Mucinous Appendiceal Neoplasms and Pseudomyxoma Peritonei: Imaging Features and Current Therapies.

IF 5.2 1区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Radiographics Pub Date : 2025-06-01 DOI:10.1148/rg.240131
Laura C Jorgenson, Sherry S Wang, Travis E Grotz, Rondell P Graham, Patrick J Navin, Christopher Favazza, Sudhakar K Venkatesh, Jeff L Fidler, Joel G Fletcher, Eric C Ehman, Shannon P Sheedy
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引用次数: 0

Abstract

Pseudomyxoma peritonei involves the gradual accumulation of gelatinous peritoneal metastases, typically resulting from the rupture of a mucinous appendiceal neoplasm. Standard treatment often includes cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. However, recurrence is common despite optimal cytoreduction, prompting ongoing investigation into novel therapies. This comprehensive review aims to enhance radiologists' understanding of mucinous appendiceal neoplasms and pseudomyxoma peritonei by focusing on nomenclature, pathophysiology, optimal imaging strategies, and the typical imaging appearance of mucinous appendiceal neoplasm and associated peritoneal disease. It also highlights problematic areas of disease that may affect the ability to achieve complete cytoreduction or influence surgical decision making and includes a surgeon's perspective on treating this complex condition.

阑尾黏液性肿瘤和腹膜假性黏液瘤:影像学特征和当前治疗方法。
腹膜假性黏液瘤涉及胶质性腹膜转移的逐渐积聚,通常由粘液性阑尾肿瘤破裂引起。标准治疗通常包括细胞减少手术和腹腔内高温化疗。然而,尽管最佳的细胞减少,复发是常见的,促使正在进行的研究新的治疗方法。本文旨在通过对阑尾黏液性肿瘤和腹膜假性黏液瘤的命名、病理生理学、最佳成像策略以及阑尾黏液性肿瘤和相关腹膜疾病的典型影像学表现进行综述,以提高放射科医生对其的认识。它还强调了可能影响完全细胞减少能力或影响手术决策的疾病问题区域,并包括外科医生对治疗这种复杂疾病的看法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Radiographics
Radiographics 医学-核医学
CiteScore
8.20
自引率
5.50%
发文量
224
审稿时长
4-8 weeks
期刊介绍: Launched by the Radiological Society of North America (RSNA) in 1981, RadioGraphics is one of the premier education journals in diagnostic radiology. Each bimonthly issue features 15–20 practice-focused articles spanning the full spectrum of radiologic subspecialties and addressing topics such as diagnostic imaging techniques, imaging features of a disease or group of diseases, radiologic-pathologic correlation, practice policy and quality initiatives, imaging physics, informatics, and lifelong learning. A special issue, a monograph focused on a single subspecialty or on a crossover topic of interest to multiple subspecialties, is published each October. Each issue offers more than a dozen opportunities to earn continuing medical education credits that qualify for AMA PRA Category 1 CreditTM and all online activities can be applied toward the ABR MOC Self-Assessment Requirement.
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