Margarida Pujol-Lopez, Mariona Regany-Closa, Berta Pellicer-Sendra, Marta Martínez-Pérez, Rubén Molero, Freddy R Graterol, María S Guillem, Eduard Guasch, José M Tolosana, Lluís Mont
{"title":"Electrocardiographic Imaging: A New Tool to Ensure Cardiac Resynchronization During Left Bundle Branch Pacing Implant.","authors":"Margarida Pujol-Lopez, Mariona Regany-Closa, Berta Pellicer-Sendra, Marta Martínez-Pérez, Rubén Molero, Freddy R Graterol, María S Guillem, Eduard Guasch, José M Tolosana, Lluís Mont","doi":"10.1111/pace.15172","DOIUrl":"10.1111/pace.15172","url":null,"abstract":"","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"488-491"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuf Ziya Sener, Sumeyye Fatma Ozer, Gizem Karahan
{"title":"A Current Perspective on Left Atrial Appendage Closure Device Infections: A Systematic Review.","authors":"Yusuf Ziya Sener, Sumeyye Fatma Ozer, Gizem Karahan","doi":"10.1111/pace.15184","DOIUrl":"10.1111/pace.15184","url":null,"abstract":"<p><strong>Purpose: </strong>Left atrial appendage (LAA) closure has become the standard of care for patients with atrial fibrillation (AF) at high risk of thromboembolism who are intolerant or unwilling to take anticoagulants. LAA occlusion device infection is a challenging complication, and there is a paucity of data on the management and outcomes of LAA occlusion device infection. We aimed to summarize the existing literature and highlight the knowledge gap in this area.</p><p><strong>Methods: </strong>A detailed search was conducted through the databases PubMed/MEDLINE, EMBASE, Web of Science, CINAHL, and Cochrane Central using the relevant keywords. All cases with presented data regarding diagnosis, treatment, and outcome were included from the reports.</p><p><strong>Results: </strong>The analysis included 12 case reports encompassing a total of 12 patients. The mean age was 73.6 ± 11.0 years, and 50% of the cases were male. The most commonly implanted device was the Watchman (in eight of the 12 cases). The median time between LAA closure and infection was 6.6 (0.2-36) months. Transesophageal echocardiography was diagnostic in all cases, and positron emission tomography/computed tomography (PET/CT) was useful in diagnosis in three cases. The most common pathogen was Staphylococcus aureus (n = 7). The LAAC device was removed in seven cases; one patient refused surgery, and in the other three cases, removal of the device was not considered appropriate due to the patient's poor condition. Data on whether the device was removed could not be retrieved for one patient. Mortality occurred in three cases (25%), and all deaths occurred during hospitalization.</p><p><strong>Conclusion: </strong>LAA closure device infections are rare but carry a high risk of complications and mortality. Treatment should include device removal in appropriate cases, and antibiotherapy alone should be considered only in selected cases. Further studies are needed to clarify diagnostic and treatment strategies based on the causative pathogens and patient status.</p>","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"492-499"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-Term Follow-Up of Left Bundle Branch Area Pacing in Pacing-Dependent Patients and Normal Cardiac Function.","authors":"Yunjie Yao, Minmin Sun, Yufeng Sheng, Chunming Xu, Chen Ren, Aiping Song, Jiaqun Gu, Kebei Li","doi":"10.1111/pace.15188","DOIUrl":"10.1111/pace.15188","url":null,"abstract":"<p><strong>Introduction: </strong>Left bundle branch area pacing (LBBAP) has emerged as a novel physiological pacing strategy. The purpose of this study was to evaluate the long-term effect of LBBAP in ventricular pacing-dependent patients and baseline normal cardiac function.</p><p><strong>Methods: </strong>This retrospective observational study included patients who underwent LBBAP or RVP for bradycardia indications between January 2018 and July 2021. Baseline characteristics and electrophysiological, pacing and echocardiographic data were collected.