Marine Life Science & Technology最新文献

{"title":"Investigating the psammophilic karyorelictean ciliate families Kentrophoridae and Cryptopharyngidae (Protista, Ciliophora): molecular phylogeny, geographic distributions and a brief revision including descriptions of a new genus, a new species and a new combination.","authors":"Mingzhen Ma, Danxu Tang, Wen Song, Lifang Li, Igor V Dovgal, Khaled A S Al-Rasheid, Hunter N Hines, Ying Yan","doi":"10.1007/s42995-024-00266-6","DOIUrl":"https://doi.org/10.1007/s42995-024-00266-6","url":null,"abstract":"<p><p>Psammophillic ciliates are an integral part of the foodweb despite being underrepresented in terms of molecular phylogeny and modern taxonomy. To investigate the karyorelictean group, sampling was conducted in interstitial marine habitats in China for ciliates living between the sand grains, resulting in an examination of the families Cryptopharyngidae Jankowski, 1980 and Kentrophoridae Jankowski, 1980. Three species, i.e., <i>Cryptopharynx setigerus</i> Kahl, 1928, <i>Kentrophoros fasciolatus</i> (Sauerbrey, 1928) Foissner, 1995 and <i>K. fistulosus</i> (Fauré-Fremiet, 1950) Foissner, 1995, are clearly recognized as being cosmopolitan, while other species await further recording. Phylogenetic analyses were carried out based on updated data. These revealed that the families Cryptopharyngidae and Kentrophoridae are closely related, and most genera studied are monophyletic, although <i>Cryptopharynx qingdaoensis</i> n. sp. is located within the Kentrophoridae branch. Brief revisions of two genera, namely <i>Cryptopharynx</i> Kahl, 1928 and <i>Kentrophoros</i> Sauerbrey, 1928, are provided including keys to the identification of nine species belonging to the former and 12 species belonging to the latter. One new genus, <i>Parakentrophoros</i> n. gen., and one new species, <i>Cryptopharynx qingdaoensis</i> n. sp., are described and a new combination, <i>Parakentrophoros canalis</i> (Wright, 1982) n. comb., is established. Finally, it appears that the subapical oral apparatus undergoes a gradual degeneration process from Cryptopharyngidae to Kentrophoridae.</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"7 1","pages":"23-49"},"PeriodicalIF":5.8,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Linking multi-gene and morphological data in the subclass Scuticociliatia (Protista, Ciliophora) with establishment of the new family Homalogastridae fam. nov.","authors":"Mingjian Liu, Limin Jiang, Zhe Zhang, Fan Wei, Honggang Ma, Zigui Chen, Khaled A S Al-Rasheid, Hunter N Hines, Chundi Wang","doi":"10.1007/s42995-024-00264-8","DOIUrl":"https://doi.org/10.1007/s42995-024-00264-8","url":null,"abstract":"<p><p>Scuticociliatia is one of the most species-rich subclasses in the phylum Ciliophora. The evolutionary relationships among Scuticociliatia groups have long been very unclear due to the homogeneity of morphology and insufficiency of molecular data. With morphological and multi-gene-based molecular data presented here, the evolutionary phylogeny of several Scuticociliatia taxa that were hitherto especially poorly defined is analyzed and discussed. The results indicate: (1) all scuticociliates cluster into two well supported and one poorly supported group, representing three order-level taxa; (2) with the support of both morphological and molecular data, a new family Homalogastridae fam. nov. is proposed in the order Philasterida; (3) <i>Parauronema</i> is formally transferred to Uronematidae and <i>Potomacus</i> is treated as <i>incertae sedis</i> in the order Philasterida, therefore Parauronematidae is proposed to be a junior synonym of Uronematidae; (4) the genus <i>Madsenia</i> and the species <i>Parauronema longum</i> and <i>Pseudocyclidium longum</i> are treated as <i>incertae sedis</i>, while the genus <i>Protophyra</i> should be maintained in the family Ancistridae. In addition, the putative secondary structure of internal transcribed spacer 2 (ITS2) of representative taxa from the three orders of Scuticociliatia are analyzed, and consensus structures and nucleotide composition in each order are exhibited.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s42995-024-00264-8.</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"7 1","pages":"1-22"},"PeriodicalIF":5.8,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Otolith biogeochemistry reveals possible impacts of extreme climate events on population connectivity of a highly migratory fish, Japanese Spanish mackerel <i>Scomberomorus niphonius</i>.","authors":"Xindong Pan, Yong Chen, Tao Jiang, Jian Yang, Yongjun Tian","doi":"10.1007/s42995-024-00267-5","DOIUrl":"https://doi.org/10.1007/s42995-024-00267-5","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1007/s42995-024-00229-x.].