Nutrition and Cancer-An International Journal最新文献_第8页

Adherence to Healthy or Unhealthy Pro-Vegetarian Plant-Based Diets Have Different Impact on Prostate Cancer Severity: Preliminary Findings. 坚持健康或不健康的植物性植物性饮食对前列腺癌症严重程度有不同影响：初步发现。

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2023-12-27 DOI: 10.1080/01635581.2023.2279240

Salvatore Sciacca, Arturo Lo Giudice, Maria Giovanna Asmundo, Sebastiano Cimino, Giuseppe Morgia, Ali A Alshatwi, Andrea Cocci, Giorgio Ivan Russo

{"title":"Adherence to Healthy or Unhealthy Pro-Vegetarian Plant-Based Diets Have Different Impact on Prostate Cancer Severity: Preliminary Findings.","authors":"Salvatore Sciacca, Arturo Lo Giudice, Maria Giovanna Asmundo, Sebastiano Cimino, Giuseppe Morgia, Ali A Alshatwi, Andrea Cocci, Giorgio Ivan Russo","doi":"10.1080/01635581.2023.2279240","DOIUrl":"10.1080/01635581.2023.2279240","url":null,"abstract":"Prostate cancer (PCa) is a prevalent malignancy affecting men worldwide, and plant-based diets have been widely advocated for their health benefits. The aim of this study was to test the association between general, healthy, and unhealthy pro-vegetarian plant-based diets and PCa severity on 118 consecutive patients undergoing prostatectomy in a university hospital in Italy. Food frequency questionnaires were used to calculate scores for dietary patterns. Multivariate logistic regression analyses were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) to test the associations. A general plant-based diet was not associated with cancer severity, while patients reporting a higher adherence to a healthy plant-based diet were less likely to have a more severe PCa (for medium/high vs. low-risk PCa, OR = 0.27, 95% CI: 0.08, 0.88; for high vs. medium/low-risk PCa, OR = 0.09, 95% CI: 0.02, 0.39). Patients resulting in higher adherence to an unhealthy plant-based diet were more likely to be diagnosed with more severe PCa (OR = 6.15, 95% CI: 1.70, 22.24). In conclusion, plant-based dietary patterns may have a different impact on PCa severity depending on the quality of the foods included.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"98-105"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71523403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-Leukemic Attributes of Natural Compounds Targeting Autophagy: A Closer Look into the Molecular Mechanisms. 以自噬为靶点的天然化合物的抗白血病特性：分子机制的近距离观察

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2024-02-01 DOI: 10.1080/01635581.2024.2306682

Sweta Kundu, Sampriti Sarkar, Avik Acharya Chowdhury

{"title":"Anti-Leukemic Attributes of Natural Compounds Targeting Autophagy: A Closer Look into the Molecular Mechanisms.","authors":"Sweta Kundu, Sampriti Sarkar, Avik Acharya Chowdhury","doi":"10.1080/01635581.2024.2306682","DOIUrl":"10.1080/01635581.2024.2306682","url":null,"abstract":"Leukemia is a heterogeneous clonal cancer that affects millions of individuals around the world. Despite substantial breakthroughs in cancer treatment, traditional chemotherapy and radiotherapy remain ineffective, and therapeutic resistance still stands as a big obstacle. As a result, there is an increasing attention being paid currently toward the potency of natural compounds as a complementary or alternative therapy for leukemia. Autophagy, a conserved cellular process where damaged or defective cytosolic components and macromolecules are destroyed and recycled, plays a dual role in promoting or suppressing the continuance of cancer at different junctures of its development. Current studies have reported that autophagy has a cardinal function in the genesis and progression of leukemia, making it a promising target for novel treatments. In this review, we have explored the effectiveness of certain natural compounds, such as curcumin, resveratrol, tanshinone IIA, quercetin, tetrandrine, parthenolide, berberine, pristimerin, and alantolactone, that modulate autophagy and regulate its associated signaling cascades at a molecular level in different types of leukemia. They have been shown to have synergistic effects with conventional chemotherapy, emphasizing their potential as supplementary medicines. However, additional research is required to fully comprehend their mechanisms of action and to maximize their role in clinical perspectives.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"236-251"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Malnutrition in Patients with Hepatocellular Carcinoma: A Comparative Study of GLIM Criteria, NRS2002, and PG-SGA, and Identification of Independent Risk Factors. 肝细胞癌患者营养不良的发生率：GLIM 标准、NRS2002 和 PG-SGA 的比较研究以及独立风险因素的识别。

