Clinical Psychological Science最新文献

Environmental Exposures and Computational Mechanisms in Psychosis Risk: Insights from a Multi-Site Cohort. 环境暴露和精神病风险的计算机制：来自多地点队列的见解。

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-10-12 DOI: 10.1177/21677026261488357

Luz Maria Alliende, Victor Pokorny, Benson Ku, Natalie Larson, Gregory P Strauss, L Lauren Ellman, Elaine F Walker, Philip Corlett, Jason Schiffman, Scott W Woods, A Powers, S Silverstein, James Waltz, Richard Zinbarg, Shuo Chen, Trevor F Williams, Joshua Kenney, James M Gold, Vijay A Mittal

{"title":"Environmental Exposures and Computational Mechanisms in Psychosis Risk: Insights from a Multi-Site Cohort.","authors":"Luz Maria Alliende, Victor Pokorny, Benson Ku, Natalie Larson, Gregory P Strauss, L Lauren Ellman, Elaine F Walker, Philip Corlett, Jason Schiffman, Scott W Woods, A Powers, S Silverstein, James Waltz, Richard Zinbarg, Shuo Chen, Trevor F Williams, Joshua Kenney, James M Gold, Vijay A Mittal","doi":"10.1177/21677026261488357","DOIUrl":"10.1177/21677026261488357","url":null,"abstract":"This study leverages computational psychiatry to examine weighting of perceptual priors and reinforcement learning (RL) as potential pathways connecting environmental stressors to psychosis risk. 506 participants with psychosis-like experiences (PLE) and 328 controls performed behavioral tasks measuring these mechanisms, in addition to symptom assessments. Participants' childhood area social fragmentation and childhood opportunities were also extracted. The association between environmental, computational and clinical measures was assessed, as were mediation pathways. Higher social fragmentation was associated with deficits in RL (r(410)=0.19, p<.001) and lower opportunities were associated with overweighting perceptual priors (r(290)= -0.16, p=.02) as well as issues in RL (r(307)=-0.14, p=.02) for PLE participants. Less available childhood opportunities were also related to more severe positive symptoms (r(354)=-0.14, p=.03). We found a potential pathway connecting available childhood opportunities to positive symptomatology through the mediating effect of overweighting perceptual priors (ACME=-4.91, p=.04). Environmental characteristics could shape symptom severity through computational mechanisms.","PeriodicalId":54234,"journal":{"name":"Clinical Psychological Science","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13664154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149197980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Re-Envisioning Clinical Science Training: Open Science as One of Many Important Steps. 重新设想临床科学培训：开放科学是许多重要步骤之一。

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-09-29 DOI: 10.1177/21677026261421153

David I K Moniz-Lewis, Victoria R Votaw, Cassandra L Boness, Katie Witkiewitz

引用次数: 0

Building Open Science into Graduate Training in Clinical Psychology. 开放科学在临床心理学研究生培养中的应用

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-09-28 DOI: 10.1177/21677026251409757

Jeffrey M Girard

引用次数: 0

Improving science will require more than just training. 提高科学水平需要的不仅仅是培训。

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-09-28 DOI: 10.1177/21677026251408051

Kevin M King, P Priscilla Lui, Jonas Dora

引用次数: 0

Leveraging machine learning to personalize depression treatment: A pre-registered study of 828 adults randomized to a digital single-session intervention or waitlist. 利用机器学习个性化抑郁症治疗：一项对828名成年人的预注册研究，随机分配到数字单次干预或等待名单中。

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-09-22 DOI: 10.1177/21677026261473154

E J Jardas, Jacqueline Howard, Lorenzo Lorenzo-Luaces

{"title":"Leveraging machine learning to personalize depression treatment: A pre-registered study of 828 adults randomized to a digital single-session intervention or waitlist.","authors":"E J Jardas, Jacqueline Howard, Lorenzo Lorenzo-Luaces","doi":"10.1177/21677026261473154","DOIUrl":"10.1177/21677026261473154","url":null,"abstract":"Some digital single-session interventions (SSI) for depression appear effective, at least in youth, but not everyone benefits. The present study uses machine learning methods to develop a treatment matching algorithm for a digital SSI, the Common Elements Toolbox (COMET), versus a waitlist control. 828 adults with a current or past mental health problem were randomized to COMET or a waitlist control. Elastic net regularization models with 10-fold cross-validation were used to develop a Personalized Advantage Index (PAI) indicating the relative benefit of receiving COMET over the waitlist in 2-week post-treatment depressive symptoms. In the 20% held-out test data, PAI did not interact with treatment to predict depression severity post-treatment (β = 0.880, SE = 1.21, t = -0.72, p = .47), indicating that our treatment matching algorithm was not able to provide statistically significant recommendations. Even in a large sample, personalized treatment recommendations for digital SSIs are difficult to develop.","PeriodicalId":54234,"journal":{"name":"Clinical Psychological Science","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13595997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149026893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reproducible Temperament Profiles in Adolescents With Attention-Deficit/Hyperactivity Disorder Prospectively Predict Clinical Outcomes. 青少年注意缺陷/多动障碍的可重复气质特征可预测临床结果。

