Revue De Medecine Interne最新文献

{"title":"Portrait du Dr Thomas Girard, interniste libéral en cabinet médical à Hyères","authors":"Jonathan Sormani , Aïcha Kante , Anaïs Roeser","doi":"10.1016/j.revmed.2025.09.002","DOIUrl":"10.1016/j.revmed.2025.09.002","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 615-617"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Des genoux inflammatoires et des nodules blancs pulpaires","authors":"Coline Rabourdin, Matthieu Tournier, Quentin Gomes de Pinho, Audrey Benyamine, Brigitte Granel","doi":"10.1016/j.revmed.2025.06.007","DOIUrl":"10.1016/j.revmed.2025.06.007","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 618-619"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prise en charge d’une neutropénie fébrile post-chimiothérapie","authors":"Xavier Jannot ,&nbsp;Jean-Édouard Terrade ,&nbsp;Manuel Méndez-Bailón ,&nbsp;María Belén Alonso-Ortiz ,&nbsp;Emmanuel Andrès ,&nbsp;Noel Lorenzo-Villalba","doi":"10.1016/j.revmed.2025.04.005","DOIUrl":"10.1016/j.revmed.2025.04.005","url":null,"abstract":"<div><div>Febrile neutropenia is a medical emergency requiring rapid and rigorous management considering the risk of severe infection. Febrile neutropenia is a frequent complication in patients receiving chemotherapy. Initial assessment is vital in order to decide the follow-up (outpatient treatment, conventional care or intensive care unit) and to initiate adapted antibiotic therapy as soon as possible. Depending on the infectious syndrome (clinically documented, microbiologically documented or undocumented), antibiotic therapy should be adapted or discontinued, considering the recovery from aplasia and absence of fever. Antifungal agents are not systematically used and its use should be discussed according to the context. G-CSF should be used prophylactically, and is not an adjunct to antibiotic therapy for febrile neutropenia. Granulocyte transfusions are exceptionnally indicated and its use should be discussed on a case-by-case basis. Standard precautions are adequate for the majority of patients, with the exception of specific situations.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 580-587"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pertinence de la prescription de fer injectable : étude rétrospective monocentrique en établissement hospitalier","authors":"Aurore Ho ,&nbsp;Alice Viallet ,&nbsp;Amandine Ladaique ,&nbsp;Charlotte Delattre ,&nbsp;Delphine Beauvais ,&nbsp;Frederik Bélot-de Saint Léger ,&nbsp;Hervé Delacour ,&nbsp;Virginie Lamand ,&nbsp;Weniko Caré","doi":"10.1016/j.revmed.2025.07.003","DOIUrl":"10.1016/j.revmed.2025.07.003","url":null,"abstract":"<div><h3>Introduction</h3><div>The aim of this study was to evaluate the appropriateness of intravenous iron prescribing in our hospital setting before and after an educational campaign.</div></div><div><h3>Results</h3><div>Over two distinct periods (2021 and 2022), 239 prescriptions were analyzed. The primary indications were anemia and/or iron deficiency (83%) and blood management (13%). Compliance rates by indication were higher after the educational campaign (96 versus 95%), with fewer pharmaceutical interventions (4 versus 7), though there were no significant differences. However, compliance by length of stay was significantly higher before the educational campaign (79 versus 67%).</div></div><div><h3>Conclusion</h3><div>Compared to previous studies on the subject, the level of prescription compliance was high, including prior to the educational campaign. The campaign appeared to impact compliance by indication, but not by length of stay. A larger study would be required to confirm these results.