Food Hygiene and Safety Science最新文献_第9页

[Study of Rapid Simultaneous Determination of 6 Fungicides in Lemon Using Three-Layer Extraction]. [三层萃取法快速同时测定柠檬中6种杀菌剂的研究]

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-02-25 DOI: 10.3358/shokueishi.63.47

Takumi Daimon, Kunihiko Takahashi

引用次数: 0

[Recognition and Prevalence of "Designated Ingredient, etc." in Health Foods]. 【保健食品中“指定成分等”的认识与流行】。

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-02-25 DOI: 10.3358/shokueishi.63.20

T. Chiba, N. Tanemura, C. Nishijima, K. Umegaki

{"title":"[Recognition and Prevalence of \"Designated Ingredient, etc.\" in Health Foods].","authors":"T. Chiba, N. Tanemura, C. Nishijima, K. Umegaki","doi":"10.3358/shokueishi.63.20","DOIUrl":"https://doi.org/10.3358/shokueishi.63.20","url":null,"abstract":"From 2012 to 2017, many adverse events, such as irregular vaginal bleeding and menstrual disorders, associated with the use of health foods containing Pueraria mirifica were reported in PIO-NET. Health foods containing P. mirifica claim mastogenic or body shaping effects, and it is for this reason that many women use these products. As a result, the Japanese government investigated and assessed the possibility of the occurrence of adverse effects associated with the use of other ingredients in health foods and labelled P. mirifica, Coleus forskohlii, black cohosh, and greater celandine as \"designated ingredient, etc.\"The present study showed that recognition of \"designated ingredient, etc.\" was 45.9% and that there was a difference between consumers and healthcare professionals. The prevalence of food containing P. mirifica use was 1.2%. Almost half of users experienced adverse events, such as irregular vaginal bleeding and menstrual disorder. Some subjects had a good perception towards \"designated ingredient, etc.,\" such as \"It seems effective\"(32.7%) and \"It seems good for health\"(18.9%). After reading the descriptive text, their positive perceptions decreased.In conclusion, the recognition of \"designated ingredient, etc.\" is insufficient. To avoid adverse events associated with \"food containing designated ingredient, etc.,\" detailed information should be provided.","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"10 1","pages":"20-26"},"PeriodicalIF":0.3,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80440737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[Important Points at Interpretation ofNongenotoxic-Carcinogenicity Induced by Pesticidesin Rodent Bioassays]. [在啮齿动物生物测定中解释农药诱导的非基因毒性致癌性的要点]。

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-02-25 DOI: 10.3358/shokueishi.63.34

Hiroshi Satoh, Satoshi Machino, Tatsuya Fujii, Midori Yoshida, Satoshi Asano, Yoko Yokoyama, Katsuhiro Miyajima

{"title":"[Important Points at Interpretation ofNongenotoxic-Carcinogenicity Induced by Pesticidesin Rodent Bioassays].","authors":"Hiroshi Satoh, Satoshi Machino, Tatsuya Fujii, Midori Yoshida, Satoshi Asano, Yoko Yokoyama, Katsuhiro Miyajima","doi":"10.3358/shokueishi.63.34","DOIUrl":"https://doi.org/10.3358/shokueishi.63.34","url":null,"abstract":"Assessment of carcinogenicity is important for human health at dietary risk assessment of pesticide residues. This article indicated important points on interpretation of carcinogenicity in toxicological evaluation of pesticide residues based on principles of risk analysis in foods by CODEX to be a guide for risk assessors. This guidance was referred from the guidance on carcinogenicity evaluation by international and/or national organizations, and the interpretations of Food Safety Commissions of Japan (FSCJ) published in their risk assessment reports. We focused on carcinogenicity obtained from routine carcinogenicity bioassays in rodents. The guidance includes the purpose and usefulness of the bioassay studies, consideration points to be carcinogenicity and influencing factors to carcinogenicity in the test to judge carcinogenic hazard at hazard identification. Considering on human relevance as carcinogenic hazard also was proposed using practical case examples. Next, a carcinogenic hazard is evaluated on dose-response relationship to judge points of departure on carcinogenicity. At the end of this article, we challenged our recommendation on future assessment of carcinogenicity to progress from hazard to risk.","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"63 1 1","pages":"34-42"},"PeriodicalIF":0.3,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89574280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Study of Rapid HPLC Method for the Determination of Antioxidants in Foods, and Standard Solution Stability during Storage]. 快速高效液相色谱法测定食品中抗氧化剂及标准溶液贮存稳定性的研究

