Eurointervention最新文献

{"title":"Drug-eluting devices for lower limb peripheral arterial disease.","authors":"Yann Gouëffic, Marianne Brodmann, Koen Deloose, Maxime Dubosq-Lebaz, Joakim Nordanstig","doi":"10.4244/EIJ-D-23-01080","DOIUrl":"10.4244/EIJ-D-23-01080","url":null,"abstract":"<p><p>Peripheral arterial disease is the third leading cause of cardiovascular morbidity after coronary artery disease and stroke. Lower limb peripheral arterial disease commonly involves infrainguinal arteries, may impair walking ability (intermittent claudication) and may confer a significant risk of limb loss (chronic limb-threatening ischaemia), depending on the severity of ischaemia. Endovascular treatment has become the mainstay revascularisation option in both the femoropopliteal and the below-the-knee arterial segments. After crossing and preparing the lesion, treatment results in these arterial segments can be enhanced by using drug-coated devices (drug-eluting stents and drug-coated balloons) that mitigate the occurrence of restenosis. As for other medical devices, the use of drug-eluting devices is based on their demonstrated safety and efficacy profiles when applied in the distinct segments of the lower limb vasculature. In this state-of-the-art narrative review we provide an overview of the safety and efficacy of drug-coated devices when used in the femoropopliteal and below-the-knee arterial segments.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 18","pages":"e1136-e1153"},"PeriodicalIF":7.6,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11423351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is it time for a myocardial infarction approach to high- and intermediate-high-risk pulmonary embolism?","authors":"Marco Zuin, Gregory Piazza","doi":"10.4244/EIJ-D-24-00267","DOIUrl":"https://doi.org/10.4244/EIJ-D-24-00267","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 18","pages":"e1129-e1131"},"PeriodicalIF":7.6,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding our understanding on stent expansion.","authors":"Gabor G Toth, Goran Stankovic","doi":"10.4244/EIJ-E-24-00042","DOIUrl":"https://doi.org/10.4244/EIJ-E-24-00042","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 18","pages":"e1127-e1128"},"PeriodicalIF":7.6,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe aortic regurgitation: the limits of TAVI.","authors":"Victoria Delgado, Elena Díaz Peláez","doi":"10.4244/EIJ-E-24-00045","DOIUrl":"10.4244/EIJ-E-24-00045","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 17","pages":"e1051-e1052"},"PeriodicalIF":7.6,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous transvalvular microaxial flow pump is underused in infarct-related cardiogenic shock: pros and cons.","authors":"Thomas Engstrøm, Jasmine Melissa Madsen, Holger Thiele, Uwe Zeymer","doi":"10.4244/EIJ-E-24-00033","DOIUrl":"10.4244/EIJ-E-24-00033","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 17","pages":"e1059-e1061"},"PeriodicalIF":7.6,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic regurgitation: from mechanisms to management.","authors":"Andreas Baumbach, Kush P Patel, Tanja K Rudolph, Victoria Delgado, Hendrik Treede, Alexander R Tamm","doi":"10.4244/EIJ-D-23-00840","DOIUrl":"10.4244/EIJ-D-23-00840","url":null,"abstract":"<p><p>Aortic regurgitation (AR) is a common clinical disease associated with significant morbidity and mortality. Investigations based largely on non-invasive imaging are pivotal in discerning the severity of disease and its impact on the heart. Advances in technology have contributed to improved risk stratification and to our understanding of the pathophysiology of AR. Surgical aortic valve replacement is the predominant treatment. However, its use is limited to patients with an acceptable surgical risk profile. Transcatheter aortic valve implantation is an alternative treatment. However, this therapy remains in its infancy, and further data and experience are required. This review article on AR describes its prevalence, mechanisms, diagnosis and treatment.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 17","pages":"e1062-e1075"},"PeriodicalIF":7.6,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of transcatheter aortic valve implantation for native aortic valve regurgitation.","authors":"Robin Le Ruz, Lionel Leroux, Thibault Lhermusier, Thomas Cuisset, Eric Van Belle, Alain Dibie, Vincenzo Palermo, Didier Champagnac, Jean-François Obadia, Emmanuel Teiger, Patrick Ohlman, Didier Tchétché, Hervé Le Breton, Christophe Saint-Etienne, Pierre-Guillaume Piriou, Julien Plessis, Sylvain Beurtheret, Florence Du Chayla, Manon Leclère, Thierry Lefèvre, Jean-Philippe Collet, Hélène Eltchaninoff, Martine Gilard, Bernard Iung, Thibaut Manigold, Vincent Letocart, On Behalf Of Stop-As And France-Tavi Investigators","doi":"10.4244/EIJ-D-24-00339","DOIUrl":"10.4244/EIJ-D-24-00339","url":null,"abstract":"<p><strong>Background: </strong>Large datasets of transcatheter aortic valve implantation (TAVI) for pure aortic valve regurgitation (PAVR) are scarce.</p><p><strong>Aims: </strong>We aimed to report procedural safety and long-term clinical events (CE) in a contemporary cohort of PAVR patients treated with new-generation devices (NGD).</p><p><strong>Methods: </strong>Patients with grade III/IV PAVR enrolled in the FRANCE-TAVI Registry were selected. The primary safety endpoint was technical success (TS) according to Valve Academic Research Consortium 3 criteria. The co-primary endpoint was defined as a composite of mortality, heart failure hospitalisation and valve reintervention at last follow-up.