Nutrition Research Reviews最新文献

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Programmes to manage food selectivity in individuals with autism spectrum disorder. 管理自闭症谱系障碍患者食物选择性的计划。
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-02-22 DOI: 10.1017/S0954422424000052
Chiara Breda, Sara Santero, Maria Vittoria Conti, Hellas Cena
{"title":"Programmes to manage food selectivity in individuals with autism spectrum disorder.","authors":"Chiara Breda, Sara Santero, Maria Vittoria Conti, Hellas Cena","doi":"10.1017/S0954422424000052","DOIUrl":"10.1017/S0954422424000052","url":null,"abstract":"<p><p>Autism spectrum disorder (ASD) is a complex group of neurodevelopmental disorders characterised by impaired social communication and restricted interests/repetitive behaviours. In this regard, sensory processing difficulties and delayed oral motor skills often predispose individuals with ASD to food selectivity (FS). It is usually associated with repetitive eating patterns that can lead to multiple malnutrition conditions. The objective of this narrative review is to present an overview about the existing nutritional interventions aiming at promoting a healthy eating pattern and addressing food selectivity among individuals with ASD. Regarding the interventions targeting nutrition education, the majority of the analysed studies failed to demonstrate their effectiveness. On the other hand, many educational interventions involving taste or cooking sessions, as well as behavioural interventions for FS, demonstrated effective results. Moreover, multidisciplinary in tailoring such programmes, including psychology speech therapy and nutritional skills, is acknowledged as a key approach.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"112-125"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of vegetable consumption on risk of gastric cancer: a systematic review and multi-level meta-analysis of prospective studies. 蔬菜摄入对胃癌风险的影响:前瞻性研究的系统回顾和多层次元分析》。
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-02-20 DOI: 10.1017/S0954422424000040
Xiaomin Wu, Guoqiang Qin, Rui Zhang, Yunning Liu, Liling Chen, Jingyang Su, Chao Kong, Zhongze Fang, Jing Wu
{"title":"Effect of vegetable consumption on risk of gastric cancer: a systematic review and multi-level meta-analysis of prospective studies.","authors":"Xiaomin Wu, Guoqiang Qin, Rui Zhang, Yunning Liu, Liling Chen, Jingyang Su, Chao Kong, Zhongze Fang, Jing Wu","doi":"10.1017/S0954422424000040","DOIUrl":"10.1017/S0954422424000040","url":null,"abstract":"<p><p>Vegetables are known to be beneficial to human health, but the association between vegetable consumption and gastric cancer remains uncertain. To synthesise knowledge about the relationship between vegetable group consumption and gastric cancer risk, update present meta-analyses and estimate associations between vegetable consumption and gastric cancer risk based solely on prospective studies, we perform a PRISMA-compliant three-level meta-analysis. Systematic search identified thirteen prospective studies with fifty-two effect sizes that met all inclusion criteria and no exclusion criteria for our meta-analysis. Pooled risk ratios (RRs) showed a positive association between high vegetable consumption and low gastric cancer risk (pooled RR 0·93, 95% confidence interval 0·90-0·97, <i>P</i> = 0·06). In moderator analyses for indicators of gender, region and quantity of vegetable intake, there was no significant difference between subgroups. However, the effect became significant in populations with lower than the minimum risk exposure level (TMREL) of vegetable consumption (<i>P</i> < 0·05). Higher vegetable intake is associated with a decreased risk of gastric cancer. This effect may be limited to specific populations, such as ones with lower vegetable consumption. Evidence from our study has important public health implications for dietary recommendations.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"192-201"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139906893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review of the facilitators and barriers to adoption of biofortified foods and food products. 审查采用生物强化食品和食品的促进因素和障碍。
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-10-08 DOI: 10.1017/S0954422424000258
Samantha L Huey, Saiful Islam, Neel H Mehta, Elsa M Konieczynski, Valerie M Friesen, Jesse T Krisher, Mduduzi N N Mbuya, Eva C Monterrosa, Annette M Nyangaresi, Saurabh Mehta
