EurointerventionPub Date : 2026-05-21DOI: 10.4244/EIJ-D-26-00479
Ron Waksman, Asa Phichaphop
{"title":"Valve thrombosis or valve deterioration: what truly drives the prognosis?","authors":"Ron Waksman, Asa Phichaphop","doi":"10.4244/EIJ-D-26-00479","DOIUrl":"10.4244/EIJ-D-26-00479","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13207886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148018567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2026-05-21DOI: 10.4244/EIJCR-D-26-00026
Charlotte Burup Kristensen, Gintautas Bieliauskas, Jacob E Møller, Ole De Backer
{"title":"Transcatheter tricuspid valve replacement using a novel system in a patient with a right ventricular pacemaker lead.","authors":"Charlotte Burup Kristensen, Gintautas Bieliauskas, Jacob E Møller, Ole De Backer","doi":"10.4244/EIJCR-D-26-00026","DOIUrl":"https://doi.org/10.4244/EIJCR-D-26-00026","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2026-05-21DOI: 10.4244/EIJ-D-25-01370
Antonin Trimaille, Olivier Morel, Alberto Alperi, Gabriela Veiga-Fernandez, Luis Nombela-Franco, Victoria Vilalta, Antonio Munoz-Garcia, Jorge Nuche, Anna Franzone, Marina Urena, Lluis Asmarats, Ander Regueiro, Maria Del Trigo, Vincent Auffret, David Del Val, Vicenç Serra, Adrien Carmona, Pablo Avanzas, Victor Fradejas-Sastre, Ivan Sanchez, Michele Trichilo, Nicolas Maneiro, Maddalena Immobile Molaro, Quentin Fischer, Dabit Arzamendi, Eduardo Flores-Umanzor, Juan Francisco Oteo, Maxime Nolf, Fernando Alfonso, Pedro Díaz Pockels, Camil Elkadiri, Pedro Cepas-Guillén, Marisa Avvedimento, Josep Rodés-Cabau
{"title":"Prognostic value of early haemodynamic valve deterioration after TAVI.","authors":"Antonin Trimaille, Olivier Morel, Alberto Alperi, Gabriela Veiga-Fernandez, Luis Nombela-Franco, Victoria Vilalta, Antonio Munoz-Garcia, Jorge Nuche, Anna Franzone, Marina Urena, Lluis Asmarats, Ander Regueiro, Maria Del Trigo, Vincent Auffret, David Del Val, Vicenç Serra, Adrien Carmona, Pablo Avanzas, Victor Fradejas-Sastre, Ivan Sanchez, Michele Trichilo, Nicolas Maneiro, Maddalena Immobile Molaro, Quentin Fischer, Dabit Arzamendi, Eduardo Flores-Umanzor, Juan Francisco Oteo, Maxime Nolf, Fernando Alfonso, Pedro Díaz Pockels, Camil Elkadiri, Pedro Cepas-Guillén, Marisa Avvedimento, Josep Rodés-Cabau","doi":"10.4244/EIJ-D-25-01370","DOIUrl":"10.4244/EIJ-D-25-01370","url":null,"abstract":"<p><strong>Background: </strong>Early haemodynamic valve deterioration (HVD) was associated with worse clinical outcomes and bioprosthetic durability after transcatheter aortic valve implantation (TAVI) in a single-centre study.</p><p><strong>Aims: </strong>The aim of this study was to evaluate the incidence, predictors, and prognostic impact of early HVD in a large-scale TAVI population.</p><p><strong>Methods: </strong>We analysed the data from an international, multicentre registry including consecutive patients from 16 centres undergoing TAVI. Early HVD was defined as an increase of at least 10 mmHg in the mean transaortic gradient on echocardiography performed within the first three months after TAVI, compared with the discharge echocardiography. The primary endpoint was the valve-related long-term clinical efficacy according to the Valve Academic Research Consortium 3.