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2024-02-20 DOI: 10.1080/01635581.2024.2314317

Shengqiang Tan, Jie Jiang, Liulin Qiu, Yaohao Liang, Jianyi Meng, Ning Tan, Bangde Xiang

{"title":"Prevalence of Malnutrition in Patients with Hepatocellular Carcinoma: A Comparative Study of GLIM Criteria, NRS2002, and PG-SGA, and Identification of Independent Risk Factors.","authors":"Shengqiang Tan, Jie Jiang, Liulin Qiu, Yaohao Liang, Jianyi Meng, Ning Tan, Bangde Xiang","doi":"10.1080/01635581.2024.2314317","DOIUrl":"10.1080/01635581.2024.2314317","url":null,"abstract":"Aim: Malnutrition is prevalent in hepatocellular carcinoma (HCC) patients, linked to poor outcomes, necessitating early intervention. This study aimed to investigate malnutrition in HCC patients, assess Nutrition Risk Screening 2002 (NRS-2002) and Patient-Generated Subjective Global Assessment (PG-SGA) vs. Global Leadership Initiative on Malnutrition (GLIM) criteria, and identify independent risk factors.Method: A cross-sectional retrospective study was conducted on 207 patients with HCC. Nutritional screening/assessment results and blood samples were collected within 72 h of admission. This study assessed the prevalence of malnutrition using the NRS-2002 and PG-SGA and retrospectively using the GLIM criteria. The performance of the screening tools was evaluated using kappa (K) values. Logistic regression analyses were performed to determine whether laboratory parameters were associated with malnutrition as identified by the GLIM criteria.Results: Of the participants, 30.4% were at risk of malnutrition according to NRS-2002. The agreement between the NRS-2002 and GLIM criteria was substantial. The GLIM criteria and PG-SGA diagnosed malnutrition in 43 and 54.6% of the participants, respectively. Age, anemia, and ascites correlated with malnutrition in regression.Conclusion: The GLIM criteria, along with NRS-2002 and PG-SGA, aid in diagnosing malnutrition in HCC patients. Recognizing risk factors improves accuracy, enabling timely interventions for better outcomes.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"335-344"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139914065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical, Functional, and Nutritional Efficacy of a Glutamine-Enriched Oligomeric Diet in Patients with Rectal Cancer. 富含谷氨酰胺的低聚物饮食对直肠癌患者的临床、功能和营养效果。

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2023-12-27 DOI: 10.1080/01635581.2023.2286698

Johanna Del Carmen Peña Vivas, Andrea Carolina Orduz Arena, Ana Alonso García, Carlos Fernando Carrascal Gordillo, Rocío Martínez Gutiérrez, Cristina Rodríguez-Acosta Caballero, Ignacio Fernández Freije, Ana Belén Paino Martínez, Tamara Belloso Cuesta, Germán Juan Rijo, Alicia Calleja Fernández

{"title":"Clinical, Functional, and Nutritional Efficacy of a Glutamine-Enriched Oligomeric Diet in Patients with Rectal Cancer.","authors":"Johanna Del Carmen Peña Vivas, Andrea Carolina Orduz Arena, Ana Alonso García, Carlos Fernando Carrascal Gordillo, Rocío Martínez Gutiérrez, Cristina Rodríguez-Acosta Caballero, Ignacio Fernández Freije, Ana Belén Paino Martínez, Tamara Belloso Cuesta, Germán Juan Rijo, Alicia Calleja Fernández","doi":"10.1080/01635581.2023.2286698","DOIUrl":"10.1080/01635581.2023.2286698","url":null,"abstract":"Aims: This work aims to evaluate the efficacy of nutritional supplementation with a glutamine-enriched oligomeric diet (GEOD) compared to a standard polymeric diet (SPD) in terms of oncology treatment-related diarrhea (OTRD) (frequency and consistency of stools), gastrointestinal toxicity, and functional and nutritional progress.Methods: This prospective cohort study compared two groups of patients with rectal cancer in treatment with neoadjuvant chemotherapy and radiotherapy who were at risk of malnutrition. Patients were randomized to receive either 400 ml of GEOD or of SPD from the start of radiotherapy to 30 days after its completion.Results: Eighty patients were recruited, 40 per arm. The GEOD arm had improved stool consistency and a greater reduction in the number of stools compared to the SPD arm (p < 0.001). The relative risk (RR) of developing diarrhea in the GEOD arm was 0.059 (95% CI 0.015-0.229). There was a reduced risk of developing intestinal mucositis in the GEOD arm compared to the SPD arm [RR 0.202 (95% CI 0.102 - 0.399)]. The GEOD arm had greater improvements in functional and nutritional status (p < 0.001).Conclusions: GEOD had a protective effect in terms of the development of gastrointestinal toxicity associated with chemotherapy and radiotherapy treatment in patients with rectal cancer.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"128-136"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138296543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on Meta-Analysis Conducted by Li et al. 对 Li 等人所做 Meta 分析的评论