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-02-25 DOI: 10.3358/shokueishi.63.12

Yoko Mikami, Y. Takagi, H. Miyakawa, Y. Yamajima, Narue Sakamaki, C. Kobayashi

{"title":"[Study of Rapid HPLC Method for the Determination of Antioxidants in Foods, and Standard Solution Stability during Storage].","authors":"Yoko Mikami, Y. Takagi, H. Miyakawa, Y. Yamajima, Narue Sakamaki, C. Kobayashi","doi":"10.3358/shokueishi.63.12","DOIUrl":"https://doi.org/10.3358/shokueishi.63.12","url":null,"abstract":"In this study, we simultaneously determined three antioxidants, butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), and tert-butylhydroquinone (TBHQ), using HPLC equipped both with a photodiode array detector and a fluorescence detector in 25 minutes per sample. Due to the combined use of the two detectors, we could achieve improved target selectivity. Further, quantification at the specific wavelengths for each target substance particularly increased BHT detection sensitivity. This approach enabled us to avoid repeated measurements during daily inspections. Furthermore, detections were performed using LC-MS/MS instead of GC-MS to overcome the problem of helium gas shortage.In addition, we investigated antioxidant stability in standard solutions during storage. Although TBHQ was stable in methanol with ascorbic acid at -20℃, ascorbic acid storage has possibility to lead to decrease in BHT and BHA concentrations. We recognized that the mixture of BHT and BHA dissolved in methanol at 4℃ and that of BHT, BHA and TBHQ dissolved in methanol with ascorbic acid at -20℃ were suitable for about one year.","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"19 1","pages":"12-19"},"PeriodicalIF":0.3,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86534839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

[Consultation and Information Source of Interaction between Drugs and Health Foods among Pharmacists and Dietitians]. [药师、营养师对药品与保健食品相互作用的咨询及信息来源]。

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-02-25 DOI: 10.3358/shokueishi.63.27

T. Chiba, N. Tanemura, C. Nishijima

{"title":"[Consultation and Information Source of Interaction between Drugs and Health Foods among Pharmacists and Dietitians].","authors":"T. Chiba, N. Tanemura, C. Nishijima","doi":"10.3358/shokueishi.63.27","DOIUrl":"https://doi.org/10.3358/shokueishi.63.27","url":null,"abstract":"The prevalence of health food use is increasing not only among healthy individuals but also among patients. Many patients consume drugs and health foods concomitantly, and most of them use more than one drug and one health food. In this regard, the interactions between drugs and health foods should be addressed. However, it is not clear where healthcare professionals can get sufficient information about the interactions between drugs and health foods. To address this issue, we conducted an online questionnaire about the consultation and attitude concerning and information source of interactions between drugs and health foods among pharmacists and dietitians. Only 29.7% of pharmacists and 14.0% of dietitians always confirmed the use of health foods among their patients, even though they work at pharmacies or hospitals. Regarding concomitant use, 79.2% of pharmacists and 60.2% of dietitians allowed their patients to continue concomitant use, and less than 20% of them advised their patients to avoid concomitant use. Most of them checked the manufacturer's website and could not obtain sufficient information about the interactions between drugs and health foods. However, they utilized the \"Information system on safety and effectiveness for health foods (HFNet),\" which is the website of the National Institutes of Biomedical Innovation, Health and Nutrition, to obtain information, if they were aware of this. In conclusion, pharmacists and dietitians need more information about the interactions between drugs and health foods, and HFNet may play an important role as information source.","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"12 1","pages":"27-33"},"PeriodicalIF":0.3,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72490755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

[Validation Study on an Improved Quantitative Method for Aflatoxins in Foods]. 食品中黄曲霉毒素定量检测改进方法的验证研究

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-02-25 DOI: 10.3358/shokueishi.63.43

