Eurointervention最新文献_第10页

Biolimus-coated versus paclitaxel-coated balloons for coronary in-stent restenosis (BIO ASCEND ISR): a randomised, non-inferiority trial. 治疗冠状动脉支架内再狭窄的Biolimus涂层球囊与紫杉醇涂层球囊（BIO ASCEND ISR）：随机、非劣效试验。

IF 7.6 1区医学

Eurointervention Pub Date : 2024-07-01 DOI: 10.4244/EIJ-D-24-00295

Yundai Chen, Lei Gao, Qin Qin, Jun Zhang, Shaobin Jia, Mingxing Wu, Yong He, Guosheng Fu, Jinghua Liu, Hui Chen, Qian Tong, Zaixin Yu, Jian An, Chunguang Qiu, Biao Xu, Yu Cao, Changqian Wang, Genshan Ma

{"title":"Biolimus-coated versus paclitaxel-coated balloons for coronary in-stent restenosis (BIO ASCEND ISR): a randomised, non-inferiority trial.","authors":"Yundai Chen, Lei Gao, Qin Qin, Jun Zhang, Shaobin Jia, Mingxing Wu, Yong He, Guosheng Fu, Jinghua Liu, Hui Chen, Qian Tong, Zaixin Yu, Jian An, Chunguang Qiu, Biao Xu, Yu Cao, Changqian Wang, Genshan Ma","doi":"10.4244/EIJ-D-24-00295","DOIUrl":"10.4244/EIJ-D-24-00295","url":null,"abstract":"Background: The treatment of in-stent restenosis (ISR) after drug-eluting stent (DES) implantation remains challenging in current clinical practice.Aims: The study was conducted to investigate a novel biolimus-coated balloon (BCB) for the treatment of coronary DES-ISR compared with the best-investigated paclitaxel-coated balloon (PCB).Methods: This was a prospective, multicentre, randomised, non-inferiority trial comparing a novel BCB with a clinically proven PCB for coronary DES-ISR. The primary endpoint was in-segment late lumen loss (LLL) at 9 months assessed by an independent core laboratory. Baseline and follow-up optical coherence tomography were performed in a prespecified subgroup of patients.Results: A total of 280 patients at 17 centres were randomised to treatment with a BCB (n=140) versus a PCB (n=140). At 9 months, LLL in the BCB group was 0.23±0.37 mm compared to 0.25±0.35 mm in the PCB group; the mean difference between the groups was -0.02 (95% confidence interval [CI]: -0.12 to 0.07) mm; p-value for non-inferiority<0.0001. Similar clinical outcomes were also observed for both groups at 12 months. In the optical coherence tomography substudy, the neointimal area at 9 months was 2.32±1.04 mm2 in the BCB group compared to 2.37±0.93 mm2 in the PCB group; the mean difference between the groups was -0.09 (95% CI: -0.94 to 0.76) mm2; p=non-significant.Conclusions: This head-to-head comparison of a novel BCB shows similar angiographic outcomes in the treatment of coronary DES-ISR compared with a clinically proven PCB. (ClinicalTrials.gov: NCT04733443).","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":"e806-e817"},"PeriodicalIF":7.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11200665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paclitaxel-coated balloons for vulnerable lipid-rich plaques. 紫杉醇涂层球囊用于治疗易损的富脂斑块。

IF 7.6 1区医学

Eurointervention Pub Date : 2024-07-01 DOI: 10.4244/EIJ-D-23-01073

Anna van Veelen, I Tarik Küçük, Hector M Garcia-Garcia, Federico H Fuentes, Yirga Kahsay, Ronak Delewi, Marcel A M Beijk, Alexander W den Hartog, Maik J Grundeken, M Marije Vis, José P S Henriques, Bimmer E P M Claessen

引用次数: 0

Predictors of target lesion failure after percutaneous coronary intervention with a drug-coated balloon for de novo lesions. 使用药物涂层球囊经皮冠状动脉介入治疗新发病变后靶病变失败的预测因素。

