Pulmonology最新文献

{"title":"Atypical surge of hospitalized and severe cases of pertussis: A single center 19-years study from China.","authors":"Y Hu, L Wang, K Yao, Q Wang","doi":"10.1016/j.pulmoe.2024.06.006","DOIUrl":"https://doi.org/10.1016/j.pulmoe.2024.06.006","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application and internal validation of lung ultrasound score in COVID-19 setting: Correspondence.","authors":"H Daungsupawong, V Wiwanitkit","doi":"10.1016/j.pulmoe.2024.06.001","DOIUrl":"https://doi.org/10.1016/j.pulmoe.2024.06.001","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of pneumocystosis under anti-PD-L1 therapy.","authors":"Maria João Santos, Maria João Cavaco, Fernanda Paula Santos, Filipe Froes","doi":"10.1016/j.pulmoe.2024.05.004","DOIUrl":"https://doi.org/10.1016/j.pulmoe.2024.05.004","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application and internal validation of lung ultrasound score in COVID-19 setting: The ECOVITA observational study. Authors' reply.","authors":"L Rinaldi, F Perrotta","doi":"10.1016/j.pulmoe.2024.06.004","DOIUrl":"https://doi.org/10.1016/j.pulmoe.2024.06.004","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methicilin-susceptible Staphylococcus aureus clonal complex 398: An unusual agent of necrotizing pneumonia","authors":"C. Nobre , P. Moniz , N.A. Faria","doi":"10.1016/j.pulmoe.2023.10.003","DOIUrl":"10.1016/j.pulmoe.2023.10.003","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2531043723001964/pdfft?md5=ac54245c2ac3ed3e8ad299b51a7b5e84&pid=1-s2.0-S2531043723001964-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138435391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of automatic 6-minute walking test recording system in patients with chronic respiratory diseases","authors":"R. Torres-Castro , H. Pascual , A. Alonso , E. Gimeno-Santos , M. Palomo , J.A. Barberà , J. Bigorra , J. Batlle , X. Masip-Bruin , I. Blanco","doi":"10.1016/j.pulmoe.2023.08.011","DOIUrl":"10.1016/j.pulmoe.2023.08.011","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2531043723001666/pdfft?md5=1b8ace6f12e41e16584a2e2750835bc5&pid=1-s2.0-S2531043723001666-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41159327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of immune-related adverse events and outcomes in patients with NSCLC treated with immune-checkpoint inhibitors","authors":"M. Serino ,&nbsp;C. Freitas ,&nbsp;M. Martins ,&nbsp;P. Ferreira ,&nbsp;C. Cardoso ,&nbsp;F. Veiga ,&nbsp;V. Santos ,&nbsp;D. Araújo ,&nbsp;H. Novais-Bastos ,&nbsp;A. Magalhães ,&nbsp;H. Queiroga ,&nbsp;G. Fernandes ,&nbsp;V. Hespanhol","doi":"10.1016/j.pulmoe.2022.03.003","DOIUrl":"10.1016/j.pulmoe.2022.03.003","url":null,"abstract":"<div><h3>Objective</h3><p>To identify predictors of immune-related adverse events (IRAEs) in patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs). Assess associations between outcomes and the development of IRAEs.</p></div><div><h3>Methods</h3><p>Retrospective analysis of patients with NSCLC treated with ICIs between 2016 and 2020 in the Pulmonology Department of our hospital. Patients with and without IRAEs were compared. A logistic regression analysis was performed to determine predictors of IRAEs. Progression-free survival (PFS) and overall survival (OS) curves were calculated using the Kaplan-Meier method, and the long-rank test was used to assess survival differences between groups. Univariate and multivariate Cox proportional-hazards regression models were used to identify factors associated with PFS and OS. The value considered statistically significant was p≤0.05.</p></div><div><h3>Results</h3><p>A total of 184 patients (77.7% men, mean age 66.9±9.5 years) treated with ICIs were analyzed. During follow-up, 49 (26.6%) patients developed IRAEs and 149 (81.0%) died. According to the multivariate logistic regression analysis, treatment with statins (OR:3.15; <em>p</em> = 0.007), previous systemic corticosteroid therapy (OR:3.99; <em>p</em> = 0.001), disease controlled as response to ICI (OR:5.93; <em>p</em> &lt; 0.001) and higher hemoglobin values (OR:1.28; <em>p</em> = 0.040) were independent predictors for the development of IRAEs. Patients who developed IRAEs had significantly longer medians of PFS (41.0 vs 9.0 weeks, <em>p</em> &lt; 0.001) and OS (89.0 vs 28.0 weeks; <em>p</em> &lt; 0.001).</p></div><div><h3>Conclusions</h3><p>Patients treated with statins, pre-ICI systemic corticosteroids, higher baseline hemoglobin value and controlled disease as initial response to ICI had a higher risk of developing IRAEs. The development of IRAEs was associated with better outcomes.