Lucia Lopez-Chaichio, Pablo Galindo-Moreno, Miguel Padial-Molina, Lourdes Gutierrez-Garrido, Roque Rodriguez-Alvarez, Francisco O'Valle, Andres Catena
{"title":"Mastication Influences Human Brain Anatomy.","authors":"Lucia Lopez-Chaichio, Pablo Galindo-Moreno, Miguel Padial-Molina, Lourdes Gutierrez-Garrido, Roque Rodriguez-Alvarez, Francisco O'Valle, Andres Catena","doi":"10.5037/jomr.2024.15404","DOIUrl":"10.5037/jomr.2024.15404","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this observational clinical study was to evaluate the relationship between brain anatomical and volumetric changes in white matter, grey matter, and cerebral cortex thickness with the number of functional occlusal pairs present in the mouth.</p><p><strong>Material and methods: </strong>The number of functional occlusal pairs in 70 patients was counted and non-invasive brain analysis was performed using magnetic resonance imaging. The volume of grey matter, white matter, and thickness of the cortex in different areas of the brain were determined by SPM12 and CAT12 software. Multiple regression model corrected for multiple comparisons using FDR and Spearman correlation coefficient were calculated for statistical comparison.</p><p><strong>Results: </strong>A total of 70 (39 male, 31 female) were analysed, with an average number of occlusal pairs of 10.21 (3.99). According to the Spearman correlation coefficient, a lower number of occlusal pairs was related to a reduction in white matter (right external capsule and posterior limb of the internal capsule), a reduction in grey matter (right temporal superior and medial gyrus and left <i>cerebellum crus</i> 1) and a reduction in thickness of the cerebral cortex (rostral anterior cingulated cortex of the right hemisphere and areas in the right and left hemisphere, especially in the frontal cortex).</p><p><strong>Conclusions: </strong>The number of occlusal pairs is related to the volume of white matter, grey matter, and thickness of the cerebral cortex in areas of the brain that are directly involved in the onset and progression of Alzheimer's disease and other dementias.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 4","pages":"e4"},"PeriodicalIF":1.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Kouri, Erofili Papadopoulou, Styliani Tziveleka, Dimitrios Velonis, Maria Georgaki, Evangelia Piperi, Emmanouil Vardas, Nikolaos G Nikitakis
{"title":"Aphthous-Like Stomatitis in a Patient Receiving Panitumumab.","authors":"Maria Kouri, Erofili Papadopoulou, Styliani Tziveleka, Dimitrios Velonis, Maria Georgaki, Evangelia Piperi, Emmanouil Vardas, Nikolaos G Nikitakis","doi":"10.5037/jomr.2024.15405","DOIUrl":"10.5037/jomr.2024.15405","url":null,"abstract":"<p><strong>Background: </strong>Panitumumab is an anti-epithelial growth factor receptor monoclonal antibody, approved for the treatment of metastatic colorectal cancer. Panitumumab has been more commonly associated with skin toxicity; oral adverse events have been scarcely reported in the literature. Herein, we present a case report of panitumumab-associated aphthous-like stomatitis.</p><p><strong>Methods: </strong>A 58 years old female visited the Oral Oncology Unit complaining of severe oral pain. The patient had been diagnosed with colon cancer metastatic to the liver and was receiving panitumumab (every 14 days) concurrently with irinotecan and 5-fluorouracil.</p><p><strong>Results: </strong>Clinical examination revealed multiple aphthous-like ulcers on the ventral surface and lateral borders of the tongue, lower lip and mucolabial fold, buccal mucosa and soft palate. Dexamethasone oral solution 0.5 mg/5 ml was topically administered t.i.d. along with tramadol 50 mg per os t.i.d. for pain management. One week later, the pain was relieved and the ulcers were almost completely healed. Tramadol administration was discontinued and dexamethasone was tapered during the following 8 days. There was no need for discontinuation of panitumumab. In close follow-up for the next four months, no painful oral symptomatology was reported.</p><p><strong>Conclusions: </strong>Anti-epithelial growth factor receptor agents are associated with oral adverse events that may cause severe pain, even necessitating discontinuation of the antineoplastic treatment. The implementation of preventive measures, early diagnosis, proper treatment and close monitoring of patients receiving anti-epithelial growth factor receptor agents are mandatory in order to preserve patients' quality of life and their compliance to therapeutic regimen.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 4","pages":"e5"},"PeriodicalIF":1.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aine Jakonyte, Vykintas Pliavga, Gintaras Juodzbalys