Masato Yoshimitsu, Kotaro Uchida, Masakazu Osakada, Hiroshi Matsui, Ryosei Ueno, Takuya Fujiwara, K. Akutsu, M. Shinya

{"title":"[Validation Study on an Improved Quantitative Method for Aflatoxins in Foods].","authors":"Masato Yoshimitsu, Kotaro Uchida, Masakazu Osakada, Hiroshi Matsui, Ryosei Ueno, Takuya Fujiwara, K. Akutsu, M. Shinya","doi":"10.3358/shokueishi.63.43","DOIUrl":"https://doi.org/10.3358/shokueishi.63.43","url":null,"abstract":"As an analytical method for aflatoxins in foods, the analytical method based on the notification by the director of the Food Safety Department, Pharmaceutical and Food Safety Bureau, Ministry of Health, Labour and Welfare (August 16, 2011) has been established. In order to improve the operability and analytical performance of the conventional method, this study aimed to construct an improved method that optimized selection of immunoaffinity column (IAC) and purifying condition, and omitted evaporation after the purification with IAC. In the recovery test performed by adding 2.5 ng/g of aflatoxin B1, B2, G1 and G2 standard solutions into 9 kinds of food samples, the improved method achieved the established target values: 77.0-99.7% of recovery, 1.7-5.6% of intra-assay coefficient of validation, and 0.9-3.6% of inter-assay of coefficient of variation, respectively. The improved method also achieved 4.3-10.5% greater recovery and 1.5 hours shorter preparation time than the conventional one. These results indicate applicability of the improved method for 9 kinds of foods and its efficacy as an analytical method for aflatoxins in foods.","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"120 1","pages":"43-46"},"PeriodicalIF":0.3,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87748449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Electrophysiological Effect of Citreoviridin on Human InducedPluripotent Stem Cell-derived Cardiomyocytes]. [黄绿霉素对人多能干细胞源性心肌细胞的电生理影响]。

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-01-01 DOI: 10.3358/shokueishi.63.210

Yosuke Uchiyama, Daiju Yamazaki, Naoki Kobayashi, Yasunari Kanda, Yoshiko Sugita-Konishi

{"title":"[Electrophysiological Effect of Citreoviridin on Human InducedPluripotent Stem Cell-derived Cardiomyocytes].","authors":"Yosuke Uchiyama, Daiju Yamazaki, Naoki Kobayashi, Yasunari Kanda, Yoshiko Sugita-Konishi","doi":"10.3358/shokueishi.63.210","DOIUrl":"https://doi.org/10.3358/shokueishi.63.210","url":null,"abstract":"Citreoviridin (CTV) is a mycotoxin produced by various fungi, including Penicillium citreonigrum. One of the toxicities reportedly associated with CTV is neurotoxicity. CTV is also suspected to be associated with acute cardiac beriberi (also known as \"Shoshin-kakke\") and Keshan disease, which can have adverse effects on the heart, so the in vivo and in vitro toxicity of CTV on the heart or cardiomyocytes in experimental animal models have been reported. However, the toxicity of CTV for the human heart, especially its electrophysiological effect, remains poorly understood. Therefore, to investigate the electrophysiological effect of CTV on the human cardiomyocytes, we conducted a multi-electrode array (MEA) using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The MEA revealed that 30 μmol/L of CTV stopped the beating of hiPSC-CMs, and the field potential duration and first peak amplitude were shortened at 10 μmol/L. Before the hiPSC-CMs stopped beating, the length of the inter-spike interval varied two- to four-fold. These results demonstrated that CTV induced an electrophysiological disturbance on human cardiomyocytes. This is first paper to elucidate the electrophysiological effect of CTV on human heart directly and may aid in analyzing the risk associated with CTV to ensure food safety.","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"63 6","pages":"210-217"},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9419923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Analysis of Ciguatoxins in the Spotted Knifejaw, Oplegnathus punctatus from the Waters of Japan]. [日本水域斑点刀颚鱼(Oplegnathus punctatus)的雪卡毒素分析]。

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-01-01 DOI: 10.3358/shokueishi.63.190

