Nutrition Research Reviews最新文献

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A Review of the Effect of Iron Supplementation on the Gut Microbiota of Children in Developing Countries and the Impact of Prebiotics 铁补充剂对发展中国家儿童肠道微生物群的影响及益生元影响综述
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-04-08 DOI: 10.1017/s0954422424000118
Ishawu Iddrisu, Andrea Monteagudo-Mera, Carlos Poveda, Muhammed Shahzad, Gemma E. Walton, Simon C. Andrews
{"title":"A Review of the Effect of Iron Supplementation on the Gut Microbiota of Children in Developing Countries and the Impact of Prebiotics","authors":"Ishawu Iddrisu, Andrea Monteagudo-Mera, Carlos Poveda, Muhammed Shahzad, Gemma E. Walton, Simon C. Andrews","doi":"10.1017/s0954422424000118","DOIUrl":"https://doi.org/10.1017/s0954422424000118","url":null,"abstract":"Iron is essential for many physiological functions of the body, and it is required for normal growth and development. Iron deficiency (ID) is the most common form of micronutrient malnutrition and is particularly prevalent in infants and young children in developing countries. Iron supplementation is considered the most effective strategy to combat the risk of ID and ID anaemia (IDA) in infants, although iron supplements cause a range of deleterious gut-related problems in malnourished children. The purpose of this review is to assess the available evidence on the effect of iron supplementation on the gut microbiota during childhood ID and to further assess whether prebiotics offer any benefits for iron supplementation. Prebiotics are well known to improve gut-microbial health in children and recent reports indicate that prebiotics can mitigate the adverse gut-related effects of iron supplementation in ID and IDA children. Thus, provision of prebiotics alongside iron supplements has the potential for an enhanced strategy for combating ID and IDA among children in the developing world. However, further understanding is required before the benefit of such combined treatments of ID in nutritionally-deprived children across populations can be fully confirmed. Such enhanced understanding is of high relevance in resource-poor countries where ID, poor sanitation and hygiene, alongside inadequate access to good drinking water and poor health systems are serious public health concerns.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140592415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges in Identifying Malnutrition in Obesity; An Overview of the State of the Art and Directions for Future Research 识别肥胖症营养不良所面临的挑战;技术现状和未来研究方向概述
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-04-05 DOI: 10.1017/s095442242400012x
Natasha Nalucha Mwala, Jos W. Borkent, Barbara S. van der Meij, Marian A.E. de van der Schueren
{"title":"Challenges in Identifying Malnutrition in Obesity; An Overview of the State of the Art and Directions for Future Research","authors":"Natasha Nalucha Mwala, Jos W. Borkent, Barbara S. van der Meij, Marian A.E. de van der Schueren","doi":"10.1017/s095442242400012x","DOIUrl":"https://doi.org/10.1017/s095442242400012x","url":null,"abstract":"(Protein-energy) malnutrition in individuals living with obesity presents complex diagnostic challenges due to the distinctive physiological characteristics of obesity. This narrative review critically examines the identification of malnutrition within the population with obesity, distinguishing malnutrition from related conditions such as sarcopenic obesity. While noting some shared features, the review highlights key differences between these conditions. The review also highlights the limitations of current malnutrition screening tools, which are not designed for individuals living with obesity. These tools primarily rely on anthropometric measurements, neglecting (among others) nutrient intake assessment, which hinders accurate malnutrition detection. Additionally, this review discusses limitations in existing diagnostic criteria, including the Global Leadership Initiative on Malnutrition (GLIM) criteria, when applied to individuals living with obesity. Challenges include the identification of appropriate cut-off values for phenotypic criteria (unintentional weight loss, low body mass index and muscle mass) and etiological criteria such as reduced food intake and inflammation for the population with obesity. Overall, this review emphasises the need for modified screening tools and diagnostic criteria to recognise and assess malnutrition in obesity, leading to improved clinical outcomes and overall well-being.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140592516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of energy-restricted diets with or without nuts on weight, body composition and glycaemic control in adults: a scoping review. 含或不含坚果的能量限制饮食对成人体重、身体成分和血糖控制的影响:范围综述。