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 10","pages":"Pages 601-606"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145035049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enquête sur les terrains de stage du diplôme d’études spécialisées (DES) de Médecine interne et Immunologie clinique : état des lieux fin 2024, sept ans après la mise en place de la réforme du troisième cycle des études médicales en France","authors":"Luc Mouthon ,&nbsp;Pascal Sève ,&nbsp;Christian Agard ,&nbsp;Marc André ,&nbsp;Emmanuel Andrès ,&nbsp;Achille Aouba ,&nbsp;Ygal Benhamou ,&nbsp;Bernard Bonnotte ,&nbsp;Laurence Bouillet ,&nbsp;Pascal Cathébras ,&nbsp;Fleur Cohen-Aubart ,&nbsp;Christophe Deligny ,&nbsp;Gilles Kaplanski ,&nbsp;Pierre Duhaut ,&nbsp;David Launay ,&nbsp;Christian Lavigne ,&nbsp;Estibaliz Lazaro ,&nbsp;Emmanuelle Le Moigne ,&nbsp;Alain Lescoat ,&nbsp;Kim Ly ,&nbsp;Odile Rauzy","doi":"10.1016/j.revmed.2025.06.008","DOIUrl":"10.1016/j.revmed.2025.06.008","url":null,"abstract":"<div><h3>Objective</h3><div>To compile a list of approved training sites for the Residency Training Program [Diplôme d’Études Spécialisées] in Internal Medicine and Clinical Immunology (DES-MIIC) in France.</div></div><div><h3>Method</h3><div>All local coordinators of the DES-MIIC were contacted to establish the list of approved internship sites for the MIIC DES within their geographical subdivision.</div></div><div><h3>Results</h3><div>We listed 244 approved training sites, of which 87 (35.7%) were in university hospitals. Depending on the region/subdivision, the number of approved training sites varied significantly. Internship sites within and outside of university hospitals were approved for the core-phase in 85% (74/87) and 63.7% (100/157) of cases, for the “development phase” in 94.3% (82/87) and 84.1% (132/157) of cases and for the consolidation phase 80.5% (70/87) and 52.2% (82/157) of cases, respectively. The vacancy rate for selection was lower in university hospitals than in general hospitals with ratios of 1.5 (89.3% vs. 61%), 1.8 (88.8% vs. 48.9%) and 1.6 (88,5% vs. 55.4%) - for respectively the core, development and consolidation phases.</div></div><div><h3>Conclusion</h3><div>Thirty-five percent of internship sites were located in University hospitals. Depending on the region/subdivision, the number of approved training sites for the DES-MIIC varies greatly. Half of internship positions are vacant outside of University hospitals, just as nearly half of training sites in these same hospitals lack approval for the “consolidation phase”.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 9","pages":"Pages 509-516"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144510119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chez les personnes atteintes d’un cancer actif et d’une maladie thromboembolique veineuse anticoagulée pendant au moins 6 mois, un traitement prolongé à dose réduite d’apixaban est-il efficace pour prévenir les récidives et diminuer le risque de saignement, comparativement à une dose complète ?","authors":"Luc Lanthier ,&nbsp;Geneviève Le Templier ,&nbsp;Alexandre Mutchmore ,&nbsp;Marc-Émile Plourde ,&nbsp;Michel Cauchon","doi":"10.1016/j.revmed.2025.06.011","DOIUrl":"10.1016/j.revmed.2025.06.011","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 9","pages":"Pages 566-567"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144513025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Une maladie d’Erdheim-Chester associée à une histiocytose à cellules de Langerhans : un cas d’une forme mixte","authors":"Houria Sahel ,&nbsp;Billel Merrouche ,&nbsp;Souad Bellaifa ,&nbsp;Nacima Djennane ,&nbsp;Zine Charef Amir ,&nbsp;Abdelkrim Talbi ,&nbsp;Ammar Maireche ,&nbsp;Radhia Ait Chalal ,&nbsp;Amine Habouchi","doi":"10.1016/j.revmed.2025.02.012","DOIUrl":"10.1016/j.revmed.2025.02.012","url":null,"abstract":"<div><h3>Introduction</h3><div>Langerhans cell histiocytosis and Erdheim-Chester disease are rare inflammatory myeloid neoplasms. They present characteristic clinical, histological and radiological signs. Their association is exceptional. We report a new observation.