Eurointervention最新文献

{"title":"The heterogeneity of response to direct oral anticoagulants in patients with hypoattenuating leaflet thickening.","authors":"Ali Husain, Julius Jelisejevas, John King Khoo, Jasem Althekrallah, Noah Tregobov, Sophie Offen, Kevin Millar, Jonathon A Leipsic, David Meier, Stephanie L Sellers, John G Webb","doi":"10.4244/EIJ-D-24-00461","DOIUrl":"10.4244/EIJ-D-24-00461","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 14","pages":"e827-e828"},"PeriodicalIF":9.5,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12285416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DAPT de-escalation post-ACS: a new rule or just a new option? Lessons from the 4D-ACS trial.","authors":"Thomas Cuisset, Guillaume Cayla","doi":"10.4244/EIJ-E-25-00023","DOIUrl":"10.4244/EIJ-E-25-00023","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":"e772-e773"},"PeriodicalIF":7.6,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12285391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of intracoronary supersaturated oxygen therapy on microvascular obstruction and infarct size in patients with acute anterior myocardial infarction.","authors":"Tobias König, Dominik Berliner, Johanna Diekmann, Muharrem Akin, Tobias Pfeffer, Carolina Sanchez Martinez, Vera Garcheva, Frank M Bengel, Johann Bauersachs, Andreas Schäfer","doi":"10.4244/EIJ-D-25-00034","DOIUrl":"10.4244/EIJ-D-25-00034","url":null,"abstract":"<p><strong>Background: </strong>Final infarct size (FIS) and microvascular obstruction (MVO) are associated with heart failure hospitalisations and mortality in patients with acute myocardial infarction (AMI). Interventions beyond primary percutaneous coronary intervention (PCI) to reduce FIS are needed. Supersaturated oxygen (SSO₂) therapy demonstrated reduced FIS in clinical trials.</p><p><strong>Aims: </strong>We aimed to investigate whether routine use of SSO₂ reduces FIS and MVO in clinical practice.</p><p><strong>Methods: </strong>Intracoronary SSO₂ was delivered for 60 minutes after successful primary PCI in patients with anterior AMI. Results from 20 SSO₂ patients were compared with those from 20 similar non-SSO₂ AMI patients. Multimodal imaging including single-photon emission computed tomography (SPECT), fibroblast activation protein inhibitor positron emission tomography (FAPI-PET), and cardiac magnetic resonance imaging (CMR) was performed to assess left ventricular function, FIS, area at risk, extent of myocardial fibroblast activation, myocardial salvage, and MVO.</p><p><strong>Results: </strong>The two groups did not significantly differ regarding sex, age, weight, hypertension, dyslipidaemia, smoking and diabetes status, prehospital cardiac arrest, door-to-balloon time, Thrombolysis in Myocardial Infarction flow before and after PCI, or renal function (p>0.1 for each) and had comparable area at risk by CMR and FAPI-PET. SSO₂ patients showed lower FIS determined by CMR (SSO₂: 20% vs non-SSO₂: 32%; p<0.001) and SPECT (SSO₂: 16% vs non-SSO₂: 29%; p=0.014). Myocardial salvage was higher in SSO₂ patients (50% vs 28%; p=0.002). MVO occurred less often and was less extreme under SSO₂ therapy.</p><p><strong>Conclusions: </strong>SSO₂ therapy was associated with significantly reduced microvascular obstruction and FIS in patients with anterior AMI in clinical routine practice.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 14","pages":"e810-e819"},"PeriodicalIF":9.5,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12285395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factor XI inhibition for ACS patients: premises and prospects.","authors":"Renato D Lopes, Alexander C Fanaroff","doi":"10.4244/EIJ-D-24-00943","DOIUrl":"10.4244/EIJ-D-24-00943","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 14","pages":"e776-e777"},"PeriodicalIF":9.5,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12285381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra- versus supra-annular self-expanding transcatheter heart valves in small aortic annuli.","authors":"Masanori Yamamoto, Toshinobu Ryuzaki, Hirofumi Hioki, Ai Kagase, Shinichi Shirai, Yohei Ohno, Fumiaki Yashima, Toru Naganuma, Masahiro Yamawaki, Yusuke Watanabe, Futoshi Yamanaka, Kazuki Mizutani, Masahiko Noguchi, Masaki Izumo, Kensuke Takagi, Masahiko Asami, Hiroshi Ueno, Hidetaka Nishina, Hiroto Suzuyama, Kazumasa Yamasaki, Kenji Nishioka, Daisuke Hachinohe, Yasushi Fuku, Toshiaki Otsuka, Kentaro Hayashida, On Behalf Of The Ocean-Tavi Investigators","doi":"10.4244/EIJ-D-24-00966","DOIUrl":"10.4244/EIJ-D-24-00966","url":null,"abstract":"<p><strong>Background: </strong>Clinical data are scarce comparing supra-annular self-expanding valves (SA-SEVs) and intra-annular (IA)-SEVs after transcatheter aortic valve implantation (TAVI), particularly in patients with a small aortic annulus (SAA).</p><p><strong>Aims: </strong>We aimed to compare early clinical outcomes, including echocardiographic parameters, between the latest generation of IA-SEV and SA-SEV after TAVI in patients with SAA.