Nano Futures最新文献

{"title":"Synthesis and characterizations of sugar-glass nanoparticles mediated protein delivery system for tissue engineering application","authors":"Aniruddha Pal, R. Vel, Sk. Hasanur Rahaman, Somoshree Sengupta, S. Bodhak","doi":"10.1088/2399-1984/ac7832","DOIUrl":"https://doi.org/10.1088/2399-1984/ac7832","url":null,"abstract":"The present work focuses on the synthesis and characterization of a sugar-glass nanoparticle (SGnP) based reservoir type protein delivery system pertinent to tissue engineering applications. The SGnP nanocarriers were prepared via inverse micelle of sodium bis(2-ethylhexyl) sulfosuccinate based on an anionic surfactant and subsequent flash-freezing technique. Initially, a total of five different grades of protein-free SGnPs have been prepared to examine the effects of systematic changes in starting concentrations of the aqueous phase, organic solvent, the molar ratio of water, and surfactant in controlling the size, shape, and uniformity of micelles. Evidently, the Fourier transform infrared (FTIR) and scanning electron microscope (SEM) results confirmed that the SGnP can be successfully prepared. Subsequently, SGnP based protein depot has been validated using bovine serum albumin (BSA), horseradish peroxidase (HRP) and growth and differentiation factor-5 (GDF-5). The particle size, morphology, protein encapsulation efficiency and in vitro release kinetics were assessed using SEM, FTIR, UV–visible spectroscopy and Bradford protein assays. Excellent encapsulation efficiency (93%–94%) and sustained release behaviour of BSA (∼22% protein release after 14 d) and GDF-5 proteins (∼29% protein release after 30 d) were exhibited by the optimal grades of SGnP constructs with an average particle size of 266 nm and 93 nm, respectively. Furthermore, FTIR, differential scanning calorimeter (DSC), polyacrylamide gel electrophoresis (PAGE) and NATIVE-PAGE studies results confirm successful encapsulation, stability and preserving the structural integrity of proteins placed into the core of the SGnP constructs. Evidently, a very high (93%) residual HRP enzyme activity signifies the capability of our SGnP system to protect the encapsulated proteins from process-related stresses. In vitro cytotoxicity and fluorescence cell morphology analyses using human adipose-derived mesenchymal stem cells affirmed good cytocompatibility of protein encapsulated SGnP. Overall, the study findings indicate SGnP nanocarrier-mediated protein delivery systems as a promising approach complementary to conventional techniques in tissue engineering and therapeutic applications.","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42476310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electron beam lithography on non-planar, suspended, 3D AFM cantilever for nanoscale thermal probing","authors":"R. Swami, G. Julie, D. Singhal, J. Paterson, J. Maire, S. Le-Denmat, J. Motte, S. Gomes, O. Bourgeois","doi":"10.1088/2399-1984/ac7599","DOIUrl":"https://doi.org/10.1088/2399-1984/ac7599","url":null,"abstract":"Electron beam lithography (EBL) on non-planar, suspended, curved or bent surfaces is still one of the most frequently stated problems for fabricating novel and innovative nano-devices and sensors for future technologies. Although spin coating is the most widespread technique for electron resist (e-resist) deposition on 2D or flat surfaces, it is inadequate for suspended and 3D architectures because of its lack of uniformity. In this work, we use a thermally evaporated electron sensitive resist the QSR-5 and study its sensitivity and contrast behaviour using EBL. We show the feasibility of utilizing the resist for patterning objects on non-planar, suspended structures via EBL and dry etching processes. We demonstrate the integration of metal or any kind of thin films at the apex of an atomic force microscopy (AFM) tip. This is showing the great potential of this technology in various fields, such as magnetism, electronic, photonics, phononics and other fields related to near field microscopy using AFM probe like for instance scanning thermal microscopy.","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46538019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic nanoparticles and magnetic particle spectroscopy-based bioassays: a 15 year recap.","authors":"Kai Wu, Jinming Liu, Vinit Kumar Chugh, Shuang Liang, Renata