Eurasian Journal of Medicine最新文献_第4页

Temporal Assessment of Gadolinium Deposition and T1 Signal Intensity Changes in Rat Kidney with Single and Multiple Doses of Injection: An Experimental Study. 大鼠肾脏单剂量和多剂量注射钆沉积和 T1 信号强度变化的时间评估：一项实验研究

IF 0.9

Eurasian Journal of Medicine Pub Date : 2024-02-01 DOI: 10.5152/eurasianjmed.2024.23155

Fatih Alper, Adem Karaman, Ahmet Yalçın, Büşra Diyarbakır Şirinoğlu, Büşra Dinçer, Alptuğ Atila, Serhat Kaya, Taha Tavacı

{"title":"Temporal Assessment of Gadolinium Deposition and T1 Signal Intensity Changes in Rat Kidney with Single and Multiple Doses of Injection: An Experimental Study.","authors":"Fatih Alper, Adem Karaman, Ahmet Yalçın, Büşra Diyarbakır Şirinoğlu, Büşra Dinçer, Alptuğ Atila, Serhat Kaya, Taha Tavacı","doi":"10.5152/eurasianjmed.2024.23155","DOIUrl":"10.5152/eurasianjmed.2024.23155","url":null,"abstract":"Background: Gadolinium deposition in biological tissues was first reported in patients with renal failure. We aimed to investigate gadolinium deposition in the rat kidney after exposure to single and multiple doses of gadolinium and evaluate deposition for 1- and 3-month periods. We also aimed to determine any correlation between the amount of deposition and T1-weighted image intensity.Methods: Seventy rats (5 animals per group) were included in the sample, and 9 groups received a single dose (0.3, 0.6, and 1.2 mmol/kg) of gadolinium, and 1 group for each dose was sacrificed at the end of the first day, week, and month. Four groups received weekly doses (0.3 and 0.6 mmol/kg) and were sacrificed at the end of 6 and 12 weeks. Measurement of T1 intensities was carried out with postinjection images before sacrifice, and deposition was determined using inductively coupled plasma mass spectrometry.Results: The number of injections was associated with increased gadolinium deposition (P <.001) in the kidney. After the weekly injections, the deposited gadolinium levels did not significantly difer between the low and medium doses at the end of the sixth week (P=.067). There was no agreement between the observers regarding the measurement of T1 signal intensity in both single-dose and multidose experiments (P=.263 and P=.307, respectively).Conclusion: Deposition was dose dependent in the postinjection stage in contrast to the late stage in which deposition was not associated with dose or number of injections until the 12th week. T1 signal intensity measurement is unreliable for assessing deposition in the rat kidney.","PeriodicalId":53592,"journal":{"name":"Eurasian Journal of Medicine","volume":"56 1","pages":"47-51"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Spinal Needle Type on Post-Dural Puncture Headache in Spinal Anesthesia: Prospective Randomized Study. 脊髓麻醉中脊髓针类型对硬膜穿刺后头痛的影响：前瞻性随机研究

IF 0.9

Eurasian Journal of Medicine Pub Date : 2024-02-01 DOI: 10.5152/eurasianjmed.2024.23223