{"title":"A Comprehensive Analysis of the Association between Thyroid Dysfunctions and Periodontal Health: Systematic Review.","authors":"Aine Jakonyte, Vykintas Pliavga, Gintaras Juodzbalys","doi":"10.5037/jomr.2024.15401","DOIUrl":"10.5037/jomr.2024.15401","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this systematic literature review was to establish a correlation between thyroid dysfunctions and periodontium health.</p><p><strong>Material and methods: </strong>The systematic review was conducted according to PRISMA statement. An electronic search was performed using MEDLINE (PubMed) and Google Scholar databases using a combination of keywords \"hypothyroidism\", \"hypothyroidism\", \"thyroid\", \"thyroid dysfunction\" and \"periodontitis\". The research covered the period from January 1, 2019 and July 1, 2024, included studies written in English, conducted in humans.</p><p><strong>Results: </strong>The results showed that hyperthyroidism can be associated with a higher prevalence of periodontitis due to decreased oral microbiome diversity, serum thyroid-stimulating hormone levels, increased periodontal pocket depth, clinical attachment loss and interleukin-6. Hyperparathyroidism after parathyroidectomy may lead to a slightly higher risk of tooth extraction in the first two years afterward because decreasing lamina dura, increasing periodontal ligament width. And hypothyroidism negatively affects the homeostasis of calcium and phosphorus in the oral fluid and can change the composition of bone minerals.</p><p><strong>Conclusions: </strong>Hyperthyroidism increases the risk of periodontitis by promoting deeper periodontal pockets, reducing oral microbiome diversity, altering alveolar bone structure and elevating inflammatory markers like interleukin-6, which are linked to disease progression. Hypothyroidism worsens periodontal disease by disrupting calcium-phosphorus balance and causing alveolar bone changes, especially in young individuals. Both conditions affect periodontal homeostasis, emphasizing the bidirectional relationship between endocrine and periodontal health. Dentists should monitor thyroid dysfunction, as managing thyroid levels may improve periodontal treatment.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 4","pages":"e1"},"PeriodicalIF":1.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Interrelation between Cortical Bone Thickness and Primary and Secondary Dental Implant Stability: a Systematic Review.","authors":"Halah Al-Juboori, Zygimantas Petronis, Dainius Razukevicius","doi":"10.5037/jomr.2024.15402","DOIUrl":"10.5037/jomr.2024.15402","url":null,"abstract":"<p><strong>Objectives: </strong>Dental implants have emerged as a reliable and long-lasting solution for missing teeth, offering advantages over traditional prosthetic options. The aim of this systematic review was to thoroughly explore the correlation between cortical bone thickness of the jaws and bone-level dental implant primary and secondary stability.</p><p><strong>Material and methods: </strong>A comprehensive literature search was conducted in MEDLINE (PubMed), ClinicalKey and the Cochrane Library from 1 January, 2019 to 21 June, 2024. This review focused on patients undergoing dental implant placement with varying cortical bone thicknesses and implant stability levels. Quality and risk-of-bias assessment evaluated by Cochrane risk of bias tool.</p><p><strong>Results: </strong>Out of 160 screened articles, 28 were reviewed in full, and 6 met the inclusion criteria, involving 209 patients and 418 implants. Implant stability quotient (ISQ) values showed no significant correlations during baseline and secondary assessments (P > 0.05). Correlations were noted between implant stability, bone density, alveolar ridge width, and implant size (P < 0.01). ISQ and insertion torque value (ITV) were strongly correlated at insertion (P < 0.001) but not at follow-ups (P = 0.059 at 2 months, P = 0.817 at 6 months, P = 0.029 at 12 months). ISQ values increased over time (P < 0.001). Implants in native bone showed higher ISQ values at baseline (P = 0.011), 8 weeks (P = 0.013), and 12 weeks (P < 0.001). Regions with thicker cortical bone demonstrated superior primary stability.</p><p><strong>Conclusions: </strong>Thicker cortical bone enhances primary implant stability, as indicated by higher insertion torque and implant stability quotient values.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 4","pages":"e2"},"PeriodicalIF":1.