International Journal of Women''s Dermatology最新文献

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Current management of skin conditions in Kenya: exploring teledermatology preferences and perspectives among providers. 肯尼亚皮肤状况的当前管理:探索远程皮肤科的偏好和提供者之间的观点。
International Journal of Women''s Dermatology Pub Date : 2025-02-06 eCollection Date: 2025-03-01 DOI: 10.1097/JW9.0000000000000196
Jennifer M Fernandez, Hashim Kaderbhai, Jennifer L Adams, Mary B Adam, Rodney D Adam
{"title":"Current management of skin conditions in Kenya: exploring teledermatology preferences and perspectives among providers.","authors":"Jennifer M Fernandez, Hashim Kaderbhai, Jennifer L Adams, Mary B Adam, Rodney D Adam","doi":"10.1097/JW9.0000000000000196","DOIUrl":"10.1097/JW9.0000000000000196","url":null,"abstract":"<p><strong>Background: </strong>Teledermatology programs may help expand access to care for skin conditions in areas that are underserved by dermatologists such as sub-Saharan Africa, but their success requires input from participating providers.</p><p><strong>Objective: </strong>This study assesses teledermatology preferences among healthcare providers in Kenya.</p><p><strong>Methods: </strong>An anonymous cross-sectional survey of nondermatology providers was conducted in Kenya from January to March 2024 at Aga Khan University Hospital-Nairobi and Kijabe Hospital.</p><p><strong>Results: </strong>Among the 38 providers, 81.6% were physicians. Patient population was primarily Fitzpatrick skin types V and VI. Almost all (97.4%) regularly encountered patients with skin disorders, yet only 5.3% felt comfortable diagnosing and treating 80 to 100% of these disorders independently. Providers anticipated referring cases of rashes (76.3%), unclear diagnoses (63.2%), and infectious diseases (50%), among others, for teledermatology consultation. Only 10.5% reported utilizing teledermatology, although the majority believed it would be useful (91.9%) and improve patient care (89.5%). Preferred response time was <24 hours (81.6%). Most favored submitting cases via personal cell phones (86.8%), with 87.9% preferring submission through WhatsApp.</p><p><strong>Limitations: </strong>Participants owned smartphones. The survey was distributed via WhatsApp.</p><p><strong>Conclusion: </strong>Nearly all providers in Kenya see patients with skin conditions, but few utilize teledermatology services. Teledermatology could be extremely beneficial for patients and providers seeking dermatologic expertise.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"11 1","pages":"e196"},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The risks of pityriasis rosea in pregnancy: a review. 妊娠期玫瑰糠疹的风险:综述。
International Journal of Women''s Dermatology Pub Date : 2025-01-16 eCollection Date: 2025-03-01 DOI: 10.1097/JW9.0000000000000191
Sophia Manduca, Christina S Oh, Michael Ong, Shari R Lipner, Miriam K Pomeranz, Amy K Bieber
{"title":"The risks of pityriasis rosea in pregnancy: a review.","authors":"Sophia Manduca, Christina S Oh, Michael Ong, Shari R Lipner, Miriam K Pomeranz, Amy K Bieber","doi":"10.1097/JW9.0000000000000191","DOIUrl":"10.1097/JW9.0000000000000191","url":null,"abstract":"<p><strong>Objective: </strong>This review aims to consolidate available evidence, identify research gaps, and advocate for a more informed approach to the management of pityriasis rosea in pregnant individuals.</p><p><strong>Data sources: </strong>PubMed, Web of Science, and Directory of Open Access Journals were systematically searched based on the keywords \"pityriasis rosea,\" \"pityriasis circinate,\" \"roseola annulate,\" \"herpes tonsurans maculosus,\" \"herald patch,\" and \"pregnancy\" on January 25, 2024 for publications between 1950 to 2024.</p><p><strong>Study selection: </strong>Studies containing outcomes data for pregnant patients with established PR were included. Studies must have been written or translated into English and published in a peer-reviewed journal. Studies which did not pertain to PR in the setting of pregnancy were excluded, as screened by two reviewers. Responses, general informational reviews, and letters to the editor without novel data were also excluded.</p><p><strong>Results: </strong>Eleven relevant articles were identified, encompassing data from 177 patients. Overall, 81% of patients had favorable outcomes while 19% experienced unfavorable outcomes. PR onset before 15 weeks gestation was associated with a higher rate of unfavorable outcomes (41%), including a 27% rate of spontaneous abortion (SA). Conversely, PR onset after 15 weeks had a lower unfavorable outcome rate (21%), and no instances of SA.</p><p><strong>Conclusion: </strong>Conflicting data exists regarding the impact of PR on pregnancy outcomes. However, PR onset within the first 15 weeks, widespread lesions, constitutional symptoms, and higher human herpesvirus 6 viral loads may increase the risk of unfavorable outcomes such as SA. Close follow-up and consideration of antiviral treatment are recommended for high-risk patients.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"11 1","pages":"e191"},"PeriodicalIF":0.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nevus of Hori in African patients: an entity that is most likely underdiagnosed in clinical practice. 非洲患者的黑痣:一个在临床实践中最有可能被误诊的实体。