</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"7 1","pages":"203"},"PeriodicalIF":5.8,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical interactions between kelp <i>Macrocystis pyrifera</i> and symbiotic bacteria under elevated CO₂ condition.","authors":"Xiaowen Zhang, Tianle Xi, Yitao Wang, Xiao Fan, Dong Xu, Pengyan Zhang, Ke Sun, Yan Zhang, Jian Ma, Naihao Ye","doi":"10.1007/s42995-024-00259-5","DOIUrl":"https://doi.org/10.1007/s42995-024-00259-5","url":null,"abstract":"<p><p>Kelps are pivotal to temperate coastal ecosystems, providing essential habitat and nutrients for diverse marine life, and significantly enhancing local biodiversity. The impacts of elevated CO₂ levels on kelps may induce far-reaching effects throughout the marine food web, with potential consequences for biodiversity and ecosystem functions. This study considers the kelp <i>Macrocystis pyrifera</i> and its symbiotic microorganisms as a holistic functional unit (holobiont) to examine their collective response to heightened CO₂ levels. Over a 4 month cultivation from the fertilization of <i>M. pyrifera</i> gametes to the development of juvenile sporophytes, our findings reveal that elevated CO₂ levels influence the structure of the <i>M. pyrifera</i> symbiotic microbiome, alter metabolic profiles, and reshape microbe-metabolite interactions using 16S rRNA amplicon sequencing and liquid chromatography coupled to mass spectrometry analysis. Notably, <i>Dinoroseobacter</i>, <i>Sulfitobacter</i>, <i>Methylotenera</i>, <i>Hyphomonas</i>, Milano-WF1B-44 and <i>Methylophaga</i> were selected as microbiome biomarkers, which showed significant increases in comparative abundance with elevated CO₂ levels. Stress-response molecules including fatty-acid metabolites, oxylipins, and hormone-like compounds such as methyl jasmonate and prostaglandin F2a emerged as critical metabolomic indicators. We propose that elevated CO₂ puts certain stress on the <i>M. pyrifera</i> holobiont, prompting the release of these stress-response molecules. Moreover, these molecules may aid the kelp's adaptation by modulating the microbial community structure, particularly influencing potential pathogenic bacteria, to cope with environmental change. These results will enrich the baseline data related to the chemical interactions between the microbiota and <i>M. pyrifera</i> and provide clues for predicting the resilience of kelps to future climate change.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s42995-024-00259-5.</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"6 4","pages":"700-712"},"PeriodicalIF":5.8,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11602886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the potential for global offshore finfish mariculture.","authors":"Shuang-En Yu, Ming-Ling Liao, Shuang-Lin Dong, Yun-Wei Dong","doi":"10.1007/s42995-024-00257-7","DOIUrl":"https://doi.org/10.1007/s42995-024-00257-7","url":null,"abstract":"<p><p>Understanding the potential areas suitable for offshore mariculture is crucial to global seafood security. Here, we map the potential global offshore mariculture areas for 23 principal commercial finfish using an ensemble model. The model involves the temporal-spatial heterogeneity of environments and constraints of temperature-dependent hypoxia and cold edges of cultured finfish by metabolic index and lower thermal safety margin, respectively. Our results show that currently, there is 9.16 ± 1.22 million km² of potentially suitable area for offshore finfish mariculture. Under climate change, the potential suitable area will be reduced to between 86.7% and 91.7% of the current size by 2050. Compared to the decline in tropical regions, the expanded potential areas in temperate and polar regions will become more important for global seafood security. The potential offshore finfish mariculture area responds differently to global change among species, and cold-water finfish may benefit from global warming. Overall, despite changes in the distribution of global offshore mariculture areas and replacements of local potential mariculture species, offshore finfish mariculture still holds immense potential in the future.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s42995-024-00257-7.</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"6 4","pages":"651-664"},"PeriodicalIF":5.