{"title":"Les printemps de la médecine interne ont 30 ans : les diagnosticiens à l’honneur","authors":"Jean-Benoît Arlet","doi":"10.1016/j.revmed.2025.01.006","DOIUrl":"10.1016/j.revmed.2025.01.006","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 2","pages":"Pages 65-67"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laurent Arnaud , Alexandra Audemard-Verger , Alexandre Belot , Boris Bienvenu , Carole Burillon , François Chasset , Florence Chaudot , Raphael Darbon , Anastasia Delmotte , Mikael Ebbo , Olivier Espitia , Anne-Laure Fauchais , Alexis F. Guedon , Eric Hachulla , Jérôme Hadjadj , Charlotte Hautefort , Vincent Jachiet , Elisabeth Mamelle , Mickael Martin , Marc Muraine , Arsène Mekinian
{"title":"French protocol for diagnosis and management of Cogan's syndrome","authors":"Laurent Arnaud , Alexandra Audemard-Verger , Alexandre Belot , Boris Bienvenu , Carole Burillon , François Chasset , Florence Chaudot , Raphael Darbon , Anastasia Delmotte , Mikael Ebbo , Olivier Espitia , Anne-Laure Fauchais , Alexis F. Guedon , Eric Hachulla , Jérôme Hadjadj , Charlotte Hautefort , Vincent Jachiet , Elisabeth Mamelle , Mickael Martin , Marc Muraine , Arsène Mekinian","doi":"10.1016/j.revmed.2024.09.007","DOIUrl":"10.1016/j.revmed.2024.09.007","url":null,"abstract":"<div><div>Cogan's syndrome is a condition of unknown origin, classified as a systemic vasculitis. It is characterised by a predilection for the cornea and the inner ear. It mainly affects Caucasian individuals with a sex-ratio close to one. Ophthalmological and cochleo-vestibular involvement are the most common manifestations of the disease. The most frequent ophthalmological type of involvement is non-syphilitic interstitial keratitis. Cochleo-vestibular manifestations are similar to those of Meniere's syndrome. The disease progresses in ocular and ear-nose-throat (ENT) flares, which may occur simultaneously or in isolation. Association with other autoimmune diseases, particularly other forms of vasculitis such as polyarteritis nodosa or Takayasu's arteritis, is possible. Ocular involvement, as well as cochleo-vestibular involvement, can be inaugural and initially isolated. Onset is often abrupt. The characteristic involvement is “non-syphilitic” interstitial keratitis. It is usually bilateral from the outset or becomes so during the course of the disease. It presents as a red, painful eye, possibly associated with decreased visual acuity. Cochleo-vestibular involvement is usually bilateral from the outset. It is characterised by the sudden onset of continuous rotational vertigo associated with tinnitus, rapidly progressive sensorineural deafness. Approximately 30–70% of patients present with systemic manifestations. Deterioration in general status with fever may be present. Laboratory evidence of inflammatory syndrome is associated in 75% of cases. Cogan's syndrome is a presumed autoimmune type of vasculitis, although no specific autoantibodies have been identified. Ocular involvement is usually associated with a good prognosis, with total visual acuity recovery in the majority of cases. In contrast, cochleo-vestibular involvement can be severe and irreversible. Therapeutic management of Cogan's syndrome, given its rarity, lacks consensus since no prospective randomised studies have been conducted to date. Corticosteroid therapy is the first-line treatment. Combination with anti-TNF therapy should be promptly discussed.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 2","pages":"Pages 74-88"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Grégoire Martin de Frémont , Kevin Chevalier , Anaïs Roeser
{"title":"Portrait de Loïc Raffray, PU–PH et chef de service de médecine interne au CHU de La Réunion","authors":"Grégoire Martin de Frémont , Kevin Chevalier , Anaïs Roeser","doi":"10.1016/j.revmed.2024.12.001","DOIUrl":"10.1016/j.revmed.2024.12.001","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 2","pages":"Pages 126-128"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magali Le Brun , Dominique Godard , Lila Camps , Quentin Gomes de Pinho , Audrey Benyamine , Brigitte Granel
{"title":"La littératie en santé : définition, outils d’évaluation, état des lieux en Europe, conséquences pour la santé et moyens disponibles pour l’améliorer","authors":"Magali Le Brun , Dominique Godard , Lila Camps , Quentin Gomes de Pinho , Audrey Benyamine , Brigitte Granel","doi":"10.1016/j.revmed.2024.06.014","DOIUrl":"10.1016/j.revmed.2024.06.014","url":null,"abstract":"<div><div>The term “littératie” is derived from the English word “literacy”, which refers to knowledge and skills in the fields of reading, writing, speech (or other means of communication) and calculation that allow people to be efficient and integrated into society. Health literacy is a recent concept that relies on the ability to find, understand, evaluate and communicate information in ways that promote, maintain and improve the health of the individual in various settings over the course of life. The objectives of this review are first of all to realize an overview on the health literacy of populations in Europe. Then, we propose to study the link between health literacy and health status (risk behaviors, chronic diseases, morbi-mortality, adherence to care and medical monitoring) and to study its medico-economic impact. We also analyzed the association between personalized therapeutic education and health literacy. Finally, we propose a review of the means put in place in the care system to improve the health literacy of the patients we manage.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 1","pages":"Pages 32-39"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fièvre Q chronique. Revue de la littérature à propos d’un cas de spondylodicite à hémocultures négatives","authors":"Florentin Masoch , Yoann Roubertou , Claire Triffault-Fillit , Sibylle Guillou , Marie Meignien , Maël Richard , Isabelle Durieu , Romain Euvrard","doi":"10.1016/j.revmed.2024.09.006","DOIUrl":"10.1016/j.revmed.2024.09.