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2024-03-18 DOI: 10.1080/01635581.2024.2331276

Theodore M Brasky, Jill T Brasky

引用次数: 0

Dietary Branched Chain Amino Acids Association with Cancer and Mortality: A Systematic Review and Meta-Analysis of Observational Studies. 膳食支链氨基酸与癌症和死亡率的关系：观察性研究的系统回顾和元分析》。

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2024-01-18 DOI: 10.1080/01635581.2023.2292820

Mahdieh Tabesh, Farshad Teymoori, Hamid Ahmadirad, Parvin Mirmiran, Seyedeh Tayebeh Rahideh

{"title":"Dietary Branched Chain Amino Acids Association with Cancer and Mortality: A Systematic Review and Meta-Analysis of Observational Studies.","authors":"Mahdieh Tabesh, Farshad Teymoori, Hamid Ahmadirad, Parvin Mirmiran, Seyedeh Tayebeh Rahideh","doi":"10.1080/01635581.2023.2292820","DOIUrl":"10.1080/01635581.2023.2292820","url":null,"abstract":"The present study aimed to investigate the association of dietary branched-chain amino acids (BCAAs) and its components with cancer, cancer mortality, and all-cause mortality in a meta-analysis of observational studies. A comprehensive search was conducted between electronic databases (PubMed, Scopus, and Web of Science) until September 2022. Odds ratios (OR), hazard ratios (HR), and relative risks (RR) were extracted. Eight articles (six studies on breast cancer (BC) and digestive cancers risk, and three studies on both BC and digestive cancers mortality, and all-cause mortality) were included. The present study showed no statistically significant association between dietary BCAAs and its components with BC and digestive cancers (RRBCAA: 0.87, 95% CI: 0.68-1.10, RRLeucine: 0.74, 95% CI: 0.52-1.04, RRIsoleucine: 0.98, 95% CI: 0.93-1.04, RRValine: 0.76, 95% CI: 0.55-1.05). Also, no statistically significant relationship between dietary BCAAs and its components with both BC and digestive cancers mortality (RRBCAA: 0.95, 95% CI: 0.68-1.33, RRLeucine: 0.95, 95% CI: 0.79-1.15, RRIsoleucine: 0.95, 95% CI: 0.79-1.14, RRValine: 1.01, 95% CI: 0.84-1.21) and all-cause mortality (RRBCAA: 0.98, 95% CI: 0.73-1.32, RRLeucine: 1.02, 95% CI: 0.81-1.29, RRIsoleucine: 0.96, 95% CI: 0.73-1.27, RRValine: 1.02, 95% CI: 0.79-1.32) were observed. Our findings showed no significant association between dietary BCAAs and its components with BC and digestive cancers, BC and digestive cancers mortality, and all-cause mortality.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"160-174"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrition Risk Screening 2002 for Adult Cancer Patients: A Systematic Review and Meta-Analysis. 2002 年成人癌症患者营养风险筛查：系统回顾与元分析》。

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2024-05-17 DOI: 10.1080/01635581.2024.2352901

Pengpeng Wang, Yanmei Tan, Kim Lam Soh, Kim Geok Soh, Chuanyi Ning, Li Xue, Yunhong Lu, Jie Yang