{"title":"Review of the facilitators and barriers to adoption of biofortified foods and food products.","authors":"Samantha L Huey, Saiful Islam, Neel H Mehta, Elsa M Konieczynski, Valerie M Friesen, Jesse T Krisher, Mduduzi N N Mbuya, Eva C Monterrosa, Annette M Nyangaresi, Saurabh Mehta","doi":"10.1017/S0954422424000258","DOIUrl":"10.1017/S0954422424000258","url":null,"abstract":"<p><p>Biofortification - the process of increasing the concentrations of essential nutrients in staple crops - is a means of addressing the burden of micronutrient deficiencies at a population level via existing food systems, such as smallholder farms. To realise its potential for global impact, we need to understand the factors that are associated with decisions to adopt biofortified crops and food products. We searched the literature to identify adoption determinants, i.e. barriers to (factors negatively associated) or facilitators of (factors positively associated) adoption, of biofortified crops and food products. We found 41 studies reporting facilitator(s) and/or barrier(s) of adoption. We categorised the factors using the Consolidated Framework of Implementation Research 2.0, resulting in a set of factors that enable or constrain adoption of biofortified foods across twenty-four constructs and five domains of this meta-theoretical determinant framework from implementation science. Facilitators of orange sweet potato adoption included knowledge about importance, relative advantage, efficient production and management practices; barriers included lacking timely access to quality vines and market remoteness (28 studies total). Facilitators of vitamin A cassava adoption included awareness of its benefits and access to information; barriers included poor road networks and scarcity of improved technology including inadequate processing/storage facilities (8). Facilitators of high-iron bean adoption included farmers' networking and high farming experience; barriers included low knowledge of bean biofortification (8). Barriers to vitamin A maize adoption included low awareness and concerns regarding yield, texture and aflatoxin contamination (1). These barriers and facilitators may be a starting point for researchers to move towards testing implementation strategies and/or for policymakers to consider before planning scale-up and continuous optimisation of ongoing projects promoting adoption of biofortified crops and food products.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"371-392"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biological properties of vitamin B12. 维生素 B12 的生物特性。
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-10-08 DOI: 10.1017/S0954422424000210
Monika Moravcová, Tomáš Siatka, Lenka Kujovská Krčmová, Kateřina Matoušová, Přemysl Mladěnka
{"title":"Biological properties of vitamin B<sub>12</sub>.","authors":"Monika Moravcová, Tomáš Siatka, Lenka Kujovská Krčmová, Kateřina Matoušová, Přemysl Mladěnka","doi":"10.1017/S0954422424000210","DOIUrl":"10.1017/S0954422424000210","url":null,"abstract":"<p><p>Vitamin B<sub>12</sub>, cobalamin, is indispensable for humans owing to its participation in two biochemical reactions: the conversion of l-methylmalonyl coenzyme A to succinyl coenzyme A, and the formation of methionine by methylation of homocysteine. Eukaryotes, encompassing plants, fungi, animals and humans, do not synthesise vitamin B<sub>12</sub>, in contrast to prokaryotes. Humans must consume it in their diet. The most important sources include meat, milk and dairy products, fish, shellfish and eggs. Due to this, vegetarians are at risk to develop a vitamin B<sub>12</sub> deficiency and it is recommended that they consume fortified food. Vitamin B<sub>12</sub> behaves differently to most vitamins of the B complex in several aspects, e.g. it is more stable, has a very specific mechanism of absorption and is stored in large amounts in the organism. This review summarises all its biological aspects (including its structure and natural sources as well as its stability in food, pharmacokinetics and physiological function) as well as causes, symptoms, diagnosis (with a summary of analytical methods for its measurement), prevention and treatment of its deficiency, and its pharmacological use and potential toxicity.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"338-370"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of coffee-derived chlorogenic acid on cognition: a systematic review and meta-analysis. 咖啡中提取的绿原酸对认知能力的影响:系统综述和荟萃分析。