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11602909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taxonomy and systematic positions of three new <i>Callistoctopus</i> species (Octopoda, Octopodidae) discovered in coastal waters of China.","authors":"Yan Tang, Xiaodong Zheng, Chungcheng Lu","doi":"10.1007/s42995-024-00258-6","DOIUrl":"https://doi.org/10.1007/s42995-024-00258-6","url":null,"abstract":"<p><p>The genus <i>Callistoctopus</i> comprises 13 species, and has been reported mostly in the Western Pacific Ocean. Here, we described three new species from China, <i>Ca. paucilamellus</i> sp. nov., <i>Ca. sparsus</i> sp. nov., and <i>Ca. gracilis</i> sp. nov., based on morphometric and meristic characteristics. The diagnoses, descriptions and detailed morphometric data are provided for each species. The cytochrome c oxidase I (COI) genes of the three new species are sequenced, and compared with related species and analyzed for their systematic positions. Both phylogenetic trees constructed using three mitochondrial genes (12S rRNA, 16S rRNA, COI) and one nuclear gene (Rhodopsin) revealed that our new species formed into two distinct clades with strong support values. One clade included <i>Ca. gracilis</i> sp. nov., <i>Ca.</i> sp. 1, <i>Ca. xiaohongxu</i>, <i>Ca. tenuipes</i> and <i>Ca. paucilamellus</i> sp. nov., which clustered together. The other clade showed that <i>Ca. sparsus</i> sp. nov. was closely related to <i>Ca.</i> sp. 2 and <i>Ca.</i> sp. 3. <i>Ca. luteus</i> and <i>Ca. macropus</i> were located at the base of the <i>Callistoctopus</i> group. Based on our integrative studies, both morphological and molecular evidence suggested strongly that <i>O. minor</i> is more likely to be classified as a species of <i>Callistoctopus</i>. Morphological comparisons were made between the three new species and related taxa, which could be recognized based on the 7-8 gill lamellae of each demibranch, numerous small black spots on the subdermal layer of the arms, and an elongated body.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s42995-024-00258-6.</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"6 4","pages":"750-767"},"PeriodicalIF":5.8,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11602926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contribution of environmental and biological factors to bacterial community structure and stability in a subalpine lake.","authors":"Ping Guo, Cui Li, Jinxian Liu, Tiehang Wu, Baofeng Chai","doi":"10.1007/s42995-024-00256-8","DOIUrl":"https://doi.org/10.1007/s42995-024-00256-8","url":null,"abstract":"<p><p>Bacterial community play an essential role in regulating water quality and the global biogeochemical cycle in aquatic ecosystems. However, how trophic interactions (i.e., biotic factors) regulate the diversity and composition of bacterial community in lake ecosystems remains unknown. Here, we employed DNA meta-barcoding of water samples to explore the impact of bacterivorous protozoans on the bacterial community. The results showed significant seasonal variations in the diversity and composition of both bacterial and protist communities. The composition of bacterivorous protozoans was identified as the primary predictor for the bacterial community alpha diversity in spring and summer, and for beta diversity in spring and autumn, indicating that biotic interactions play a greater role in driving the diversity of bacterial community across different seasons. Biological factors were more important than environmental factors for explaining the variations in the relative abundance of several bacterial genera (i.e., <i>Pseudoxanthomonas</i>, <i>hgcI_clade</i>, and <i>Pseudorhodobacter</i>). Network analyses showed that bacterial networks differed among seasons, and the autumn network exhibited the highest stability. Our findings indicated that the bacterial community stability was significantly affected by environmental factors, specifically SO₄ ^2-and PO₄ ^3-, rather than bacterivorous protozoans. Overall, our findings provide new perspectives on the role of trophic interactions in maintaining the structure of bacterial community in different seasons, and enhance our understanding of the bacterial community assembly in lake ecosystems.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s42995-024-00256-8.</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"7 1","pages":"176-186"},"PeriodicalIF":5.8,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Understanding the role of microbes in health and disease of farmed aquatic organisms.","authors":"Cristiane C Thompson, Wilson Wasielesky, Felipe Landuci, Michele S Lima, Leonardo Bacha, Luciane M Perazzolo, Cátia Lourenço-Marques, Florbela Soares, Pedro Pousão-Ferreira, Larry Hanson, Bruno Gomez-Gil, Mateus Thompson, Tooba Varasteh, Tatiana A Silva, Jean Swings, Xiao-Hua Zhang, Wanderley de Souza, Fabiano L Thompson","doi":"10.1007/s42995-024-00261-x","DOIUrl":"https://doi.org/10.1007/s42995-024-00261-x","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1007/s42995-024-00248-8.].