Duygu Akyol, Mine Çelik, Necmiye Ay, Güneş Özlem Yıldız

{"title":"The Effect of Spinal Needle Type on Post-Dural Puncture Headache in Spinal Anesthesia: Prospective Randomized Study.","authors":"Duygu Akyol, Mine Çelik, Necmiye Ay, Güneş Özlem Yıldız","doi":"10.5152/eurasianjmed.2024.23223","DOIUrl":"10.5152/eurasianjmed.2024.23223","url":null,"abstract":"Background: Postdural puncture headache is a headache that occurs after a dura puncture, especially in caesarean sections, and afects patient comfort and mobilization. In this study, we compared the efects of pencil-tipped spinal needles and especially curved, bilateral atraumatic spinal needles in individuals undergoing elective caesarean sections.Methods: A total of 886 patients, aged 20-50 years, who had cesarean sections with spinal anesthesia and had American Society of Anesthesiologists II and III scores, were included in the study. The patients were allocated into 3 groups using the closed envelope randomization technique: Group 1 (n=250) received spinal insertions using 25-gauge pencil-point needles; Group 2 (n=245) received spinal insertions using 26-gauge atraumatic needles; and Group 3 (n=250) received spinal insertions using 27-gauge pencil-point needles. Records were kept of the quantity of spinal needle referrals, the type of treatment, the length of hospital stays, and complications.Results: In the study, 745 patients who had cesarean section operations under spinal anesthesia were further analyzed. The mean incidence of post-dural puncture headache (PDPH) was 3.2% (n=24). The incidence of PDPH was higher in group 2 than in group 3 and group 1 (Group 1: 2.8%; Group 2: 6.8%; Group 3: 0%) (P <0.05). Among other complications, low back, back, shoulder, and surgical complications were similar for all 3 groups.Conclusion: In caesarean section operations, pencil-point spinal needles were found to have a lower incidence of postdural puncture headache than Atraucan-cut needles, regardless of needle thickness.","PeriodicalId":53592,"journal":{"name":"Eurasian Journal of Medicine","volume":"56 1","pages":"42-46"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Expression of Neurodegeneration-Related Genes in the Hippocampus of Hypothyroid Rats Following Long-Term Potentiation. 甲状腺功能减退大鼠海马体长期电位后神经变性相关基因的表达

IF 0.9

Eurasian Journal of Medicine Pub Date : 2024-02-01 DOI: 10.5152/eurasianjmed.2024.23133

Melek Altunkaya, Ercan Babur, Özlem Barutçu, Cem Süer, Nurcan Dursun

{"title":"The Expression of Neurodegeneration-Related Genes in the Hippocampus of Hypothyroid Rats Following Long-Term Potentiation.","authors":"Melek Altunkaya, Ercan Babur, Özlem Barutçu, Cem Süer, Nurcan Dursun","doi":"10.5152/eurasianjmed.2024.23133","DOIUrl":"10.5152/eurasianjmed.2024.23133","url":null,"abstract":"Background: In our research, we examined how the induction of long-term potentiation (LTP) in the hippocampus of hypothyroid rats afects the mRNA levels of several proteins involved with neurodegeneration, including Gsk3, Cdk5, Akt1, Mapt, P35 (Anxa), Capn1, Bace1, and Psen2.Methods: Wistar-albino rats, consisting of 12 males, were used in the research, and they were separated into 2 groups: control (n=6) and hypothyroidism (n=6). To induce hypothyroidism, propylthiouracil was added to drinking water at a dosage of 20 mg/kg/day. The test stimulus intensity was calculated, basal recordings were acquired, and LTP was induced by administering 100 Hz high-frequency stimulation (HFS) for 1 second with a 5-minute delay when the rats were aged 60 days. The population spike (PS) amplitude and excitatory postsynaptic potential (EPSP) slope were measured in the granule cell layer of the dentate gyrus. Using reverse transcription polymerase chain reaction, the mRNA levels of neurodegenerative genes were assessed in induced hippocampal tissues after the LTP protocol. The free T4 levels in plasma were measured using a plate reader with the commercial ELISA kit.Results: Following HFS, LTP was solely induced in the EPSP slope and PS amplitude in the control group. The impaired LTP response of the hypothyroidism group was accompanied by an increase in Akt1-mRNA expression and a decrease in Gsk3ß expression, whereas the value genes' mRNA expression levels did not difer significantly from those of the control group.Conclusion: The hypothyroidism-related LTP impairment could be caused by a reduction in PI3K/AKT signaling. Further investigation of this path is required to elucidate the pathophysiology of impaired synaptic plasticity in hypothyroidism.","PeriodicalId":53592,"journal":{"name":"Eurasian Journal of Medicine","volume":"56 1","pages":"21-26"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Approach and Anatomical Results in the Treatment of Retinopathy of Prematurity. 治疗早产儿视网膜病变的临床方法和解剖结果。

IF 0.9

Eurasian Journal of Medicine Pub Date : 2024-02-01 DOI: 10.5152/eurasianjmed.2024.23140