Takumi Tomikawa, Kyoko Kuniyoshi, Shiori Ito, Satsuki Sakugawa, Akira Ishikawa, Toshio Saito, Takashi Kojima, Hiroshi Asakura, Tsuyoshi Ikehara, Naomasa Oshiro

{"title":"[Analysis of Ciguatoxins in the Spotted Knifejaw, Oplegnathus punctatus from the Waters of Japan].","authors":"Takumi Tomikawa, Kyoko Kuniyoshi, Shiori Ito, Satsuki Sakugawa, Akira Ishikawa, Toshio Saito, Takashi Kojima, Hiroshi Asakura, Tsuyoshi Ikehara, Naomasa Oshiro","doi":"10.3358/shokueishi.63.190","DOIUrl":"https://doi.org/10.3358/shokueishi.63.190","url":null,"abstract":"Ciguatera fish poisoning (CFP) is recognized as the most frequent seafood poisoning due to the consumption of fish containing the principal toxins, ciguatoxins (CTXs). In Japan, CFP events have been reported annually from Okinawa and Amami Islands, locating subtropical regions. In addition, there have been reported several outbreaks due to consumption of the fish caught from the Pacific coast of the Mainland and they were often caused by the matured spotted knifejaw, Oplegnathus punctatus. As part of our research on CFP in Japan, we investigated CTXs analysis by LC-MS/MS on 176 individuals of O. punctatus (weight: 100-6,350 g, standard length: 13-60 cm) from the coast of the Mainland (Honshu, Shikoku, and Kyushu), Amami, Okinawa, and Ogasawara (Bonin) Islands. CTXs were detected from only two specimens collected from Okinawa. Total CTXs levels of the two specimens were at 0.014 and 0.040 μg/kg, respectively, exceeding FDA guidance level at 0.01 μg CTX1B equivalent/kg. However, they might be little risk of CFP because consuming over 1.5 kg of flesh is needed to develop intoxication. The toxins consisted of CTX1B analogs including CTX1B, 52-epi-54-deoxyCTX1B, CTX4A, and CTX4B, and no CTX3C analogs, supporting the finding that ciguatoxic fishes in Okinawan Waters containing only CTX1B analogs.","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"63 5","pages":"190-194"},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40663540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

[Determination of Chlorothalonil Metabolite I in Livestock Products by LC-MS/MS]. 畜产品中百菌清代谢物I的LC-MS/MS测定

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-01-01 DOI: 10.3358/shokueishi.63.195

Maki Kobayashi, Naoko Sakai, Yuki Ohmachi, Yuka Morita, Satoru Nemoto, Kenji Ohtsuka

引用次数: 0

[AFM₁ Content Survey in Dairy Products for Infants]. [AFM1婴幼儿乳制品含量调查]。

IF 0.3 4区农林科学

Food Hygiene and Safety Science Pub Date : 2022-01-01 DOI: 10.3358/shokueishi.63.158

Sayaka Teratani, Masami Ki, Taro Murakami, Satoshi Takatori

{"title":"[AFM1 Content Survey in Dairy Products for Infants].","authors":"Sayaka Teratani, Masami Ki, Taro Murakami, Satoshi Takatori","doi":"10.3358/shokueishi.63.158","DOIUrl":"https://doi.org/10.3358/shokueishi.63.158","url":null,"abstract":"Infant formula in liquid for childcare can be stored at room temperature for a certain period of time, reducing the burden of childcare and preparing for disasters. Against this background, domestic manufacturing and sales began in March 2019. AFM1 is a metabolite of aflatoxin B1 (AFB1), a carcinogenic mycotoxin, and is contained in the milk of livestock fed a diet contaminated with AFB1. At present, standard values have not been set for infant formula in liquid as well as prepared infant formula in liquid, and infants consume a large amount of dairy products per body weight, so care must be taken in the intake.In this study, we investigated the actual condition of AFM1 content in dairy products with high intake of infants. As a result of the investigation, the AFM1 of the detected dairy products was 0.001 to 0.005 μg/kg, which was extremely small compared to the AFM1 in the dairy products reported so far. Since infant nutrition depends on dairy products, it is undeniable that they may consume more than adults, so continuous research is needed.","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"63 4","pages":"158-162"},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40335168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0