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Molecular Markers in the World Health Organization Classification of Head and Neck Tumors, Fifth Edition. 世界卫生组织头颈部肿瘤分类(第五版)中的分子标记物。
IF 5.2 1区 医学
Radiographics Pub Date : 2024-10-01 DOI: 10.1148/rg.240037
Amit Agarwal, Girish Bathla, Alok Bhatt, John Murray, Dinesh Rao, Kanupriya Vijay, Patricia Rhyner, Prasanna Vibhute
{"title":"Molecular Markers in the World Health Organization Classification of Head and Neck Tumors, Fifth Edition.","authors":"Amit Agarwal, Girish Bathla, Alok Bhatt, John Murray, Dinesh Rao, Kanupriya Vijay, Patricia Rhyner, Prasanna Vibhute","doi":"10.1148/rg.240037","DOIUrl":"https://doi.org/10.1148/rg.240037","url":null,"abstract":"<p><p>The past decade has seen exponential advancements in molecular markers and the genetics of tumors, recognizing the limitations of conventional histopathology for grading, classification, and prognostication. Such advances have resulted in changes to classification systems, for example, with the incorporation of objective molecular and genetic information into the 2021 World Health Organization (WHO) classification of central nervous system tumors. The fifth edition of the WHO classification of head and neck tumors (HN5) (beta online version, 2022) also introduced major changes based on molecular markers, including additions, deletions, and reclassifications of entities, with the idea of being more objective and standardized. These changes are highly relevant to therapy decisions, prognosis, and clinical research and for patients with resistant diseases to explore options in clinical trials. The HN5, for the first time, included a radiologist as a member of the writing team to incorporate pertinent imaging findings into the classification. It is important for the radiologist, as an integral part of the multidisciplinary team, to be up to date about these changes for a better understanding of tumor biology, to integrate this into their clinical practice, and to provide more value in their interpretations. The authors provide a basic understanding of pathology and genetics for the radiologist, highlighting the molecular changes in epithelial (including squamous cell) and nonepithelial tumors of the head and neck. The authors also highlight newly recognized and reclassified tumor entities and provide a brief discussion on the genetic tumor syndromes. <sup>©</sup>RSNA, 2024 Supplemental material is available for this article. See the invited commentary by Junn and Baugnon in this issue.</p>","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"44 10","pages":"e240037"},"PeriodicalIF":5.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sinonasal Tumors: What the Multidisciplinary Cancer Care Board Wants to Know. 鼻窦肿瘤:多学科癌症护理委员会想知道什么?
IF 5.5 1区 医学
Radiographics Pub Date : 2024-10-01 DOI: 10.1148/rg.240035
Gregory D Avey,Ian J Koszewski,Mohit Agarwal,Levi A Endelman,Marin A McDonald,Adam R Burr,Justine Yang Bruce,Lauren Penn,Tabassum A Kennedy
{"title":"Sinonasal Tumors: What the Multidisciplinary Cancer Care Board Wants to Know.","authors":"Gregory D Avey,Ian J Koszewski,Mohit Agarwal,Levi A Endelman,Marin A McDonald,Adam R Burr,Justine Yang Bruce,Lauren Penn,Tabassum A Kennedy","doi":"10.1148/rg.240035","DOIUrl":"https://doi.org/10.1148/rg.240035","url":null,"abstract":"Sinonasal neoplasms are a remarkably heterogeneous group, reflecting the numerous tissue types present in the nasal cavity and paranasal sinuses. These entities can be relatively benign (ie, respiratory epithelial adenomatoid hamartoma) or can be exceedingly aggressive (ie, NUT carcinoma). Certain sinonasal tumors have a propensity to spread through local invasion and destruction, while others have a high likelihood of perineural spread. The genetic and molecular mechanisms underlying sinonasal tumor behavior have recently become better understood, and new tumor types have been described using these genetic and molecular data. This has prompted an expansion in the number of tumors included in the World Health Organization fifth edition classification system for head and neck tumors, along with a new classification structure. Radiologists' familiarity with this classification structure is crucial to understanding the expected behavior of these tumors and to collaboration with the multidisciplinary cancer care board in making decisions for optimal patient care. ©RSNA, 2024.","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"75 1","pages":"e240035"},"PeriodicalIF":5.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ocular Trauma: Anatomy, Pitfalls, and Systematic Approach to Imaging Interpretation. 眼外伤:解剖学、陷阱和成像解读的系统方法》。
IF 5.2 1区 医学
Radiographics Pub Date : 2024-10-01 DOI: 10.1148/rg.240051
Omar Andrés Pantoja Burbano, María Alejandra Amaya Trigos, Felipe Aluja Jaramillo, Carolina Tramontini Jens