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-09-01 Epub Date: 2026-08-25

Michael B Kozlowski, Jaden A Sangoi, Hannah E Morton, Elizabeth K Nousen, Jessica M Tipsord, McKenzie T Figuracion, Sarah Pieper, Madelyn Heise, Erica D Musser, Joel T Nigg, Sarah L Karalunas

{"title":"Reproducible Temperament Profiles in Adolescents With Attention-Deficit/Hyperactivity Disorder Prospectively Predict Clinical Outcomes.","authors":"Michael B Kozlowski, Jaden A Sangoi, Hannah E Morton, Elizabeth K Nousen, Jessica M Tipsord, McKenzie T Figuracion, Sarah Pieper, Madelyn Heise, Erica D Musser, Joel T Nigg, Sarah L Karalunas","doi":"","DOIUrl":"","url":null,"abstract":"Currently, the field faces controversy about how to integrate novel, trait-based dimensions into existing psychological diagnostic frameworks. The problem is salient for attention-deficit/hyperactivity disorder (ADHD), which encompasses a partially coherent neurodevelopmental syndrome that is nonetheless heterogeneous with respect to mechanism and outcomes. Here, we suggest that temperament profiles, related to trait-based variation in emotional response and regulation, provide a viable way to link the complexity of within-group trait variation to differences in clinical outcomes. Across two large, independent samples of adolescents with ADHD (Oregon ADHD-1000, ABCD) we identified largely reproducible temperament profiles: a high approach motivation profile (\"Surgent\") and a high negative emotion profile (\"Irritable\"). In both samples, the Irritable profile prospectively predicted worsening clinical outcomes over multiple years of longitudinal follow-up. Temperament profiling approaches can contribute to improved risk/resilience prediction among individuals with ADHD and help bridge dimensional models of psychopathology with developmental process and clinical decision-making.","PeriodicalId":54234,"journal":{"name":"Clinical Psychological Science","volume":"14 5","pages":"599-619"},"PeriodicalIF":5.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13580877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148992547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parent-Child Neural Dynamics during a Stressful Task: Probing Associations with Temperament and Anxiety. 压力任务中的亲子神经动力学：探究与气质和焦虑的关联。

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-09-01 Epub Date: 2026-08-25 DOI: 10.1177/21677026251396786

J Rocha-Hidalgo, H Nguyen, D Reis, D Schaedig, K I Thompson, S B Perlman, K E Pérez-Edgar

{"title":"Parent-Child Neural Dynamics during a Stressful Task: Probing Associations with Temperament and Anxiety.","authors":"J Rocha-Hidalgo, H Nguyen, D Reis, D Schaedig, K I Thompson, S B Perlman, K E Pérez-Edgar","doi":"10.1177/21677026251396786","DOIUrl":"10.1177/21677026251396786","url":null,"abstract":"Dynamic social interactions between parents and children can contribute to anxiety risk, amplifying shared genetic risk. Research has focused on observed behaviors to explain intergenerational transmission. Neural synchrony may contribute as a biological conduit for behavioral transmission of risk. We examined 109 parent-child dyads (M age=5.81 years; SD=1.2, 55 girls; 66 mothers) during a mildly stressful interaction (DB-DOS: BioSync), using fNIRS. Synchrony was lower during the Recovery block than during Baseline, with no significant differences between the Stressful and Baseline conditions. Synchrony significantly decreased in dyads with children higher in Effortful Control during Recovery, consistent with flexible adjustment after stress. Dyads with children higher in Fear showed reduced VLPFC synchrony during Recovery compared to Baseline. Higher parental state anxiety was associated with lower VLPFC synchrony. Neural synchrony may be sensitive to context, and individual traits linked to anxiety risk and resilience, providing potential targets for prediction and intervention.","PeriodicalId":54234,"journal":{"name":"Clinical Psychological Science","volume":"14 5","pages":"658-675"},"PeriodicalIF":5.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13556219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early Childhood Cumulative Risk and Temperament Predict Preadolescent Appraisal and Coping and Adolescent Psychopathology. 儿童早期累积风险和气质预测青春期前评价、应对和青少年精神病理。

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-09-01 Epub Date: 2026-08-25 DOI: 10.1177/21677026251398521

Michele R Smith, Caitlin Stavish, Autumn Eo, Ana Funes Gonzalez, Krystal H Parrish, Stephanie Thompson, Katie A McLaughlin, Liliana J Lengua

