Pulmonology最新文献

{"title":"Comment on 'Prevalence, risk factors, and clinical implications of failed spirometry in adults: Results from NHANES 2007-2012'.","authors":"Etika Rana, Subhasish Chatterjee, Mousumi Saha","doi":"10.1080/25310429.2026.2619322","DOIUrl":"https://doi.org/10.1080/25310429.2026.2619322","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2619322"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor - dual-correction robotic bronchoscopy system with ultra-thin catheter for diagnosing challenging peripheral pulmonary nodules.","authors":"Suman Pradhan, Subhasish Chatterjee, Mousumi Saha","doi":"10.1080/25310429.2026.2630540","DOIUrl":"https://doi.org/10.1080/25310429.2026.2630540","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2630540"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146229729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-dose theophylline in mild to moderate Chronic Obstructive Pulmonary Disease: A randomized clinical trial in China.","authors":"Yumin Zhou, Cuiqiong Dai, Fan Wu, Jianwu Xu, Zhishan Deng, Li Lin, Jie Cao, Hong Huang, Yiran Wang, Jia Tian, Peiyu Huang, Heshen Tian, Jieqi Peng, Shan Xiao, Xiang Wen, Huajing Yang, Youlan Zheng, Zihui Wang, Ningning Zhao, Lifei Lu, Haiyan Zhao, Lingwei Wang, Qijian Cheng, Shan Cai, Zhiyi He, Yinghua Ying, Qiuyue Wang, Pixin Ran","doi":"10.1080/25310429.2026.2652159","DOIUrl":"https://doi.org/10.1080/25310429.2026.2652159","url":null,"abstract":"<p><strong>Background: </strong>Low-dose theophylline has anti-inflammatory effects, but its efficacy in mild to moderate COPD remains controversial.</p><p><strong>Research question: </strong>Is low dose theophylline effective and safe in patients with mild to moderate COPD?</p><p><strong>Methods: </strong>In this prospective, parallel-group, randomised, double-blind, placebo-controlled trial across ten centres in China, subjects with mild to moderate COPD were randomized 2:1 to oral low-dose theophylline sustained-release tablets (100 mg twice daily) or matching placebo for 12 months. Primary endpoints were between-group differences in pre-bronchodilator FEV₁ change from baseline to 12 months and annual exacerbation rate.</p><p><strong>Findings: </strong>734 subjects were randomized; 615 completed the study. Compared with placebo, low-dose theophylline significantly ameliorated FEV₁ before bronchodilator use by 30 ml [95% CI, 3 to 57 ml] (<i>p</i> = 0.031) at month 12, with a between-group difference in mean change from baseline of 28 ml/year [95% CI, -2 to 58 ml/year] (<i>p</i> = 0.063). The annual exacerbation rate did not differ between groups (0.46 ± 0.03 vs 0.43 ± 0.04 per patient-year; RR, 1.07 [95% CI, 0.84 to 1.36]; <i>p</i> = 0.607). In addition, the incidence of adverse events was comparable between both groups.</p><p><strong>Interpretation: </strong>In mild to moderate COPD, low-dose theophylline was well-tolerated but did not reduce exacerbation rates. A modest improvement in pre-bronchodilator FEV₁ was observed, though its magnitude was limited. Larger trials are needed to further evaluate its potential to improve lung function in this population.</p>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2652159"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Pulmonary blood volume redistribution in COVID-19 patients of different severity and its predictive value for six-month outcomes in the less pathogenic Omicron variant.","authors":"Zhao Xuemei","doi":"10.1080/25310429.2026.2650732","DOIUrl":"https://doi.org/10.1080/25310429.2026.2650732","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2650732"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147516608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correspondence 'Trajectories of lung recovery following COVID-19 in a prospective multicentric cohort study: Impact of sleep apnea and its treatment by continuous positive airway pressure'.","authors":"Aarunee Srivastava, Sandeep Pattnaik","doi":"10.1080/25310429.2026.2664927","DOIUrl":"https://doi.org/10.1080/25310429.2026.2664927","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2664927"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to editor: Low-dose theophylline in mild to moderate chronic obstructive pulmonary disease: A randomized clinical trial in China.","authors":"Ankita Jalota, Anchal Thakur, Sunita Sharma","doi":"10.1080/25310429.2026.2663670","DOIUrl":"https://doi.org/10.1080/25310429.2026.2663670","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2663670"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: Methodological considerations on the longitudinal changes of obstructive sleep apnea and cardiovascular outcomes.","authors":"Di Lian","doi":"10.1080/25310429.2026.2664334","DOIUrl":"https://doi.org/10.1080/25310429.2026.2664334","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2664334"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of an early follow-up visit on adherence and adherence trajectories after initiation of continuous positive airway pressure therapy for obstructive sleep apnea.","authors":"Jérémy Duval, Joëlle Texereau, Sébastien Bailly, Jean Louis Pépin","doi":"10.1080/25310429.2026.2641311","DOIUrl":"https://doi.org/10.1080/25310429.2026.2641311","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Continuous positive airway pressure (CPAP) outcomes depends on adherence, yet the effect of different patient support strategies on adherence is poorly studied. This study assessed whether an early home visit improves CPAP adherence and trajectories in obstructive sleep apnoea, and which patients benefit most.</p><p><strong>Material and methods: </strong>This multicenter cohort study analysed home service provider data from adults starting CPAP in 2019-2022 who had >90 days of telemonitoring data. Adherence was compared before and after the early visit, overall and in subgroups based on adherence over the 15 days after starting CPAP (<2 [low], 2-<4 [intermediate] or ≥4 [high] h/night). Adherence trajectories were also determined.</p><p><strong>Results: </strong>A total of 4,924 patients were included (62.3% male, mean age 59 ± 13 years, apnoea-hypopnoea index 40 ± 17/h). The early follow-up visit took place 16 ± 5 days after CPAP initiation. Change in adherence in the week after versus week before the early visit was 14 ± 3 min/night overall, and -7 ± 2, 60 ± 4, 102 ± 5 min/night in the high, intermediate, and low adherence subgroups, respectively (<i>p</i> < 0.01). Adherence gradually decreased after therapy initiation, increased in the 1-2 days before the visit, then declined. Cluster analysis identified two profiles across all early adherence subgroups: responders and non-responders (those with or without better CPAP usage after the early visit, respectively). Responders were slightly older and had higher CPAP motivation than non-responders; higher leak and higher residual AHI predicted improved adherence after the early visit in the intermediate and low adherence subgroups, respectively.</p><p><strong>Conclusions: </strong>An early home visit intervention significantly improved short-term adherence for low and intermediate CPAP adherers. Cluster analysis revealed two distinct adherence trajectories supporting the need for personalised follow-up.</p>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2641311"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correspondence: 'Interpreting urinary incontinence outcomes following pulmonary rehabilitation requires further methodological scrutiny'.","authors":"Nikita Vaid, Kanika Bhatia, Rittu Sharma","doi":"10.1080/25310429.2026.2623659","DOIUrl":"https://doi.org/10.1080/25310429.2026.2623659","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2623659"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Prevalence, type, and clinical implications of CFTR variants in bronchiectasis\".","authors":"Shanvi Priya, Mousumi Saha, Shivi Bajpai","doi":"10.1080/25310429.2026.2629621","DOIUrl":"https://doi.org/10.1080/25310429.2026.2629621","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"32 1","pages":"2629621"},"PeriodicalIF":6.4,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}