{"title":"Attitudes of Oral Surgeons and Periodontists towards Immediate Dental Implant Placement.","authors":"Zemyna Bineviciute, Gintaras Juodzbalys","doi":"10.5037/jomr.2024.15203","DOIUrl":"10.5037/jomr.2024.15203","url":null,"abstract":"<p><strong>Objectives: </strong>This cross-sectional study aimed to evaluate the factors that determine the choice of oral surgeons and periodontists to perform immediate dental implant placement.</p><p><strong>Material and methods: </strong>An anonymous survey was carried out from January 6, 2024 to February 29, 2024. The questionnaire was distributed online to Lithuanian specialists - oral surgeons and periodontists, who perform implantation procedures. A total of 186 professionals were included in this survey. Chi-square test, its degrees of freedom was used for the analysis of variables.</p><p><strong>Results: </strong>The main reason for refusing immediate implant placement is a periapical lesion greater than 5 mm, reported by 91.7% of oral surgeons and 96.9% of periodontists. Good aesthetics and preservation of anatomical structures are identified as an advantage by 99.2% of oral surgeons and 92.3% of periodontists. In the aesthetic zone, for periodontists, the main criterion for choosing a method is the quantitative and qualitative indicators of the soft tissue of the extraction socket 96.9%, and for oral surgeons - the morphology of the bone walls of the socket 87.6%. Only 43.1% of periodontists and 33.9% of oral surgeons are familiar with and use extraction socket morphology assessment classifications for immediate dental implant placement.</p><p><strong>Conclusions: </strong>Taking into account study's results, it is recommended to adjust the teaching programs at Universities and to increase the knowledge of specialists performing dental implantation procedures, by carrying out continuous educational programs.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 2","pages":"e3"},"PeriodicalIF":1.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oren Babich, Erel Lugassy, Michael Babich, Pinny Abayov, Eliezer Haimov, Gintaras Juodzbalys
{"title":"The Use of Platelet-Rich Fibrin in Sinus Floor Augmentation Surgery: a Systematic Review.","authors":"Oren Babich, Erel Lugassy, Michael Babich, Pinny Abayov, Eliezer Haimov, Gintaras Juodzbalys","doi":"10.5037/jomr.2024.15201","DOIUrl":"10.5037/jomr.2024.15201","url":null,"abstract":"<p><strong>Objectives: </strong>This systematic review aims to critically assess the impact of platelet-rich fibrin on maxillary sinus floor augmentation and outline the specific aspects of new bone formation, bone height, implant stability quotient, and Schneiderian membrane thickness.</p><p><strong>Material and methods: </strong>A systematic review and meta-analysis were conducted, analysing studies from MEDLINE (PubMed), the Cochrane Library, and ScienceDirect databases, published from January 29, 2018 until January 29, 2024 that compared maxillary sinus floor augmentation (MSFA) using bone graft material with and without platelet-rich fibrin (PRF). This review focused on patients 18 years and older who undergone MSFA before the dental implant placement. It systematically examined five studies, encompassing randomized controlled trials, and reported on 112 MSFA procedures conducted in 84 patients.</p><p><strong>Results: </strong>The meta-analysis reveals a marginal significance in new bone formation with PRF, suggesting a trend towards beneficial outcomes that were not statistically significant. No significant impact on bone height was observed. However, a notable improvement in implant stability quotient (ISQ) was recorded, indicating enhanced implant stability with PRF. The Schneiderian membrane thickness did not show significant changes post-treatment with PRF.</p><p><strong>Conclusions: </strong>While platelet-rich fibrin shows promise in enhancing implant stability, its effects on new bone formation and Schneiderian membrane thickness are inconclusive, highlighting the need for further research. Platelet-rich fibrin did not significantly affect bone height. The findings support platelet-rich fibrin's potential as a beneficial adjunct in maxillary sinus floor augmentation, particularly for implant stability.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 2","pages":"e1"},"PeriodicalIF":1.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nelli Yildirimyan, Mehmet Ali Altay, İrem Hicran Özbudak
