EurointerventionPub Date : 2025-03-17DOI: 10.4244/EIJ-E-24-00072
Rocco Antonio Montone, Andrea Caffè, Keisuke Yasumura, Annapoorna Kini
{"title":"Routine diagnosis of ANOCA/INOCA: pros and cons.","authors":"Rocco Antonio Montone, Andrea Caffè, Keisuke Yasumura, Annapoorna Kini","doi":"10.4244/EIJ-E-24-00072","DOIUrl":"10.4244/EIJ-E-24-00072","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 6","pages":"e293-e295"},"PeriodicalIF":7.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-03-17DOI: 10.4244/EIJ-E-25-00005
Javier Escaned, Luca Paolucci
{"title":"Unveiling the coronary acetylcholine test: can it help us predict future cardiovascular events?","authors":"Javier Escaned, Luca Paolucci","doi":"10.4244/EIJ-E-25-00005","DOIUrl":"10.4244/EIJ-E-25-00005","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 6","pages":"e288-e289"},"PeriodicalIF":7.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-03-03DOI: 10.4244/EIJ-E-24-00061
Martin Andreas, Philipp Emmanuel Bartko, Andreas Zirlik
{"title":"CIED and tricuspid regurgitation - a LEADing problem?","authors":"Martin Andreas, Philipp Emmanuel Bartko, Andreas Zirlik","doi":"10.4244/EIJ-E-24-00061","DOIUrl":"10.4244/EIJ-E-24-00061","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e245-e246"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-03-03DOI: 10.4244/EIJ-D-23-01033
Björn Goebel, Philipp Lurz, Thomas Schmitz, Raffi Bekeredjian, Georg Nickenig, Helge Mollmann, Ralph Stephan von Bardeleben, Alexander Schmeisser, Megan Heitkemper, Iskandar Atmowihardjo, Rodrigo Estévez-Loureiro, Erwan Donal
{"title":"Outcomes of tricuspid transcatheter edge-to-edge repair in subjects with endocardial leads.","authors":"Björn Goebel, Philipp Lurz, Thomas Schmitz, Raffi Bekeredjian, Georg Nickenig, Helge Mollmann, Ralph Stephan von Bardeleben, Alexander Schmeisser, Megan Heitkemper, Iskandar Atmowihardjo, Rodrigo Estévez-Loureiro, Erwan Donal","doi":"10.4244/EIJ-D-23-01033","DOIUrl":"10.4244/EIJ-D-23-01033","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter edge-to-edge repair (TEER) using the TriClip tricuspid valve repair system has emerged as a therapy for tricuspid regurgitation (TR). Patients with TR undergoing TEER commonly present with an endocardial lead across the tricuspid valve (TV).</p><p><strong>Aims: </strong>We sought to examine the effectiveness and safety of tricuspid TEER (T-TEER) in subjects with endocardial leads in the bRIGHT EU Post-Approval Study (PAS).</p><p><strong>Methods: </strong>The bRIGHT EU PAS is a prospective, single-arm, open-label, multicentre, post-market registry conducted at 26 sites in Europe. Echocardiographic assessments of endocardial lead placement, interaction, and TR grade were performed at a core laboratory.</p><p><strong>Results: </strong>Of the 511 enrolled subjects, a total of 110 had an endocardial lead, and in 80.7% of these subjects, TR was at least partially related to the lead. At 30 days, 71% of subjects with endocardial leads had TR of moderate or less. The percentage of subjects with endocardial leads categorised as New York Heart Association Functional Class I-II increased from 17% at baseline to 75% at 30 days (p<0.0001), and quality of life with the Kansas City Cardiomyopathy Questionnaire showed a mean improvement of 20±24 points from baseline to 30 days (p<0.0001). T-TEER was safe in subjects with endocardial leads, with similar rates of events, including TV reintervention/reoperation and TV surgery, to those in subjects without leads. No reports of lead malfunction were reported.</p><p><strong>Conclusions: </strong>In the bRIGHT EU PAS, T-TEER using the TriClip system was safe and effective in severe TR subjects with an endocardial lead across the TV.