Mustafa Yıldırım

{"title":"Clinical Approach and Anatomical Results in the Treatment of Retinopathy of Prematurity.","authors":"Mustafa Yıldırım","doi":"10.5152/eurasianjmed.2024.23140","DOIUrl":"10.5152/eurasianjmed.2024.23140","url":null,"abstract":"Background: Retinopathy of prematurity (ROP) is a disease associated with abnormal development of retinal vessels in low birth weight and preterm infants. In this study, it was aimed to show that the disease can be controlled almost perfectly with early diagnosis and treatment in retinopathy developing in premature babies.Methods: In the study, 66 eyes of 33 patients who needed ROP treatment were evaluated. Babies who met the screening criteria were examined for the first time 3-4 weeks after birth. In the treatment of patients who underwent laser photocoagulation and intravitreal injection, the stage of the disease plus the regression of the disease in the laser group and completion of retinal vascularization in the intravitreal injection group were determined as success criteria.Results: Laser photocoagulation (LFC) was applied to 54 eyes, intravitreal bevacizumab (IVB) was applied to 8 eyes, and bilateral LFC+IVB was applied to 2 patients in the same session. Since there was no complete regression in the stage of the 2 patients who underwent LFC, an IVB injection was made into one eye of a patient and both eyes of the other patient. After the treatments, the disease regressed and retinal macular traction did not occur.Conclusion: It has been indicated that timely intervention in patients with treatment indications after regular screening for ROP can prevent possible blindness.","PeriodicalId":53592,"journal":{"name":"Eurasian Journal of Medicine","volume":"56 1","pages":"52-55"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of the Ultrasound-Guided Interfascial Injection Applied in Addition to Physical Therapy Applications in Chronic Low Back Pain: A Quasi-Experimental Study. 超声引导筋膜间注射与物理疗法相结合对慢性腰痛的疗效：一项准实验研究。

IF 0.9

Eurasian Journal of Medicine Pub Date : 2024-02-01 DOI: 10.5152/eurasianjmed.2024.23286

Burcu Metin Ökmen, Korgün Ökmen

{"title":"Effectiveness of the Ultrasound-Guided Interfascial Injection Applied in Addition to Physical Therapy Applications in Chronic Low Back Pain: A Quasi-Experimental Study.","authors":"Burcu Metin Ökmen, Korgün Ökmen","doi":"10.5152/eurasianjmed.2024.23286","DOIUrl":"10.5152/eurasianjmed.2024.23286","url":null,"abstract":"Background: Anatomical and histological features of the thoracolumbar fascia may play an active role in chronic low back pain (LBP). This study aimed to evaluate the efcacy of interfascial injection in patients with LBP.Methods: Sixty participants with chronic LBP were recruited for this study. The patients were allocated to 2 groups: physical therapy (PT) (n=30) and PT+interfascial injection (IFI) (n=31, 10mL (0.25% bupivacaine)+methylprednisolone (40 mg) injection into the middle layer between the quadratus lumborum and erector spinae muscle). Outcome measures involved performing Numeric Rating Scale (NRS) and Oswestry Disability Index (ODI) scoring on study participants at pretreatment (PRT), as well as posttreatment at months first, second, fourth, and sixth.Results: In both groups, NRS and ODI scores were statistically significantly lower than PRT values at the first, second, third, fourth, and sixth months. (P <.05) NRS and ODI scores were significantly lower in the IFI and PT groups compared to the PT group at the first, second, fourth, and sixth months. (P <.05).Conclusion: The study result shows that IFI applied to the middle layer of the thoracolumbar fascia may be efective in individuals with chronic LBP. The efect of fascial structures on LBP should be further investigated.","PeriodicalId":53592,"journal":{"name":"Eurasian Journal of Medicine","volume":"56 1","pages":"56-60"},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141918098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Bacteriocins on the Intestinal Microbiota. 细菌素对肠道微生物群的影响

IF 0.9

Eurasian Journal of Medicine Pub Date : 2023-12-01 DOI: 10.5152/eurasianjmed.2023.23393

Selin Doğan, Taha Yasin Koç, Mehmet Karadayı

引用次数: 0

The Shining Star of the Last Decade in Regional Anesthesia Part-II: Interfascial Plane Blocks for Cardiac, Abdominal, and Spine Surgery. 区域麻醉十年来的耀眼之星第二部分：心脏、腹部和脊椎手术的科间平面阻滞。