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Fever is a cosmopolit zoonosis due to <em>Coxiella burnetii</em>. The diagnosis of chronic Q fever can be really misleading. The growth of this bacterium is difficult and blood cultures are often negatives.</div></div><div><h3>Case presentation</h3><div>We rapport here the case of a 69-year-old man presenting with an alteration of his general condition and low back pain. He suffered from a well-controlled HIV infection and lower limb arteriopathy treated with a cross-femoral bypass. A computed tomography scan revealed a L3–L4 abscessed spondylodiscitis but multiple blood cultures remained sterile, and the transthoracic echocardiography was normal. PET scan showed a hypermetabolism on L3–L4 vertebrae but also indicated an intense uptake of the cross-femoral bypass. <em>C. burnetii</em> serology was in favour of a chronic Q fever. The management of this chronic Q fever needed a multidisciplinary discussion. Three months after the treatment initiation, <em>C. burnetii</em> serology was reduced by a titer and has stabilized 6<!--> <!-->months to a year.</div></div><div><h3>Conclusion</h3><div>Chronic Q fever and mostly osteoarticular diseases are difficult to diagnose. We have to evoke the diagnosis of osteoarticular chronic Q fever in case of insidious inflammatory syndrome, negatives blood cultures spondylodiscitis especially when associated to endocarditis or vascular infection, and in case of spondylodiscitis with a granulomatous histology without <em>Mycobacterium tuberculosis</em>. Although there are many complementary tests (PET scanner, PCR), serology remains the cornerstone of diagnosis.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 1","pages":"Pages 49-54"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hubert de Boysson , Valérie Devauchelle-Pensec , Christian Agard , Marc André , Boris Bienvenu , Bernard Bonnotte , Guillermo Carvajal Alegria , Olivier Espitia , Eric Hachulla , Emmanuel Héron , Marc Lambert , Jean-Christophe Lega , Kim H. Ly , Arsène Mekinian , Jacques Morel , Alexis Régent , Christophe Richez , Laurent Sailler , Raphaele Seror , Anne Tournadre , Maxime Samson
{"title":"Use of immunosuppressants and biologics in giant cell arteritis: Recommendations of the French Study Group for Large Vessel Vasculitis (GEFA)","authors":"Hubert de Boysson , Valérie Devauchelle-Pensec , Christian Agard , Marc André , Boris Bienvenu , Bernard Bonnotte , Guillermo Carvajal Alegria , Olivier Espitia , Eric Hachulla , Emmanuel Héron , Marc Lambert , Jean-Christophe Lega , Kim H. Ly , Arsène Mekinian , Jacques Morel , Alexis Régent , Christophe Richez , Laurent Sailler , Raphaele Seror , Anne Tournadre , Maxime Samson","doi":"10.1016/j.revmed.2024.10.006","DOIUrl":"10.1016/j.revmed.2024.10.006","url":null,"abstract":"<div><h3>Purpose</h3><div>An updated revision of the 2016 recommendations from the French Study Group for Large Vessel Vasculitis (GEFA) was needed to better delineate the place and management of immunosuppressants or biologics in giant cell arteritis (GCA).</div></div><div><h3>Methods</h3><div>A panel of 18 physicians, including internists and rheumatologists, constituted the task force of this project and drafted the recommendations. Twelve additional readers were asked to analyse and comment on the recommendations. Two face-to-face virtual meetings were held to discuss and validate the recommendations. Each member voted individually, and a<!--> <!-->><!--> <!-->85% consensus was required to validate each recommendation.</div></div><div><h3>Results</h3><div>From the initial 6 questions, 26 recommendations were validated. The following main recommendations were validated. (1) Subcutaneous 162<!--> <!-->mg tocilizumab (TCZ) for at least 12<!--> <!-->months should be used first when glucocorticoid (GC)-sparing treatment is needed with the objective of discontinuing GCs within the subsequent 6<!--> <!-->months. (2) GCA patients who have experienced any of the following conditions must receive TCZ at GCA diagnosis with 6<!--> <!-->months of GC therapy: major cardiovascular event, osteoporosis with fracture, psychiatric event with GC use, complicated diabetes mellitus, or any previous<!--> <!-->><!--> <!-->6<!--> <!-->months of GC treatment. (3) In patients in whom GC discontinuation is not possible after 12<!--> <!-->months of treatment because of persistent disease activity or in patients in whom GC-related adverse events are unacceptable, TCZ (or alternatively methotrexate) may be proposed.</div></div><div><h3>Conclusions</h3><div>These recommendations were constructed based on the results of the published literature and the experts’ experiences to standardise therapeutic practices in France. Further updates will likely be necessary following new publications.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 1","pages":"Pages 4-11"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relecteurs 2024 pour La revue de médecine interne","authors":"","doi":"10.1016/j.revmed.2025.01.002","DOIUrl":"10.1016/j.revmed.2025.01.002","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 1","pages":"Page 63"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143205447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Grégoire Martin de Frémont , Kevin Chevalier , Anaïs Roeser
{"title":"Portrait de Brigitte Ranque, PU-PH et cheffe de service de médecine interne à l’hôpital européen Georges-Pompidou et créatrice du circuit CASPER","authors":"Grégoire Martin de Frémont , Kevin Chevalier , Anaïs Roeser","doi":"10.1016/j.revmed.2024.11.002","DOIUrl":"10.1016/j.revmed.2024.11.002","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 1","pages":"Pages 59-62"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143205448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}