Saha, Venkatramana D Krishna, Maxim C-J Cheeran, Jian-Ping Wang","doi":"10.1088/2399-1984/ac5cd1","DOIUrl":"10.1088/2399-1984/ac5cd1","url":null,"abstract":"<p><p>Magnetic nanoparticles (MNPs) have unique physical and chemical properties, such as high surface area to volume ratio and size-related magnetism, which are completely different from their bulk materials. Benefiting from the facile synthesis and chemical modification strategies, MNPs have been widely studied for applications in nanomedicine. Herein, we firstly summarized the designs of MNPs from the perspectives of materials and physicochemical properties tailored for biomedical applications. Magnetic particle spectroscopy (MPS), first reported in 2006, has flourished as an independent platform for many biological and biomedical applications. It has been extensively reported as a versatile platform for a variety of bioassays along with the artificially designed MNPs, where the MNPs serve as magnetic nanoprobes to specifically probe target analytes from fluid samples. In this review, the mechanisms and theories of different MPS platforms realizing volumetric- and surface-based bioassays are discussed. Some representative works of MPS platforms for applications such as disease diagnosis, food safety and plant pathology monitoring, drug screening, thrombus maturity assessments are reviewed. At the end of this review, we commented on the rapid growth and booming of MPS-based bioassays in its first 15 years. We also prospected opportunities and challenges that portable MPS devices face in the rapidly growing demand for fast, inexpensive, and easy-to-use biometric techniques.</p>","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531898/pdf/nihms-1799789.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10273867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanomaterials and printing techniques for 2D and 3D soft electronics","authors":"L. Migliorini, Sara Moon Villa, T. Santaniello, P. Milani","doi":"10.1088/2399-1984/ac74f9","DOIUrl":"https://doi.org/10.1088/2399-1984/ac74f9","url":null,"abstract":"The merging of electronically conductive elements with soft polymeric materials gave birth to the novel field of soft and stretchable electronics and robotics, in which the key aspect is the maintenance of electrical properties even under severe mechanical deformation. Here, we review the variety of fabrication techniques (dry, wet, and printed) that have been designed, studied, and tested, which leads to a forecast of how soft technologies will have a revolutionary impact on the progress of biomedicine and pre-clinical practice, wearable electronics, environmental monitoring and recognition, smart farming and precision agriculture, and energy harvesting and storage. A particular focus is given to techniques for the printing of 2D and 3D electronics, which allow compliant conductive elements to be coupled to complex three-dimensional objects and platforms. We discuss why it is now necessary to choose between different nanoscale building blocks, nanomaterials, and deposition techniques and to optimize such choices. The watchwords to be prioritized are scalability, versatility, environmental sustainability and biocompatibility, integration, and reduction of the fabrication steps. The target is the design of an eco-friendly and versatile approach for the fully additive manufacture of free-form advanced soft electronic devices (which will eventually be biocompatible and biodegradable) using a multilayer, multimaterial process that can print both active and passive 3D elements on soft polymeric platforms. The sequential combination of dry and wet spray printing is shown to be one of the most promising approaches.","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42524590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and characterization of a g-C3N4/TiO2-ZnO nanostructure for photocatalytic degradation of methylene blue","authors":"Sepide Saeidpour, B. Khoshnevisan, Z. Boroumand","doi":"10.1088/2399-1984/ac74fa","DOIUrl":"https://doi.org/10.1088/2399-1984/ac74fa","url":null,"abstract":"In this study, graphitic carbon nitride (g-C3N4) nanostructures with different molar ratios of ZnO and TiO2 (i.e. g-C3N4/TiO2, g-C3N4/ZnO, and g-C3N4/TiO2-ZnO) were synthesized. The synthesized samples were characterized using field-emission scanning electron microscopy (FE-SEM), x-ray