</p><p><strong>Results: </strong>From 2015 to 2021, 227 individuals (64.3% males, median age 81.0 [interquartile range {IQR} 73.5-85.0] years, with EuroSCORE II 6.0% [IQR 4.0-10.9]) from 41 centres underwent TAVI with NGD, using either self-expanding (55.1%) or balloon-expandable valves (44.9%; p=0.50). TS was 85.5%, with a non-significant trend towards increased TS in high-volume activity centres. A second valve implantation (SVI) was needed in 8.8% of patients, independent of valve type (p=0.82). Device size was ≥29 mm in 73.0% of patients, post-procedure grade ≥III residual aortic regurgitation was rare (1.2%), and the permanent pacemaker implantation (PPI) rate was 36.0%. At 30 days, the incidences of mortality and reintervention were 8.4% and 3.5%, respectively. The co-primary endpoint reached 41.6% (IQR 34.4-49.6) at 1 year, increased up to 61.8% (IQR 52.4-71.2) at 4 years, and was independently predicted by TS, with a hazard ratio of 0.45 (95% confidence interval: 0.27-0.76); p=0.003.</p><p><strong>Conclusions: </strong>TAVI with NGD in PAVR patients is efficient and reasonably safe. Preventing the need for an SVI embodies the major technical challenge. Larger implanted valves may have limited this complication, outweighing the increased risk of PPI. Despite successful TAVI, PAVR patients experience frequent CE at long-term follow-up.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 17","pages":"e1076-e1085"},"PeriodicalIF":7.6,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11363660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical frequency domain imaging-guided versus intravascular ultrasound-guided percutaneous coronary intervention for acute coronary syndromes: the OPINION ACS randomised trial.","authors":"Hiromasa Otake, Takashi Kubo, Kiyoshi Hibi, Makoto Natsumeda, Masaru Ishida, Toru Kataoka, Tomofumi Takaya, Masamichi Iwasaki, Shinjo Sonoda, Toshiro Shinke, Gaku Nakazawa, Yu Takahashi, Tetsuya Ioji, Takashi Akasaka, Opinion Acs Investigators","doi":"10.4244/EIJ-D-24-00314","DOIUrl":"10.4244/EIJ-D-24-00314","url":null,"abstract":"<p><strong>Background: </strong>The clinical benefits of optical frequency domain imaging (OFDI)-guided percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) remain unclear.</p><p><strong>Aims: </strong>We sought to compare intravascular ultrasound (IVUS)- and OFDI-guided PCI in patients with ACS.</p><p><strong>Methods: </strong>OPINION ACS is a multicentre, prospective, randomised, non-inferiority trial that compared OFDI-guided PCI with IVUS-guided PCI using current-generation drug-eluting stents in ACS patients (n=158). The primary endpoint was in-stent minimum lumen area (MLA), assessed using 8-month follow-up OFDI.</p><p><strong>Results: </strong>Patients presented with ST-segment elevation myocardial infarction (55%), non-ST-segment elevation myocardial infarction (29%), or unstable angina pectoris (16%). PCI procedural success was achieved in all patients, with comparably low periprocedural complications rates in both groups. Immediately after PCI, the minimum stent area (p=0.096) tended to be smaller for OFDI versus IVUS guidance. Proximal stent edge dissection (p=0.012) and irregular protrusion (p=0.03) were significantly less frequent in OFDI-guided procedures than in IVUS-guided procedures. Post-PCI coronary flow, assessed using corrected Thrombolysis in Myocardial Infarction frame counts, was significantly better in the OFDI-guided group than in the IVUS-guided group (p<0.001). The least squares mean (95% confidence interval [CI]) in-stent MLA at 8 months was 4.91 (95% CI: 4.53-5.30) mm² and 4.76 (95% CI: 4.35-5.17) mm² in the OFDI- and IVUS-guided groups, respectively, demonstrating the non-inferiority of OFDI guidance (pnon-inferiority<0.001). The average neointima area tended to be smaller in the OFDI-guided group. The frequency of major adverse cardiac events was similar.</p><p><strong>Conclusions: </strong>Among ACS patients, OFDI-guided PCI and IVUS-guided PCI were equally safe and feasible, with comparable in-stent MLA at 8 months. OFDI guidance may be a potential option in ACS patients. This study was registered in the Japan Registry of Clinical Trials (jrct.niph.go.jp: jRCTs052190093).</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 17","pages":"e1086-e1097"},"PeriodicalIF":7.6,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new resorbable magnesium scaffold (DREAMS 3G): 12-month vasomotion results from the BIOMAG-I first-in-human study.","authors":"Michael Haude, Juan F Iglesias, Hector M Garcia-Garcia, Dimitrios Barlagiannis, Sophie Degrauwe, Gebremedhin Melaku, Solomon Beyene, Ron Waksman","doi":"10.4244/EIJ-D-24-00355","DOIUrl":"10.4244/EIJ-D-24-00355","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 17","pages":"e1118-e1120"},"PeriodicalIF":7.6,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stent sizing in imaging-guided percutaneous coronary intervention: potential benefits of a more cautious approach.","authors":"Tom Adriaenssens, Peter Sinnaeve","doi":"10.4244/EIJ-E-24-00049","DOIUrl":"10.4244/EIJ-E-24-00049","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 17","pages":"e1053-e1055"},"PeriodicalIF":7.6,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}