{"title":"Ocular Trauma: Anatomy, Pitfalls, and Systematic Approach to Imaging Interpretation.","authors":"Omar Andrés Pantoja Burbano, María Alejandra Amaya Trigos, Felipe Aluja Jaramillo, Carolina Tramontini Jens","doi":"10.1148/rg.240051","DOIUrl":"10.1148/rg.240051","url":null,"abstract":"","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"44 10","pages":"e240051"},"PeriodicalIF":5.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Head and Neck Imaging: Cutting-Edge Techniques and Transformative Insights The 2024 RadioGraphics Monograph Issue. 头颈部成像:前沿技术和变革性见解 2024 年 RadioGraphics 专刊。
IF 5.2 1区 医学
Radiographics Pub Date : 2024-10-01 DOI: 10.1148/rg.249007
Suyash Mohan, Paul M Bunch, Christine M Glastonbury
{"title":"Head and Neck Imaging: Cutting-Edge Techniques and Transformative Insights The 2024 <i>RadioGraphics</i> Monograph Issue.","authors":"Suyash Mohan, Paul M Bunch, Christine M Glastonbury","doi":"10.1148/rg.249007","DOIUrl":"https://doi.org/10.1148/rg.249007","url":null,"abstract":"","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"44 10","pages":"e249007"},"PeriodicalIF":5.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultra-High-Resolution Temporal Bone Anatomy Using Photon-counting CT: Added Value of Improved Spatial Resolution. 利用光子计数 CT 进行超高分辨率颞骨解剖:提高空间分辨率的附加值。
IF 5.5 1区 医学
Radiographics Pub Date : 2024-10-01 DOI: 10.1148/rg.240028
Shehbaz Ansari,Miral D Jhaveri,Pokhraj Prakashchandra Suthar,Jeffrey DeSanto,Santhosh Gaddikeri,Surjith Vattoth
{"title":"Ultra-High-Resolution Temporal Bone Anatomy Using Photon-counting CT: Added Value of Improved Spatial Resolution.","authors":"Shehbaz Ansari,Miral D Jhaveri,Pokhraj Prakashchandra Suthar,Jeffrey DeSanto,Santhosh Gaddikeri,Surjith Vattoth","doi":"10.1148/rg.240028","DOIUrl":"https://doi.org/10.1148/rg.240028","url":null,"abstract":"","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"189 1","pages":"e240028"},"PeriodicalIF":5.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142268292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nontraumatic Pediatric Head and Neck Emergencies: Resource for On-Call Radiologists. 非外伤性小儿头颈部急症:放射科值班医生资源。
IF 5.5 1区 医学
Radiographics Pub Date : 2024-10-01 DOI: 10.1148/rg.240027
Alexandra M Foust,Lindsey Johnstone,Rekha Krishnasarma,Dann C Martin,Jennifer Vaughn,Karuna Shekdar,Elizabeth Snyder,Ty Todd,Sumit Pruthi,Asha Sarma
{"title":"Nontraumatic Pediatric Head and Neck Emergencies: Resource for On-Call Radiologists.","authors":"Alexandra M Foust,Lindsey Johnstone,Rekha Krishnasarma,Dann C Martin,Jennifer Vaughn,Karuna Shekdar,Elizabeth Snyder,Ty Todd,Sumit Pruthi,Asha Sarma","doi":"10.1148/rg.240027","DOIUrl":"https://doi.org/10.1148/rg.240027","url":null,"abstract":"The vast array of acute nontraumatic diseases encountered in the head and neck of pediatric patients can be intimidating for radiologists in training in a fast-paced emergency setting. Although there is some overlap of pediatric and adult diseases, congenital lesions and developmental variants are much more common in the pediatric population. Furthermore, the relative incidences of numerous infections and neoplasms differ between pediatric and adult populations. Young patients and/or those with developmental delays may have clinical histories that are difficult to elicit or nonspecific presentations, underscoring the importance of imaging in facilitating accurate and timely diagnoses. It is essential that radiologists caring for children be well versed in pediatric nontraumatic head and neck emergency imaging. The authors provide an on-call resource for radiology trainees, organized by anatomic location and highlighting key points, pearls, pitfalls, and mimics of many acute nontraumatic diseases in the pediatric head and neck. ©RSNA, 2024 Supplemental material is available for this article.","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"14 1","pages":"e240027"},"PeriodicalIF":5.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critical Role of Advanced Imaging in Managing Behçet Syndrome: Multidisciplinary Approach to Ophthalmic and Thoracic Complications. 先进成像技术在治疗贝赫切特综合征中的关键作用:眼科和胸腔并发症的多学科方法。
IF 5.2 1区 医学
Radiographics Pub Date : 2024-09-01 DOI: 10.1148/rg.240225
Furkan Ufuk, Luis Landeras
{"title":"Critical Role of Advanced Imaging in Managing Behçet Syndrome: Multidisciplinary Approach to Ophthalmic and Thoracic Complications.","authors":"Furkan Ufuk, Luis Landeras","doi":"10.1148/rg.240225","DOIUrl":"10.1148/rg.240225","url":null,"abstract":"","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"44 9","pages":"e240225"},"PeriodicalIF":5.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diffusely Infiltrative Small Bowel Disease. 弥漫浸润性小肠疾病
IF 5.2 1区 医学
Radiographics Pub Date : 2024-09-01 DOI: 10.1148/rg.230148
Preet Dhillon, Madeline Naidu, Michael C Olson, Wendaline M VanBuren, Shannon P Sheedy, Michael L Wells, Jeff L Fidler, Jay P Heiken, Sudhakar K Venkatesh, Zachary S Kelm