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e253-e261"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transcatheter annuloplasty with the K-Clip system for tricuspid regurgitation: one-year results from the TriStar study.","authors":"Xiaochun Zhang, Qinchun Jin, Wei Li, Cuizhen Pan, Kefang Guo, Xue Yang, Weidong Li, Guangyuan Song, Jiangfang Luo, Jie Li, Xianbao Liu, Shasha Chen, Lei Zhang, Dandan Chen, Shiqiang Hou, Juying Qian, Jianan Wang, Daxin Zhou, Junbo Ge","doi":"10.4244/EIJ-D-24-00591","DOIUrl":"10.4244/EIJ-D-24-00591","url":null,"abstract":"<p><strong>Background: </strong>Despite the fact that morbidity and mortality rates significantly increase with tricuspid regurgitation (TR) severity, limited treatment options are available for treating severe TR.</p><p><strong>Aims: </strong>The single-arm, multicentre, prospective Confirmatory Clinical Study of Treating Tricuspid Regurgitation With K-Clip TM Transcatheter Annuloplasty System (TriStar) evaluated the 1-year outcomes of the novel transcatheter K-Clip annuloplasty system in treating secondary TR.</p><p><strong>Methods: </strong>Between May 2022 and October 2022, patients with ≥severe secondary TR despite optimal medical therapy at 11 centres in China were deemed candidates for transcatheter tricuspid repair by the local Heart Team and a multidisciplinary screening committee. Echocardiographic parameters, clinical and quality-of-life measures, and major adverse events were collected at 1 year.</p><p><strong>Results: </strong>Ninety-six patients were enrolled (mean age 72.6±7.0 years, 60.4% female, mean TRI-SCORE 5.4±2.1). The technical success rate was 97.9%. At 1 year, echocardiographic follow-up showed an average reduction in the annular septolateral diameter of 11.3% (41.9 mm vs 37.1 mm; p<0.01), compared with baseline, with marked right ventricular remodelling. A total of 82.5% of patients had ≤moderate TR, and 97.7% had a ≥1 grade reduction. Patients experienced significant clinical improvements in New York Heart Association Functional Class I/II (32.6% to 96.5%; p<0.001), the 6-minute walk distance increased by 31.9±71.8 m (p<0.001), and the overall Kansas City Cardiomyopathy Questionnaire score increased by 7.6±17.7 points (p<0.001). Neither cardiovascular death nor reintervention were recorded at the 30-day or 1-year follow-up, while severe bleeding requiring further treatment was noted in 5 patients at 1 year. The Kaplan-Meier estimates of survival and freedom from heart failure rehospitalisation were 97.8% and 95.1%, respectively, at 1 year.</p><p><strong>Conclusions: </strong>The 1-year experience using the K-Clip tricuspid annuloplasty system demonstrated high survival and low rehospitalisation rates with durable TR reduction and clinical benefits in functional status and quality-of-life outcomes.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e262-e271"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-03-03DOI: 10.4244/EIJ-E-25-00006
Georg Nickenig, Johanna Vogelhuber
{"title":"Tricuspid annuloplasty: a piece of the puzzle or the whole picture?","authors":"Georg Nickenig, Johanna Vogelhuber","doi":"10.4244/EIJ-E-25-00006","DOIUrl":"10.4244/EIJ-E-25-00006","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e247-e249"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-03-03DOI: 10.4244/EIJ-E-24-00074
Mohamed Abdel-Wahab, Oliver Dumpies
{"title":"Access site closure after TAVI: invincible sutures.","authors":"Mohamed Abdel-Wahab, Oliver Dumpies","doi":"10.4244/EIJ-E-24-00074","DOIUrl":"10.4244/EIJ-E-24-00074","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e250-e252"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-03-03DOI: 10.4244/EIJ-D-24-00741
Giuliano Costa, Thomas Pilgrim, Francesco Saia, Flavio Luciano Ribichini, Caterina Gandolfo, Azeem Latib, John G Webb, Mohamed Abdel-Wahab, Darren Mylotte, Marco Barbanti, For The Opera-Tavi