</p><p><strong>Results: </strong>Among 7,392 patients, early HVD was observed in 231 patients (3.1%). Body mass index (adjusted odds ratio [aOR] per 5 kg/m<sup>2</sup> increase 1.15, 95% confidence interval [CI]: 1.02-1.30), prosthesis size <26 mm (aOR 1.96, 95% CI: 1.43-2.70), valve-in-valve procedure (aOR 2.76, 95% CI: 1.83-4.08), and the absence of anticoagulation at discharge (aOR 1.64, 95% CI: 1.22-2.22) were independent predictors of early HVD. After a median follow-up of 4 years (interquartile range 2-5), early HVD was independently associated with a lower valve-related long-term clinical efficacy (subdistribution hazard ratio [sHR] 0.42, 95% CI: 0.32-0.56), and a higher risk of stroke (sHR 2.32, 95% CI: 1.51-3.57), stage 2 or 3 (sHR 2.74, 95% CI: 2.10-3.57) or stage 3 bioprosthetic valve dysfunction (sHR 3.53, 95% CI: 2.15-5.79), and bioprosthetic valve failure (sHR 3.04, 95% CI: 2.06-4.52). Consistent findings were observed in a propensity score-matched cohort and in different sensitivity analyses.</p><p><strong>Conclusions: </strong>Early HVD was observed in 3.1% of patients and was associated with adverse clinical and haemodynamic outcomes after TAVI. These findings validate the clinical relevance of detecting early HVD and the necessity for further research to guide optimal management of these patients.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13207893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148018493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2026-05-20DOI: 10.4244/EIJ-D-26-00390
Matteo Casenghi, Ole De Backer, Chiara De Biase, Pasquale Paolisso, Emanuele Gallinoro, Yusuke Kobari, Arif Khokhar, Andrea Scotti, Alejandro Aruajo Adams, Luca Testa, Antonella Millin, Arturo Giordano, Nicola Corcione, Marc Vanderheyden, Sara Corradetti, Giuseppe Esposito, Jacopo Oreglia, Claudio Montalto, Marco Barbanti, Giuliano Costa, Stefano Cannata, Caterina Gandolfo, Federico De Marco, Elena Dipietro, Gian Paolo Ussia, Fabio Mangiacapra, Gabor Toth, Francesca Di Lenarda, Francesco De Felice, Vincenzo Cesario, Elisa Nicolini, Tommaso Piva, Attilio Leone, Andrea Berni, Marta Belmonte, Didier Tchetche, Azeem Latib, Francesco Bedogni, Emanuele Barbato
{"title":"Clinical and haemodynamic outcomes with contemporary intra- and supra-annular self-expanding valves: the multicentre international HERA-TAVI registry.","authors":"Matteo Casenghi, Ole De Backer, Chiara De Biase, Pasquale Paolisso, Emanuele Gallinoro, Yusuke Kobari, Arif Khokhar, Andrea Scotti, Alejandro Aruajo Adams, Luca Testa, Antonella Millin, Arturo Giordano, Nicola Corcione, Marc Vanderheyden, Sara Corradetti, Giuseppe Esposito, Jacopo Oreglia, Claudio Montalto, Marco Barbanti, Giuliano Costa, Stefano Cannata, Caterina Gandolfo, Federico De Marco, Elena Dipietro, Gian Paolo Ussia, Fabio Mangiacapra, Gabor Toth, Francesca Di Lenarda, Francesco De Felice, Vincenzo Cesario, Elisa Nicolini, Tommaso Piva, Attilio Leone, Andrea Berni, Marta Belmonte, Didier Tchetche, Azeem Latib, Francesco Bedogni, Emanuele Barbato","doi":"10.4244/EIJ-D-26-00390","DOIUrl":"10.4244/EIJ-D-26-00390","url":null,"abstract":"<p><strong>Background: </strong>Contemporary self-expanding transcatheter heart valves (THVs) differ in leaflet position and frame architecture. Comparative data between new-generation intra-annular (IA) and supra-annular (SA) platforms remain limited.</p><p><strong>Aims: </strong>We sought to compare 30-day and 1-year clinical and haemodynamic outcomes between contemporary intra-annular and supra-annular self-expanding THVs in a large multicentre real-world cohort.</p><p><strong>Methods: </strong>Consecutive patients undergoing transfemoral transcatheter aortic valve implantation with a Navitor/Navitor Vision (IA self-expanding valve [SEV]) or Evolut FX/FX+ (SA-SEV) between June 2021 and April 2025 were included. The primary endpoint was the composite of all-cause death, disabling stroke, or heart failure hospitalisation at 1 year. Propensity score matching (PSM) was performed to adjust for baseline differences.