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-10-15 DOI: 10.1017/S0954422424000209
Karen Johal, Dan J W Jones, Lynne Bell, Julie A Lovegrove, Daniel Joseph Lamport
{"title":"Impact of coffee-derived chlorogenic acid on cognition: a systematic review and meta-analysis.","authors":"Karen Johal, Dan J W Jones, Lynne Bell, Julie A Lovegrove, Daniel Joseph Lamport","doi":"10.1017/S0954422424000209","DOIUrl":"10.1017/S0954422424000209","url":null,"abstract":"<p><p>Coffee drinking has been associated with benefits for various health outcomes, with many attributed to the most prevalent family of polyphenols within coffee, chlorogenic acids (CGA). Whilst reviews of the association between coffee and cognition exist, evidence exploring effects of coffee-specific CGA on cognition has yet to be systematically synthesised. The purpose was to systematically review the current literature investigating the relationship between CGA from coffee and cognitive performance. A further objective was to undertake a meta-analysis of relevant randomised controlled trials (RCT). Observational and intervention studies were included if they considered coffee-based CGA consumption in human participants and applied a standardised measure of cognition. Furthermore, intervention studies were required to define the CGA content and include a control group/placebo. Studies were excluded if they examined CGA alone as an extract or supplement. A search of Scopus, PubMed, Web of Science, ScienceDirect and PsycINFO resulted in including twenty-three papers, six of which were interventions. The evidence from the broader systematic review suggests that CGA from coffee may need to be consumed chronically over a sustained period to produce cognitive benefits. However, the meta-analysis of RCT showed no benefits of coffee CGA intake on cognitive function (<i>d</i> = 0.00, 95% CI -0.05, 0.05). Overall, this review included a limited number of studies, the sample sizes were small, and a wide range of cognitive measures have been utilised. This indicates that further, good-quality interventions and RCT are required to systematically explore the conditions under which coffee CGA may provide benefits for cognitive outcomes.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"393-406"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biological properties of vitamins of the B-complex, part 2 - vitamins B6 and B7 (biotin, vitamin H). 维生素b复合物的生物学特性,第2部分-维生素B6和B7(生物素,维生素H)。
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-05-30 DOI: 10.1017/S0954422425100097
Patrícia Dias, Tomáš Siatka, Marie Vopršalová, Monika Moravcová, Jana Pourová, Nikola Přívratská, Lenka Kujovská Krčmová, Lenka Javorská, Přemysl Mladěnka
{"title":"Biological properties of vitamins of the B-complex, part 2 - vitamins B<sub>6</sub> and B<sub>7</sub> (biotin, vitamin H).","authors":"Patrícia Dias, Tomáš Siatka, Marie Vopršalová, Monika Moravcová, Jana Pourová, Nikola Přívratská, Lenka Kujovská Krčmová, Lenka Javorská, Přemysl Mladěnka","doi":"10.1017/S0954422425100097","DOIUrl":"https://doi.org/10.1017/S0954422425100097","url":null,"abstract":"<p><p>Vitamins B<sub>6</sub> (i.e., pyridoxin and its analogues) and B<sub>7</sub> (i.e., biotin or vitamin H) are essential molecules for many physiological processes. In addition to their well-known involvement in several enzymatic reactions, recent discoveries revealed their participation in other processes, e.g. in gene expression via epigenetic processes, including biotinylation of proteins in the case of biotin. Plants, fungi, archaea and most bacteria synthesize both vitamins, whereas animals and humans lack enzymes for their biosynthesis and depend on their exogenous supply. At least in case of biotin, human gastrointestinal microbiota can likely partly satisfy the need. Both vitamins are water soluble and require a transporter for efficient absorption after oral administration; they can be rapidly excreted, hence being considered largely non-toxic. In addition to physiological and kinetic aspects of vitamins B<sub>6</sub> and biotin, this review, which is based on a search in PubMed up to 2023, covers sources of these vitamins, the impact of food treatment on their content, causes and symptoms of deficiency and specific mutations related to their function. Currently available literature on the analytical determination of these vitamins in biological fluids, possible pharmacological uses, and symptoms of toxicity, although rare, are also included.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"1-107"},"PeriodicalIF":5.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the role of diet in reducing cancer risk in UK firefighters: Mediterranean pattern and the potential for targeted nutritional strategies. 探索饮食在降低英国消防员癌症风险中的作用:地中海模式和有针对性的营养策略的潜力。