diffraction, Brunauer–Emmett–Teller (BET) analysis, and ultraviolet (UV)–visible diffuse reflectance spectroscopy (UV-vis-DRS) techniques. The FE-SEM images showed the surface morphology of each sample. The UV-vis-DRS results indicated that the bandgap of TiO2 was reduced by adding g-C3N4 and different molar ratios of ZnO. The results obtained from BET analysis confirmed that the surface area of the g-C3N4/TiO2-ZnO (1:10) nanostructure was 97.494 cm2 g−1, which was comparatively higher than other nanostructures, and became suitable for photocatalytic activity. The photocatalytic activity of the g-C3N4/TiO2-ZnO nanostructure was performed by photo-degradation of methylene blue (MB) dye under simulated solar light. The results of the photocatalytic activity showed that the synthesized nanostructure had good degradation under UV and visible light irradiation by 94.6% and 62.4%, respectively. Also, the kinetics of the photocatalytic degradation confirmed that degradation of MB dye in the presence of UV light was faster than visible light. Furthermore, a study of the reusability of the nanostructure exhibited good photo-stability and activity after six runs.","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43000975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bipolar dual-broadband photodetectors based on perovskite heterojunctions","authors":"Yu Li, F. Guo, Shanshan Yu, Jian Wang, Shihe Yang","doi":"10.1088/2399-1984/ac7099","DOIUrl":"https://doi.org/10.1088/2399-1984/ac7099","url":null,"abstract":"The development of efficient photodetectors for color recognition is of great importance for many applications. In this paper, we report a novel bipolar dual-broadband photodetector equipped with a perovskite heterojunction, with bidirectional broadband responses in the short-wavelength and long-wavelength regions at zero bias voltage, enabled by a charge separation reversion mechanism. The unique aerosol–liquid–solid technique allowed the perovskite heterojunction to be fabricated by successively depositing wide-bandgap perovskite (WBP) and narrow-bandgap perovskite (NBP) layers directly on the transparent substrate. For photodetectors based on the perovskite heterojunctions, the short-wavelength photons were depleted by the bottom WBP layer and generated negative responses, while the long-wavelength photons were absorbed by the top NBP layer and generated positive responses. Moreover, the demarcation wavelength between the bipolar responses and the cut-off wavelength can be easily tuned by adjusting the bandgaps (or compositions) of the bottom and top perovskite layers.","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43621393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced water oxidation reaction activity of Mn3O4 nanocrystals in an alkaline medium by doping transition-metal ions","authors":"P. Saraswathi, Anjaly Babu, S. Ramarao, K. Uday Kumar, Hitesh Borkar, C. Rajesh, K. Kumar","doi":"10.1088/2399-1984/ac7098","DOIUrl":"https://doi.org/10.1088/2399-1984/ac7098","url":null,"abstract":"Designing low-cost, Earth-abundant, and non-precious catalysts for electrochemical water oxidation reactions is particularly important for accelerating the development of sustainable energy sources and, further, can be fed to fuel cells. In the present work, we report the oxygen evolution reaction (OER) activity of a metal-oxide catalyst, Mn3O4, and study the effect of transition metal doping (Cu and Fe) on the OER activity of Mn3O4 in an alkaline medium. The Mn3O4 and transition metal (Cu and Fe) doped Mn3O4 catalysts were prepared using a hydrothermal reaction technique. Powder x-ray diffraction studies revealed that these compounds adopt a tetragonal spinel structure with an I41/amd space group, and this is further supported with Fourier transform infrared spectroscopic measurements. These results are further supported by high-resolution transmission electron microscopic measurements. The electrochemical measurements of these catalysts reveal that the transition metal (Cu and Fe) doped Mn3O4 catalysts show better OER activity than pristine Mn3O4 (MO). The transition metal (Cu and Fe) doped Mn3O4 catalysts exhibit lower overpotential for the OER (η MCO = 300 mV and η MFO = 240 mV) than the MO (η MO = 350 mV) catalyst. The better performance of Fe-doped Mn3O4 is further supported by turnover frequency