{"title":"Can CAPRIN-1 Be Responsible for the Recurrence Potential of Odontogenic Keratocysts?","authors":"Nelli Yildirimyan, Mehmet Ali Altay, İrem Hicran Özbudak","doi":"10.5037/jomr.2024.15204","DOIUrl":"10.5037/jomr.2024.15204","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this retrospective study is to compare dentigerous cysts and odontogenic keratocysts for cytoplasmic activation/proliferation - associated protein-1 antibodies via immunohistochemical staining to obtain a new perspective about the specific behavioural characteristics of odontogenic keratocysts at the molecular level.</p><p><strong>Material and methods: </strong>Forty dentigerous cysts (DC) and forty odontogenic keratocysts (OKC) tissue samples were examined using immunohistochemical staining to detect cytoplasmic activation/proliferation - associated protein-1 (CAPRIN-1) antibodies. Nuclear and/or cytoplasmic staining was evaluated as \"positive\". Cell staining rate (%) and cell staining intensity were determined, and a staining intensity distribution (SID) score was calculated for each sample. Cases were considered \"negative\" if they showed no staining for CAPRIN-1 antibodies, thus were given a SID score of zero. According to the SID scores, the expression levels were rated as negative, mild, moderate, or high.</p><p><strong>Results: </strong>Of 80 samples, 16 that could adversely affect immunohistochemical evaluation were excluded. Ten negative, 21 positive and three negative, 30 positive CAPRIN-1 expressions were observed in DC and OKC groups, respectively. The difference between the negative and positive cases within groups was significant only in the OKC group (P = 0.000). The SID score range and mean were 0 to 160 and 31.1 (SD 35.7) for DC and 0 to 160 and 57.3 (SD 42.3) for OKC groups. CAPRIN-1 expression was significantly higher in the OKC group (P = 0.043).</p><p><strong>Conclusions: </strong>The molecular basis for increased mitotic activity, high recurrence rates or presence of satellite cysts in odontogenic keratocysts may be attributed to the expression of cytoplasmic activation/proliferation - associated protein-1.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 2","pages":"e4"},"PeriodicalIF":1.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pinny Abayov, Rafael Sarikov, Lisa-Marie Nazarenko, Oren Babich, Eliezer Haimov, Gintaras Juodzbalys
{"title":"Outcome Difference between Short and Longer Dental Implants Placed Simultaneously with Alveolar Bone Augmentation: a Systematic Review and Meta-Analysis.","authors":"Pinny Abayov, Rafael Sarikov, Lisa-Marie Nazarenko, Oren Babich, Eliezer Haimov, Gintaras Juodzbalys","doi":"10.5037/jomr.2024.15202","DOIUrl":"10.5037/jomr.2024.15202","url":null,"abstract":"<p><strong>Objectives: </strong>This systematic review and meta-analysis aim to provide detailed insights into the clinical performance of short and longer dental implants placed simultaneously with bone augmentation.</p><p><strong>Material and methods: </strong>The search for literature was performed across MEDLINE (PubMed), ScienceDirect and the Cochrane Library databases, adhering to specific selection criteria and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Only articles published in English between 2014 and 2024 were considered for data collection. Primary outcomes were survival rate (SR), marginal bone loss (MBL) and complications. Clinical outcomes were as follows: bleeding on probing (BOP), periodontal pocket depth (PPD), and implant stability quotient (ISQ). Quality and risk of bias assessment were evaluated by the Critical Appraisal Checklist tool for randomized controlled trials developed by the Joanna Briggs Institute.</p><p><strong>Results: </strong>A total of 14678 articles were screened, with 9 meeting the inclusion criteria and being utilized for this systematic review and meta-analysis. A total of 495 patients with 984 implants (491 short and 493 longer implants) showing a SR of 93.91% for the short implants and 91.83% for the longer implants. Meta-analysis revealed statistically significant difference between short implants and longer implants simultaneously placed with alveolar bone augmentation in relation to MBL (-0.513 mm, 95% CI = -0.93 to -0.096; P = 0.02), and in PPD (-0.247, 95% CI = -0.515 to 0.022; P = 0.07).