{"title":"Early Childhood Cumulative Risk and Temperament Predict Preadolescent Appraisal and Coping and Adolescent Psychopathology.","authors":"Michele R Smith, Caitlin Stavish, Autumn Eo, Ana Funes Gonzalez, Krystal H Parrish, Stephanie Thompson, Katie A McLaughlin, Liliana J Lengua","doi":"10.1177/21677026251398521","DOIUrl":"10.1177/21677026251398521","url":null,"abstract":"This study tested a model of early childhood adversity, temperament, and their interaction predicting appraisal (threat) and coping (active, avoidant) styles that increase risk for psychopathology (n = 306). Temperament was assessed at 3-5.5 years, appraisal and coping styles at 11-12 years, and internalizing and externalizing problems at 11-12 and 15-16 years. Threat was predicted by higher fear and cumulative risk x frustration interaction, which also predicted avoidance. High-frustration children demonstrated more threat and avoidance at lower levels of cumulative risk than children experiencing greater risk and those low in frustration. An effortful control x cumulative risk interaction predicted coping. Higher cumulative risk was related to more active and avoidant coping for low-effortful control children. Threat and coping were concurrently associated with preadolescent psychopathology, which predicted higher adolescent psychopathology. Such longitudinal models are critical to articulate the processes of risk for psychopathology in temperamentally vulnerable children exposed to adversity.","PeriodicalId":54234,"journal":{"name":"Clinical Psychological Science","volume":"14 5","pages":"709-730"},"PeriodicalIF":5.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13556355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of Early Temperament Profiles in Infants at Elevated Likelihood for Autism and Attention-Deficit/Hyperactivity Disorder. 自闭症和注意缺陷/多动障碍患儿早期气质特征的鉴定。

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-09-01 Epub Date: 2026-08-25 DOI: 10.1177/21677026251365933

Girija Kadlaskar, Ana-Maria Iosif, Sally Ozonoff, Meghan Miller

{"title":"Identification of Early Temperament Profiles in Infants at Elevated Likelihood for Autism and Attention-Deficit/Hyperactivity Disorder.","authors":"Girija Kadlaskar, Ana-Maria Iosif, Sally Ozonoff, Meghan Miller","doi":"10.1177/21677026251365933","DOIUrl":"10.1177/21677026251365933","url":null,"abstract":"Autism and attention-deficit/hyperactivity disorder (ADHD) likely share some common developmental pathways, suggesting the potential for overlapping early risk factors, including aspects of temperament. We employed a transdiagnostic, data-driven approach to identifying temperament-based subgroups at 12 and 18 months across infants at elevated and low genetic likelihood for autism and ADHD. Results revealed general continuity in early temperament, with many infants remaining in well-regulated/socially engaged subgroup (73%), while some (27%) showed shifts over time toward heightened negative reactivity, greater inhibition, and/or reduced social engagement during the toddler period. Importantly, not all infants/toddlers who later met criteria for autism or showed preschool concerns for ADHD demonstrated negative-reactive/inhibitory temperament traits during early development. However, certain temperament profiles were associated with autism and ADHD traits regardless of clinical outcome. Findings contribute to a better understanding of early transdiagnostic markers, and the nuanced developmental pathways related to autism and ADHD.","PeriodicalId":54234,"journal":{"name":"Clinical Psychological Science","volume":"14 5","pages":"556-574"},"PeriodicalIF":5.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13580874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148992497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations between maternal emotion dysregulation, infant negative affect and toddler mental health depend on newborn neurobehavioral profiles. 母亲情绪失调、婴儿负面影响和幼儿心理健康之间的关系取决于新生儿的神经行为特征。

IF 5.1 2区医学

Clinical Psychological Science Pub Date : 2026-09-01 Epub Date: 2026-08-25 DOI: 10.1177/21677026251380591

Anna M Zhou, Sarah E Maylott, Anna M Compton, Madeleine Bruce, Nicolette C Molina, K Lee Raby, Sheila E Crowell, Elisabeth Conradt

{"title":"Associations between maternal emotion dysregulation, infant negative affect and toddler mental health depend on newborn neurobehavioral profiles.","authors":"Anna M Zhou, Sarah E Maylott, Anna M Compton, Madeleine Bruce, Nicolette C Molina, K Lee Raby, Sheila E Crowell, Elisabeth Conradt","doi":"10.1177/21677026251380591","DOIUrl":"10.1177/21677026251380591","url":null,"abstract":"We investigated maternal emotion dysregulation and profiles of newborn neurobehavior as predictors of infant temperamental negative affect and toddler psychopathology risk among 385 mother-infant dyads from birth to 18-months postpartum. Our findings show support for multiple mechanisms by which transdiagnostic risk develops in early childhood. For infants in the low arousal, high lethargy newborn neurobehavior profile, infant negative affect was a pathway by which maternal emotion dysregulation was associated with toddler socioemotional difficulties. In contrast, maternal emotion dysregulation was directly associated with toddler behavior dysregulation for infants in the high arousal, high stress neurobehavior profile at birth. Newborns in the high attention, moderate regulation neurobehavior profile were buffered against the effects of maternal emotion dysregulation on infant negative affect and toddler psychopathology risk. Our findings highlight the importance of examining the combination of newborn neurobehaviors with maternal mental health to understand the development of psychopathology risk in early childhood.","PeriodicalId":54234,"journal":{"name":"Clinical Psychological Science","volume":"14 5","pages":"731-747"},"PeriodicalIF":5.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13556314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0