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-02-23 DOI: 10.1017/S0954422424000106
Lauren C Mead, Alison M Hill, Sharayah Carter, Alison M Coates
{"title":"Effects of energy-restricted diets with or without nuts on weight, body composition and glycaemic control in adults: a scoping review.","authors":"Lauren C Mead, Alison M Hill, Sharayah Carter, Alison M Coates","doi":"10.1017/S0954422424000106","DOIUrl":"10.1017/S0954422424000106","url":null,"abstract":"<p><p>Energy-restricted (ER) diets promote weight loss and improve body composition and glycaemic control. Nut consumption also improves these parameters. However, less is known about the combined benefit of these two strategies. This scoping review implemented a systematic search of Medline, Embase and Scopus to identify randomised controlled trials evaluating the effect of ER diets with or without nuts on body mass, body composition and glycaemic control in adults. After reviewing titles and abstracts, twenty-nine full-text articles were screened, resulting in seven studies reported in eight papers that met the inclusion criteria. Energy restriction was achieved by prescribing a set energy target or reducing intake by 1000-4200 kJ from daily energy requirements. Interventions ranged from 4 to 52 weeks in duration and contained 42-84 g/d of almonds, peanuts, pistachios or walnuts. While all studies reported that energy restriction resulted in significant weight loss, the addition of nuts to ER diets demonstrated significantly greater weight loss in only approximately half of the included studies (4/7 studies). There was limited evidence to support additional benefits from nuts for body composition measures or glycaemic control. Although improvements in weight loss and glycaemia were not consistent when nuts were included in ER diets, no study revealed an adverse effect of nut consumption on health outcomes. Future studies could explore the effect of consuming different types and amounts of nuts, combined with various levels of energy restriction on weight, body composition and glycaemic control.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Programmes to manage food selectivity in individuals with autism spectrum disorder. 管理自闭症谱系障碍患者食物选择性的计划。
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-02-22 DOI: 10.1017/S0954422424000052
Chiara Breda, Sara Santero, Maria Vittoria Conti, Hellas Cena
{"title":"Programmes to manage food selectivity in individuals with autism spectrum disorder.","authors":"Chiara Breda, Sara Santero, Maria Vittoria Conti, Hellas Cena","doi":"10.1017/S0954422424000052","DOIUrl":"10.1017/S0954422424000052","url":null,"abstract":"<p><p>Autism spectrum disorder (ASD) is a complex group of neurodevelopmental disorders characterised by impaired social communication and restricted interests/repetitive behaviours. In this regard, sensory processing difficulties and delayed oral motor skills often predispose individuals with ASD to food selectivity (FS). It is usually associated with repetitive eating patterns that can lead to multiple malnutrition conditions. The objective of this narrative review is to present an overview about the existing nutritional interventions aiming at promoting a healthy eating pattern and addressing food selectivity among individuals with ASD. Regarding the interventions targeting nutrition education, the majority of the analysed studies failed to demonstrate their effectiveness. On the other hand, many educational interventions involving taste or cooking sessions, as well as behavioural interventions for FS, demonstrated effective results. Moreover, multidisciplinary in tailoring such programmes, including psychology speech therapy and nutritional skills, is acknowledged as a key approach.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of vegetable consumption on risk of gastric cancer: a systematic review and multi-level meta-analysis of prospective studies. 蔬菜摄入对胃癌风险的影响:前瞻性研究的系统回顾和多层次元分析》。
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-02-20 DOI: 10.1017/S0954422424000040
Xiaomin Wu, Guoqiang Qin, Rui Zhang, Yunning Liu, Liling Chen, Jingyang Su, Chao Kong, Zhongze Fang, Jing Wu