</div></div><div><h3>Observation</h3><div>A 47-year-old man presented with lesions of seborrheic dermatitis-like, intracranial hypertension, paralysis of the sixth cranial nerve, and central diabetes insipidus. The skin biopsy concluded that there was Langerhans cell histiocytosis. The bone scan showed metaphyseal-diaphyseal osteosclerotic lesions of the femur, tibia and humerus. The thoraco-abdomino-pelvic CT scan showed an aortic sheathing, suggesting Erdheim-Chester disease. The search for the <em>BRAF</em>^{<em>V600E</em>} mutation was negative. The patient was treated with oral corticosteroid therapy then with cladribine which allowed a good evolution.</div></div><div><h3>Conclusion</h3><div>We report an observation of a mixed form of histiocytosis associating Langerhans cell histiocytosis and Erdheim-Chester disease, with a diagnostic delay of ten years, and having responded well to treatment with cladribine.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 9","pages":"Pages 549-556"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gare au chaud lapin","authors":"L. Frisson ,&nbsp;F. Aboubakar ,&nbsp;G. Zorzi ,&nbsp;V. Roelants ,&nbsp;L. Pothen ,&nbsp;L. Bamps ,&nbsp;H. Yildiz ,&nbsp;A. Benyamine","doi":"10.1016/j.revmed.2025.05.014","DOIUrl":"10.1016/j.revmed.2025.05.014","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 9","pages":"Pages 560-562"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catatonie – À propos de quatre cas cliniques et revue de la littérature","authors":"Hadi Faiz ,&nbsp;Elise Reyal ,&nbsp;Benjamin Subran ,&nbsp;Jonathan London ,&nbsp;Emmanuel Le Guen ,&nbsp;Mailys Cohu ,&nbsp;Olivier Lidove","doi":"10.1016/j.revmed.2025.06.006","DOIUrl":"10.1016/j.revmed.2025.06.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Catatonia is a neuropsychiatric syndrome characterized by the presence of at least three out of the twelve following signs: stupor, catalepsy, waxy flexibility, mutism, negativism, posturing, mannerisms, stereotypies, agitation, grimacing, echolalia, and echopraxia. We will describe four cases of catatonia that occurred over one year in a single medicine department.</div></div><div><h3>Clinical cases</h3><div>All four patients were over 60 years old. The causes of catatonia were diverse: hemorrhagic shock occurring in the context of mixed dementia, schizoaffective disorder, a severe major depressive episode, and a depressive syndrome associated with Lewy body disease. Three out of four patients were treated with electroconvulsive therapy (ECT), and all evolved towards remission. The diagnoses were consistently established by a liaison psychiatrist.</div></div><div><h3>Discussion</h3><div>Before the recruitment of liaison psychiatrists in the institution, this diagnosis had not been considered in the department. The cause of catatonia can be psychiatric (75 to 80% of cases) and/or non-psychiatric (20 to 25% of cases). In two thirds of organic cases, it is a condition of the central nervous system. Symptomatic treatment with benzodiazepine allows for remission of symptoms in more than two thirds of cases. In the absence of response to benzodiazepines, treatment with electroconvulsive therapy is indicated. Catatonia can progress to death, following possible complications or in cases of severe dysautonomia (malignant catatonia).</div></div><div><h3>Conclusion</h3><div>Catatonia is underdiagnosed and undertreated. Despite a relatively high prevalence, well-defined diagnostic criteria, and a symptomatic treatment that is often very effective, the prognosis of catatonia can be poor in the absence of treatment. Psychiatrists should be consulted whenever there is doubt regarding a clinical presentation.</div></div>","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 9","pages":"Pages 542-548"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quatorze façons de cibler le lymphocyte B dans le traitement du lupus érythémateux systémique","authors":"Laurent Chiche ,&nbsp;Divi Cornec ,&nbsp;Guillaume Morel ,&nbsp;Noémie Jourde-Chiche","doi":"10.1016/j.revmed.2025.08.010","DOIUrl":"10.1016/j.revmed.2025.08.010","url":null,"abstract":"","PeriodicalId":54458,"journal":{"name":"Revue De Medecine Interne","volume":"46 9","pages":"Pages 503-508"},"PeriodicalIF":0.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}