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Osteocalcin Level in Gingival Crevicular Fluid in Periodontal Intrabony Defects Treated with Autologous Platelet Rich Fibrin: Non-Randomized Experimental Study.","authors":"Sahana Srinivas, Shruthi Sethuraman, Nisha Krishnavilasom Jayakumari","doi":"10.5037/jomr.2024.15403","DOIUrl":"10.5037/jomr.2024.15403","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this non-randomized experimental study is to evaluate and correlate the gingival crevicular fluid osteocalcin levels with clinical and radiographic parameters in patients with intrabony defects treated with autologous platelet-rich fibrin.</p><p><strong>Material and methods: </strong>Thirty intrabony defects in 14 patients were treated with autologous platelet-rich fibrin with open flap debridement. Clinical and radiographic parameters were recorded at baseline and 9 months postsurgery. Gingival crevicular fluid (GCF) was collected prior to the surgery, 3 months, 6 months and 9 months postsurgery and was analysed for levels of osteocalcin using ELISA.</p><p><strong>Results: </strong>All the clinical and radiographic parameters like plaque index (2.41 to 1.38) and gingival index (2.37 to 1.4) scores, probing pocket dept (6.43 to 3.78 mm), clinical attachment level (7.25 to 4.61 mm), relative attachment level (10.35 to 7.42 mm) and vertical depth (7.46 to 4.9), alveolar crest height (6.2 to 5.9), area of the defect (17.8 to 14.5) respectively showed improvement which was statistically significant (P < 0.001) except for the defect width (8.86 to 8.77) with P = 0.39. A moderate negative correlation was established between the GCF osteoclcin levels and the clinical and radiographic parameters at baseline and 9 months except for the % of defect fill which showed moderate positive correlation at 9 months (r = 0.55, P = 0.002).</p><p><strong>Conclusions: </strong>The gingival crevicular fluid osteocalcin can serve as a potential bone turnover biomarker in periodontal regeneration. In addition platelet-rich fibrin has made it possible to define natural bone regeneration as well as improve the clinical and radiological parameters.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 4","pages":"e3"},"PeriodicalIF":1.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic Utility of Immunofluorescence in Oral Lesions: a Systematic Review.","authors":"Selva Arockiam, Barath Raj, Nandini Prabha, Munusamy Dharani","doi":"10.5037/jomr.2024.15302","DOIUrl":"10.5037/jomr.2024.15302","url":null,"abstract":"<p><strong>Objectives: </strong>This systematic review aims to evaluate the diagnostic utility of direct and indirect immunofluorescence of oral lesions in comparison with conventional diagnostic aids.</p><p><strong>Material and methods: </strong>The diagnostic utility of immunofluorescence in various oral lesions was evaluated. Relevant data from 37 studies, including study characteristics, patient population, test details, and outcomes, were systematically extracted. The search was performed analysing studies across multiple electronic databases including MEDLINE (PubMed), Embase, Scopus and Google Scholar, published from January 15, 2024 until May 15, 2024. Risk of bias was assessed using a modified QUADAS-2 tool.</p><p><strong>Results: </strong>Most studies demonstrated a low risk of bias in most domains, indicating overall methodological rigor. Comparative analysis showed that direct immunofluorescence (DIF) consistently outperformed indirect immunofluorescence. DIF exhibited high sensitivity and specificity for pemphigus vulgaris (87.8% and 100%), mucous membrane pemphigoid (92% and 98%), and desquamative gingivitis oral ulcers overlapping with oral lichen planus (OLP) (81% and 98.9%). For OLP, DIF showed moderate sensitivity (64.3%) and high specificity (88%).</p><p><strong>Conclusions: </strong>This review highlights the superior diagnostic utility of direct immunofluorescence over indirect immunofluorescence in evaluating oral lesions. Direct immunofluorescence's higher performance makes it the preferred technique for conditions requiring direct visualization of tissue-bound immune deposits. The combined use of direct immunofluorescence and indirect immunofluorescence can enhance the evaluation and management of various oral pathologies.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 3","pages":"e2"},"PeriodicalIF":1.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ksenija Matvijenko, Alma Pranckeviciene, Rokas Borusevicius