</p><p><strong>Results: </strong>Sixty patients with VP% ≥ 40% were enrolled, including 30 patients in the LBBAP group and 30 patients in the RVP group. The mean follow-up time was 53.03 ± 8.10 months in the LBBAP group and 51.87 ± 11.68 months in the RVP group. No ventricular septum perforation was observed during the procedure or follow-up. The R-wave amplitudes did not differ between the two groups at implantation, but the R-wave amplitude in the LBBAP group at last follow-up was higher than that in the RVP group (17.67 ± 7.50 mV vs. 12.38 ± 5.36 mV, p = 0.003). Paced QRS duration in the LBBAP group was significantly shorter than that in the RVP group (138.93 ± 15.36 ms vs. 164.30 ± 19.48 ms, p < 0.0001). The LBBAP group had a higher LVEF (64.81 ± 5.49 vs. 60.44 ± 9.28, p = 0.041) and lower LVESD (29.70 ± 4.59 mm vs. 32.03 ± 3.97 mm, p = 0.039) than the RVP group at last follow-up.</p><p><strong>Conclusion: </strong>This study found LBBAP electrodes had a stable anatomic position, better pacing parameters, and better maintaining cardiac performances than RVP in patients with normal cardiac function and bradyarrhythmia indications.</p>","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":"48 5","pages":"480-487"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haoming You, Sitong Li, Xueyuan Guo, Chao Jiang, Lu Zhou, Liu He, Wei Wang, Songnan Li, Ribo Tang, Nian Liu, Chenxi Jiang, Ronghui Yu, Ning Zhou, Caihua Sang, Deyong Long, Xin Du, Changsheng Ma, Jianzeng Dong
{"title":"Antiarrhythmic Drug Use in the Blanking Period After Re-Ablation and Recurrence in Paroxysmal Atrial Fibrillation.","authors":"Haoming You, Sitong Li, Xueyuan Guo, Chao Jiang, Lu Zhou, Liu He, Wei Wang, Songnan Li, Ribo Tang, Nian Liu, Chenxi Jiang, Ronghui Yu, Ning Zhou, Caihua Sang, Deyong Long, Xin Du, Changsheng Ma, Jianzeng Dong","doi":"10.1111/pace.15181","DOIUrl":"10.1111/pace.15181","url":null,"abstract":"<p><strong>Background: </strong>The effectiveness of continuous anti-arrhythmic drugs (AAD) therapy during the 3-month blanking period following repeat catheter ablation to prevent atrial fibrillation (AF) recurrence remains unclear. To evaluate the impact of continuous AAD therapy during the blanking period on AF recurrence in patients with paroxysmal atrial fibrillation (PAF) undergoing repeat ablation.</p><p><strong>Methods: </strong>Patients with PAF who underwent repeat ablation from the China-AF Registry (2011-2022) were included in this study and categorized into two groups based on AAD use during the 3-month blanking period. The AF recurrence was defined as recurrent atrial tachyarrhythmias lasting for >30 s following the blanking period. Cox proportional hazard models were performed to assess the association between AAD status in the blanking period and AF recurrence at 12 months.</p><p><strong>Results: </strong>The study included 740 PAF patients (mean age 59.4 ± 10.6 years, 36.1% female) who underwent repeat ablation, with 289 patients in the on-AAD group and 451 in the off-AAD group. At 12 months post-ablation, 258 patients (34.9%) experienced AF recurrence. After adjusting for confounders, AAD use during the blanking period did not significantly associate with AF recurrence within 12 months after this period (HR = 1.07; 95% CI: 0.83-1.37; p = 0.599). Consistent results were found in different age, sex, body mass index, left atrial diameter, and CHA<sub>2</sub>DS<sub>2</sub>-VASc score subgroups.</p><p><strong>Conclusions: </strong>There was no significant relationship between AAD therapy during the blanking period after repeat ablation and AF recurrence at 12 months in patients with PAF.