International Journal of Women''s Dermatology Pub Date : 2025-01-06 eCollection Date: 2025-03-01 DOI: 10.1097/JW9.0000000000000190
Frans Maruma, Ncoza Dlova, Thabiso Rafaki Petrus Mofokeng, Boitshoko Claudia Moloabi
{"title":"Nevus of Hori in African patients: an entity that is most likely underdiagnosed in clinical practice.","authors":"Frans Maruma, Ncoza Dlova, Thabiso Rafaki Petrus Mofokeng, Boitshoko Claudia Moloabi","doi":"10.1097/JW9.0000000000000190","DOIUrl":"10.1097/JW9.0000000000000190","url":null,"abstract":"<p><strong>Background: </strong>Nevus of Hori (HN) has been primarily reported in patients of Eastern Asian descent, with a paucity of data regarding HN occurring in African patients. In this study, we report on South African patients with HN initially thought to have melasma.</p><p><strong>Objective: </strong>To characterize the histopathological and clinical phenotypes of HN in African patients.</p><p><strong>Methods: </strong>Retrospective data were collected from patients who met the inclusion criteria. These data entailed the clinical distribution, demographic data, Fitzpatrick skin phototype, and histopathologic features of African patients diagnosed with HN from a single private aesthetic center in Bloemfontein, South Africa.</p><p><strong>Results: </strong>Thirty patients with an average age of 49 ± 7.37 were included in this analysis. The majority of patients were female (<i>n</i> = 29; 96.67%), and most patients were of Fitzpatrick skin phototype V (<i>n</i> = 22; 73.3%). The most common clinical distribution pattern was bitemporal (76.7%), followed by the zygomatic pattern (20%), mixed type (16.7%), and finally the central forehead pattern (3.3%). Histopathologically, the dendritic cell type of melanocytes was observed in the majority of patients (<i>n</i> = 25; 83.3%), while spindle-shaped cells were observed in few patients (<i>n</i> = 7; 23.33%), and none of the patients had bipolar-type melanocytes.</p><p><strong>Limitations: </strong>This study has limitations inherent to small sample size and its inability to accurately generalize the findings.</p><p><strong>Conclusion: </strong>HN can clinically mimic melasma in African patients. The most common clinical presentation was bitemporal. To our knowledge, this study is the largest regarding the clinicopathological profile of HN in African patients and it is likely to be the first to report these compelling findings.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"11 1","pages":"e190"},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of psoriasis in women 18 to 45 years of age in Australia and Japan: insights from patient and dermatologist surveys. 澳大利亚和日本18至45岁女性牛皮癣的管理:来自患者和皮肤科医生调查的见解。
International Journal of Women''s Dermatology Pub Date : 2025-01-02 eCollection Date: 2025-03-01 DOI: 10.1097/JW9.0000000000000189
Yukie Yamaguchi, Lynda Spelman, Yoko Mizutani, Bartosz Lukowski, Alfred Lanzafame, Annika Smith
{"title":"Management of psoriasis in women 18 to 45 years of age in Australia and Japan: insights from patient and dermatologist surveys.","authors":"Yukie Yamaguchi, Lynda Spelman, Yoko Mizutani, Bartosz Lukowski, Alfred Lanzafame, Annika Smith","doi":"10.1097/JW9.0000000000000189","DOIUrl":"10.1097/JW9.0000000000000189","url":null,"abstract":"<p><strong>Background: </strong>A psoriasis (PSO) diagnosis may pose specific treatment challenges for women of childbearing age (WoCBA) who are considering pregnancy, are pregnant, or have just given birth.</p><p><strong>Objective: </strong>To report perspectives of WoCBA with PSO regarding pregnancy and dermatologists about the disease management of these women in Australia and Japan.</p><p><strong>Methods: </strong>Online surveys were completed by women aged 18 to 45 years who were pregnant within the past 5 years with moderate to severe PSO and dermatologists.