</p><p><strong>Conclusions: </strong>When comparing the results of treatment with short and longer dental implants combined with alveolar bone augmentation, short implants showed better clinical results regarding the parameters of survival rate, marginal bone loss and complications.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 2","pages":"e2"},"PeriodicalIF":1.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141977170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Frequency and Clinical Significance of Incidental Findings on CBCT Imaging: a Retrospective Analysis of Full-Volume Scans.","authors":"Charis Theodoridis, Spyros Damaskos, Christos Angelopoulos","doi":"10.5037/jomr.2024.15105","DOIUrl":"10.5037/jomr.2024.15105","url":null,"abstract":"<p><strong>Objectives: </strong>This retrospective study aims to identify incidental findings in cone-beam computed tomography scans of patients irradiated for preoperative evaluation for implant placement and obtained using the same imaging unit as well as the same field of view. The incidence of each incidental finding, as well as the overall incidence, were calculated and the findings were ranked according to their clinical significance.</p><p><strong>Material and methods: </strong>A total of 741 cone-beam computed tomography (CBCT) examinations with extended field of view (15 x 15 cm) were retrospectively evaluated for incidental findings (IFs). These were identified, recorded, classified as to their location, and ranked according to their clinical significance.</p><p><strong>Results: </strong>The vast majority of CBCT examinations presented at least one IF, resulting in a surprisingly high prevalence in total. If extreme anatomical variants are considered (nasal septum deviation, sinus septations etc.), the cumulative prevalence exceeds 99%. IFs of major significance, that may require immediate attention, are beyond 10% in frequency.</p><p><strong>Conclusions: </strong>We found high prevalence of incidental findings on cone-beam computed tomography examinations performed for preoperative evaluation for implant placement (99.5% if anatomical variants included). Most incidental findings were of minor significance. Although the number of incidental findings that require immediate attention is relatively low, there is a considerable number of cases that need periodic evaluation and/or referral.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 1","pages":"e5"},"PeriodicalIF":0.0,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141175980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Organic and Inorganic Nanoparticles on Colour Stability and Mechanical Properties of Heat Vulcanised Maxillofacial Silicone Elastomer: a Comparative Study.","authors":"Manisha Khanna, Komal Sehgal, Shefali Singla, Virender Kumar","doi":"10.5037/jomr.2024.15104","DOIUrl":"10.5037/jomr.2024.15104","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this comparative study <i>in vitro</i> was to evaluate the effect of organic and inorganic nanoparticles on colour stability, tear strength and hardness of maxillofacial silicone elastomer at baseline and when subjected to outdoor weathering for 6 months.</p><p><strong>Material and methods: </strong>A total of 240 specimens were fabricated using M511 platinum silicone which were divided into total 4 groups (n = 60) based on the type of nanoparticles (control, polytetrafuoroethylene [PTFE], titanium dioxide [TiO<sub>2</sub>], zinc oxide [ZnO]) added and each group was further divided into 3 subgroups (n = 20) for colour, tear strength (TS) and hardness (H) testing. The tests were conducted and data was obtained both before and after outdoor weathering of 6 months.</p><p><strong>Results: </strong>Minimum colour change after weathering was observed in PTFE group (∆E = 2.23). TiO<sub>2</sub> group showed maximum TS (12.01 N/mm) followed by PTFE group (10.85 N/mm) before weathering. After weathering, maximum TS was shown by TiO<sub>2</sub> group (12.9 N/mm) and PTFE group (12.54 N/mm). TiO<sub>2</sub> group showed maximum hardness (24.15 shore A) before weathering and PTFE group showed maximum hardness (33.43 shore A) after weathering.</p><p><strong>Conclusions: </strong>Within the limitations of this study, it can be concluded that the addition of polytetrafuoroethylene nanoparticles to the polymer enhances both the optical as well as mechanical properties and can be considered favourable for the extended life of the prosthesis.