calculations.","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49367842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in nanomaterial-based biosensors for viral detection","authors":"Christian Harito, M. Khalil, N. L. W. Septiani, K. K. Dewi, A. Hardiansyah, B. Yuliarto, F. Walsh","doi":"10.1088/2399-1984/ac701d","DOIUrl":"https://doi.org/10.1088/2399-1984/ac701d","url":null,"abstract":"Pandemics such as COVID-19 have highlighted the importance of point-of-care sensors for testing, tracing, and treatment to minimize and manage infection. Biosensors have been widely deployed in portable devices such as glucose sensors and pregnancy tests. Their development for point-of-exposure virus detection or point-of-care devices is anticipated but their reliability for the accurate detection of viruses is critical. Nanomaterials, such as metal nanoparticles (NPs), magnetic NPs, quantum dots, carbon-based nanomaterials, and molecularly imprinted polymer (MIP) NPs, have been utilized in biosensors to enhance sensitivity. Molecular imprinting is a cost-effective method to synthesize polymers for selective binding, which have excellent properties as biosensors. More research on MIP NPs can be expected in the near future. The utilization of nanomaterials in several types of transducers for biosensor devices is also illustrated to give an overview of their use. Finally, a summary is given together with a future perspective on how biosensors can be further developed as reliable, portable viral biosensors.","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44431043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of the adsorptive removal of (Fe+2) and (Ni+2) from water by synthesized magnetite/corn cobs magnetic nanocomposite","authors":"Mohamed N Sanad, S. El-Dek, U. Eldemerdash, Mohamed M. ElFaham","doi":"10.1088/2399-1984/ac6a31","DOIUrl":"https://doi.org/10.1088/2399-1984/ac6a31","url":null,"abstract":"Heavy metals are principal concomitant pollutants in industrial wastewaters, posing a serious threat to public health and the environment. Herein, we develop a novel strategy to produce a new nanocomposite formed from corn cobs (CCs) and magnetite as a nanomaterial for the simultaneous removal of Fe+2 and Ni+2. The as-prepared nanocomposite was systematically characterized by x-ray diffraction, field emission scanning electron microscopy, mapping, energy-dispersive x-ray spectroscopy, high-resolution transmission electron microscopy, selected area electron diffraction, zeta size, and zeta potential. Compared to the CCs and Fe3O4, the nanocomposite showed better adsorption performance. The maximum adsorption efficiency of the CC, Fe3O4, and the nanocomposite was calculated by atomic analysis to be around 91.84%, 91.28%, and 98.51%, respectively, under the same conditions. This study indicates that the nanocomposite could be a favorable biomass-derived adsorbent for the simultaneous removal of heavy metals.","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2022-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49039939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent developments in functional triboelectric nanogenerators for flame-retardant, human health, and energy-harvesting fields: a crucial review","authors":"Ran Wang, Miaomiao Ji, X. Jin, Qiran Zhang, T. Jiao","doi":"10.1088/2399-1984/ac691c","DOIUrl":"https://doi.org/10.1088/2399-1984/ac691c","url":null,"abstract":"In recent years, the rational use and development of energy has become an important research direction. As a novel technology, triboelectric nanogenerators (TENGs) can effectively convert other energy from around the environment into electricity. TENGs have wide applicability due to their adjustable structures, but they are still limited to a certain extent in some special fields. For example, some special requirements for triboelectric materials need to be addressed when a TENG is applied in a high temperature environment, in water, in wind, or for human health. Therefore, this review introduces some TENGs applied in special environments, and provides a reference for the preparation and application of functional TENGs. It provides a new idea for the preparation of multifunctional TENGs and their wide application in various fields.","PeriodicalId":54222,"journal":{"name":"Nano Futures","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46025464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}