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-05-28 DOI: 10.1017/S0954422425100073
Ben Jones, Shelly Coe
{"title":"Exploring the role of diet in reducing cancer risk in UK firefighters: Mediterranean pattern and the potential for targeted nutritional strategies.","authors":"Ben Jones, Shelly Coe","doi":"10.1017/S0954422425100073","DOIUrl":"10.1017/S0954422425100073","url":null,"abstract":"<p><p>Firefighters face significantly elevated cancer risks due to chronic exposure to carcinogenic fire effluents and occupational stressors. In 2022, the World Health Organization classified firefighting as a carcinogenic occupation, linking it to increased incidences of cancers, including mesothelioma, bladder, prostate, colon and melanoma. Drawing on UK-specific data where possible, this narrative review explores how dietary strategies, particularly the Mediterranean diet, may complement existing protective measures in mitigating these risks. It investigates specific food-based nutrients that show promise in addressing risks associated with fire effluent contaminants, examining nutrient-mediated mechanisms and their relevance to firefighter health. The review also highlights the distinct combination of challenges firefighters face in adopting healthier dietary patterns, including disrupted routines, group eating cultures and gaps in nutritional education. While the evidence for firefighter-specific dietary interventions is still emerging, this review highlights the potential of sustainable dietary strategies to significantly reduce cancer risks and improve long-term health outcomes. Finally, it calls for targeted research and interventions to refine these strategies and deliver tangible health benefits for firefighters worldwide.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"1-14"},"PeriodicalIF":5.1,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploiting the vulnerability of SARS-CoV-2 with a partnership of mucosal immune function and nutrition: a narrative review. 利用SARS-CoV-2的脆弱性与粘膜免疫功能和营养的伙伴关系:叙述性综述
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-05-21 DOI: 10.1017/S0954422425100061
Richard J Head, Jonathan D Buckley, Jennifer H Martin
{"title":"Exploiting the vulnerability of SARS-CoV-2 with a partnership of mucosal immune function and nutrition: a narrative review.","authors":"Richard J Head, Jonathan D Buckley, Jennifer H Martin","doi":"10.1017/S0954422425100061","DOIUrl":"10.1017/S0954422425100061","url":null,"abstract":"<p><p>To achieve infectivity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, must first traverse the upper respiratory tract mucosal barrier. Once infection is established, the cascading complexities of the pathophysiology of COVID-19 makes intervention extremely difficult. Thus, enhancing the defensive properties of the mucosal linings of the upper respiratory tract may reduce infection by SARS-CoV-2 and indeed by other viruses such as influenza, which have been responsible for the two major pandemics of the last century. In this review we summarise potential opportunities for foods and nutrients to promote an adequate mucosal immune preparedness with an aim to assist protection against infection by SARS-CoV-2, to maximise the mucosal vaccination (IgA inducing) response to existing systemic vaccines, and to play a role as adjuvants to intranasal vaccines. We identify opportunities for vitamins A and D, zinc, probiotics, bovine colostrum and resistant starch to promote mucosal immunity and enhance the mucosal response to systemic vaccines, and for vitamin A to also improve the mucosal response to intranasal vaccination. It is possible that an entirely different virus may in the future, by way of convergent evolution, utilise a similar upper respiratory tract infection pathway. A greater research focus on mucosal lymphoid immune protection in partnership with nutrition would result in greater preparedness for such an event.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"1-19"},"PeriodicalIF":5.1,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feeding weanling piglets for optimal health and performance: what can we learn from research on complex diets? 饲喂断奶仔猪以获得最佳健康和生产性能:我们可以从复杂日粮研究中学到什么?
