Pace-Pacing and Clinical Electrophysiology最新文献_第2页

Painful Left Bundle Branch Block Syndrome: A Systematic Review of Treatment Strategies in Case Reports.

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-06 DOI: 10.1111/pace.15156

Rodrigo Rufino Pereira Silva, Carolina Jerônimo Magalhães, Caio Correia da Silva, José Nunes de Alencar Neto

{"title":"Painful Left Bundle Branch Block Syndrome: A Systematic Review of Treatment Strategies in Case Reports.","authors":"Rodrigo Rufino Pereira Silva, Carolina Jerônimo Magalhães, Caio Correia da Silva, José Nunes de Alencar Neto","doi":"10.1111/pace.15156","DOIUrl":"https://doi.org/10.1111/pace.15156","url":null,"abstract":"Background: Painful left bundle branch block (PLBBB) syndrome remains a poorly understood cardiac anomaly. This systematic review consolidates case report evidence to elucidate effective management strategies and patient outcomes.Methods: Databases including PubMed, Scopus, Web of Science, and Scielo were searched without restrictions on language or publication date. Following PRISMA guidelines, 128 articles were identified, with 31 meeting inclusion criteria. Data were extracted on patient demographics, clinical presentation, treatment regimens, and outcomes using Microsoft Excel and assessed for bias with the Joanna Briggs Institute's tool.Results: The analysis included 45 patients with a mean age of 55.46 ± 12.23. Predominantly, LBBB episodes occurred during exercise (73.3%). Initial treatments comprised beta-blockers/calcium channel blockers (55.56%), pacemaker implantation (13.3%), antianginal medications (13.3%), and other modalities (17.7%). Refractoriness to initial treatment was observed in 66.7% of patients, with subsequent pacemaker implantation resolving symptoms in most cases. An overall satisfactory response was seen in 73.3% of patients post-treatment adjustments.Conclusions: The diverse approaches in treatment highlight the necessity for tailored therapeutic strategies. While pacemakers have demonstrated efficacy in controlling symptoms in several reported cases, it is essential to recognize the complex nature of this intervention. Pacemaker implantation, being a surgical procedure, carries long-lasting implications for patients. Hence, the continuation of pharmacological treatments might still be preferable until more definitive research is available. This review emphasizes the urgent need for further research to establish evidence-based guidelines, particularly concerning the selection of first line of treatment, to optimize outcomes for PLBBB syndrome.","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Associated With LVEF Improvement Following Arrhythmia Management in Patients With Tachycardiomyopathy.

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-06 DOI: 10.1111/pace.15157

Naoya Kataoka, Teruhiko Imamura

引用次数: 0

Progressed Atrioventricular Block in Immune Checkpoint Inhibitor Induced Myocarditis: A Case Report.

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-06 DOI: 10.1111/pace.15155

Dongmei Xie, Ting Yan, Xin Zhang, Xingbin Liu

引用次数: 0

Topological Distribution of KCNH2 Variants and Genotype-Phenotype Relationship in Patients With Long QT Syndrome.

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-06 DOI: 10.1111/pace.15145

Hongyu Liu, Zhenhong Jiang, Yang Shen, Ying Shao, Yuhao Su, Daowu Wang, Ramon Brugada, Kui Hong

{"title":"Topological Distribution of KCNH2 Variants and Genotype-Phenotype Relationship in Patients With Long QT Syndrome.","authors":"Hongyu Liu, Zhenhong Jiang, Yang Shen, Ying Shao, Yuhao Su, Daowu Wang, Ramon Brugada, Kui Hong","doi":"10.1111/pace.15145","DOIUrl":"https://doi.org/10.1111/pace.15145","url":null,"abstract":"Aims: The aim of this study was to investigate the topological distribution of single nucleotide variants (SNVs) in the KCNH2 gene from patients with type 2 long QT syndrome (LQT2) and to explore the genotype-phenotype relationships.Methods: Information on KCNH2 variants in LQT2 patients was retrospectively obtained from the HGMD, ClinVar, and PubMed databases through October 2022. Pathogenicity of SNV was classified according to the American College of Medical Genetics and Genomics (ACMG) guidelines. Unpaired t-tests and Fisher's exacts were used to analyze the SNV distributions across structural and functional domains, and their correlation with clinical phenotypes.Results: A total of 2826 variants were obtained; 2152 were SNVs, 1328 of which were nonsynonymous SNVs (nsSNVs) associated with LQT2. Enrichment analysis revealed that 602 pathogenic (P) and likely pathogenic (LP) nsSNVs were significantly enriched at S5, H5, S6, Extra3, and Extra4. In addition, 759 nsSNVs and 289 P/LP nsSNVs within function domain were enriched at the per-arnt-sim (PAS) and selectivity filter (SF) functional domain. Clinical data revealed that patients with nsSNVs enriched at the N-terminal, S5-H5-S6 region and PAS domain were associated with an increased risk of syncope. Moreover, nsSNVs located at the N-terminal, S5-H5-S6 region, and PAS, SF domains were associated with an increased risk of life-threatening cardiac events, including Torsade de Pointes (TdP) and sudden cardiac death (SCD), and were predominantly female.Conclusion: KCNH2 nsSNVs located at the N-terminal, S5-H5-S6 region, and the PAS and SF functional domains are associated with an increased risk of life-threatening cardiac events in LQT2 patients.","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporary Transvenous Pacing Performed in the Intensive Care Unit or in the Catheterization Laboratory. 临时经静脉起搏在重症监护病房或导管实验室进行。