IF 7.6 1区医学

Eurointervention Pub Date : 2024-07-01 DOI: 10.4244/EIJ-D-23-01006

Tetsumin Lee, Takashi Ashikaga, Toshihiro Nozato, Yasutoshi Nagata, Masakazu Kaneko, Ryoichi Miyazaki, Toru Misawa, Yuta Taomoto, Shinichiro Okata, Masashi Nagase, Tomoki Horie, Mao Terui, Daigo Kachi, Yuki Odanaka, Kazuki Matsuda, Michihito Naito, Ayaka Koido, Taishi Yonetsu, Tetsuo Sasano

{"title":"Predictors of target lesion failure after percutaneous coronary intervention with a drug-coated balloon for de novo lesions.","authors":"Tetsumin Lee, Takashi Ashikaga, Toshihiro Nozato, Yasutoshi Nagata, Masakazu Kaneko, Ryoichi Miyazaki, Toru Misawa, Yuta Taomoto, Shinichiro Okata, Masashi Nagase, Tomoki Horie, Mao Terui, Daigo Kachi, Yuki Odanaka, Kazuki Matsuda, Michihito Naito, Ayaka Koido, Taishi Yonetsu, Tetsuo Sasano","doi":"10.4244/EIJ-D-23-01006","DOIUrl":"10.4244/EIJ-D-23-01006","url":null,"abstract":"Background: There are limited data about determinant factors of target lesion failure (TLF) in lesions after percutaneous coronary intervention (PCI) using a drug-coated balloon (DCB) for de novo coronary artery lesions, including optical coherence tomography (OCT) findings.Aims: The present study aims to investigate the associated factors of TLF in de novo coronary artery lesions with DCB treatment.Methods: We retrospectively enrolled 328 de novo coronary artery lesions in 328 patients who had undergone PCI with a DCB. All lesions had been treated without a stent, and both pre- and post-PCI OCT had been carried out. Patients were divided into two groups, with or without TLF, which was defined as a composite of culprit lesion-related cardiac death, myocardial infarction, and target lesion revascularisation, and the associated factors of TLF were assessed.Results: At the median follow-up period of 460 days, TLF events occurred in 31 patients (9.5%) and were associated with patients requiring haemodialysis (HD; 29.0% vs 10.8%), with a severely calcified lesion (median maximum calcium arc 215° vs 104°), and with the absence of OCT medial dissection (16.1% vs 60.9%) as opposed to those without TLF events. In Cox multivariable logistic regression analysis, HD (hazard ratio [HR]: 2.26, 95% confidence interval [CI]: 1.00-5.11; p=0.049), maximum calcium arc (per 90°, HR: 1.34, 95% CI: 1.05-1.72; p=0.02), and the absence of post-PCI medial dissection on OCT (HR: 8.24, 95% CI: 3.15-21.6; p<0.001) were independently associated with TLF.Conclusions: In de novo coronary artery lesions that received DCB treatment, factors associated with TLF were being on HD, the presence of a severely calcified lesion, and the absence of post-PCI medial dissection.","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 13","pages":"e818-e825"},"PeriodicalIF":7.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11200664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First-in-human implantation of a customised balloon-expandable valve into a dysfunctional Tendyne valve. 首次在人体中将定制的球囊扩张瓣膜植入功能障碍的 Tendyne 瓣膜。

IF 7.6 1区医学

Eurointervention Pub Date : 2024-07-01 DOI: 10.4244/EIJ-D-23-01034

Paolo Denti, Matteo Saccocci, Nicola Buzzatti, Edoardo Zancanaro, Franscesco Maisano

引用次数: 0

Angioplasty with drug-coated balloon catheters: the coming tide? 使用药物涂层球囊导管进行血管成形术：大潮将至？

IF 7.6 1区医学

Eurointervention Pub Date : 2024-07-01 DOI: 10.4244/EIJ-E-24-00035

Robert A Byrne, Rory Durand

引用次数: 0

Aggressive predilatation seeking medial dissection: a prerequisite for a drug-coated balloon-only strategy in de novo coronary lesions? 积极预扩张以寻求内侧夹层：在新生冠状动脉病变中采用药物涂层球囊策略的先决条件？