PulmonologyPub Date : 2024-11-01DOI: 10.1016/j.pulmoe.2024.03.002
{"title":"Complete response to mTOR inhibitor following JAKi failure in severe pulmonary sarcoidosis","authors":"","doi":"10.1016/j.pulmoe.2024.03.002","DOIUrl":"10.1016/j.pulmoe.2024.03.002","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"30 6","pages":"Pages 639-641"},"PeriodicalIF":10.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140770606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PulmonologyPub Date : 2024-11-01DOI: 10.1016/j.pulmoe.2022.02.009
{"title":"Pre- and post-COVID practice of interventional pulmonology in adults in Portugal","authors":"","doi":"10.1016/j.pulmoe.2022.02.009","DOIUrl":"10.1016/j.pulmoe.2022.02.009","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>There is a lack of information regarding bronchoscopy practice in adults in Portugal. Our objective was to obtain an overview of the characteristics, resources, techniques and behaviors in national interventional pulmonology (IP) units, before and after SARS-CoV-2 outbreak.</div></div><div><h3>Materials and Methods</h3><div>An online survey was developed by an expert panel with a total of 46 questions comprising the specifications of each unit, namely physical space, equipment, staff, procedure planning, monitoring, technical differentiation, and numbers pre- and post-COVID-19. Forty-one interventional pulmonology centers were invited to participate between April and May 2021.</div></div><div><h3>Results</h3><div>37 units (90.2%) responded to the survey. The majority (64.9%) have a fully dedicated space with a weekly presence of ≥3 chest physicians (82.1%) and support of an anesthesiologist on specific days (48.6%). There is marked heterogeneity in the IP unit's equipment, and 56.8% acquired disposable bronchoscopes after COVID-19 pandemics. Pre-bronchoscopy hemogram, platelet count and coagulation tests are regularly asked by more than 90% of the units, even when deep sedation or biopsies are not planned. In 97.3% of cases, topical anesthesia and midazolam are utilized. Propofol (21.6%) and fentanyl (29.7%) are occasionally employed in some institutions. Most units use ancillary sampling techniques to diagnose central or peripheral lesions, with radial EBUS being used for guidance of distal procedures in 37.8% of centers, linear EBUS and EUS-B-FNA for mediastinal diagnosis and/or staging in 45.9% and 27.0% of units, respectively. Cryobiopsies are used by 21.6% of respondents to diagnose diffuse lung diseases. Rigid bronchoscopy is performed in 37.8% of centers. There was a decrease in the number of flexible (<em>p</em> < 0.001) and rigid (<em>p</em> = 0.005) bronchoscopies and an upscale of personal protective equipment (PPE) during the COVID-19 outbreak.</div></div><div><h3>Conclusions</h3><div>IP units have variable bronchoscopic practices, but during the COVID-19 pandemic, they complied with most international recommendations, as elective procedures were postponed and PPE levels increased.</div></div>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"30 6","pages":"Pages 537-545"},"PeriodicalIF":10.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85428382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PulmonologyPub Date : 2024-11-01DOI: 10.1016/j.pulmoe.2024.05.002
{"title":"Perceptions of the Portuguese population on vaccination – The specific view of Chronic Respiratory Disease patients","authors":"","doi":"10.1016/j.pulmoe.2024.05.002","DOIUrl":"10.1016/j.pulmoe.2024.05.002","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"30 6","pages":"Pages 663-667"},"PeriodicalIF":10.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141441149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PulmonologyPub Date : 2024-11-01DOI: 10.1016/j.pulmoe.2024.05.004
Maria João Santos , Maria João Cavaco , Fernanda Paula Santos , Filipe Froes
{"title":"A rare case of pneumocystosis under anti-PD-L1 therapy","authors":"Maria João Santos , Maria João Cavaco , Fernanda Paula Santos , Filipe Froes","doi":"10.1016/j.pulmoe.2024.05.004","DOIUrl":"10.1016/j.pulmoe.2024.05.004","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"30 6","pages":"Pages 671-672"},"PeriodicalIF":10.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PulmonologyPub Date : 2024-09-13DOI: 10.1016/j.pulmoe.2024.05.005
