Revue De Medecine Interne最新文献

{"title":"Issue Contents","authors":"","doi":"10.1016/S0248-8663(25)00766-0","DOIUrl":"10.1016/S0248-8663(25)00766-0","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages e19-e20"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La fibrillation atriale en 2025 : diagnostic et prise en charge","authors":"Jean-Marc Sellal ,&nbsp;Néfissa Hammache ,&nbsp;Mathieu Echivard","doi":"10.1016/j.revmed.2025.02.010","DOIUrl":"10.1016/j.revmed.2025.02.010","url":null,"abstract":"<div><div>Atrial fibrillation (AF) is the most common arrhythmia. It increases the risk of hospitalization, heart failure, cognitive decline and mortality. It is the first cause of ischemic stroke. These are largely preventable if AF is diagnosed. It is essential to estimate the patient's embolic risk using the CHA2DS2-VA score, which now replaces the CHADS-Vasc score. Patients who require it must receive adequate anticoagulant treatment. New technologies (in particular, smart-watch) have led to advances in the detection and diagnosis of this arrhythmia. Patients suffering from AF may be treated with a heart rate control strategy (to limit tachycardia) or a rhythm control strategy (to maintain sinus rhythm). Catheter ablation is increasingly being offered to patients as an alternative to antiarrhythmic therapy. Controlling risk factors is essential to prevent the onset of AF, and to try to maintain sinus rhythm over the long term.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 575-579"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prise en charge initiale d’une leucémie aiguë et de ses complications","authors":"Giulia Schiavini ,&nbsp;Amandine Ségot ,&nbsp;Gerasimos Tsilimidos ,&nbsp;Vasiliki Papadopoulou ,&nbsp;Sabine Blum","doi":"10.1016/j.revmed.2025.04.025","DOIUrl":"10.1016/j.revmed.2025.04.025","url":null,"abstract":"<div><div>Acute leukemias are rare diseases requiring emergency specialized hematological care. However, other specialists may be involved: general practitioners, emergency physicians, internists and intensivists most often. The initial phase of the management of acute leukemia can be marked by the occurrence of complications with a significant impact on morbidity and mortality. The aim of this article is to guide the clinician when facing a suspected acute leukemia for the diagnosis and management of complications that may occur in the first hours. The article reviews the initial assessment, the diagnostic approach and the management of the initial complications of acute leukemia, such as DIC, tumor lysis syndrome, leukostasis syndrome and febrile agranulocytosis, whose outcome is fundamental for the prognosis.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 588-593"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phénotype de la maladie de Fabry au cours des 20 dernières années : analyse d’une cohorte de 107 patients et focus sur le variant F113L","authors":"Olivier Lidove ,&nbsp;Benjamin Subran ,&nbsp;Camille Montardi ,&nbsp;Quentin Besset ,&nbsp;Clara Mellot ,&nbsp;Julien Aki Baba ,&nbsp;Chadi Azar ,&nbsp;Jonathan London ,&nbsp;Philippe Charron ,&nbsp;Catherine Caillaud ,&nbsp;Foudil Lamari ,&nbsp;Olga Azevedo ,&nbsp;Wladimir Mauhin","doi":"10.1016/j.revmed.2025.07.007","DOIUrl":"10.1016/j.revmed.2025.07.007","url":null,"abstract":"<div><h3>Introduction</h3><div>Fabry disease (FD, #OMIM 301 500) is an X-linked lysosomal disorder. Prior to the 2000s, it was considered a male-only disease. The emergence of two intravenous enzymotherapies (2001) and then of an oral chaperone molecule (2016) brought this rare disease into the spotlight. This work describes our cohort of patients with FD and aims to analyze the predominant classical and cardiac phenotypes (including the F113L variant).</div></div><div><h3>Methods</h3><div>In December 2022, we retrospectively analyzed all patients with FD managed within the lysosomal disease reference center. We describe and compare phenotypes before and after 2012.</div></div><div><h3>Results</h3><div>Our cohort included 107 patients (48 men-M, 59 women-F). The F113L variant accounted for 18% of cases, all in patients from Portugal. Before 2012, of the 45 patients followed (21M, 24F), 29 presented a classic form with acroparesthesia and cornea verticillata (64%) and 16 a predominantly cardiac form (36%), including 4 (1MH, 3F) with F113L variant. Eight patients died of cardiac complications (5M, 3F). After 2012, 62 new patients were included (27M, 35F), with 18 classic forms (29%) and 44 predominantly cardiac forms (71%). Of the 44 patients with a predominant cardiac form, 15 (9M, 6F) carried the F113L variant. Two men with the F113L allele had a severe form of the disease, requiring pacemaker implantation following cardiac arrest following complete atrioventricular block in one (aged 48), and registration for renal transplantation at age 64 in the other.