</p><p><strong>Results: </strong>In Japan (<i>n</i> = 31) and Australia (<i>n</i> = 27), most WoCBA with PSO did not feel adequately informed about pregnancy planning and had concerns regarding the safety of tumor necrosis factor inhibitors (TNFi) when used during pregnancy. Dermatologists (Australia: <i>n</i> = 40; Japan: <i>n</i> = 97) also had safety concerns around prescribing TNFi during pregnancy, and most were impartial toward or not at all comfortable with prescribing TNFi to women who were pregnant or actively planning pregnancy. Dermatologists felt that more safety data on pregnancy, lactation, and pediatric outcomes 5 years postdelivery would increase their comfort with prescribing TNFi.</p><p><strong>Limitations: </strong>Limitations included small respondent size, a lack of formal validation for questionnaires, recall bias among participants, and generalizability of results to all WoCBA with PSO. Response rates of survey participants were also not collected.</p><p><strong>Conclusion: </strong>Additional safety information can help address concerns about biologic use (including TNFi) in WoCBA, enabling dermatologists to make informed treatment recommendations in such patients.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"11 1","pages":"e189"},"PeriodicalIF":0.0,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11688090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient perspectives towards skin of color clinics: results from a survey study. 患者对有色人种诊所的看法:一项调查研究的结果。
International Journal of Women''s Dermatology Pub Date : 2024-10-17 eCollection Date: 2024-10-01 DOI: 10.1097/JW9.0000000000000182
Severine Cao, Reinie Thomas, Meghan Mansour, Juliana L Ramirez, Grace Hile, Mari Paz Castanedo-Tardan, Milad Eshaq
{"title":"Patient perspectives towards skin of color clinics: results from a survey study.","authors":"Severine Cao, Reinie Thomas, Meghan Mansour, Juliana L Ramirez, Grace Hile, Mari Paz Castanedo-Tardan, Milad Eshaq","doi":"10.1097/JW9.0000000000000182","DOIUrl":"10.1097/JW9.0000000000000182","url":null,"abstract":"<p><strong>Background: </strong>Skin of color clinics (SOCCs) are dermatology clinics that provide specialized care for patients with melanated skin. Little is known about patient perceptions and attitudes toward these clinics.</p><p><strong>Objective: </strong>We sought to perform a survey study to assess the opinions of patients of color previously seen in our dermatology department toward SOCC.</p><p><strong>Methods: </strong>A 14-question survey was sent by email to patients of color seen at our institution between January 1, 2015 and December 31, 2021.</p><p><strong>Results: </strong>Out of 264 participants who completed the survey, 176 (66.7%) indicated they would prefer to be seen in a SOCC and 88 (33.3%) preferred to be seen in a general dermatology clinic (GDC). Clinic choice varied significantly by ethnicity, with Black/African American participants being the most likely to prefer SOCC over GDC than other races/ethnicities. Those interested in SOCC were primarily motivated by a search for expertise in the skin of color (SOC) and did not have a preference for the skin color of the SOCC dermatologist. Those interested in GDC were happy with their current care.</p><p><strong>Limitations: </strong>This study was limited by the single-center design and sample bias.</p><p><strong>Conclusion: </strong>Our results overall provide positive patient feedback for the creation of SOCCs as centers for expertise in SOC. The preference for SOCC varied by race/ethnicity, highlighting that clinic choice is best left to the patient.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 3","pages":"e182"},"PeriodicalIF":0.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lichenoid drug reaction to technicium-99: a case report and review of the literature. 锝-99引起的苔藓样药物反应:病例报告和文献综述。
International Journal of Women''s Dermatology Pub Date : 2024-09-18 eCollection Date: 2024-10-01 DOI: 10.1097/JW9.0000000000000179
Emily Kozera, Tania Elhage, Adrian Cachia, John W Frew
{"title":"Lichenoid drug reaction to technicium-99: a case report and review of the literature.","authors":"Emily Kozera, Tania Elhage, Adrian Cachia, John W Frew","doi":"10.1097/JW9.0000000000000179","DOIUrl":"10.1097/JW9.0000000000000179","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 3","pages":"e179"},"PeriodicalIF":0.0,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11410317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinicopathologic features, demographics, disease burden, and therapeutics in alopecic sarcoidosis: a case series and systematic review. 脱发肉样瘤病的临床病理特征、人口统计学、疾病负担和疗法:病例系列和系统综述。
International Journal of Women''s Dermatology Pub Date : 2024-09-13 eCollection Date: 2024-10-01 DOI: 10.1097/JW9.0000000000000181
Chinemelum Obijiofor, Michelle Sikora, Ata S Moshiri, Mariam Alam, Kristen I Lo Sicco, Sotonye Imadojemu, Avrom S Caplan