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 1","pages":"e4"},"PeriodicalIF":0.0,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Repetition Rate of Scanning Due to Motion Artefacts in Cone-Beam Computed Tomography: a Retrospective Study.","authors":"Fahrettin Kalabalık, Emre Aytuğar, Fatoş Aykanat, Ceren Çiftçi","doi":"10.5037/jomr.2024.15106","DOIUrl":"10.5037/jomr.2024.15106","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this retrospective study was to investigate the incidence of repeated cone-beam computed tomography scans due to motion artefacts in a Turkish subpopulation.</p><p><strong>Material and methods: </strong>A total of 6364 patients' cone-beam computed tomography data were analysed retrospectively to identify repeated scans due to motion artefacts. Patients were divided into eight age groups: 1) < 10-year-olds, 2) 10 to 19-year-olds, 3) 20 to 29-year-olds, 4) 30 to 39-year-olds, 5) 40 to 49-year-olds, 6) 50 to 59-year-olds, 7) 60 to 69-year-olds, and 8) > 70 year-olds. Chi-square test was applied to evaluate the repetition rate of scans by age and gender groups. Statistical significance was set at P < 0.05.</p><p><strong>Results: </strong>Repeated scans due to motion artefacts were observed in 1.96% of the patients. The repetition rate of scans was significantly higher in males than in females (P = 0.006). Furthermore, the repetition rate of scans was significantly higher in patients < 10 years old compared to the other age groups. However, there was no significant difference in the repetition rate of scans due to motion artefacts among the other age groups (P > 0.05).</p><p><strong>Conclusions: </strong>The present findings suggest that patient age and gender are associated with repeated cone-beam computed tomography scans due to motion artefacts. Males and children under the age of 10 had more common repeated scans due to motion artefacts.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 1","pages":"e6"},"PeriodicalIF":0.0,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristian Kniha, Joud Alhares, Stephan Christian Möhlhenrich, Marie Sophie Katz, Philipp Winnand, Frank Hölzle, Ali Modabber, Marius Heitzer
{"title":"Dental Implant Placement in the Maxilla Following Ridge Augmentation with Free Iliac Bone Graft and Oral Rehabilitation with Fixed Prosthesis: a Three-Year Follow-Up Study.","authors":"Kristian Kniha, Joud Alhares, Stephan Christian Möhlhenrich, Marie Sophie Katz, Philipp Winnand, Frank Hölzle, Ali Modabber, Marius Heitzer","doi":"10.5037/jomr.2024.15103","DOIUrl":"10.5037/jomr.2024.15103","url":null,"abstract":"<p><strong>Objectives: </strong>This prospective follow-up study aimed to evaluate the stability values of tapered titanium implants inserted into maxilla following ridge augmentation with free iliac bone graft and crestal bone changes up to three years of follow-up.</p><p><strong>Material and methods: </strong>A total of seven patients with 34 tapered titanium implants in the maxilla with fixed protheses were enrolled in this prospective follow-up study. Patients with previously augmented maxillae using free iliac bone grafts were included. Implant stability was measured (Osstell™) for up to three months of healing. Peri-implant bone resorption was measured using radiographic images taken immediately after implant surgery and after three years. Using a clinical and radiological examination survival and success rates were evaluated.</p><p><strong>Results: </strong>After implant insertion, the stability was 60.93, whereas the stability increased significantly (P = 0.0192) to 64.97 at implant exposure (after 3 months). The mean bone loss around the implants was 1.13 mm after three years. Clinical parameters revealed a mean sulcus depth of 2.76 (1.18) mm and a bleeding on probing score of 0.29 (0.58). The survival rate was 100%, and the success rate was 67.65% at the end of the study.</p><p><strong>Conclusions: </strong>Tapered implants can be used in free iliac bone grafts for fixed dentures. Implant stability values were high after insertion. In terms of a success rate of 67.65%, the patient's jaw reconstruction indicated a reduced implant success when comparing the data with healthy patients without any augmentation procedures.