EurointerventionPub Date : 2024-08-05DOI: 10.4244/EIJ-D-24-00090
Julio I Farjat-Pasos, Rishi Puri, Omar Abdul-Jawad Altisent, Francesco Giannini, Gabriela Albert, Juan Del Portillo, Josep Rodés-Cabau, Can Manh Nguyen, Jean-Michel Paradis
{"title":"A-Flux: a novel self-expanding coronary sinus reducer for refractory angina.","authors":"Julio I Farjat-Pasos, Rishi Puri, Omar Abdul-Jawad Altisent, Francesco Giannini, Gabriela Albert, Juan Del Portillo, Josep Rodés-Cabau, Can Manh Nguyen, Jean-Michel Paradis","doi":"10.4244/EIJ-D-24-00090","DOIUrl":"10.4244/EIJ-D-24-00090","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":"e948-e950"},"PeriodicalIF":7.6,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of morphofunctional assessment with quantitative flow ratio and optical coherence tomography in patients with acute coronary syndromes.","authors":"Yuto Osumi, Hiroyuki Kawamori, Takayoshi Toba, Takashi Hiromasa, Daichi Fujimoto, Shunsuke Kakizaki, Koichi Nakamura, Tomoyo Hamana, Hiroyuki Fujii, Satoru Sasaki, Seigo Iwane, Tetsuya Yamamoto, Shota Naniwa, Yuki Sakamoto, Koshi Matsuhama, Yuta Fukuishi, Amane Kozuki, Junya Shite, Tomofumi Takaya, Akihiko Ishida, Masamichi Iwasaki, Ken-Ichi Hirata, Hiromasa Otake","doi":"10.4244/EIJ-D-23-01043","DOIUrl":"10.4244/EIJ-D-23-01043","url":null,"abstract":"<p><strong>Background: </strong>Combining morphological and physiological evaluations might improve the risk stratification of patients who undergo percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) culprit lesions.</p><p><strong>Aims: </strong>We aimed to investigate the clinical utility of morphofunctional evaluation after PCI for identifying ACS patients with increased risk of subsequent clinical events.</p><p><strong>Methods: </strong>We retrospectively studied 298 consecutive ACS patients who had undergone optical coherence tomography (OCT)-guided PCI. We performed OCT-based morphological analysis and quantitative flow ratio (QFR)-based physiological assessment immediately after PCI. The non-culprit segment (NCS) was defined as the most stenotic untreated segment in the culprit vessel. The primary outcome was target vessel failure (TVF), a composite of cardiac death, target vessel-related myocardial infarction, and ischaemia-driven target vessel revascularisation.</p><p><strong>Results: </strong>During a median follow-up period of 990 days, 42 patients experienced TVF. Cox regression analysis revealed that the presence of thin-cap fibroatheroma (TCFA) in the NCS and a low post-PCI QFR, or the presence of TCFA in the NCS and a high ΔQFR in the NCS (QFR<sub>NCS</sub>), were independently associated with TVF. The subgroup with TCFA in the NCS and a low post-PCI QFR had a significantly higher incidence of TVF (75%) than the other subgroups, and those with TCFA in the NCS and a high ΔQFR<sub>NCS</sub> had a significantly higher incidence of TVF (86%) than the other subgroups. The integration of TCFA in NCS, post-PCI QFR, and ΔQFR<sub>NCS</sub> with traditional risk factors significantly enhanced the identification of subsequent TVF cases.</p><p><strong>Conclusions: </strong>Combining post-PCI OCT and QFR evaluation may enhance risk stratification for ACS patients after successful PCI, particularly in predicting subsequent TVF.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 15","pages":"e927-e936"},"PeriodicalIF":7.6,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141890959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2024-08-05DOI: 10.4244/EIJ-D-24-00423
Aloke Finn, Renu Virmani, Bernardo Cortese
{"title":"Letter: Biological differences of three paclitaxel- and sirolimus-coated balloons on coronary lesions in a rabbit model.","authors":"Aloke Finn, Renu Virmani, Bernardo Cortese","doi":"10.4244/EIJ-D-24-00423","DOIUrl":"10.4244/EIJ-D-24-00423","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 15","pages":"e954"},"PeriodicalIF":7.6,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141890961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2024-08-05DOI: 10.4244/EIJ-E-24-00039