</p>","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"529-537"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of Pulmonary Vein Isolation by Local Potentials in FARAPULSE Pulsed Field Ablation System.","authors":"Saki Yamano, Tetsuma Kawaji, Misaki Naka, Kaisei Yanada, Yuki Ueda, Ryuta Ishida, Masashi Kato, Takafumi Yokomatsu, Shinji Miki","doi":"10.1111/pace.15176","DOIUrl":"10.1111/pace.15176","url":null,"abstract":"<p><p>Herein, we propose a novel approach examining intra-spline bipolar potentials-rather than conventional cross-spline potentials-using the FARAWAVE catheter to assess pulmonary vein isolation in the FARAPULSE pulsed field ablation system. The novel intra-spline bipolar electrograms on the FARAWAVE catheter are useful for reducing far potentials during confirmation of the pulmonary vein isolation line.</p>","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"500-503"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaofei Li, Xiaohan Fan, Chen He, Bowen Fan, Lingan Liu, Haojie Zhu, Zhicheng Hu, Limin Liu, Tao Zhang, Yan Xiao, Kun Fang, Yan Yao
{"title":"Iatrogenic Arteriovenous Fistula After Pacemaker Implantation: A Rare Case Report and Literature Review.","authors":"Xiaofei Li, Xiaohan Fan, Chen He, Bowen Fan, Lingan Liu, Haojie Zhu, Zhicheng Hu, Limin Liu, Tao Zhang, Yan Xiao, Kun Fang, Yan Yao","doi":"10.1111/pace.15174","DOIUrl":"10.1111/pace.15174","url":null,"abstract":"<p><p>Severe vascular complications associated with pacemaker implantation rarely occur and then might be misjudged. We presented a case with an atypical and confusing presentation of arteriovenous fistulae after pacemaker implantation that was relatively late recognized post-procedure. Endovascular repairment was performed and a good clinical outcome was reached.</p>","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"504-507"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samuel F Sears, Maeve M Sargeant, Brigham Godfrey, Christopher Thorne, Linda Justice, Rahul Jain, Joshua Silverstein, Amit Thosani, Jose Osorio, Allyson L Varley
{"title":"Prevalence of Burnout Symptoms in Cardiac Electrophysiologists in a US Sample.","authors":"Samuel F Sears, Maeve M Sargeant, Brigham Godfrey, Christopher Thorne, Linda Justice, Rahul Jain, Joshua Silverstein, Amit Thosani, Jose Osorio, Allyson L Varley","doi":"10.1111/pace.15187","DOIUrl":"10.1111/pace.15187","url":null,"abstract":"<p><strong>Introduction: </strong>Physician burnout is a common problem across the field of medicine, resulting in significant negative personal and work-related consequences. We set out to explore the prevalence of burnout in cardiac electrophysiologists (EPs).</p><p><strong>Methods: </strong>A national registry of EPs (N = 112) was sent a two-item questionnaire, established and validated to assess the experience of Burnout. In total, 51 EPs completed the questionnaire from 2020 to 2023.</p><p><strong>Results: </strong>36% of the sampled cardiac electrophysiologists reported burnout, and 26% reported feelings of callousness.</p><p><strong>Conclusion: </strong>This significant number of EPs experiencing symptoms of burnout underscores the critical need for enhanced focus on the EP workforce.</p>","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"557-559"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas Fink, Vanessa Sciacca, Kevin Bannmann, Maximilian Moersdorf, Sebastian Beyer, Alessandro Parlato, Denise Guckel, Mustapha El Hamriti, Moneeb Khalaph, Martin Braun, Maxim Didenko, Guram Imnadze, Dominik Linz, Kevin Vernooy, Philipp Sommer, Christian Sohns