M Chilosi, S Piciucchi, C Ravaglia, P Spagnolo, N Sverzellati, S Tomassetti, W Wuyts, V Poletti
{"title":"\"Alveolar stem cell exhaustion, fibrosis and bronchiolar proliferation\" related entities. A narrative review.","authors":"M Chilosi, S Piciucchi, C Ravaglia, P Spagnolo, N Sverzellati, S Tomassetti, W Wuyts, V Poletti","doi":"10.1016/j.pulmoe.2024.05.005","DOIUrl":"https://doi.org/10.1016/j.pulmoe.2024.05.005","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":" ","pages":""},"PeriodicalIF":10.4,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PulmonologyPub Date : 2024-09-01DOI: 10.1016/j.pulmoe.2022.12.003
{"title":"Prediction of exercise respiratory limitation from pulmonary function tests","authors":"","doi":"10.1016/j.pulmoe.2022.12.003","DOIUrl":"10.1016/j.pulmoe.2022.12.003","url":null,"abstract":"<div><h3>Background</h3><p>Evaluation of unexplained exercise intolerance is best resolved by cardiopulmonary exercise testing (CPET) which enables the determination of the exercise limiting system in most cases. Traditionally, pulmonary function tests (PFTs) at rest are not used for the prediction of a respiratory limitation on CPET.</p></div><div><h3>Objective</h3><p>We sought cut-off values on PFTs that might, <em>a priori</em>, rule-in or rule-out a respiratory limitation in CPET.</p></div><div><h3>Methods</h3><p>Patients who underwent CPET in our institute were divided into two groups according to spirometry: obstructive and non-obstructive. Each group was randomly divided 2:1 into derivation and validation cohorts respectively. We analyzed selected PFTs parameters in the derivation groups in order to establish maximal and minimal cut-off values for which a respiratory limitation could be ruled-in or ruled-out. We then validated these values in the validation cohorts.</p></div><div><h3>Results</h3><p>Of 593 patients who underwent a CPET, 126 were in the obstructive and 467 in the non-obstructive group. In patients with obstructive lung disease, forced expiratory volume in 1 second (FEV<sub>1</sub>) ≥ 61% predicted could rule out a respiratory limitation, while FEV<sub>1</sub> ≤ 33% predicted was always associated with a respiratory limitation. For patients with non-obstructive spirometry, FEV<sub>1</sub> of ≥ 73% predicted could rule-out a respiratory limitation. Application of this algorithm might have saved up to 47% and 71% of CPETs in our obstructive and non-obstructive groups, respectively.</p></div><div><h3>Conclusion</h3><p>Presence or absence of a respiratory limitation on CPET can be predicted in some cases based on a PFTs performed at rest.</p></div>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"30 5","pages":"Pages 452-458"},"PeriodicalIF":10.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2531043723000016/pdfft?md5=1ff4d9adf371592749df33b9cd7b6948&pid=1-s2.0-S2531043723000016-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10577847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PulmonologyPub Date : 2024-09-01DOI: 10.1016/j.pulmoe.2024.03.001
{"title":"Efficacy of elexacaftor-tezacaftor-ivacaftor in portuguese adolescents and adults with cystic fibrosis carrying non-F508del variants","authors":"","doi":"10.1016/j.pulmoe.2024.03.001","DOIUrl":"10.1016/j.pulmoe.2024.03.001","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"30 5","pages":"Pages 485-487"},"PeriodicalIF":10.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2531043724000412/pdfft?md5=8628f15c6780a6929b1b1b684d893bea&pid=1-s2.0-S2531043724000412-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140771833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PulmonologyPub Date : 2024-09-01DOI: 10.1016/j.pulmoe.2024.02.009
{"title":"Post-pandemic respiratory infection trends among Northern Chinese children: Challenges and responses","authors":"","doi":"10.1016/j.pulmoe.2024.02.009","DOIUrl":"10.1016/j.pulmoe.2024.02.009","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"30 5","pages":"Pages 419-421"},"PeriodicalIF":10.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2531043724000229/pdfft?md5=e337bc9f47100473592fdd26ad67243d&pid=1-s2.0-S2531043724000229-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}