IF 1.5

Eurasian Journal of Medicine Pub Date : 2023-11-02 DOI: 10.5152/eurasianjmed.2023.23015

Ahmet Murat Yayık, Erkan Cem Çelik, Muhammed Enes Aydın, Elif Oral Ahıskalıoğlu, Burhan Dost, Başak Altıparmak, Madan Narayanan, Alessandro De Cassai, Serkan Tulgar, Ali Ahıskalıoğlu

引用次数: 0

Comparing Capitonnage and Uncapitonnage Techniques for Pulmonary Hydatid Cysts: A Systematic Review and Meta-analysis. 肺棘球蚴囊顶切除术和非囊顶切除技术的比较：系统综述和荟萃分析。

IF 1.5

Eurasian Journal of Medicine Pub Date : 2023-11-02 DOI: 10.5152/eurasianjmed.2023.22281

Yener Aydın, Kamber Kasalı, Ali Bilal Ulaş, Ayşenur Dostbil, İlker İnce, Atilla Eroglu

{"title":"Comparing Capitonnage and Uncapitonnage Techniques for Pulmonary Hydatid Cysts: A Systematic Review and Meta-analysis.","authors":"Yener Aydın, Kamber Kasalı, Ali Bilal Ulaş, Ayşenur Dostbil, İlker İnce, Atilla Eroglu","doi":"10.5152/eurasianjmed.2023.22281","DOIUrl":"10.5152/eurasianjmed.2023.22281","url":null,"abstract":"Surgery is the primary treatment for pulmonary hydatid cysts. This systematic review and meta-analysis aimed to compare the results of capitonnage and uncapitonnage techniques for the surgery of pulmonary hydatid cysts. Descriptive Boolean queries were used to search PubMed, Scopus, and Web of Science for articles published up to June 2022 to evaluate the outcomes of pulmonary hydatid cysts in terms of mortality, postoperative complications, and hospital stay. A total of 12 studies were included. An analysis of the total side effects revealed that there was a statistically significant difference between the capitonnage and uncapitonnage groups (odds ratio=3.81, 95% confidence interval=[1.75-8.31], P < .001). The results showed that more side effects were observed in the uncapitonnage group than in the capitonnage group. The risk of side effects in the uncapitonnage group is 3.81 times higher than in the capitonnage group. The results showed that more prolonged air leak was seen in uncapitonnage group than in the capitonnage group (odds ratio=4.18, 95% confidence interval=[1.64-10.64], P=.003). The results show that more empyema was observed in uncapitonnage group than in the capitonnage group (odds ratio=4.76, 95% confidence interval=[1.29-17.57], P =0.020). An analysis of atelectasis and mean hospital stay revealed that there was no statistically significant difference between the capitonnage and uncapitonnage groups. The results reveal the advantages of capitonnage in the treatment of pulmonary hydatid cysts and that the capitonnage method is quite effective in reducing complications compared to the uncapitonnage method.","PeriodicalId":53592,"journal":{"name":"Eurasian Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11075026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71429140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pityriasis Lichenoides et Varioliformis Acuta Case with Enterobiasis, Giardiasis, and Helicobacter pylori Infection. 尖锐苔藓样和Varioliformis糠疹合并肠病、贾第鞭毛虫病和幽门螺杆菌感染病例。

IF 1.5

Eurasian Journal of Medicine Pub Date : 2023-10-27 DOI: 10.5152/eurasianjmed.2023.23026

Mehmet Melikoğlu, Büşra Solak Esen, Rabia Yamak, Ali İşlek

引用次数: 0

Changes in the Urethral Artery After Experimental Subarachnoid Hemorrhage-Induced Injury of the Pudendal Ganglion and Onuf’s Nucleus Junction 实验性蛛网膜下腔出血致阴部神经节及Onuf核连接处损伤后尿道动脉的变化

Eurasian Journal of Medicine Pub Date : 2023-10-26 DOI: 10.5152/eurasianjmed.2023.23202

引用次数: 0