{"title":"Nutrition Risk Screening 2002 for Adult Cancer Patients: A Systematic Review and Meta-Analysis.","authors":"Pengpeng Wang, Yanmei Tan, Kim Lam Soh, Kim Geok Soh, Chuanyi Ning, Li Xue, Yunhong Lu, Jie Yang","doi":"10.1080/01635581.2024.2352901","DOIUrl":"10.1080/01635581.2024.2352901","url":null,"abstract":"It is critical to screen and assess malnutrition in cancer patients early. However, there is no uniform standard for nutritional risk screening and malnutrition assessment. We aimed to analyze the effects of the Nutrition Risk Screening 2002 (NRS2002) in screening for nutritional risk among adult cancer patients, using the Patient-Generated Subjective Global Assessment (PG-SGA) as the reference standard. A systematic search was performed using PubMed, Embase, Web of Science, the Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, and China Science and Technology Journal Database (VIP). Studies comparing NRS2002 with PG-SGA in adult cancer patients were included. To assess the quality of the included studies, the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) was used. The combined sensitivity, specificity, diagnostic odds ratio (DOR), and the area under the receiver-operating characteristic curve (AUC) were calculated. In addition, sensitivity, subgroup, and publication bias analyses were performed. Thirteen articles involving 3,373 participants were included. The combined sensitivity, specificity, DOR, and AUC were 0.62 (95% CI, 0.60-0.64), 0.86 (95% CI, 0.84-0.88), 11.23 (95% CI, 8.26-15.27), and 0.85 (95% CI, 0.82-0.88), respectively. For adult cancer patients, NRS2002 has moderate sensitivity, high specificity, and high AUC in screening for nutritional risk.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"573-583"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nicotinamide N-Methyltransferase (NNMT) is Involved in Gastric Adenocarcinoma Immune Infiltration by Driving Amino Acid Metabolism. 烟酰胺 N-甲基转移酶（NNMT）通过促进氨基酸代谢参与胃腺癌的免疫渗透

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2024-06-10 DOI: 10.1080/01635581.2024.2359741

Jianyong Lu, Wenliang Gui, Shen Tang, Qianqian Shi, Xinhang Wang, Liyuan Huang, Yinghui Shen, Shuting Yang, Junni Xiang, Jianglang Yuan, Jiao Mo, Xingxing Kong, Mingwei Huang, Xiyi Li, Cailing Lu

{"title":"Nicotinamide N-Methyltransferase (NNMT) is Involved in Gastric Adenocarcinoma Immune Infiltration by Driving Amino Acid Metabolism.","authors":"Jianyong Lu, Wenliang Gui, Shen Tang, Qianqian Shi, Xinhang Wang, Liyuan Huang, Yinghui Shen, Shuting Yang, Junni Xiang, Jianglang Yuan, Jiao Mo, Xingxing Kong, Mingwei Huang, Xiyi Li, Cailing Lu","doi":"10.1080/01635581.2024.2359741","DOIUrl":"10.1080/01635581.2024.2359741","url":null,"abstract":"Objectives: This study investigates the role of Nicotinamide N-methyltransferase (NNMT) in immune infiltration modulation through amino acid metabolism in gastric adenocarcinoma (STAD). Methods: Utilizing data from The Cancer Genome Atlas (TCGA) and validated with clinical samples, we analyzed NNMT expression and its prognostic implications in STAD. Differential amino acid profiles between cancerous and adjacent normal tissues were assessed, along with their associations with NNMT. Results: NNMT exhibits heightened expression in STAD cancer tissues, positively correlating with tumor immune infiltration. Additionally, twenty-eight amino acids display differential expression in gastric tissue, with their metabolic enzymes showing connections to NNMT. Conclusions: Elevated NNMT expression in STAD tissues potentially influences amino acid metabolism, thereby affecting immune infiltration dynamics and tumorigenesis in gastric adenocarcinoma.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"745-759"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sarcopenia as a Predictive Factor for Carboplatin Toxicity in Patients with Advanced Non-Small Cell Lung Cancer. 肉骨减少症是晚期非小细胞肺癌患者卡铂毒性的预测因素。

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2024-07-26 DOI: 10.1080/01635581.2024.2382390