{"title":"Effect of vegetable consumption on risk of gastric cancer: a systematic review and multi-level meta-analysis of prospective studies.","authors":"Xiaomin Wu, Guoqiang Qin, Rui Zhang, Yunning Liu, Liling Chen, Jingyang Su, Chao Kong, Zhongze Fang, Jing Wu","doi":"10.1017/S0954422424000040","DOIUrl":"10.1017/S0954422424000040","url":null,"abstract":"<p><p>Vegetables are known to be beneficial to human health, but the association between vegetable consumption and gastric cancer remains uncertain. To synthesise knowledge about the relationship between vegetable group consumption and gastric cancer risk, update present meta-analyses and estimate associations between vegetable consumption and gastric cancer risk based solely on prospective studies, we perform a PRISMA-compliant three-level meta-analysis. Systematic search identified thirteen prospective studies with fifty-two effect sizes that met all inclusion criteria and no exclusion criteria for our meta-analysis. Pooled risk ratios (RRs) showed a positive association between high vegetable consumption and low gastric cancer risk (pooled RR 0·93, 95% confidence interval 0·90-0·97, <i>P</i> = 0·06). In moderator analyses for indicators of gender, region and quantity of vegetable intake, there was no significant difference between subgroups. However, the effect became significant in populations with lower than the minimum risk exposure level (TMREL) of vegetable consumption (<i>P</i> < 0·05). Higher vegetable intake is associated with a decreased risk of gastric cancer. This effect may be limited to specific populations, such as ones with lower vegetable consumption. Evidence from our study has important public health implications for dietary recommendations.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139906893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing nutritional issues and eating behaviours among university students: a narrative review. 解决大学生的营养问题和饮食行为:叙述性综述。
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-02-15 DOI: 10.1017/S0954422424000088
Noha M Almoraie, Noor M Alothmani, Wajd D Alomari, Amal H Al-Amoudi
{"title":"Addressing nutritional issues and eating behaviours among university students: a narrative review.","authors":"Noha M Almoraie, Noor M Alothmani, Wajd D Alomari, Amal H Al-Amoudi","doi":"10.1017/S0954422424000088","DOIUrl":"10.1017/S0954422424000088","url":null,"abstract":"<p><p>University life is a critical period for establishing healthy eating habits and attitudes. However, university students are at risk of developing poor eating habits due to various factors, including economic conditions, academic stress and lack of information about nutritional concepts. Poor diet quality leads to malnutrition or overnutrition, increasing the risk of preventable diseases. Food environments on university campuses also play a significant role in shaping the dietary habits of students, with the availability of and accessibility to healthy food options being important factors influencing food choices and overall diet quality. Disordered eating habits and body dissatisfaction are prevalent among university students and can lead to eating disorders. Income and living arrangements also influence dietary habits, with low household income and living alone being associated with unhealthy eating habits. This study is a narrative review that aimed to address nutritional issues and eating behaviours, specifically among university students. We investigated the eating behaviours of university students, including their dietary patterns, food choices and food environments. The objective of this review was to provide insights into the nutritional issues and eating behaviours of university students, with the aim of identifying target areas for intervention to improve the overall health and wellbeing among college students. University food environments need to be restructured to promote healthy eating, including the availability, accessibility, affordability and labelling of healthy foods, and policies to limit the availability of unhealthy foods and drinks on campus.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139736720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current perspectives and challenges in the estimation of fruit juice consumption across the lifecycle in Europe. 欧洲果汁生命周期消费估算的现状与挑战。
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-02-15 DOI: 10.1017/S095442242400009X
Janette Walton, Laura Kehoe