</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"7 2","pages":"413"},"PeriodicalIF":5.8,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The first dimeric indole-diterpenoids from a marine-derived <i>Penicillium</i> sp. fungus and their potential for anti-obesity drugs.","authors":"Hui-Fang Du, Lei Li, Ya-Hui Zhang, Xu Wang, Cheng-Yan Zhou, Hua-Jie Zhu, Charles U Pittman, Jia-Wen Shou, Fei Cao","doi":"10.1007/s42995-024-00253-x","DOIUrl":"https://doi.org/10.1007/s42995-024-00253-x","url":null,"abstract":"<p><p>Obesity has become a worldwide health problem. Seeking natural products with anti-obesity activity from lots of fungi has drawn the attention of pharmacologists. In our study, dipenipenoids A and B (<b>1</b> and <b>2</b>), the first dimeric indole-diterpenoids with a rare C-20-C-22' linkage, and their monomers (<b>3</b> and <b>4</b>), were isolated from a marine-derived <i>Penicillium</i> sp. CF-06 fungus from <i>Suaeda salsa</i>. The absolute configurations of <b>1</b>-<b>3</b> were assigned by the calculated TDDFT ECD method. The structure of <b>4</b> was verified by a single-crystal X-ray diffraction method for the first time. Interestingly, <b>1</b> and <b>2</b> displayed significant effects on the differentiation of 3T3-L1 adipocytes by down-regulating the expression of peroxisome proliferator-activated receptor gamma (PPAR<i>γ</i>) and CCAAT/enhancer binding protein alpha (C/EBP<i>α</i>) proteins, while monomers <b>3</b> and <b>4</b> exhibited no activity. Molecular docking results explained the mechanism that the interaction between dimer <b>1</b> and PPAR<i>γ</i> was stronger than that between monomer <b>3</b> and PPAR<i>γ</i>. Our research could provide new insight for the discovery of anti-obesity drugs.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s42995-024-00253-x.</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"7 1","pages":"120-131"},"PeriodicalIF":5.8,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tidal levels significantly change bacterial community composition in a tropical estuary during the dry season.","authors":"Pablo Aguilar, Chantima Piyapong, Nitcha Chamroensaksri, Pachoenchoke Jintasaeranee, Ruben Sommaruga","doi":"10.1007/s42995-024-00254-w","DOIUrl":"https://doi.org/10.1007/s42995-024-00254-w","url":null,"abstract":"<p><p>Estuaries are usually characterized by strong spatial and temporal variability in water physicochemical conditions and are often largely affected by human activities. One important source of variability is caused by tides that can swiftly alter not only physicochemical conditions but also the abundance and composition of the biota. The effect of the diurnal tidal cycle on microbial community composition during different seasons remains uncertain, although this knowledge underlies having effective monitoring programs for water quality and potential identification of health risk conditions. In this study, we assessed the bacterioplankton community composition and diversity across four tidal water levels in a tropical estuary characterized by a mixed semidiurnal tide regime (i.e., two high and two low tides of varying amplitudes) during both dry and wet seasons. The bacterial community composition varied significantly among the four tidal levels, but only during the dry season, when the influence of the seawater intrusion was largest. Bacterial indicators' taxa identified using the Indicator Value Index were found within Cyanobacteria, Actinobacteriota, Bacteroidota, and Proteobacteria. The indicator taxon <i>Cyanobium</i> sp. had a prominent presence across multiple tidal levels. The main predicted phenotypes of the bacterial communities were associated with potential pathogenicity, gram-negative, and biofilm formation traits. While there were no marked predicted phenotypic differences between seasons, pathogenic and gram-negative traits were more prevalent in the dry season, while biofilm formation traits dominated in the wet season. Overall, our findings underscore the intricate relationship between river hydrodynamics and bacterial composition variability and hint a significant human impact on the water quality of the Bangpakong River.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s42995-024-00254-w.</p>","PeriodicalId":53218,"journal":{"name":"Marine Life Science & Technology","volume":"7 1","pages":"144-156"},"PeriodicalIF":5.8,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}