</p><p><strong>Methods: </strong>Focused on patients with SAA, defined as an annulus area ≤430 mm², the data of 919 patients who underwent TAVI with an IA-SEV (n=518, Navitor) or an SA-SEV (n=401, Evolut FX) were retrospectively extracted. Differences in valve design on postprocedural results were investigated between the two groups and in the propensity score-matched (PSM) cohort.</p><p><strong>Results: </strong>The postprocedural effective orifice area (EOA), indexed EOA, and mean pressure gradient (mPG) were similar in the overall cohort between the two groups (allp>0.05), whereas the mPG was higher with IA-SEVs than with SA-SEVs (8.74±5.01 mmHg vs 7.84±4.43 mmHg; p=0.049) after PSM (n=219 patients/group). There were no significant differences in the incidence of severe prosthesis-patient mismatch (1.9% vs 0.9%; p=0.405) or paravalvular leakage ≥mild (34.1% vs 42.2%; p=0.084) between the 2 groups in the PSM cohort. The rates of technical success (95.9% vs 95.8%), device success at discharge (91.3% vs 87.8%), and in-hospital death (1.4% vs 0.5%) were comparable in the overall cohort (allp>0.05). These results were not changed in the PSM cohort (allp>0.05).</p><p><strong>Conclusions: </strong>The latest-generation IA-SEV and SA-SEV demonstrated similar clinical results except for a few echocardiographic findings after TAVI in patients with SAA.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e749-e757"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravascular lithotripsy for proximal cap ambiguity in percutaneous coronary intervention for chronic total occlusions: the \"stone whisper\" technique.","authors":"Maximilian Will, Gregor Leibundgut, Konstantin Schwarz","doi":"10.4244/EIJ-D-24-01102","DOIUrl":"10.4244/EIJ-D-24-01102","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e769-e770"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current and future applications of robotics in structural heart interventions.","authors":"Xiang Chen, Giulio Russo, Mi Chen, Zhu Da, Xiangbin Pan, Yan Wang, Edwin Ho, Emiliano Votta, Paolo Denti, Didier Tchétché, Azeem Latib, Maurizio Taramasso","doi":"10.4244/EIJ-D-24-01003","DOIUrl":"10.4244/EIJ-D-24-01003","url":null,"abstract":"<p><p>Robotics entered the cardiovascular field in the late 1990s with a robot-assisted coronary artery bypass graft. Since then, the use of robots has become a common part of cardiovascular surgery in several types of interventions. The experience in transcatheter interventions has been slower, and the application of robotics to percutaneous coronary interventions has shown some encouraging results but also some technical limitations. Following the growth of structural heart interventions, attention has recently switched to the potential application of robotics in this field. So far, several cases have been performed in animal models and only a few cases in humans. The opportunity to perform a procedure (almost) without any X-ray exposure or lead garments is extremely attractive, especially for operators. Alongside these, there are several further potential advantages, but there are also many challenges to overcome. The integration of artificial intelligence and machine learning in the near future might further contribute to improve the performance of future generations of robots. In this review, the current and future applications of robotics in structural heart interventions and transoesophageal echocardiography will be discussed, together with the potential advantages, challenges and future perspectives.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e727-e736"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antithrombotic strategies after TAVI in light of cerebral microembolism.","authors":"George Dangas, Johny Nicolas","doi":"10.4244/EIJ-E-25-00027","DOIUrl":"10.4244/EIJ-E-25-00027","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e716-e717"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colchicine benefits are overestimated and current recommendations are too strong: pros and cons.","authors":"Kevin R Bainey, Xavier Rossello","doi":"10.4244/EIJ-E-25-00019","DOIUrl":"10.4244/EIJ-E-25-00019","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e723-e726"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Restenosis patterns after percutaneous coronary intervention with drug-coated balloons for de novo coronary lesions.","authors":"Kazuki Matsuda, Tetsumin Lee, Takashi Ashikaga, Toshihiro Nozato, Yasutoshi Nagata, Masakazu Kaneko, Ryoichi Miyazaki, Toru Misawa, Masashi Nagase, Tomoki Horie, Mao Terui, Daigo Kachi, Yuki Odanaka, Maki Ohira, Naoya Kikkoji, Ayaka Koido, Megumi Kou, Risako Baba, Akira Takakuma, Taishi Yonetsu, Tetsuo Sasano","doi":"10.4244/EIJ-D-24-01113","DOIUrl":"10.4244/EIJ-D-24-01113","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e766-e768"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}