{"title":"Current perspectives and challenges in the estimation of fruit juice consumption across the lifecycle in Europe.","authors":"Janette Walton, Laura Kehoe","doi":"10.1017/S095442242400009X","DOIUrl":"10.1017/S095442242400009X","url":null,"abstract":"<p><p>Fruit juice (FJ) is typically low in energy, contains natural sugars, important amounts of micronutrients and is not permitted to have added sugars/sweeteners. However, its role in a healthy diet is under scrutiny partly due to the wider adoption of the definition for free sugars in nutrition policy. This review aimed to identify data on FJ consumption from national food consumption surveys across Europe, to examine current intakes, percent consumers and its contribution to intakes of energy, total sugars, free sugars, vitamin C, folate and potassium. Data were extracted on the population mean intake of FJ and its contribution to nutrient intakes across the lifecycle and crude estimates of population mean intakes across countries were reported for the total population and for consumers only. This review highlighted significant gaps/challenges regarding the availability of country-specific national food consumption surveys across Europe and specifically data on FJ consumption (including complexities surrounding categorisations). Nonetheless, using a comparable/homogenous definition, the mean intake of FJ among consumers was approximately 1 × 150 ml glass/day for adults/older adults, with lower intakes among infants (86 g/d), children (108 g/d) and teenagers (112 g/d). FJ made important contributions to intakes of vitamin C while making little contribution to energy intakes but also contributed 2-14 % of free sugars intake (which may be considered modest compared to other sources). The complexity of collating and interpreting data on FJ intake as elucidated in this review raises questions surrounding the categorisation of FJ in research and presents significant challenges for policymakers with respect to dietary guidance for FJ.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139736721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An overview of nutritional factors in the aetiopathogenesis of myocardial fibrosis in great apes. 类人猿心肌纤维化发病机制中的营养因素概述。
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-02-12 DOI: 10.1017/S0954422424000076
Laurens Van Mulders, Laurent Locquet, Christine Kaandorp, Geert P J Janssens
{"title":"An overview of nutritional factors in the aetiopathogenesis of myocardial fibrosis in great apes.","authors":"Laurens Van Mulders, Laurent Locquet, Christine Kaandorp, Geert P J Janssens","doi":"10.1017/S0954422424000076","DOIUrl":"10.1017/S0954422424000076","url":null,"abstract":"<p><p>The main cause of mortality in great apes in zoological settings is cardiovascular disease (CVD), affecting all four taxa: chimpanzee (<i>Pan troglodytes</i>), bonobo (<i>Pan paniscus</i>), gorilla (<i>Gorilla</i> spp.) and orangutan (<i>Pongo</i> spp.). Myocardial fibrosis, the most typical histological characterisation of CVD in great apes, is non-specific, making it challenging to understand the aetiopathogenesis. A multifactorial origin of disease is assumed whereby many potential causative factors are directly or indirectly related to the diet, which in wild-living great apes mainly consists of high-fibre, low-carbohydrate and very low-sodium components. Diets of great apes housed in zoological settings are often different compared with the situation in the wild. Moreover, low circulating vitamin D levels have recently been recognised in great apes housed in more northern regions. Evaluation of current supplementation guidelines shows that, despite implementation of different dietary strategies, animals stay vitamin D insufficient. Therefore, recent hypotheses designate vitamin D deficiency as a potential underlying factor in the pathogenesis of myocardial fibrosis. The aim of this literature review is to: (i) examine important differences in nutritional factors between zoological and wild great ape populations; (ii) explain the potential detrimental effects of the highlighted dietary discrepancies on cardiovascular function in great apes; and (iii) elucidate specific nutrition-related pathophysiological mechanisms that may underlie the development of myocardial fibrosis. This information may contribute to understanding the aetiopathogenesis of myocardial fibrosis in great apes and pave the way for future clinical studies and a more preventive approach to great ape CVD management.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mollusc and crustacean consumption in the first 1000 days: a scoping review. 头 1,000 天的软体动物和甲壳类动物消费:范围审查。
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-02-12 DOI: 10.1017/S0954422424000064