{"title":"Clinicopathologic features, demographics, disease burden, and therapeutics in alopecic sarcoidosis: a case series and systematic review.","authors":"Chinemelum Obijiofor, Michelle Sikora, Ata S Moshiri, Mariam Alam, Kristen I Lo Sicco, Sotonye Imadojemu, Avrom S Caplan","doi":"10.1097/JW9.0000000000000181","DOIUrl":"10.1097/JW9.0000000000000181","url":null,"abstract":"<p><strong>Background: </strong>Alopecic sarcoidosis is an uncommon cutaneous manifestation of sarcoidosis. Scarring and nonscarring alopecic sarcoidosis have been reported; however, information on the epidemiology, systemic disease associations, and treatment efficacy is limited.</p><p><strong>Objective: </strong>To address these gaps, we conducted a retrospective chart review and systematic literature review of alopecic sarcoidosis cases.</p><p><strong>Methods: </strong>Full-text English publications from PubMed, Scopus, and Google Scholar from inception to August 2023 were analyzed. Treatment evidence quality was assessed using the modified Oxford Centre for Evidence-Based Medicine rating scale. Three patients with biopsy-proven alopecic sarcoidosis were included as a case series, all demonstrating systemic sarcoidosis and 2 requiring multiple therapies. Among 1778 search results, 60 articles representing 77 cases of alopecic and scalp sarcoidosis were included. Patients were categorized into 4 distinct alopecic subgroups. Black patients constituted the majority of all subgroups.</p><p><strong>Results: </strong>Extracutaneous sarcoidosis burden was high across all alopecic subgroups, with ocular disease appearing overrepresented. Topical and oral corticosteroids were the main treatments. Though scarring alopecia patients had poor outcomes despite receiving immunomodulators/cx, limited data suggest potential efficacy of tumor necrosis factor-alpha inhibitors.</p><p><strong>Limitations: </strong>This study has a small sample size.</p><p><strong>Conclusion: </strong>Our findings underscore the importance of evidence-based strategies for improving alopecic sarcoidosis management. Prompt diagnosis and systemic evaluation, especially for scarring alopecia, are essential for timely intervention to optimize patient outcomes.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 3","pages":"e181"},"PeriodicalIF":0.0,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11398751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient needs in women of childbearing age with psoriasis: retrospective analysis from the German PsoBest registry. 育龄妇女银屑病患者的需求:德国 PsoBest 登记处的回顾性分析。
International Journal of Women''s Dermatology Pub Date : 2024-09-11 eCollection Date: 2024-10-01 DOI: 10.1097/JW9.0000000000000176
Neuza da Silva Burger, Matthias Augustin, Lukas Westphal, Laura Kühl, Brigitte Stephan, Rachel Sommer
{"title":"Patient needs in women of childbearing age with psoriasis: retrospective analysis from the German PsoBest registry.","authors":"Neuza da Silva Burger, Matthias Augustin, Lukas Westphal, Laura Kühl, Brigitte Stephan, Rachel Sommer","doi":"10.1097/JW9.0000000000000176","DOIUrl":"10.1097/JW9.0000000000000176","url":null,"abstract":"<p><strong>Background: </strong>Women of childbearing age (WoCBA) with psoriasis face additional burden related to contraindications of systemic treatments during pregnancy/lactation and to the physical and psychosocial impact of psoriasis on their intimate/sexual relationships.</p><p><strong>Objective: </strong>Within a people-centered health care model, this study aimed to identify specific patient needs and their correlates in WoCBA (18-45 years), in comparison to same-age men and women above 45 years.</p><p><strong>Methods: </strong>Baseline data from the German PsoBest registry, including patients with moderate/severe plaque-type psoriasis with the indication for systemic therapy, were retrospectively analyzed. Psoriasis severity was assessed with the Psoriasis Area and Severity Index and patient-reported outcomes included EuroQoL Visual Analogue Scale, Dermatology Life Quality Index (DLQI), and Patient Needs Questionnaire.</p><p><strong>Results: </strong>The participants were 2308 WoCBA, 3634 men between 18 and 45 years of age, and 3401 women older than 45 years. In comparison to both control groups, WoCBA reported more DLQI impairments and higher needs to reduce social impairments (eg, \"to be able to lead a normal working life\"; \"to be less burdened in your partnership\"; \"to be able to have a normal sex life\"). These patient needs were associated with having psoriasis arthritis, previous systemic therapy, worse general health, and more DLQI impairments.</p><p><strong>Limitations: </strong>Retrospective analysis of an established dataset limited the examination of specific developmental, sexual, and reproductive variables.</p><p><strong>Conclusion: </strong>The specific needs of WoCBA with psoriasis were particularly related to the work context/financial stability and intimate relationships, which are crucial aspects in family planning. These results claim for a sex/age-sensitive approach in the psoriasis health care, by considering these needs as qualifiers in the clinical decision for systemic treatment.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 3","pages":"e176"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11390045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alopecia patterns and trichoscopic findings in patients with autosomal recessive congenital ichthyosis. 常染色体隐性遗传先天性鱼鳞病患者的脱发模式和三镜检查结果。