</p></div>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2531043722000769/pdfft?md5=f68e9ab9cfdaae86cb0d8b61009aa97b&pid=1-s2.0-S2531043722000769-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76640049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nontuberculous Mycobacteria in Portugal: Trends from the last decade","authors":"A. Santos ,&nbsp;S. Carneiro ,&nbsp;A. Silva ,&nbsp;J.P. Gomes ,&nbsp;R. Macedo","doi":"10.1016/j.pulmoe.2022.01.011","DOIUrl":"10.1016/j.pulmoe.2022.01.011","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Nontuberculous mycobacteria (NTM) are opportunistic human pathogens found in the environment. The transmission seems to be associated with inhalation of aerosol droplets, ingestion or trauma events. Recent studies indicate that NTM disease is increasing worldwide, however, the true clinical impact of NTM infections is difficult to determine due to challenges in discriminating between disease and colonization as they are ubiquitous in the environment. In addition, understanding the epidemiology of NTM is difficult and has not yet been established. In this work, we used a country NTM representative collection from the National Reference Laboratory for Tuberculosis (NRL-TB) of the National Institute of Health (INSA), to characterize the circulation trends of NTM species in Portugal and the most affected regions, contributing to a better understanding of the NTM epidemiology.</p></div><div><h3>Material and methods</h3><p>We conducted a nationwide retrospective study where all individuals with positive NTM cultures at the NRL-TB of the INSA from 2014 to December 2020 were included. Positive cultures were identified using GenoType Mycobacterium CM/AS® (Hain Lifescience) according to manufacturer's instructions, or hsp65 DNA sequencing as previously described. Social-demographic data from patients were also analyzed and patients classified into 3 groups according only to microbiological data, “definite NTM disease”, “NTM colonization” and, “possible NTM disease”.</p></div><div><h3>Results</h3><p>In the period 2014-2020, the NRL-TB performed 50397 cultures. Among these, 1118 cultures were NTM positive retrieved from 944. Most of our cases were in patients whose mean age was 64±15.9 years, and no significant differences between gender was observed, although more frequent in male patients. Overall, from the 944 cases, we were able to identified 93 “definite NTM disease” cases and 79 “possible NTM disease”. Mycobacterium avium complex (MAC) (40,8%), Mycobacterium abscessus-chelonae complex (MABC) (9,6%) and Mycobacterium fortuitum (6,3%) were responsible for most of the infections. The geographical distribution of NTM cases varied significantly and was possible to observe that was independent of population density. The region were most cases occurred was Lisbon Metropolitan Area (31,9%), followed by North (25,3%) and Centre (24,4%), however North region has the highest number of “definite NTM disease” cases (n=33).</p></div><div><h3>Conclusions</h3><p>This is the first national wide epidemiological study on this subject, contributing to a better understanding of NTM dynamics in Portugal. MAC was the NTM species responsible for the majority of infections and, LMA the region with the highest number of cases. It was also possible to conclude that the number of NTM isolates is independent of the demography of the region.</p></div>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S253104372200023X/pdfft?md5=9db3e296903f176f3c592a4a113499d6&pid=1-s2.0-S253104372200023X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83335370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between sputum myeloperoxidase concentration and acute exacerbation of bronchiectasis","authors":"B. Yang ,&nbsp;H. Lee ,&nbsp;H. Yun ,&nbsp;C. Seong ,&nbsp;E.-G. Kim ,&nbsp;J.‑K. Choi","doi":"10.1016/j.pulmoe.2023.10.006","DOIUrl":"10.1016/j.pulmoe.2023.10.006","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2531043723001976/pdfft?md5=32e497ab4fdd7d16e63a1765309bb6f6&pid=1-s2.0-S2531043723001976-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138500160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regarding the prognostic factors in patients with ALK-positive non-small cell lung cancer treated with crizotinib","authors":"Limei Hu ,&nbsp;Youjun Xie ,&nbsp;Hongying Zhao","doi":"10.1016/j.pulmoe.2024.02.007","DOIUrl":"10.1016/j.pulmoe.2024.02.007","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":null,"pages":null},"PeriodicalIF":10.4,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2531043724000199/pdfft?md5=8ee48f5a07ad4c0dd58d049fc6635268&pid=1-s2.0-S2531043724000199-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139944691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}