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-01 Epub Date: 2025-01-10 DOI: 10.1111/pace.15140

Julie Bastide, Francis Bessière, Antoine Delinière, Thomas Bochaton, Kévin Gardey, Arnaud Dulac, Christelle Haddad, Cyril Prieur, Danka Tomasevic, Gilles Rioufol, Eric Bonnefoy-Cudraz, Geoffroy Ditac

{"title":"Temporary Transvenous Pacing Performed in the Intensive Care Unit or in the Catheterization Laboratory.","authors":"Julie Bastide, Francis Bessière, Antoine Delinière, Thomas Bochaton, Kévin Gardey, Arnaud Dulac, Christelle Haddad, Cyril Prieur, Danka Tomasevic, Gilles Rioufol, Eric Bonnefoy-Cudraz, Geoffroy Ditac","doi":"10.1111/pace.15140","DOIUrl":"10.1111/pace.15140","url":null,"abstract":"Background: Temporary transvenous pacing (TTP) is a common procedure, predominantly performed in the catheterization laboratory (cath lab) because of presumed lower complication rate. This study aims to evaluate the efficacy and safety of TTP placement in the ICU compared to TTP placement in the cath lab.Methods: This retrospective, real-life study included all patients requiring TTP in a tertiary care ICU between 2019 and 2022. Patients' characteristics, TTP-related data, outcomes, and complications were compared between groups (ICU vs. cath lab).Results: Data from 193 patients receiving TTP were analyzed; 68.4% received TTP in the ICU and 31.6% in the cath lab. The main indication was atrioventricular block in 154 patients (79.8%). The operator was less frequently an interventional cardiologist in the ICU (12.1%) compared to the cath lab (100%, p < 0.001). TTP in the ICU was more frequently performed using a jugular access (72.0% vs. 1.6%), a right-sided laterality (88.7% vs. 43.6%), and a balloon-tipped catheter (100% vs. 0%, p < 0.001 for all comparisons). Success was 100% in both groups. The overall complication rate was 16.6%, with no significant difference between both groups (14.4% ICU vs. 21.3% cath lab, p = 0.13), but a tendency toward higher complications in the cath lab group (especially tamponade, lead displacement, and CIED infection).Conclusion: In a daily clinical scenario, TTP placement appears as safe in the ICU than in the cath lab, regardless of the operator's level of expertise when performed in accordance with best practices. Nevertheless, TTP complications remain high, and alternatives should be used whenever possible.","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"262-269"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonocclusive Ablation Technique Using a Novel Cryoballoon for Failed Left Superior Pulmonary Vein Isolation Despite Complete Occlusion. 新型低温球囊非闭塞消融技术在完全闭塞的情况下仍无法隔离左上肺静脉。

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-01 Epub Date: 2025-01-05 DOI: 10.1111/pace.15136

Kazuya Murata, Yasuteru Yamauchi, Yumi Yasui, Atsuhito Oda, Hirofumi Arai, Yuichiro Sagawa, Hideki Arima, Manabu Kurabayashi, Shinsuke Miyazaki, Tetsuo Sasano

{"title":"Nonocclusive Ablation Technique Using a Novel Cryoballoon for Failed Left Superior Pulmonary Vein Isolation Despite Complete Occlusion.","authors":"Kazuya Murata, Yasuteru Yamauchi, Yumi Yasui, Atsuhito Oda, Hirofumi Arai, Yuichiro Sagawa, Hideki Arima, Manabu Kurabayashi, Shinsuke Miyazaki, Tetsuo Sasano","doi":"10.1111/pace.15136","DOIUrl":"10.1111/pace.15136","url":null,"abstract":"Background: An indicator of successful cryoballoon (CB)-assisted pulmonary vein (PV) isolation is complete PV occlusion. However, CBs may exhibit a weaker freezing effect on the equatorial plane. This study investigates the predictors of failed left superior PV (LSPV) isolation despite complete occlusion with novel CBs.Methods: This retrospective analysis enrolled 300 consecutive patients who underwent first-time ablation with POLARx or POLARxFIT between November 2021 and October 2023. Of the total, complete occlusion of the LSPV was achieved in 200 patients. Patients in whom LSPV isolation was achieved with additional nonocclusive freezing of the LSPV roof due to nonisolation of LSPV despite complete occlusion (Group A) were compared with those in whom isolation was achieved with complete PV occlusion alone (Group B).Results: Group A had a larger LSPV diameter (21.5 ± 4.6 mm vs. 18.8 ± 3.3 mm, p = 0.052), larger left atrial volume on CT (142.3 ± 47.8 cc vs. 117.8 ± 39.0 cc, p = 0.028), higher nadir temperature (-54.1 ± 5.1°C vs. -60.2 ± 4.4°C, p < 0.001), and smaller northern latitude of the balloon contact site on the LSPV roof side (20.9° ± 3.8° vs. 38.9° ± 6.7°, p < 0.001) compared with Group B. A 27.5° north latitude was observed in most of Group A (sensitivity, 100%; specificity, 96%).Conclusions: Adequate contact positioning of the northern hemisphere to the LSPV is critical for effective isolation, particularly when isolation is challenging despite complete occlusion. In such cases, nonocclusive cryoablation against the LSPV roof might be effective.","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"192-201"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pacing and Ablation Technique Using Microelectrode for Pulmonary Vein Isolation Using a Local Impedance-Guided Catheter.