{"title":"Impact of Different Dental Implant Alloys and Coating Materials on the Health of Tissues Surrounding Implants: a Systematic Literature Review.","authors":"Ksenija Matvijenko, Alma Pranckeviciene, Rokas Borusevicius","doi":"10.5037/jomr.2024.15301","DOIUrl":"10.5037/jomr.2024.15301","url":null,"abstract":"<p><strong>Objectives: </strong>Recently surface modification techniques have been introduced to dental implants to improve osseointegration, bone formation at the implant surface, and to reduce the occurrence of mucositis and peri-implantitis. The aim of this systematic literature review was to investigate the dependence of the risk of inflammation of the tissues surrounding the implant on different implant alloys and surface coating materials.</p><p><strong>Material and methods: </strong>The search for the systematic review of the scientific literature was performed between November 28, 2023, and February 5, 2024. Articles were retrieved using the PRISMA screening system from MEDLINE (PubMed), EMBASE (ScienceDirect), Cochrane Central Register of Controlled Trials (the Cochrane Library), Springer Link, and Google Scholar databases. The literature review included publications in English, randomized controlled clinical trials assessing bleeding on probing, pocket depth, and marginal bone level around the implant.</p><p><strong>Results: </strong>A total of 41 full-text articles were selected after removing duplicates, of which 5 were included in this systematic literature review. The data from the studies were structured and presented in summary tables. Statistically significant differences in marginal bone level loss were observed using fluoride and sandblasting with large grit and acid-etching methods for implant surface modification. However, the effects of other surface coating materials and different implant alloys on bone loss, bleeding on probing, and pocket depth were not found to be significant.</p><p><strong>Conclusions: </strong>Despite the limitations of this literature review, it can be concluded that implant alloys and surface coating materials are potential risk factors for the development of inflammation in the tissues surrounding the implant.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 3","pages":"e1"},"PeriodicalIF":1.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Renata Escapini Fanchiotti, Eline Manhães Reid Silva, Brenda Lamônica Rodrigues de Azevedo, Willian Grassi Bautz, Liliana Aparecida Pimenta de Barros, Letícia Nogueira da Gama de Souza
{"title":"Fibrosis in Oral Carcinoma and Leukoplakia: an Immunohistochemical Study.","authors":"Renata Escapini Fanchiotti, Eline Manhães Reid Silva, Brenda Lamônica Rodrigues de Azevedo, Willian Grassi Bautz, Liliana Aparecida Pimenta de Barros, Letícia Nogueira da Gama de Souza","doi":"10.5037/jomr.2024.15303","DOIUrl":"10.5037/jomr.2024.15303","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this retrospective study was to evaluate clinicopathologic profile and collagen type I expression in oral leukoplakia and oral squamous cell carcinoma to elucidate stromal alterations in malignant transformation.</p><p><strong>Material and methods: </strong>The sample consisted of 40 cases, of which 20 oral leukoplakia (OL) were classified according to World Health Organization and binary systems for grading oral epithelial dysplasia (OED) as well as 20 oral squamous cell carcinoma (OSCC), moderately or poorly differentiated. Type I collagen was analysed by immunohistochemistry, Fisher's exact test and chi-square test evaluated the clinical data. One-way ANOVA and Tukey's test were applied to analyse type I collagen expression between groups. Associations between data were analysed by two-way ANOVA with Sidak's multiple comparison test.</p><p><strong>Results: </strong>Men were most affected with OSCC (90%) and 60% of OL were in women (P = 0.0022). Type I collagen expression was higher in mild (P = 0.04) and moderate (P = 0.03) OED than moderately differentiated OSCC. Severe OED had a lower expression when compared with moderate OED (P = 0.01) and well differentiated OSCC (P = 0.02). The binary system showed that low-risk had more collagen expression than high-risk (P = 0.03) and severe OED (P = 0.03).</p><p><strong>Conclusions: </strong>The binary system allows more effective correlations to be established between stromal changes and oral epithelial dysplasia. The higher expression of collagen in the benign lesions may represent changes in the microenvironment that will favour the process of epithelial transformation and the establishment of a more aggressive disease.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 3","pages":"e3"},"PeriodicalIF":1.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
João Paulo da Silva Guilherme, Marcelo Santos Bahia, Yuri de Lima Medeiros, Marcella Yumi Kadooka, Marcelo Tarcísio Martins, Isabel Cristina Gonçalves Leite, Marcos Vinicius Queiroz de Paula