International Journal of Women''s Dermatology Pub Date : 2024-08-21 eCollection Date: 2024-10-01 DOI: 10.1097/JW9.0000000000000175
Anissa Zaouak, Wafa Jouini, Ghaith Abdessalem, Sonia Abdelhak, Houda Hammami, Cherine Charfeddine, Samy Fenniche
{"title":"Alopecia patterns and trichoscopic findings in patients with autosomal recessive congenital ichthyosis.","authors":"Anissa Zaouak, Wafa Jouini, Ghaith Abdessalem, Sonia Abdelhak, Houda Hammami, Cherine Charfeddine, Samy Fenniche","doi":"10.1097/JW9.0000000000000175","DOIUrl":"10.1097/JW9.0000000000000175","url":null,"abstract":"<p><strong>Background: </strong>Autosomal recessive congenital ichthyosis (ARCI) is a rare genodermatosis categorized among nonsyndromic ichthyoses. While ARCI patients often manifest hair abnormalities, their impact on the quality of life remains underreported in the literature.</p><p><strong>Objective: </strong>This study aims to comprehensively characterize the clinical and trichoscopic findings of alopecia in ARCI patients.</p><p><strong>Methods: </strong>A prospective study spanning from January 2019 to December 2021 (3 years) was conducted at the Dermatology Department of Habib Thameur Hospital, Tunis, Tunisia. Clinical and trichoscopic examinations were performed on the hair of the participants, with molecular studies conducted on 15 patients.</p><p><strong>Results: </strong>The study included 30 patients, predominantly female (male/female = 0.58), with a mean age of 20 years. Twenty-eight patients were born from consanguineous marriages. Lamellar ichthyosis was observed in 22 cases, while congenital ichthyosiform erythroderma and bathing suit ichthyosis were each present in 4 cases. The ARCI severity score, assessed using the Visual Index For Ichthyosis Severity scale, had a mean value of 15 (4-28). Alopecia emerged as a prominent finding in 11 patients, presenting as hairline recession (13%), multiple patchy alopecia (27%), and alopecia of the eyebrows (13%). Trichoscopic findings included interfollicular and perifollicular scaling, perifollicular lamellar hyperkeratosis, peripilar casts, interfollicular erythema, loss of hair openings, predominance of single hair follicles, broken hair, vellus hair, anisotrichosis, pili torti, dystrophic hair, and comma hair. Several trichoscopic findings showed statistically significant associations with the severity of ARCI.</p><p><strong>Limitations: </strong>In our study, we only included 30 patients due to the rarity of this genodermatosis.</p><p><strong>Conclusion: </strong>Contrary to previous perceptions, alopecia is a notable finding in ARCI, particularly in patients with a severe form. This study provides a detailed characterization of alopecia in ARCI, shedding light on its prevalence and associated trichoscopic features, thereby enhancing our understanding of this dermatological condition.</p>","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 3","pages":"e175"},"PeriodicalIF":0.0,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11338256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiovascular adverse event reporting in psoriasis and psoriatic arthritis biological therapy clinical trials. 银屑病和银屑病关节炎生物疗法临床试验中的心血管不良事件报告。
International Journal of Women''s Dermatology Pub Date : 2024-08-19 eCollection Date: 2024-10-01 DOI: 10.1097/JW9.0000000000000172
Sreejan Saha, Molly Ottensoser, Brittany N Weber, Jeffrey S Berger, Michael S Garshick
{"title":"Cardiovascular adverse event reporting in psoriasis and psoriatic arthritis biological therapy clinical trials.","authors":"Sreejan Saha, Molly Ottensoser, Brittany N Weber, Jeffrey S Berger, Michael S Garshick","doi":"10.1097/JW9.0000000000000172","DOIUrl":"10.1097/JW9.0000000000000172","url":null,"abstract":"","PeriodicalId":53478,"journal":{"name":"International Journal of Women''s Dermatology","volume":"10 3","pages":"e172"},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11332718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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