{"title":"Balloon-expandable SAPIEN 3 Ultra valve in intermediate sizing zones: insights from the OPERA-TAVI registry.","authors":"Giuliano Costa, Thomas Pilgrim, Francesco Saia, Flavio Luciano Ribichini, Caterina Gandolfo, Azeem Latib, John G Webb, Mohamed Abdel-Wahab, Darren Mylotte, Marco Barbanti, For The Opera-Tavi","doi":"10.4244/EIJ-D-24-00741","DOIUrl":"10.4244/EIJ-D-24-00741","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e282-e284"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-03-03DOI: 10.4244/EIJ-D-24-00120
David Grundmann, Won Kim, Caroline Kellner, Matti Adam, Daniel Braun, Alexander R Tamm, Max Meertens, Christian W Hamm, Sabine Bleiziffer, Jonas Gmeiner, Alexander Sedaghat, David Leistner, Matthias Renker, Hendrik Wienemann, Efstratios Charitos, Marie Linnemann, Tobias Lerchner, Benjamin Juri, Mostafa Salem, Roman Benetti-Lehmann, Henryk Dreger, Alina Goßling, Awesta Nahif, Lenard Conradi, Niklas Schofer, Andreas Schäfer, Jasmin Popara, Misumasa Sudo, Smita Scholtz, Ralph Stephan von Bardeleben, Marc Vorpahl, Derk Frank, Tanja K Rudolph, Moritz Seiffert
{"title":"A propensity-matched comparison of plug- versus suture-based vascular closure after TAVI.","authors":"David Grundmann, Won Kim, Caroline Kellner, Matti Adam, Daniel Braun, Alexander R Tamm, Max Meertens, Christian W Hamm, Sabine Bleiziffer, Jonas Gmeiner, Alexander Sedaghat, David Leistner, Matthias Renker, Hendrik Wienemann, Efstratios Charitos, Marie Linnemann, Tobias Lerchner, Benjamin Juri, Mostafa Salem, Roman Benetti-Lehmann, Henryk Dreger, Alina Goßling, Awesta Nahif, Lenard Conradi, Niklas Schofer, Andreas Schäfer, Jasmin Popara, Misumasa Sudo, Smita Scholtz, Ralph Stephan von Bardeleben, Marc Vorpahl, Derk Frank, Tanja K Rudolph, Moritz Seiffert","doi":"10.4244/EIJ-D-24-00120","DOIUrl":"10.4244/EIJ-D-24-00120","url":null,"abstract":"<p><strong>Background: </strong>Vascular access site complications are associated with increased morbidity and mortality after transcatheter aortic valve implantation (TAVI). Current results comparing strategies with plug- (P-VCD; MANTA) and suture-based vascular closure devices (S-VCD; Perclose ProGlide) remain inconsistent.</p><p><strong>Aims: </strong>It was our aim to assess the incidence of access-related vascular complications after P-VCD or S-VCD strategies after transfemoral TAVI.</p><p><strong>Methods: </strong>The Plug or sUture based vascuLar cloSurE after TAVI (PULSE) registry retrospectively evaluated 10,120 consecutive patients who had undergone transfemoral TAVI at 10 centres from 2016 to 2021. A propensity score was used to match 900 P-VCD patients with 1,800 S-VCD patients in a 1:2 fashion. The primary outcome measures were major and minor access-related vascular complications at the primary access site, adjudicated according to Valve Academic Research Consortium 3 definitions.</p><p><strong>Results: </strong>The median age was 81.8 years, 46.4% of patients were female, and the median European System for Cardiac Operative Risk Evaluation II was 3.50%. In matched P-VCD and S-VCD groups, large-bore access-related complications occurred in 14.9% vs 10.3% (p<0.001; major: 3.6% vs 4.6%; p=0.218; minor: 11.3% vs 5.8%; p<0.001) of patients. Bleeding accounted for most of these complications (9.6% vs 7.2%; p=0.028) and was treated with endovascular balloon inflation (5.4% vs 2.6%; p<0.001), stent implantation (4.7% vs 0.7%; p<0.001) or surgical repair (0.7% vs 1.7%; p=0.03).</p><p><strong>Conclusions: </strong>P-VCD were associated with higher rates of primary access-related vascular complications, driven by minor complications, compared to S-VCD. Endovascular treatment was more common after P-VCD failure.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e272-e281"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}