{"title":"Diffusely Infiltrative Small Bowel Disease.","authors":"Preet Dhillon, Madeline Naidu, Michael C Olson, Wendaline M VanBuren, Shannon P Sheedy, Michael L Wells, Jeff L Fidler, Jay P Heiken, Sudhakar K Venkatesh, Zachary S Kelm","doi":"10.1148/rg.230148","DOIUrl":"https://doi.org/10.1148/rg.230148","url":null,"abstract":"<p><p>Multiple infiltrative disorders can affect the small bowel, often resulting in diffuse small bowel wall thickening. These infiltrative disorders can manifest owing to various factors such as an influx of immunologic or neoplastic cells or the accumulation of substances within one or more layers of the intestinal wall. Although there can be considerable overlap in the appearances of infiltrative diseases on cross-sectional images, a comprehensive understanding of more specific ancillary imaging features and clinicopathologic correlation can substantially narrow the differential diagnosis. The radiologist can be instrumental in synthesizing the clinical and imaging information and guiding subsequent workup. The authors present a comprehensive review of the infiltrative disorders that commonly involve the small bowel. These disorders are organized on the basis of their pathophysiologic features, with multiple illustrative case examples to enhance understanding of these entities. CT and MRI are currently the most commonly used imaging modalities for evaluating small bowel disorders, and this review is focused on these two modalities. Detailed information regarding the pathologic features, clinical presentation, and imaging findings of these infiltrative disorders is provided to aid radiologists in recognizing and differentiating these conditions. <sup>©</sup>RSNA, 2024.</p>","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"44 9","pages":"e230148"},"PeriodicalIF":5.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Lung Anomalies in Adults. 成人先天性肺部异常。
IF 5.2 1区 医学
Radiographics Pub Date : 2024-09-01 DOI: 10.1148/rg.240017
Marcos Mestas Nuñez, Gonzalo Dulcich, Carlos S Restrepo, Ranish Khawaja, Nakul Shankar, Nicole Restauri, Jordi Broncano, Daniel Vargas
{"title":"Congenital Lung Anomalies in Adults.","authors":"Marcos Mestas Nuñez, Gonzalo Dulcich, Carlos S Restrepo, Ranish Khawaja, Nakul Shankar, Nicole Restauri, Jordi Broncano, Daniel Vargas","doi":"10.1148/rg.240017","DOIUrl":"https://doi.org/10.1148/rg.240017","url":null,"abstract":"<p><p>Congenital lung anomaly (CLA) refers to a rare group of malformations that are typically identified prenatally or in early childhood. However, a significant proportion of cases evade detection until adulthood and either are incidentally discovered or manifest with symptoms of recurrent respiratory infection or pulmonary hemorrhage. While most CLAs have characteristic imaging findings at CT and MRI, they remain a diagnostic challenge due to the infrequency with which they are encountered in adults. Radiologists frequently play a pivotal role in suggesting the diagnosis and guiding appropriate management strategies, and recognition of characteristic imaging patterns is crucial for accurate diagnosis. The authors examine the imaging appearances and clinical manifestations in adult patients with CLA, with a focus on patients who have bronchopulmonary involvement and those with combined bronchopulmonary and vascular anomalies. Entities discussed include bronchogenic cyst, bronchial atresia, congenital lobar overinflation, congenital pulmonary airway malformation, proximal interruption of the pulmonary artery, bronchopulmonary sequestration, hypogenetic lung syndrome, placental transmogrification of the lung, and hybrid lesions. Common complications that may arise in these patients are discussed and illustrated. <sup>©</sup>RSNA, 2024 <i>Supplemental material is available for this article.</i></p>","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"44 9","pages":"e240017"},"PeriodicalIF":5.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum for: Anatomic Basis of Rectal Cancer Staging: Clarifying Controversies and Misconceptions. 勘误表直肠癌分期的解剖学基础:澄清争议和误解。
IF 5.2 1区 医学
Radiographics Pub Date : 2024-09-01 DOI: 10.1148/rg.249006
Harmeet Kaur, Helena Gabriel, Muhammad O Awiwi, Ekta Maheshwari, Camila Lopes Vendrami, Tsuyoshi Konishi, Melissa W Taggart, Michael Magnetta, Linda C Kelahan, Sonia Lee
{"title":"Erratum for: Anatomic Basis of Rectal Cancer Staging: Clarifying Controversies and Misconceptions.","authors":"Harmeet Kaur, Helena Gabriel, Muhammad O Awiwi, Ekta Maheshwari, Camila Lopes Vendrami, Tsuyoshi Konishi, Melissa W Taggart, Michael Magnetta, Linda C Kelahan, Sonia Lee","doi":"10.1148/rg.249006","DOIUrl":"https://doi.org/10.1148/rg.249006","url":null,"abstract":"","PeriodicalId":54512,"journal":{"name":"Radiographics","volume":"44 9","pages":"e249006"},"PeriodicalIF":5.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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