{"title":"First Experience Using a Novel Variable Loop Catheter for Mapping and Pulsed Field Ablation of Atrial Fibrillation.","authors":"Thomas Fink, Vanessa Sciacca, Kevin Bannmann, Maximilian Moersdorf, Sebastian Beyer, Alessandro Parlato, Denise Guckel, Mustapha El Hamriti, Moneeb Khalaph, Martin Braun, Maxim Didenko, Guram Imnadze, Dominik Linz, Kevin Vernooy, Philipp Sommer, Christian Sohns","doi":"10.1111/pace.15177","DOIUrl":"10.1111/pace.15177","url":null,"abstract":"<p><strong>Background and aims: </strong>A novel multielectrode variable loop catheter (VLC) has been introduced for atrial fibrillation (AF) ablation enabling 3D electroanatomic mapping and concomitant pulsed field ablation (PFA). This study sought to investigate the VLC under routine clinical conditions for AF ablation.</p><p><strong>Methods: </strong>Consecutive patients with symptomatic AF undergoing first-time AF ablation were prospectively enrolled. All procedures were carried out using the VLC. Electroanatomic mapping pre and post-ablation was conducted with the VLC and a high-density multipolar mapping catheter. The general ablation protocol consisted of four ablation pulses per pulmonary vein (PV). All procedures were conducted in conscious sedation.</p><p><strong>Results: </strong>Forty-five patients (mean age 66.3 ± 6.1 years, 68.9% paroxysmal AF) were analyzed. Procedure duration was 66.3 ± 13.1 min. Acute pulmonary vein isolation (PVI) was achieved in 45 patients without periprocedural complications. Remapping after the initial 16 ablation pulses revealed sustained electrical conduction to at least one PV in six patients (13.3%). Repeat ablation was conducted and with an average of 7.5 ± 4.5 additional pulses. PV intubation during mapping was achieved in 168/180 PVs with the VLC (93.3%) and in 180/180PVs (100%) with the high-density mapping catheter (p < 0.001). Incomplete PV intubation during mapping did not result in incomplete PVI, as demonstrated by remapping utilizing the high-density mapping catheter. Adequate correlation between left atrial post-ablation remapping of low voltage areas and ablated regions was demonstrated in all patients.</p><p><strong>Conclusion: </strong>PFA-guided AF ablation using the novel VLC is safe and effective. The integration into a 3D-electroanatomic mapping system enables adequate mapping during PFA procedures.</p>","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"471-479"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to \"Multistep Algorithm to Predict RVOT PVC Site of Origin for Successful Ablation Using Available Criteria-A Two-Center Cross-Validation Study\".","authors":"","doi":"10.1111/pace.15171","DOIUrl":"https://doi.org/10.1111/pace.15171","url":null,"abstract":"","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":"48 5","pages":"564-565"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karanjeet Chauhan, Alistair Royse, Colin Royse, Joseph Morton, Gareth Wynn
{"title":"Right Bundle Branch Block After Transvenous Lead Extraction: An Unreported Complication With Potentially Severe Outcomes.","authors":"Karanjeet Chauhan, Alistair Royse, Colin Royse, Joseph Morton, Gareth Wynn","doi":"10.1111/pace.15182","DOIUrl":"10.1111/pace.15182","url":null,"abstract":"<p><strong>Introduction: </strong>Right bundle branch block (RBBB) following cardiac device extraction has not been previously reported but may have catastrophic consequences.</p><p><strong>Methods and results: </strong>We present two cases of young male patients who developed RBBB following the extraction of single chamber TV ICD systems where the coil was adherent close to the superior tricuspid valve annulus. Both patients had a subcutaneous ICD (SICD) implanted but suffered an inappropriate shock due to T-wave oversensing, requiring very early SICD removal for one patient.</p><p><strong>Conclusion: </strong>The development of RBBB following the extraction of a TV ICD is a previously unreported complication and may cause significant sensing problems if an SICD is implanted subsequently. Placement of the ICD lead tip in the right ventricular outflow tract or high on the intraventricular septum may predispose to this complication.</p>","PeriodicalId":54653,"journal":{"name":"Pace-Pacing and Clinical Electrophysiology","volume":" ","pages":"508-512"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12063196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}