Francesco Prati, Laura Gatto
{"title":"Work in progress: OCT-guided coronary interventions in the acute setting.","authors":"Francesco Prati, Laura Gatto","doi":"10.4244/EIJ-E-24-00039","DOIUrl":"10.4244/EIJ-E-24-00039","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 15","pages":"e910-e911"},"PeriodicalIF":7.6,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2024-08-05DOI: 10.4244/EIJ-D-24-00249
Luping He, Sining Hu, Chen Zhao, Yini Wang, Ziqian Weng, Yuhan Qin, Xue Feng, Huai Yu, Lulu Li, Yishuo Xu, Dirui Zhang, Yue Zhu, Yan Zuo, Wei Hao, Jianlin Ma, Ming Zeng, Boling Yi, Ning Wang, Yanli Sun, Zhanqun Gao, Ekaterina Koniaeva, Diler Mohammad, Jingbo Hou, Gary S Mintz, Haibo Jia, Bo Yu
{"title":"Five-year follow-up of OCT-guided percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction.","authors":"Luping He, Sining Hu, Chen Zhao, Yini Wang, Ziqian Weng, Yuhan Qin, Xue Feng, Huai Yu, Lulu Li, Yishuo Xu, Dirui Zhang, Yue Zhu, Yan Zuo, Wei Hao, Jianlin Ma, Ming Zeng, Boling Yi, Ning Wang, Yanli Sun, Zhanqun Gao, Ekaterina Koniaeva, Diler Mohammad, Jingbo Hou, Gary S Mintz, Haibo Jia, Bo Yu","doi":"10.4244/EIJ-D-24-00249","DOIUrl":"10.4244/EIJ-D-24-00249","url":null,"abstract":"<p><strong>Background: </strong>Compared with intravascular ultrasound guidance, there is limited evidence for optical coherence tomography (OCT) guidance during primary percutaneous coronary intervention (pPCI) in ST-segment elevation myocardial infarction (STEMI) patients.</p><p><strong>Aims: </strong>We investigated the role of OCT in guiding a reperfusion strategy and improving the long-term prognosis of STEMI patients.</p><p><strong>Methods: </strong>All patients who were diagnosed with STEMI and who underwent pPCI between January 2017 and December 2020 were enrolled and divided into OCT-guided versus angiography-guided cohorts. They had routine follow-up for up to 5 years or until the time of the last known contact. All-cause death and cardiovascular death were designated as the primary and secondary endpoints, respectively.</p><p><strong>Results: </strong>A total of 3,897 patients were enrolled: 2,696 (69.2%) with OCT guidance and 1,201 (30.8%) with angiographic guidance. Patients in the OCT-guided cohort were less often treated with stenting during pPCI (62.6% vs 80.2%; p<0.001). The 5-year cumulative rates of all-cause mortality and cardiovascular mortality in the OCT-guided cohort were 10.4% and 8.0%, respectively, significantly lower than in the angiography-guided cohort (19.0% and 14.1%; both log-rank p<0.001). All 4 multivariate models showed that OCT guidance could significantly reduce 5-year all-cause mortality (hazard ratio [HR] in model 4: 0.689, 95% confidence interval [CI]: 0.551-0.862) and cardiovascular mortality (HR in model 4: 0.692, 95% CI: 0.536-0.895). After propensity score matching, the benefits of OCT guidance were consistent in terms of all-cause mortality (HR: 0.707, 95% CI: 0.548-0.913) and cardiovascular mortality (HR: 0.709, 95% CI: 0.526-0.955).</p><p><strong>Conclusions: </strong>Compared with angiography alone, OCT guidance may change reperfusion strategies and lead to better long-term survival in STEMI patients undergoing pPCI. Findings in the current observational study should be further corroborated in randomised trials.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 15","pages":"e937-e947"},"PeriodicalIF":7.6,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141890957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2024-08-05DOI: 10.4244/EIJ-E-24-00013
Gregg W Stone, Oludamilola Akinmolayemi, Rod H Stables
{"title":"Is bivalirudin ready for a comeback? Pros and cons.","authors":"Gregg W Stone, Oludamilola Akinmolayemi, Rod H Stables","doi":"10.4244/EIJ-E-24-00013","DOIUrl":"10.4244/EIJ-E-24-00013","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"20 15","pages":"e912-e914"},"PeriodicalIF":7.6,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11287373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141890960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}