</div></div><div><h3>Conclusion</h3><div>FD affects both men and women. The predominantly cardiac phenotype is now the most fequent. It is also observed in the majority of patients with the F113L variant. Extra-cardiac involvement is possible and should be investigated if this variant is detected.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 571-574"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144857293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunoglobulines humaines polyvalentes : entre indications incontournables et usages à éviter. Actualisation en 2025 des hiérarchies de prescription proposées par l’Agence nationale de sécurité du médicament et des produits de santé (ANSM)","authors":"Bertrand Godeau,&nbsp;Luc Mouthon","doi":"10.1016/j.revmed.2025.09.001","DOIUrl":"10.1016/j.revmed.2025.09.001","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 569-570"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IA en santé : guide pour l’interniste averti","authors":"Thomas Barba,&nbsp;Marie Robert,&nbsp;Arnaud Hot","doi":"10.1016/j.revmed.2025.02.002","DOIUrl":"10.1016/j.revmed.2025.02.002","url":null,"abstract":"<div><div>Artificial intelligence (AI) is experiencing considerable growth in medicine, driven by the explosion of available biomedical data and the emergence of new algorithmic architectures. Applications are rapidly multiplying, from diagnostic assistance to disease progression prediction, paving the way for more personalized medicine. The recent advent of large language models, such as ChatGPT, has particularly interested the medical community, thanks to their ease of use, but also raised questions about their reliability in medical contexts. This review presents the fundamental concepts of medical AI, specifically distinguishing traditional discriminative approaches from new generative models. We detail the different exploitable data sources and methodological pitfalls to avoid during the development of these tools. Finally, we address the practical and ethical implications of this technological revolution, emphasizing the importance of the medical community's appropriation of these tools.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 594-600"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment peut-on aider les femmes victimes d’excision dans leur parcours de réparation ?","authors":"Mama Aissata Yattara ,&nbsp;Olivier Lidove","doi":"10.1016/j.revmed.2025.06.010","DOIUrl":"10.1016/j.revmed.2025.06.010","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 620-621"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144669207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chez les personnes atteintes de stéatohépatite associée à un dysfonctionnement métabolique (MASH) avec une fibrose hépatique modérée ou avancée, le sémaglutide à la dose de 2,4 mg sous-cutanée hebdomadaire améliore-t-il l’atteinte histologique comparativement au placebo, tout en étant sécuritaire ?","authors":"Alexandre Mutchmore ,&nbsp;Dusanka Grbic ,&nbsp;Michel Cauchon ,&nbsp;Marc-Émile Plourde ,&nbsp;Luc Lanthier","doi":"10.1016/j.revmed.2025.08.009","DOIUrl":"10.1016/j.revmed.2025.08.009","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 613-614"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Une hypophyse qui nous laisse bouche bée","authors":"Elisabeth Chene ,&nbsp;Carole Chevenet ,&nbsp;Damien Fayard ,&nbsp;Perrine Smets ,&nbsp;Ludovic Trefond ,&nbsp;Marc Andre ,&nbsp;Morgane Joubert ,&nbsp;Quiterie Reynaud","doi":"10.1016/j.revmed.2025.06.004","DOIUrl":"10.1016/j.revmed.2025.06.004","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 610-612"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144513024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical air localizations of the trunk","authors":"Monique Boukobza ,&nbsp;Lounis Hamzi ,&nbsp;Alexandre Faure ,&nbsp;Valérie Bousson ,&nbsp;Jean-Pierre Laissy","doi":"10.1016/j.revmed.2025.06.015","DOIUrl":"10.1016/j.revmed.2025.06.015","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 607-609"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144565589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}