, Dayan Hu, Haihua Cheng, Fei Peng, Qiang Gao","doi":"","DOIUrl":"","url":null,"abstract":"Vibrio species represent the predominant and significant pathogen in global marine fish and shellfish aquaculture. Vibrio species are ubiquitously presented in Artemia cyst hatcheries, and their notable colonization in live prey, particularly Artemia nauplii, leads to the transmission of these pathogens into the digestive system of larval organisms, causing serious problems in Vibriosis in marine aquaculture. To eliminate the Vibriospecies in Artemia nauplii, trichloroisocyanuric acid (TCCA) was used for sterilization of the nauplii. In this study, 3 different concentrations, including 0.5 ppm (FA group), 1.0 ppm (FB group) and 1.5 ppm (FC group) of TCCA were used to treat nauplii for 25 min, and then genomic DNA of the different groups were extracted followed by metagenomic next-generation sequencing (NGS). Bioinformatics analysis was applied and the results indicated that Proteobacter constituted the predominant component within each group at the phylum level, albeit accounting for only 58.68% in the FB group, which was significantly lower than in other groups (>86%). The relative abundance of Vibrio species at genus level showed that when compared with the control group, the FB group (15.8%) was reduced by 25.5%. Beta diversity showed differences between the FB group and the other groups, suggesting that treatment with 1.0ppm TCCA for 25 min would obviously reduce the Vibrio in Artemia nauplii. In conclusion, the Vibrio species were significantly reduced after treatment with TCCA, indicating that TCCA might be an alternative to antibiotics used for live food sterilization in marine aquaculture.","PeriodicalId":54723,"journal":{"name":"New Microbiologica","volume":"46 4","pages":"332-339"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing the antiretroviral treatment focusing on long-term effectiveness and a person-centered approach. Consensus Guidance Using a Delphi Process. 优化抗逆转录病毒治疗，注重长期有效性和以人为本的方法。使用德尔菲程序达成共识指南。

IF 1.8 4区医学

New Microbiologica Pub Date : 2024-01-01

Franco Maggiolo, Sergio Lo Caputo, Stefano Bonora, Marco Borderi, Antonella Cingolani, Gabriella D'Ettorre, Antonio Di Biagio, Simona Di Giambenedetto, Cristina Gervasoni, Giovanni Guaraldi, Paolo Maggi, Lucia Taramasso

{"title":"Optimizing the antiretroviral treatment focusing on long-term effectiveness and a person-centered approach. Consensus Guidance Using a Delphi Process.","authors":"Franco Maggiolo, Sergio Lo Caputo, Stefano Bonora, Marco Borderi, Antonella Cingolani, Gabriella D'Ettorre, Antonio Di Biagio, Simona Di Giambenedetto, Cristina Gervasoni, Giovanni Guaraldi, Paolo Maggi, Lucia Taramasso","doi":"","DOIUrl":"","url":null,"abstract":"Definitive data on the long-term success of the latest antiretroviral therapy (ART) strategies are still lacking. A panel of infectious diseases specialists was convened to develop a consensus on how to tailor and follow ART over time. Panelists used a Delphi technique to develop a list of statements describing preferred management approaches for ART and patient monitoring and quality of life evaluation. Ninety infectious diseases specialists from several Infectious Diseases Centers in Italy participated in the consensus process. A consensus was reached on virological and immunological parameters to use to monitor long-term efficacy of antiretroviral treatment, while there was no consensus on the use of specific inflammation and immune-activation markers in clinical routine. The panel agreed on the need for an antiretroviral treatment with the lowest impact on bone, kidney and cardiovascular toxicity and on the utility of quality-of-life monitoring during the standard follow up of people living with HIV. The consensus statements developed by a panel of infectious diseases specialists may provide guidance to practitioners for a person-centered approach aimed at obtaining long-term virological and clinical success for people living with HIV.","PeriodicalId":54723,"journal":{"name":"New Microbiologica","volume":"46 4","pages":"367-380"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combination effects of baicalin with linezolid against Staphylococcus aureus biofilm-related infections: in vivo animal model. 黄芩苷和利奈唑胺对金黄色葡萄球菌生物膜相关感染的联合作用：体内动物模型。

IF 1.8 4区医学

New Microbiologica Pub Date : 2023-09-01

Zhongye Du, Jiahui Han, Jing Luo, Guan Bi, Tangjuan Liu, Jinliang Kong, Yiqiang Chen

引用次数: 0

Fosfomycin-meropenem synergistic combination against NDM carbapenemase-producing Klebsiella pneumoniae strains. 磷霉素-美罗培南协同组合对抗NDM碳青霉烯酶产生的肺炎克雷伯菌菌株。