{"title":"Is Surgical Removal of Asymptomatic Third Molars in the Horizontal III-C Position Advisable? A Pilot Study of Tomographic Evaluation.","authors":"João Paulo da Silva Guilherme, Marcelo Santos Bahia, Yuri de Lima Medeiros, Marcella Yumi Kadooka, Marcelo Tarcísio Martins, Isabel Cristina Gonçalves Leite, Marcos Vinicius Queiroz de Paula","doi":"10.5037/jomr.2024.15304","DOIUrl":"10.5037/jomr.2024.15304","url":null,"abstract":"<p><strong>Objectives: </strong>This cross-sectional study aimed to measure the distance between the buccal and lingual cortical bones and its relation with the mandibular canal roof of third molars classified as III-C position according to Winter, Pell and Gregory classifications in cone-beam computed tomography.</p><p><strong>Material and methods: </strong>A total of 140 lower third molars were classified according to Winter, Pell and Gregory. The distance between the buccal external cortex and the lingual external cortex was measured at 25%, 50% and 75% of the distance to the roof of the mandibular canal in parasagittal sections of teeth classified in horizontal III-C position. The presence or absence of lesions associated with the elements in this position was observed. Descriptive statistical analysis was performed and the intra-examiner agreement was calculated using the Bland-Altman and t-test methods (0.88 and 0.91, respectively). The significance level used was 5% (P ≤ 0.05).</p><p><strong>Results: </strong>Seventy patients (29.4 [SD 8.8] years, 54% women and 46% men) were included. Fourteen (10%) third molars were classified in horizontal III-C position. The average measurements taken were 1.78, 1.1 and 1.53 mm for the distances between the buccal external cortex and lingual external cortex, at 25%, 50% and 75% of the distance to the roof of the mandibular canal, respectively. No pathological conditions associated with the included elements were observed.</p><p><strong>Conclusions: </strong>Analysis of cone-beam computed tomography parasagittal sections of third molars classified in horizontal III-C position, revealed proximity of impacted teeth to the mandibular canal roof, mainly in the midline between the buccal and lingual external cortices.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 3","pages":"e4"},"PeriodicalIF":1.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk of Narrow Upper Airway in Class II Children with Large Horizontal Maxillary Overjet Assessed By Acoustic Reflection: a Case-Control Study.","authors":"Camilla Hansen, Merete Bakke, Liselotte Sonnesen","doi":"10.5037/jomr.2024.15305","DOIUrl":"10.5037/jomr.2024.15305","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this case-control study was to examine upper airway by acoustic reflection in class II children with large horizontal maxillary overjet compared to children with neutral occlusion.</p><p><strong>Material and methods: </strong>The study group included children of 9 to 14 years with class II and large horizontal maxillary overjet (≥ 6 mm) compared to children with neutral occlusion (controls). Acoustic pharyngometry and rhinometry were performed in natural head position. Differences between groups were tested by chi-square test, general linear model (adjusted for age, gender and body mass index [BMI]), and Mann-Whitney test.</p><p><strong>Results: </strong>The study and control group consisted of 37 (boys: 19, girls: 18) and 32 (boys: 16, girls: 16) participants, respectively. No significant differences in age, gender, and BMI were found between the groups. For the acoustic rhinometry measurements significantly increased resistance (P = 0.04), reduced volume (P = 0.03) and distance to minimal cross-section area (MCA) (P = 0.035) were found in the study group, but only for the right nostril. However, significantly reduced MCA for both nostrils was found in the study group (P = 0.025 to 0.04). No significant differences in acoustic pharyngometry measurements were found.</p><p><strong>Conclusions: </strong>Nasal airway dimensions were significantly reduced, and nasal resistance was significantly increased in the study group compared to controls. Thus, class II and large overjet with indication for growth adaptive treatment may be a risk factor for sleep-disordered breathing. In the future, orthodontic paediatric patients may benefit from non-invasive risk assessment of narrow upper airway using acoustic reflection.</p>","PeriodicalId":53254,"journal":{"name":"eJournal of Oral Maxillofacial Research","volume":"15 3","pages":"e5"},"PeriodicalIF":1.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}