Brietta M Oaks, Emmanuel A Gyimah, Eliza Kleban, Kathleen Ragsdale, Lora L Iannotti
{"title":"Mollusc and crustacean consumption in the first 1000 days: a scoping review.","authors":"Brietta M Oaks, Emmanuel A Gyimah, Eliza Kleban, Kathleen Ragsdale, Lora L Iannotti","doi":"10.1017/S0954422424000064","DOIUrl":"10.1017/S0954422424000064","url":null,"abstract":"<p><p>Mollusc and crustacean consumption in the first 1000 d may improve maternal and child health by providing essential nutrients. However, in some contexts, molluscs and crustaceans have been associated with allergies and environmental contamination, potentially leading to adverse health and development outcomes. It is unclear whether the health benefits of consuming molluscs and crustaceans, collectively classified as shellfish in nutrition, are outweighed by the potential risks to pregnant women and children. We conducted a scoping review (PROSPERO: CRD42022320454) in PubMed, Scopus and EBSCO Global Health of articles published between January 2000 and March 2022 that assessed shellfish consumption during pregnancy, lactation or childhood (0-2 years) in relation to maternal health, child health or child development. A total of forty-six articles were included in this review. Overall, shellfish consumption was associated with higher biomarkers of environmental contaminants, with mercury being the most studied and having the strongest evidence base. The limited research on nutritional biomarker status shows an association between shellfish consumption and iodine status. Preterm birth was not associated with shellfish consumption, but newborn anthropometry showed mixed results, with several studies reporting lower birth weight with higher shellfish consumption. The few studies that examined child development and maternal health outcomes reported no significant associations. This review revealed trade-off health risks and benefits with inclusion of molluscs and crustaceans in the dietary patterns of mothers and young children. More research is needed to understand how these aquatic animal-source foods may be safely consumed and leveraged for improving human nutrition.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging evidence on selenoneine and its public health relevance in coastal populations: a review and case study of dietary Se among Inuit populations in the Canadian Arctic. 有关硒酮及其在沿海居民中的公共卫生意义的新证据:加拿大北极地区因纽特人膳食中硒含量的回顾与案例研究。
IF 5.7 2区 医学
Nutrition Research Reviews Pub Date : 2024-02-08 DOI: 10.1017/S0954422424000039
Matthew Little, Adel Achouba, Pierre Ayotte, Mélanie Lemire
{"title":"Emerging evidence on selenoneine and its public health relevance in coastal populations: a review and case study of dietary Se among Inuit populations in the Canadian Arctic.","authors":"Matthew Little, Adel Achouba, Pierre Ayotte, Mélanie Lemire","doi":"10.1017/S0954422424000039","DOIUrl":"10.1017/S0954422424000039","url":null,"abstract":"<p><p>Selenium is an essential mineral yet both deficiency and excess are associated with adverse health effects. Dietary intake of Se in humans varies greatly between populations due to food availability, dietary preferences, and local geological and ecosystem processes impacting Se accumulation into agricultural products and animal populations. We argue there is a need to evaluate and reconsider the relevance of public health recommendations on Se given recent evidence, including the metabolic pathways and health implications of Se. This argument is particularly pertinent for Inuit populations in Northern Canada, who often exceed dietary tolerable upper intake levels and exhibit very high whole blood Se concentrations due to their dependence on local country foods high in the newly discovered Se compound, selenoneine. Since selenoneine appears to have lower toxicity compared to other Se species and does not contribute to the circulating pools of Se for selenoprotein synthesis, we argue that total dietary Se or total Se in plasma or whole blood are poor indicators of Se adequacy for human health in these populations. Overall, this review provides an overview of the current evidence of Se speciation, deficiency, adequacy, and excess and implications for human health and dietary recommendations, with particular reference to Inuit populations in the Canadian Arctic and other coastal populations consuming marine foods.</p>","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":null,"pages":null},"PeriodicalIF":5.7,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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