</p><p><strong>Results: </strong>Among 2,607 patients (IA-SEV: 1,604; SA-SEV: 1,003), PSM yielded 892 well-balanced pairs. Valve Academic Research Consortium 3 device success was achieved in 91.1% of IA-SEV patients and 90.9% of SA-SEV patients (p=0.868). Permanent pacemaker implantation was more frequent with IA-SEVs (22.1% vs 16.3%; p=0.007), whereas major or life-threatening bleeding was more common with SA-SEVs (4.2% vs 2.6%; p<0.001). At 1 year, the primary endpoint occurred in 12.6% of IA-SEV patients and 11.3% of SA-SEV patients (p=0.422) with no difference between groups in the time-to-event analysis (hazard ratio [HR] 1.01, 95% confidence interval [CI]: 0.77-1.33; p=0.916). The mean transvalvular gradients and rates of moderate or severe paravalvular leak remained low and similar between the two groups at 1 year. Findings were consistent in the unmatched cohort (HR 1.02, 95% CI: 0.81-1.31; p=0.835).</p><p><strong>Conclusions: </strong>In this large real-world registry, contemporary IA-SEVs and SA-SEVs demonstrated overall similar clinical outcomes and sustained haemodynamic performance at 1-year follow-up, despite differences in procedure-related endpoints between the groups.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13330125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2026-05-18DOI: 10.4244/EIJCR-D-26-00020
Mattia Basile, Borja Rivero Santana, Jon Zubiaur, Daniel Tebar, Guillermo Galeote Escalera, Santiago Jimenez Valero, Guillermo Galeote, Raúl Moreno, Alfonso Jurado-Román
{"title":"Bailout excimer laser coronary atherectomy for guidewire entrapment in a severely calcified left anterior descending artery complicated by dual perforation.","authors":"Mattia Basile, Borja Rivero Santana, Jon Zubiaur, Daniel Tebar, Guillermo Galeote Escalera, Santiago Jimenez Valero, Guillermo Galeote, Raúl Moreno, Alfonso Jurado-Román","doi":"10.4244/EIJCR-D-26-00020","DOIUrl":"https://doi.org/10.4244/EIJCR-D-26-00020","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2026-05-18DOI: 10.4244/EIJCR-D-26-00022
Piotr Foszcz, Timm Ubben, Da-Un Chung, Katharina Veliqi, Adrian Springer, Yusuf Nejahsie, Eike Tigges
{"title":"When a new murmur appears: the left-to-right dilemma - management of iatrogenic ventricular septal defect after transcatheter aortic valve implantation.","authors":"Piotr Foszcz, Timm Ubben, Da-Un Chung, Katharina Veliqi, Adrian Springer, Yusuf Nejahsie, Eike Tigges","doi":"10.4244/EIJCR-D-26-00022","DOIUrl":"https://doi.org/10.4244/EIJCR-D-26-00022","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2026-05-18DOI: 10.4244/EIJCR-D-26-00021
Juan F Bulnes, Daniëlle M Muijs, Wijnand K den Dekker
{"title":"Successful retrieval of a calcified embolus from the left main using a stent retriever after surgical aortic valve replacement.","authors":"Juan F Bulnes, Daniëlle M Muijs, Wijnand K den Dekker","doi":"10.4244/EIJCR-D-26-00021","DOIUrl":"https://doi.org/10.4244/EIJCR-D-26-00021","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2026-05-18DOI: 10.4244/EIJCR-D-26-00025
Giuliana Corna, Ignacio Miguel Seropian, Sebastian Piñel, Cristian Maximiliano Garmendia, Martin Denicolai, Rocio Isabel Lopez, Fernando Cohen, Alejandro Diego Fernández, Carla Romina Agatiello
{"title":"Percutaneous management of upward migration of an inferior vena cava prosthesis during implantation.","authors":"Giuliana Corna, Ignacio Miguel Seropian, Sebastian Piñel, Cristian Maximiliano Garmendia, Martin Denicolai, Rocio Isabel Lopez, Fernando Cohen, Alejandro Diego Fernández, Carla Romina Agatiello","doi":"10.4244/EIJCR-D-26-00025","DOIUrl":"https://doi.org/10.4244/EIJCR-D-26-00025","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}