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 1","pages":"e3"},"PeriodicalIF":0.0,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141175862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Gingival Pigmentation and Related Factors on Former Smokers.","authors":"Samir Goyushov, Cihan Ateş, Süleyman Emre Meşeli","doi":"10.5037/jomr.2024.15102","DOIUrl":"10.5037/jomr.2024.15102","url":null,"abstract":"<p><strong>Objectives: </strong>Gingival pigmentation, the most common etiological factor of which is smoking, is a clinical condition that causes aesthetic complaints. Due to the dose-dependent effect of smoking, gingival pigmentation may present regression following cessation. This cross-sectional study aimed to evaluate gingival pigmentation in former tobacco consumers and compare with current ones.</p><p><strong>Material and methods: </strong>A total of 110 people, 70 of whom were current smokers (Group CS) and 40 of whom were former smokers (Group FS), were included in the study. Participants filled out the data collection forms containing questions on demographic features and information related to tobacco consumption. In addition, all individuals were examined with Hedin's melanin index (HMI) to evaluate gingival pigmentation. Statistical significance was set at the P < 0.05 level.</p><p><strong>Results: </strong>The population consisted of 57.3% male, and the mean age of all participants was 39.43 (SD 12.3) years. The mean duration of tobacco consumption did not differ between groups, whereas the mean HMI score of Group FS was significantly lower (P = 0.001). The correlation analyses showed that while the HMI score of Group CS was in relation to both daily consumption amount and duration of consumption (for both, P < 0.01), the HMI score of Group FS showed a negative association with only time elapsed after cessation (P = 0.000).</p><p><strong>Conclusions: </strong>Considering the limitations of this study, the outcomes revealed a dose- and a time-dependent relation of gingival pigmentation in smokers. However, gingival pigmentation in former tobacco consumers was negatively correlated only with time elapsed after cessation.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 1","pages":"e1"},"PeriodicalIF":0.0,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emil Hyldahl, Klaus Gotfredsen, Anne Marie Lynge Pedersen, Simon Storgård Jensen
{"title":"Survival and Success of Dental Implants in Patients with Autoimmune Diseases: a Systematic Review.","authors":"Emil Hyldahl, Klaus Gotfredsen, Anne Marie Lynge Pedersen, Simon Storgård Jensen","doi":"10.5037/jomr.2024.15101","DOIUrl":"10.5037/jomr.2024.15101","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this systematic review is to disclose the impact of autoimmune diseases and their medical treatment on dental implant survival and success.</p><p><strong>Material and methods: </strong>A literature search was conducted using MEDLINE (PubMed), The Cochrane Library and Embase up to December 6<sup>th</sup>, 2021. Any clinical study on patients with an autoimmune disease in whom implant therapy was performed was eligible. The quality of included studies was assessed using the Newcastle-Ottawa Scale. For each autoimmune disease group, data synthesis was divided into three groups: 1) overall results of the autoimmune disease, 2) overall results of corresponding control groups and 3) overall results of the autoimmune disease with a concomitant autoimmune disease (a subgroup of group 1). Descriptive statistics were used.</p><p><strong>Results: </strong>Of 4,865 identified articles, 67 could be included and mainly comprising case reports and retrospective studies with an overall low quality. Implant survival rate was 50 to 100% on patient and implant level after a weighted mean follow-up of 17.7 to 68.1 months. Implant success was sporadically reported. Data on immunosuppressive medication were too heterogeneously reported to allow detailed analysis.</p><p><strong>Conclusions: </strong>Overall, a high implant survival rate was reported in patients with autoimmune diseases. However, the identified studies were characterized by a low quality. No conclusions could be made regarding implant success and the effect of immunosuppressants due to heterogeneous reporting.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 1","pages":"e1"},"PeriodicalIF":0.0,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141176078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}