Jenny G Turcott, Sayako M Miyagui, Salvador Gutiérrez Torres, Daniela Cárdenas-Fernández, Enrique Caballé-Perez, Eduardo Rios-Garcia, Andrés F Cardona, Christian Rolfo, Oscar Arrieta

{"title":"Sarcopenia as a Predictive Factor for Carboplatin Toxicity in Patients with Advanced Non-Small Cell Lung Cancer.","authors":"Jenny G Turcott, Sayako M Miyagui, Salvador Gutiérrez Torres, Daniela Cárdenas-Fernández, Enrique Caballé-Perez, Eduardo Rios-Garcia, Andrés F Cardona, Christian Rolfo, Oscar Arrieta","doi":"10.1080/01635581.2024.2382390","DOIUrl":"10.1080/01635581.2024.2382390","url":null,"abstract":"Sarcopenia in cancer patients often negatively impacts various outcomes. Carboplatin, a first-line chemotherapy for non-small cell lung cancer (NSCLC), is dosed based on body weight, which doesn't account for sarcopenia. This study evaluated the association between sarcopenia and carboplatin-related toxicity in NSCLC patients. Patients with locally advanced or metastatic NSCLC treated with carboplatin were included. Toxicity events during the first two cycles of treatment were recorded. Sarcopenia was assessed using pretreatment computed tomography scans analyzed with Slice-O-Matic V4.2 software, defining sarcopenia as a skeletal muscle index (SMI) of <52.4 cm2/m2 for men and <38.5 cm2/m2 for women. Among 146 patients, 52% had sarcopenia. Hematological toxicity occurred in 71.2% of all patients and 77.6% of those with sarcopenia. The fat-free mass index (FFMI) was independently associated with hematological toxicity and dose-limiting toxicity (DLT), which was observed in 55.5% of patients. Sarcopenia significantly correlates with hematological toxicity and DLT during carboplatin treatment in NSCLC patients. Given its prevalence and noninvasive detection, further research is needed to understand its impact on treatment outcomes.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"985-993"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141768017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Avocado and Guacamole Consumption and Colorectal Cancer Risk: The Multiethnic Cohort Study. 牛油果和鳄梨酱的食用量与结直肠癌风险：多种族队列研究。

IF 2 4区医学

Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2024-02-29 DOI: 10.1080/01635581.2024.2320950

Feon W Cheng, Song-Yi Park, Christopher A Haiman, Lynne R Wilkens, Loïc Le Marchand, Nikki A Ford

{"title":"Avocado and Guacamole Consumption and Colorectal Cancer Risk: The Multiethnic Cohort Study.","authors":"Feon W Cheng, Song-Yi Park, Christopher A Haiman, Lynne R Wilkens, Loïc Le Marchand, Nikki A Ford","doi":"10.1080/01635581.2024.2320950","DOIUrl":"10.1080/01635581.2024.2320950","url":null,"abstract":"Dietary fiber and phytonutrients can protect against colorectal cancer, yet their consumption is low in the US. Avocados are a potential source of these beneficial nutrients. Therefore, this study aimed to examine the relationship between avocados/guacamole consumption and colorectal cancer risk in the Multiethnic Cohort Study. We assessed avocados/guacamole consumption by using a food frequency questionnaire. We classified participants into three consumer groups: <1 serving/month, 1-3 servings/month, and ≥1 serving/week with one serving defined as ½ avocado or ½ cup. Colorectal cancer cases were ascertained through the Surveillance, Epidemiology and End Results Program cancer registries. Cox proportional hazards models of colorectal cancer were used to calculate hazard ratios and 95% confidence intervals across avocados/guacamole intake groups in each sex overall and by anatomic subsite (i.e., right colon, left colon, and rectum) and race and ethnicity. Of 192,651 eligible participants, 62.8% reported consuming <1 serving/month avocados/guacamole, 26.7% reported 1-3 servings/month, and 10.5% reported ≥1 serving/week. When adjusted for relevant covariates, there was no significant association with incident colorectal cancer overall, for subsites, or within racial and ethnic subgroups (all p for trend ≥ 0.06). In this large prospective cohort study, we did not find that consumption of avocados/guacamole was associated with colorectal cancer risk.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":"76 4","pages":"372-378"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10949089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0