IF 1.8 4区医学

New Microbiologica Pub Date : 2023-09-01

Maria Teresa Della Rocca, Giovanni Di Caprio, Francesca Colucci, Filomena Merola, Vittorio Panetta, Emanuele Cordua, Rita Greco

{"title":"Fosfomycin-meropenem synergistic combination against NDM carbapenemase-producing Klebsiella pneumoniae strains.","authors":"Maria Teresa Della Rocca, Giovanni Di Caprio, Francesca Colucci, Filomena Merola, Vittorio Panetta, Emanuele Cordua, Rita Greco","doi":"","DOIUrl":"","url":null,"abstract":"Carbapenemase-producing Enterobacteriaceae (CPE) are an increasing threat to global public health. Treatment of CPE isolates, like New Delhi metallo-β-lactamase (NDM), is limited and often necessitates combination therapies. The aim of this study was to evaluate the synergistic meropenem/fosfomycin combination against K.pneumoniae-producing NDM isolates. Fosfomycin/meropenem, fosfomycin/colistin and meropenem/colistin were tested alone and in combination, using e-test and time-kill assay against 20 clinical carbapenemase-producing K. pneumonia (CPKp NDM) isolates collected from September 2022 to December 2022. K. pneumoniae strains were resistant to meropenem, ceftazidime/avibactam and ceftolozano/tazobactam, 75% and 80% of isolates were susceptible for cefiderocol and for colistin respectively. Fosfomycin/meropenem combination was synergic in 95% (n=19) strains. Fosfomycin/colistin and colistin/meropenem combination showed only 10% synergistic combination strains. In 16 isolates (80%) indifference action for fosfomycin/colistin and colistin/meropenem was reported. For 0.8% of CpKP NDM isolates colistin/meropenem and fosfomycin/colistin combinations found to be antagonistic. In this study, time kill assay showed combination therapies action versus K.pneumoniae metallo-b-lactamase producing (NDM) strains and confirmed the synergistic action of fosfomycin/meropenem combination. In vitro synergy testing should be routinely performed in multidrug resistance infections and combo therapies can be used as a possible alternative in targeted patients with the goal of reducing overall antibiotic costs.","PeriodicalId":54723,"journal":{"name":"New Microbiologica","volume":"46 3","pages":"264-270"},"PeriodicalIF":1.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41174922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Talaromyces marneffei infection in an HIV infected patient with hematological malignancy - first report from Turkey. 一名血液系统恶性肿瘤的HIV感染患者中的Talaromyces marneffei感染——土耳其首次报告。

IF 1.8 4区医学

New Microbiologica Pub Date : 2023-09-01

Ahmet Furkan Kurt, Ebru Cicek, Tamer A M Alhelou, Bilgul Mete, Ridvan Karaali, Mert Ahmet Kuskucu, Zeynep Yazgan, Hatice Yasar Arsu, Sibel Yıldız Kaya, Gokhan Aygun, Fehmi Tabak

{"title":"Talaromyces marneffei infection in an HIV infected patient with hematological malignancy - first report from Turkey.","authors":"Ahmet Furkan Kurt, Ebru Cicek, Tamer A M Alhelou, Bilgul Mete, Ridvan Karaali, Mert Ahmet Kuskucu, Zeynep Yazgan, Hatice Yasar Arsu, Sibel Yıldız Kaya, Gokhan Aygun, Fehmi Tabak","doi":"","DOIUrl":"","url":null,"abstract":"T.marneffei, encountered mostly in Southeast Asia, leads to a systemic infection, especially in immunocompromised individuals such as HIV-infected patients with low CD4 level. A 32-year-old male patient, residing in Hong Kong for the last two years, admitted with fever, cough, weakness, and weight loss. Physical examination revealed bilateral cervical and axillary multiple lymph nodes and hepatosplenomegaly. Screening of the pancytopenic patient revealed HIV infection. Histopathological examination of the cervical lymph node revealed plasmoblastic lymphoma. Blood and urine cultures remained sterile. Antiretroviral therapy was started. Fungal hyphae were detected in Gram staining of hemocultures taken in the third week due to ongoing fever, and antifungal therapy was started empirically. Red pigment around colonies on Sabouraud dextrose agar and microscopic appearance arose suspicion of Talaromyces spp. T.marneffei was identified by ITS 1-4 sequence analysis. Chemotherapy was started when fungemia was controlled. On the fifth day of chemotherapy, the patient's general condition deteriorated, broad-spectrum antibiotics were started and the patient was transferred to ICU. The cultures remained sterile and he expired five days later. In conclusion, although talaromycosis is not endemic in Turkey, it should be considered in patients with travel history to endemic regions and/or an underlying immunosuppressive disease such as HIV infection.","PeriodicalId":54723,"journal":{"name":"New Microbiologica","volume":"46 3","pages":"311-314"},"PeriodicalIF":1.8,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41156629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0