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-01 Epub Date: 2025-01-27 DOI: 10.1111/pace.15144

Hitoshi Mori, Hidehira Fukaya, Kazuhisa Matsumoto, Masataka Narita, Tsukasa Naganuma, Wataru Sasaki, Naomichi Tanaka, Daisuke Kawano, Yoshifumi Ikeda, Kazuo Matsumoto, Ritsushi Kato

{"title":"Pacing and Ablation Technique Using Microelectrode for Pulmonary Vein Isolation Using a Local Impedance-Guided Catheter.","authors":"Hitoshi Mori, Hidehira Fukaya, Kazuhisa Matsumoto, Masataka Narita, Tsukasa Naganuma, Wataru Sasaki, Naomichi Tanaka, Daisuke Kawano, Yoshifumi Ikeda, Kazuo Matsumoto, Ritsushi Kato","doi":"10.1111/pace.15144","DOIUrl":"10.1111/pace.15144","url":null,"abstract":"Background: The IntellaNav MiFi OI catheter (MiFi) is equipped with a sensor for local impedance (LI) monitoring and three mini-electrodes. In this study, we investigated the target LI values for a successful pulmonary vein isolation (PVI) under the pacing and ablation technique using the MiFi catheter.Methods: Twenty-seven patients underwent PVI using the MiFi catheter under mini electrode pacing from the MiFi catheter. The local impedance (LI) changes, generator impedance (GI) changes, and the time to capture loss were evaluated.Results: First-pass isolations were obtained in 15 patients (57.7 %) for right PVs and in 22 patients (84.6 %) for left PVs. At gap sites, the impedance decrease was smaller than at non-gap sites (non-gap sites vs. gap sites; LI drop, 23.2 [±10.3] vs. 15.6 [±7.7] Ω, p < 0.0001; GI drop, 4.8 [±4.1] vs. 2.7 [3.9] Ω, p = 0.0026; %LI drop, -19.3 [±7.4] vs. -13.1 [±6.1] %, p < 0.0001; % GI drop, -5.1 [±4.2] vs. -2.9 [±4.2] %, p = 0.0020), suggesting that changes in impedance could be useful for predicting gaps. The cutoff values for predicting no gaps were identified as 15.0 Ω for the LI drop and -13.74% for the %LI drop.Conclusion: The LI showed greater changes than the GI and was also useful for predicting gaps. The cutoff values of 15.0 Ω for the LI drop and -13.74% for the %LI drop could predict conduction gaps. Under the monitoring of the LI, the pacing and ablation technique proved useful for PVI, even though the MiFi catheter does not have a CF sensor or ablation indices.","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"216-223"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conduction System Pacing Following a Double Switch Operation for Congenitally Corrected Transposition of the Great Arteries. 先天性大动脉转位双开关手术后的传导系统起搏。

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-01 Epub Date: 2024-12-24 DOI: 10.1111/pace.15122

William Regan, Eric Rosenthal, John-Ross Clarke, Harith Alam, Tom Wong

引用次数: 0

Tachycardiomyopathy Treated With Ablation by Using 3D Mapping System in a Patient With Friedreich Ataxia. 三维定位系统消融治疗弗里德赖希共济失调患者的心动过速。

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-01 Epub Date: 2024-12-24 DOI: 10.1111/pace.15125

Mert İlker Hayıroğlu, Koray Kalenderoğlu, Kadir Gürkan

引用次数: 0

Trends and Disparities in Atrial Fibrillation and Stroke Related Mortality in the United States from 1999 to 2020. 1999 年至 2020 年美国心房颤动和中风相关死亡率的趋势和差异。

IF 1.7 4区医学

Pace-Pacing and Clinical Electrophysiology Pub Date : 2025-02-01 Epub Date: 2024-11-27 DOI: 10.1111/pace.15111

Vardhmaan Jain, Birju Rao, Eduardo Quintero, Anand D Shah, Faisal M Merchant, Mikhael F El-Chami, Neal Bhatia, Stacy Westerman, Michael S Lloyd

引用次数: 0