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-05-15 DOI: 10.1017/S095442242510005X
Bruno B Carnino, Bruno Bd Muro, Rafaella F Carnevale, Flávio A Coelho, Caio A da Silva, Ines Andretta, Sam Millet, Cesar Ap Garbossa
{"title":"Feeding weanling piglets for optimal health and performance: what can we learn from research on complex diets?","authors":"Bruno B Carnino, Bruno Bd Muro, Rafaella F Carnevale, Flávio A Coelho, Caio A da Silva, Ines Andretta, Sam Millet, Cesar Ap Garbossa","doi":"10.1017/S095442242510005X","DOIUrl":"10.1017/S095442242510005X","url":null,"abstract":"<p><p>Weaning and introduction to a solid diet result in physiological stress in piglets. This can be offset by using complex diets. The terms 'complexity' and 'complex diets' are used in practice and academia but are not precisely defined. The aim of this review was to identify the ingredients in weaner diets, their inclusion levels and how the number of ingredients or complexity of diets influences weaner performance, intestinal and systemic health, environmental sustainability and antibiotic use. Not all diets are formulated equally. Some prioritise meeting the weaner's nutritional needs, while other diets seek to align health promotion and adaptation to the environment. As diet composition is of vital importance for young piglets, the components needed in these complex diets must be defined. Healthy, environmentally adapted pigs have excellent growth performance. We therefore recommend use of a new term, 'gut health supporting diets', to encompass the many concepts associated with diet complexity.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"1-22"},"PeriodicalIF":5.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating the protein transition: why dairy and its matrix matter amid rising plant protein trends. 导航蛋白质转变:为什么乳制品及其基质在植物蛋白上升趋势中很重要。
IF 5.1 2区 医学
Nutrition Research Reviews Pub Date : 2025-04-21 DOI: 10.1017/S0954422425000101
Oliver C Witard, Asli Devrim-Lanpir, Michelle C McKinley, D Ian Givens
{"title":"Navigating the protein transition: why dairy and its matrix matter amid rising plant protein trends.","authors":"Oliver C Witard, Asli Devrim-Lanpir, Michelle C McKinley, D Ian Givens","doi":"10.1017/S0954422425000101","DOIUrl":"10.1017/S0954422425000101","url":null,"abstract":"<p><p>The concept of the protein transition represents a shift from a diet rich in animal proteins to one richer in plant-based alternatives, largely in response to environmental sustainability concerns. However, a simple swap by replacing dairy protein with plant protein will lead to lower protein quality and a lower intake of key micronutrients that sit naturally within the dairy matrix. Owing to antagonistic effects within the plant food matrix, micronutrients in plant sources exhibit lower bioavailability which is not reflected in food composition data or dietary guidelines. The dairy matrix effect includes moderation of blood lipid levels in which calcium plays a key role. Protein recommendations often take a muscle-centric approach. Hence, strategies to increase the anabolic potential of plant proteins have focused on increasing total protein intake to counter the suboptimal amino acid composition relative to dairy protein or leucine fortification. However, emerging evidence indicates a role for nutrient interactions and non-nutrient components (milk exosomes, bioactive peptides) of the dairy matrix in modulating postprandial muscle protein synthesis rates. To ensure the food system transformation is environmentally sustainable and optimal from a nutrition perspective, consideration needs to be given to complementary benefits of different food matrices and the holistic evaluation of foods in the protein transition. This narrative review critically examines the role of dairy in the protein transition, emphasising the importance of the food matrix in nutrient bioavailability and muscle health. By considering both nutritional and sustainability perspectives, we provide a holistic evaluation of dairy's contribution within evolving dietary patterns.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"1-13"},"PeriodicalIF":5.1,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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